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PRINCIPAL QUESTIONS OF THE GENOMIC MEDICINE: PREDICTION, PREVENTION AND PERSONALIZED TREATMENT

SEMMELWEIS SYMPOSIUM

2012 – PROGRAM PLAN

2012. NOVEMBER 09.

09.00 – 09.25
OPENING CEREMONY

Ágoston Szél and Mária Judit Molnár

Welcome
Szél, Ágoston (Rector of the Semmelweis University)

Semmelweis University facing the new era of medicine: Personalized Healthcare
Molnár, Mária Judit (Chair of the Symposium)

09.25 – 11.15
IMPLEMENTING A PERSONALIZED MEDICINE STRATEGY – IS THERE LIGHT AT THE END OF THE TUNNEL?

Chairpersons: László Hunyady and György Németh

Predictive diagnostics, targeted preventive measures and personalized treatment:new philosophy in health care.
Golubnitschaja, Olga (General Secretary of the European Personalized Medicine Association, Brusssels, Belgium)

Personalized medicine: from theory to the clinical practice
Németh, György (President of the Hungarian Society of Personalized Medicine, Budapest, Hungary)

The triad of success in personalized medicine: pharmacogenomics, biotechnology and regulatory issues from a Central European perspective
Nagy, László (University of Debrecen, Institute of Personalized Medicine, Debrecen, Hungary)

Key dehydrogenases in the mitochondrial generation of reactive oxygen species
Ádám, Veronika (Semmelweis University, Budapest, Hungary)

Discussion

11.15 – 11.40
COFFE BREAK

11.40 – 13.00
IMMUNOMICS

Chairpersons: András Falus and Edit Búzás

High-throughput Immunomics: data mining of vaccine targets in viral pathogens
Brusic, Vladimir (Harvard Medical School, Boston, USA)

Genomic investigations in asthma
Szalai, Csaba (Hungarian Academy of Sciences, Semmelweis
University, Budapest, Hungary)

Systems biology approach in tumor genomics and epigenetics
Falus, András (Semmelweis University, Budapest, Hungary)

Discussion

13.00 – 13.45
LUNCH BREAK

13.45 – 15.45
METABOLOMICS

Chairpersons: Zoltán Takáts and László Szõnyi

The modern methods of metabolomics and proteomics
Kertész, Vilmos (Oak Ridge National Laboratories, USA)

Population level newborn screening for inherited metabolic disorders and other genetic risk factors
Szõnyi, László (Semmelweis University, Pediatric Clinics 1Budapest, Hungary).

Imaging mass spectrometry in predictive tumor diagnostics
Römpp, Andreas (Justus Liebig University, Giessen, Germany)

Mass spectrometry methods as confirmation analyses in the diagnosis of inherited metabolic disorders
Szatmári, Ildikó (Semmelweis University, Cell Screen ResearchCenter, Budapest, Hungary)

Mass spectrometric profiling of biological tissues – a comprehensive tool for personalized medicine
Takáts, Zoltán (Semmelweis University, Cell Screen Research Center, Budapest, Hungary/Imperial College Department of Surgery and Cancer, London, UK)

Discussion

15.45. – 16.00 COFFE BREAK

16.00 – 17.40
PERSONALIZED CARDIOLOGY THE WAY TO THE OPTIMAL PREVENTION AND THERAPY

Chairpersons: Béla Merkely and Zoltán Nagy

Reduction of salt intake in the general population:recommendations to be taken cum grano salis
Staessen, Jan A. (University of Leuven, Leuven, Belgium)

Pilot results of the Budakalasz Epidemiology Study, a prospective Central-European population-based survey
Szelid, Zsolt (Semmelweis University, Budapest, Hungary)

Heart failure epidemiology in Hungary
Soós, Pál (Semmelweis University, Budapest, Hungary)

Cardiac-CT in population screening
Maurovich-Horváth, Pál (Semmelweis University, Budapest, Hungary)

Discussion

17.40 – 18.45
POSTER SESSION

PREDICTION OF TREATMENT EFFECTIVITY AND SIDE EFFECTS
Chairpersons: Gábor Kovács and Csaba Szalai

PREDICTION AND PREVENTION OF CARDIOVASCULAR AND CEREBROVASCULAR DISORDERS
Chairpersons: Pál Soós and Ildikó Vastagh

THE GENETIC BACKGROUND OF RARE DISEASES
Chairpersons: György Fekete and Kálmán Tory

BIOMARKER RESEARCH
Chairpersons: Christos Chinopoulos and Péter Igaz

GENETIC AND SOCIOBEHAVIORAL FACTORS PREDISPOSING TO PSYCHIATRIC DISORDERS
Chairpersons: István Bitter and György Purebl

2 0 1 2 N O V E M B E R 1 0 .

08.30 – 10.00 NEUROPSYCHOPHARMACOLOGY

Chairpersons: György Bagdy and Károly Mirnics

GABA-ergic dysfunction in schizophrenia: from postmortem studies to animal models
Mirnics, Károly (Vanderbilt Kennedy Center, Nashville, USA)

Monoamine-endocannabinoid interactions in anxiety and depression: relevance to personalized medicine
Bagdy, György (Semmelweis University, Budapest, Hungary)

Exploring serotonin function in the human brain using phMRI
McKie, Shanke (Neuroscience and Psychiatry Unit, University of Manchester, UK)

Discussion

10.00 – 10.20 COFFE BREAK

10.20 – 12.15 GENOMIC NEUROLOGY: PREDICTION AND TREATMENT OF NEUROLOGICAL DISORDERS

Chairpersons: András Spat and Gábor Kovács

The expanding field of the mitochondrial medicine
Wartiovara, Anu (University of Helsinki, Helsinki, Finland)

Lessons from GWAS in cognitive decline
Kovács, Gábor (Medical University of Vienna, Vienna, Austria / Semmelweis University, Budapest, Hungary)

Translational molecular neuroimaging
Gulyás, Balázs (Karolinska University, Stockholm, Sweden)

Medical and biological insights from genetic studies of rare inherited neurological disorders
Weis, Joachim (RWTH University Hospital, Aachen, Germany)

Discussion

12.15 – 12.35
COFFE BREAK

12.35 – 14.05
PERSONALIZED DECISION MAKING IN THE ERA OF EVIDENCE-BASED NEUROLOGY

Chairpersons: Daniel Bereczki and Peter Langhorne

Personalized medicine and evidence based medicine: enemies or brothers-in-arms?
Bereczki, Dániel (Semmelweis University, Budapest, Hungary)

Systematic reviews in stroke care: have they changed clinical practice?
Langhorne, Peter (University Glasgow, Glasgow, UK)

Coma and disorders of consciousness
Charland-Verville, Vanessa, (University Liege, Liege, Belgium)

Discussion

14.05. TEST

14.20-
CLOSING CEREMONY