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| Open the list of posters |
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November 7 (Thursday) evening | |
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Opening ceremony | |
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14.00- | Registration |
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18.00-18.15 | Welcome and introduction |
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Ágoston Szél | |
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Rector of Semmelweis University | |
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18.15-18.45 | Semmelweis Award 2013 – Laudation and video presentation |
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Award recipient: | |
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György Oláh (Los Angeles, USA) | |
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18.45-19.30 | Opening lecture |
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András Falus (Budapest, Hungary) | |
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„Me, myself and us”: Microbiota ecosystems in inflammation regulation | |
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19.30-21.30 | Welcome reception |
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November 8 (Friday) morning | |
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Molecular mechanisms in inflammatory diseases | |
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Chairs: | László Kovács (Szeged, Hungary),
Andrew Luster (Boston, USA) |
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8.30-9.00 | Steffen Gay (Zürich, Switzerland) |
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Epigenetic regulation in rheumatic diseases | |
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9.00-9.30 | Paul Winyard (Exeter, UK) |
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Oxidative stress and biomarkers in human inflammatory joint disease | |
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9.30-9.45 | Sofia de Oliveira (Murcia, Spain) |
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ATP and Calcium modulate the inflammatory response via Duox 1 activation and hydrogen peroxide release | |
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9.45-10.00 | Chaekyun Kim (Incheon, Korea) |
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The role of NADPH oxidase-derived taurine chloramine in collagen-induced arthritis | |
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10.00-10.15 | Gábor Zahuczky (Debrecen, Hungary) |
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Distinct gene panels predict response to infliximab therapy from peripheral blood in rheumatoid arthritis and Crohn’s disease | |
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10.15-10.30 | Biljana Smiljanovic (Berlin, Germany) |
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From transcriptome data to protein biomarkers in RA: joint compartment and monocytes outperform serum as sample material for diagnosis | |
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10.30-11.00 | Coffee break |
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11.00-11.45 | Keynote lecture |
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Ravinder Maini (London, UK) | |
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Revolutionizing therapy of rheumatoid arthritis by TNF blockers: as it happened | |
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11.45-12.15 | David Pisetsky (Durham, USA) |
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The role of microparticles in the pathogenesis of inflammatory disease | |
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12.15-12.35 | Edit Buzás (Budapest, Hungary) |
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Extracellular vesicles in inflammation | |
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12.35-12.50 | Zsuzsa Szondy (Debrecen, Hungary) |
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Transglutaminase 2 limits gout arthritis by inhibiting both the monosodium urate-induced proinflammatory response and the removal of apoptotic neutrophils by macrophages at the inflammation site | |
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12.50-13.00 | Group photo |
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13.00-14.00 | Lunch |
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November 8 (Friday) afternoon | |
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Interaction of different cell types in inflammation | |
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Chairs: | László Czirják (Pécs, Hungary),
Lionel Ivashkiv (New York, USA) |
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14.00-14.30 | Hiroshi Takayanagi (Tokyo, Japan) |
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Cell communication in osteoimmunology –
crosstalk between osteocytes and osteoclasts |
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14.30-14.50 | Péter Lakatos (Budapest, Hungary) |
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Molecular targets in pathological bone resorption | |
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14.50-15.05 | Dávid Győri (Budapest, Hungary) |
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The phosphoinositide-3-kinase isoform PI3Kβ regulates osteoclast-mediated bone resorption | |
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15.05-15.20 | Vasileia Ismini Alexaki (Dresden, Germany) |
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NGF: a modulator of microglia-mediated inflammation | |
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15.20-15.35 | Bálint Botz (Pécs, Hungary) |
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Divergent roles of PACAP in nociception and inflammation in the serum transfer arthritis model of the mouse | |
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15.35-16.00 | Coffee break |
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16.00-16.30 | Andrew Luster (Boston, USA) |
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Neutrophil activation and recruitment in inflammatory arthritis | |
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16.30-17.00 | Oliver Distler (Zürich, Switzerland) |
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microRNAs in the pathogenesis of fibrosis | |
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17.00-17.15 | Ádám Dénes (Budapest, Hungary) |
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Infection-induced systemic inflammatory mechanisms mediate inflammation and injury in the brain after cerebral ischaemia | |
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17.15-17.30 | Anna Buday (Budapest, Hungary) |
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Elevated systemic TGF-beta impairs aortic vasomotor function through activation of NADPH oxidase-driven superoxide production and leads to hypertension, myocardial remodeling, and increased plaque formation in apoE(-/-) mice | |
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17.30-17.50 | Pál Géher (Budapest, Hungary) |
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Understanding spondylarthritis: from bedside to the bench (sponsored by MSD) | |
