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2: Bell HN, Huber AK, Singhal R, Korimerla N, Rebernick RJ, Kumar R, El-Derany MO, Sajjakulnukit P, Das NK, Kerk SA, Solanki S, James JG, Kim D, Zhang L, Chen B, Mehra R, Frankel TL, Győrffy B, Fearon ER, Pasca di Magliano M, Gonzalez FJ, Banerjee R, Wahl DR, Lyssiotis CA, Green M, Shah YM. Microenvironmental ammonia enhances T cell exhaustion in colorectal cancer. Cell Metab. 2023 Jan 3;35(1):134-149.e6. doi: 10.1016/j.cmet.2022.11.013. Epub 2022 Dec 16. PMID: 36528023.
3: Viganò L, Locatelli A, Ulisse A, Galbardi B, Dugo M, Tosi D, Tacchetti C, Daniele T, Győrffy B, Sica L, Macchini M, Zambetti M, Zambelli S, Bianchini G, Gianni L. Modulation of the Estrogen/erbB2 Receptors Cross-talk by CDK4/6 Inhibition Triggers Sustained Senescence in Estrogen Receptor- and ErbB2-positive Breast Cancer. Clin Cancer Res. 2022 May 13;28(10):2167-2179. doi: 10.1158/1078-0432.CCR-21-3185. PMID: 35254385; PMCID: PMC9595107.
4: Kovács SA, Győrffy B. Transcriptomic datasets of cancer patients treated with immune-checkpoint inhibitors: a systematic review. J Transl Med. 2022 May 31;20(1):249. doi: 10.1186/s12967-022-03409-4. PMID: 35641998; PMCID: PMC9153191.
5: Menyhárt O, Győrffy B, Szabó A. Gyermekkori genetikai rendellenességek diagnosztikája újgenerációs szekvenálással [Diagnosis of genetic disorders in childhood with next-generation sequencing]. Orv Hetil. 2022 Dec 18;163(51):2027-2040. Hungarian. doi: 10.1556/650.2022.32688. PMID: 36528826.
6: Munkácsy G, Santarpia L, Győrffy B. Gene Expression Profiling in Early Breast Cancer-Patient Stratification Based on Molecular and Tumor Microenvironment Features. Biomedicines. 2022 Jan 24;10(2):248. doi: 10.3390/biomedicines10020248. PMID: 35203458; PMCID: PMC8869155.
7: Menyhart O, Weltz B, Győrffy B. MultipleTesting.com: A tool for life science researchers for multiple hypothesis testing correction. PLoS One. 2022 Sep 9;17(9):e0274662. doi: 10.1371/journal.pone.0274662. Erratum for: PLoS One. 2021 Jun 9;16(6):e0245824. PMID: 36084071; PMCID: PMC9462819.
8: Miskey C, Botezatu L, Temiz NA, Gogol-Döring A, Bartha Á, Győrffy B, Largaespada DA, Ivics Z, Sebe A. In Vitro Insertional Mutagenesis Screen Identifies Novel Genes Driving Breast Cancer Metastasis. Mol Cancer Res. 2022 Oct 4;20(10):1502-1515. doi: 10.1158/1541-7786.MCR-21-0772. PMID: 35687718.
9: Ágoston EI, Acs B, Herold Z, Fekete K, Kulka J, Nagy A, Mühl D, Mohacsi R, Dank M, Garay T, Harsanyi L, Győrffy B, Szasz AM. Deconstructing Immune Cell Infiltration in Human Colorectal Cancer: A Systematic Spatiotemporal Evaluation. Genes (Basel). 2022 Mar 25;13(4):589. doi: 10.3390/genes13040589. PMID: 35456394; PMCID: PMC9024576.
10: López-Cade I, García-Barberán V, Cabañas Morafraile E, Díaz-Tejeiro C, Saiz- Ladera C, Sanvicente A, Pérez Segura P, Pandiella A, Győrffy B, Ocaña A. Genomic mapping of copy number variations influencing immune response in breast cancer.Front Oncol. 2022 Sep 1;12:975437. doi: 10.3389/fonc.2022.975437. PMID: 36119512; PMCID: PMC9476651.
11: Pálinkás HL, Pongor L, Balajti M, Nagy Á, Nagy K, Békési A, Bianchini G, Vértessy BG, Győrffy B. Primary Founder Mutations in the <i>PRKDC</i> Gene Increase Tumor Mutation Load in Colorectal Cancer. Int J Mol Sci. 2022 Jan 6;23(2):633. doi: 10.3390/ijms23020633. PMID: 35054819; PMCID: PMC8775830.
12: Dmello C, Sonabend A, Arrieta VA, Zhang DY, Kanojia D, Chen L, Gould A, Zhang J, Kang SJ, Winter J, Horbinski C, Amidei C, Győrffy B, Cordero A, Chang CL, Castro B, Hsu P, Ahmed AU, Lesniak MS, Stupp R, Sonabend AM. Translocon- associated Protein Subunit SSR3 Determines and Predicts Susceptibility to Paclitaxel in Breast Cancer and Glioblastoma. Clin Cancer Res. 2022 Jul 15;28(14):3156-3169. doi: 10.1158/1078-0432.CCR-21-2563. PMID: 35552677.
