Assistant Director, Basic Science Research Program, Center for Prostate Disease Research.
Dr. Albert Dobi joined the Center for Prostate Disease Research (CPDR) in September 2003 and became the Assistant Director
of Basic Science Research Program in March 2007. He is the Chief of the Section for Gene Regulation and Bioinformatics, a
Research Assistant Professor of Surgery at the Department of Surgery, Uniformed Services University of the Health Sciences
(USUHS) and also he is a member of The United States Military Cancer Institute (USMCI).
Dr. Dobi integrates prostate cancer research activities within the Basic Research Science Program and leads research efforts
towards the exploration of regulation, expression and functions of prostate cancer-associated genes, such as, ERG and androgenregulated genes. His specific goals are: to determine the relationship between oncogenic processes and androgen receptor
and to develop new approaches towards the treatment of prostate cancer by synergizing state-of-the-art molecular and in silico bioinformatic methodologies.
Dr. Dobi earned his doctorate in biology from the Jozsef Attila University, in Szeged, Hungary. As a recipient of the prestigious
U.S. National Institutes of Health Fogarty Visiting Fellowship, from 1990 to 1992 Dr. Dobi received postdoctoral training under the mentorship of Dr. Dean H. Hamer at the National Cancer Institute (NCI). In this capacity, he formulated a model to elucidate the gene regulatory basis of a cellular self-defense response to copper stress. As a Fogarty Fellow and later Visiting Associate Scientist in the Laboratory of Developmental
Neurobiology at the National Institute of Child Health and Human Development (NICHD), he was responsible for numerous
successful projects involving gene characterization and transcription regulation.
Dr. Dobi made the transition to the Uniformed Services University (1998–2003), Department of Anatomy, Physiology
and Genetics, where his research focused on identifying important transcription factors in brain development. Within the multi-disciplinary setting of CPDR Dr. Dobi’s endeavors revealed that C-MYC is a downstream target of ERG oncogene.
His research also contributed towards the discovery of dominant ERG splice variants in prostate cancer.
Dr. Dobi is the recipient of several awards such as the Sustained Superior Performance Award for Continued Superior
Performance, given by the Henry M. Jackson Foundation for the Advancement of Military Medicine, the prestigious Prostate
Cancer Foundation Competitive Award, and award from the Congressionally Directed Medical Research Program. He authored numerous peer-reviewed original reports and serves as reviewer for scientific journals. Dr. Dobi supervises and trains researchers, residents and students in the CPDR Basic Science Research Program.
Scientific Awards: 23