a Semmelweis Egyetem
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November 6 (Thursday)

Opening

Ágoston Szél, Rector of Semmelweis University
Laszló Hunyady, Dean of Medical School
György Losonczy, Conference Chair

8:30 Opening address

Agoston Szel, Rector of Semmefvveis University

I. Update on bronchial asthma and chronic obstructive pulmonary disease (COPD)

Chair: lldikó Horvath

9:00 Peter J. Bames, Imperial College, London, UK

New targets and treatments for COPD

9:25 lldikó Horvath, Semmefvveis University and National Koranyi Institute, Budapest, Hungary

Big data in asthma phenotyping

9:45 András Bikov

Innovative approaches in exhaled biomarker measurements

10:10 Balazs Antus, National Koranyi Institute, Budapest, Hungary

Airway biomarkers in COPD

10:30 Discussion

10:40 Break

II. New therapeutic concepts in obstructive lung diseases

Chair: Gabor Horvath

11:00 Adam Wanner, University of Miami, USA

Alpha-1 antitrypsin deficiency-related COPD

11:25 Andreas Schmid, University of Miami, USA

Bronchiectasis: challenges in diagnosis and treatment

11:50 Matthias Salathe, University of Miami, USA

Novel approaches to correct cystic fibrosis related airway disease: relevance to COPD?

12:15 Gabor Horvath, Semmefvveis University, Budapest, Hungary

Inhaled bronchodilators: mechanisms of drugs absorption in the airway

12:35 Discussion

12:45 Lunch

lll. Non-invasive ventilation

Chair: Andras Lorx

14:00 Wolfram Windisch, Merheim Lungenklinik, Cologne, Germany

Home non-invasive ventilation in COPD: what is the best approach?

14:25 Jozsef Lukacsovits, Semmelweis University, Budapest, Hungary

Physiological changes during low- and high-intensity non-invasive ventilation

14:45 Piero Ceriana, Pavia, Italy

The difficult -to- wean patient: role of rehabilitation and non-invasive ventilation

15:10 Andras Lorx, Semmelweis University, Budapest, Hungary

The grey zone: indications and limitations of non-invasive ventilation in acute settings

15:30 Olli Polo, University of Turku, Finland

Sleep apnea and the autonomic nervous system

15:55 Discussion

16:05 Break

IV. Pulmonary hypertension

Chair: Kristof Karlocai

16:20 Anna Csiszar, University of Oklahoma, Oklahoma City, USA

Ageing induced functional and phenotypic alterations in vascular cells

16:45 Gabor Kovacs Jr., Medical University of Graz, Austria

Right heart catheter at rest and exercise

17:05 Horst Olschewski, Medical University of Graz, Austria

New therapies for pulmonary hypertension

17:25 Kristof Karlocai, Semmelweis University, Budapest, Hungary

Pregnancy and pulmonary hypertension

17:45 Discussion

November 7 (Friday)

V. Rehabilitation Exercise physiology

Chair: Attila Somfay

8:30 Richard H. Casaburi, University of Califomia, Los Angeles, USA

Pulmonary rehabilitation: a new focus on physical activity

8:55 Attila Somfay, University of Szeged, Szeged, Hungary

Pharmacological and non-pharmacological interventions to reduce dynamic hyperinflation in patients with COPD

9:15 Peter Apor; Semmelweis University, Budapest

Sarcopenia in pulmonology, cardiology and geriatrics

9:35 Miklós Tóth, Serrmelweis University, Budapest, Hungary

Exercise testing and mass-spectrometry

9:55 Discussion

10:05 Break

VI. Lung cancer 1

Chairs: Judit Moldvay

10:25 Paolo Boffetta, Tisch Cancer Institute, New York, USA

Screening of lung cancer

11:50 Judit Moldvay, Semmelweis University, Budapest, Hungary

Tight junction proteins in lung cancer

12:10 Helmuth Popper; University of Graz, Austria

Molecular pathology of non-small cell lung cancer

12:35 Mir Ali Reza Hoda, Medical University of Vienna, Austria

Recent developments and new therapeutic strategies in malignant pleural mesothelioma

12.55 Discussion

13:05 Lunch

VII. Asthma in pregnancy

Chairs: Lilla Tamasi

14:15 Christopher VII. G. Redman, John Redcliffe, Oxford, UK

Immunology of placentation

14:45 Lilla Tamasi, Semmelweis University, Budapest, Hungary

Asthma in pregnancy: immune changes and monitoring

15:00 Michael Schatz, Kaiser Permanente, San Diego, USA

Asthma in pregnancy: diagnosis and treatment

15:25 János Rigó, Semmelweis University, Budapest, Hungary

Medical disorders and preeclampsia

15:45 Discussion

15:55 Break

VIII. Innate lymphoid cells and bronchial asthma

Chair: Zsolt Komlósi

16:15 Mubeccel Akdis, Swiss Institute of Allergy and Asthma Research, Davos, Switzerland

Mechanisms of peripheral tolerance to allergens

16:40 Zsolt Komlósi, Semmelweis University, Budapest, Hungary

lmmunoregulatory role for ,type 3" innate lymphoid cells

17:00 Burkhard Ludewig, St. Gallen, Switzerland

Stromal cells regulate lymphoid organ development and immune responsiveness

17:25 Discussion

17:35 Break

IX. Lung cancer 2

Chair: György Losonczy

17:45 Jean-Paul Sculier; Free University of Brussels, Belgium

Targeted treatment of advanced stage non-small cell lung cancer

18:10 György Losonczy, Semmelweis University, Budapest, Hungary

Risk and prevention of cisplatin nephrotoxicity

18:25 Chris Baylis, University of Gainesville, Florida, USA

Physiology of toxic acute renal failure

18:50 Discussion

20:00 Gala Dinner (Marble Hall of the Museum of Military History, Buda Castle) November 8, Saturday

X. Pulmonary complications in solid organ transplantation

Chair: Veronika Müller

8:30 Uwe Heemann, Technical University Munich

Optimizing immunosuppressive therapies to prevent pulmonary complications

8:55 Veronika Müller; Semmelweis University, Budapest, Hungary Pleuropulmonary changes in immunocompromized patients: infection or underlying disease?

9:15 György Lang, Semmelweis University, Budapest and Medical University of Vienna, Austria

Bridge therapies from end-stage lung disease to lung transplantation

9:35 Nandor Marczin, Imperial College London, London, UK

Optimizing donor lungs and perioperative recipient care in lung transplantation

10:00 Discussion

10:10 Break

10:25 Semmelweis Budapest Award Ceremony

Award Winner: György Klein, Nobel Laureate
Award is presented by Ágoston Szél, Rector of Semmelweis University

11.00 Closing remarks

György Losonczy