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18.00-21.00 | Poster viewing and buffet dinner |
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November 9 (Saturday) morning | |
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Tyrosine kinases in inflammatory diseases | |
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Chairs: | Gyula Poór (Budapest, Hungary),
Hiroshi Takayanagi (Tokyo, Japan) |
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8.30-8.50 | Zoltán Szekanecz (Debrecen, Hungary) |
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Unmet therapeutic needs in clinical rheumatology | |
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8.50-9.20 | Emese Kiss (Budapest, Hungary) |
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Targeting JAK kinases in human autoimmune diseases (sponsored by Pfizer) | |
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108
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9.20-9.50 | Barbara Walzog (Munich, Germany) |
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The Syk tyrosine kinase pathway in neutrophil migration | |
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9.50-10.05 | Réka Kugyelka (Pécs, Hungary) |
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The effect of ZAP-70 deficiency upon the histological composition of primary- and secondary lymphoid organs in mice | |
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10.05-10.20 | Zoltán Pós (Budapest, Hungary) |
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Genomic scale analysis of the genetic background of interferon alpha responsiveness | |
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10.20-11.00 | Coffee break |
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120
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11.00-11.30 | Clifford Lowell (San Francisco, USA) |
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Negative regulation of autoimmunity and inflammation by the Lyn tyrosine kinase | |
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11.30-11.45 | Tamás Németh (Budapest, Hungary) |
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CARD9 mediates autoantibody-induced autoimmune diseases by linking the Syk tyrosine kinase to cytokine production | |
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126
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11.45-12.00 | Attila Mócsai (Budapest, Hungary) |
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Syk as a therapeutic target in rheumatology: pros, cons, myths and unknowns | |
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12.00-12.15 | Tamas Oravecz (The Woodlands, USA) |
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Genetic and pharmacologic inhibition of Mst1 alters T-cell function and protects against inflammation and autoimmunity | |
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12.15-12.35 | László Kovács (Szeged, Hungary) |
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Methotrexate –old drug, new hopes (sponsored by Sager Pharma) | |
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12.35-13.00 | Poster award ceremony |
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137
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13.00-14.00 | Lunch |
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139
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November 9 (Saturday) afternoon | |
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Other receptors and signaling in inflammation | |
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141
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Chairs: | David Pisetsky (New York, USA) |
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Erzsébet Ligeti (Budapest, Hungary) | |
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143
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144
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14.00-14.30 | Lars Klareskog (Stockholm, Sweden) |
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145
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Genetic and environmental factors determining susceptibility to rheumatoid arthritis | |
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14.30-15.00 | Thomas Pap (Münster, Germany) |
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148
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Intracellular signaling in rheumatoid arthritis synovial fibroblast | |
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15.00-15.15 | Szilvia Benkő (Debrecen, Hungary) |
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Molecular differences of the NLRP3 inflammasome-mediated IL-1β production in LPS- activated human monocyte-derived macrophage subtypes | |
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153
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15.15-15.30 | Timea Csák (Worcester, USA) |
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Both bone marrow-derived and non-bone marrow-derived cells contribute to AIM2 and NLRP3 inflammasome activation in a MyD88-dependent manner in non-alcoholic steatohepatitis | |
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15.30-16.00 | Coffee break |
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158
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16.00-16.30 | Lionel Ivashkiv (New York, USA) |
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Regulation of Inflammatory cytokine production by signaling and epigenetic mechanisms | |
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16.30-16.50 | György Nagy (Budapest, Hungary) |
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162
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The regulation of CD3ζ-chain expression on human T
lymphocytes |
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164
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16.50-17.10 | Tamás Bíró (Debrecen, Hungary) |
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165
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Cannabinoid signaling in cutaneous inflammation | |
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167
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17.10-17.25 | Attila Bácsi (Debrecen, Hungary) |
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168
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TLR ligands up-regulate RIG-I expression in human plasmacytoid dendritic cells in a type I IFN-independent manner | |
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169
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17.25-17.40 | Nandor Than (Grosse Pointe Woods, USA) |
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Novel biomarkers and pathologic pathways of preeclampsia discovered by high-dimensional and systems biology | |
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172
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17.40-18.00 | Concluding remarks and closing of the conference |
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19.00 | Dinner for the invited speakers at the Hungarian Academy of Sciences |