13: Olah C, Reis H, Hoffmann MJ, Mairinger F, Ting S, Hadaschik B, Krafft U, Grünwald V, Nyirady P, Varadi M, Győrffy B, Kiss A, Szekely E, Sjödahl G, Szarvas T. Predictive value of molecular subtypes and APOBEC3G for adjuvant chemotherapy in urothelial bladder cancer. Cancer Med. 2022 Oct 7. doi: 10.1002/cam4.5324. Epub ahead of print. PMID: 36204983.
14: Alcaraz-Sanabria A, Cabañas Morafraile E, Fernández-Hinojal G, Velasco G, Pérez-Segura P, Pandiella A, Győrffy B, Ocaña A. Transcriptomic Mapping of Non- Small Cell Lung Cancer <i>K-RAS</i> p.G12C Mutated Tumors: Identification of Surfaceome Targets and Immunologic Correlates. Front Immunol. 2022 Feb 1;12:786069. doi: 10.3389/fimmu.2021.786069. PMID: 35178045; PMCID: PMC8843839.
15: Pai P, Wang G, Teo WW, Raez-Rodriguez D, Gabrielson KL, Győrffy B, Downs BM, Aggarwal A, Sukumar S. HOXA5-Mediated Stabilization of IκBα Inhibits the NF-κB Pathway and Suppresses Malignant Transformation of Breast Epithelial Cells. Cancer Res. 2022 Oct 17;82(20):3802 3814. doi: 10.1158/0008-5472.CAN-21-4277. PMID: 36166646; PMCID: PMC9588663.
16: Palassin P, Lapierre M, Bonnet S, Pillaire MJ, Győrffy B, Teyssier C, Jalaguier S, Hoffmann JS, Cavaillès V, Castet-Nicolas A. RIP140 regulates <i>POLK</i> gene expression and the response to alkylating drugs in colon cancer cells. Cancer Drug Resist. 2022 May 7;5(2):401-414. doi: 10.20517/cdr.2021.133. PMID: 35800380; PMCID: PMC9255241.
17: Harrod A, Lai CF, Goldsbrough I, Simmons GM, Oppermans N, Santos DB, Győrffy B, Allsopp RC, Toghill BJ, Balachandran K, Lawson M, Morrow CJ, Surakala M, Carnevalli LS, Zhang P, Guttery DS, Shaw JA, Coombes RC, Buluwela L, Ali S. Genome engineering for estrogen receptor mutations reveals differential responses to anti-estrogens and new prognostic gene signatures for breast cancer. Oncogene. 2022 Oct;41(44):4905-4915. doi: 10.1038/s41388-022-02483-8. Epub 2022 Oct 5. PMID: 36198774; PMCID: PMC7613769.
18: Munkácsy G, Herman P, Győrffy B. Comparison of scientometric achievements at PhD and scientific output ten years later for 4,790 academic researchers. PLoS One. 2022 Jul 27;17(7):e0271218. doi: 10.1371/journal.pone.0271218. PMID: 35895676; PMCID: PMC9328526.
19: Hegedüs L, Livingstone E, Bánkfalvi Á, Viehof J, Enyedi Á, Bilecz Á, Győrffy B, Baranyi M, Tőkés AM, Gil J, Marko-Varga G, Griewank KG, Zimmer L, Váraljai R, Sucker A, Zaremba A, Schadendorf D, Aigner C, Hegedüs B. The Prognostic Relevance of PMCA4 Expression in Melanoma: Gender Specificity and Implications for Immune Checkpoint Inhibition. Int J Mol Sci. 2022 Mar 19;23(6):3324. doi: 10.3390/ijms23063324. PMID: 35328746; PMCID: PMC8949876.
20: Jacquier V, Gitenay D, Fritsch S, Bonnet S, Győrffy B, Jalaguier S, Linares LK, Cavaillès V, Teyssier C. RIP140 inhibits glycolysis-dependent proliferation of breast cancer cells by regulating GLUT3 expression through transcriptional crosstalk between hypoxia induced factor and p53. Cell Mol Life Sci. 2022 May 3;79(5):270. doi: 10.1007/s00018-022-04277-3. PMID: 35501580; PMCID: PMC9061696.
21: Kothalawala WJ, Győrffy B. Transcriptomic and cellular content analysis of colorectal cancer by combining multiple independent cohorts. Clin Transl Gastroenterol. 2022 Jul 20. doi: 10.14309/ctg.0000000000000517. Epub ahead of print. PMID: 35858620.
22: Regan JL, Schumacher D, Staudte S, Steffen A, Lesche R, Toedling J, Jourdan T, Haybaeck J, Golob-Schwarzl N, Mumberg D, Henderson D, Győrffy B, Regenbrecht CRA, Keilholz U, Schäfer R, Lange M. Identification of a neural development gene expression signature in colon cancer stem cells reveals a role for <i>EGR2</i> in tumorigenesis. iScience. 2022 May 31;25(7):104498. doi: 10.1016/j.isci.2022.104498. PMID: 35720265; PMCID: PMC9204726.
23: Ladányi A, Rásó E, Barbai T, Vízkeleti L, Puskás LG, Kovács SA, Győrffy B, Tímár J. Identification of a Tumor Cell Associated Type I IFN Resistance Gene Expression Signature of Human Melanoma, the Components of Which Have a Predictive Potential for Immunotherapy. Int J Mol Sci. 2022 Feb 28;23(5):2704. doi: 10.3390/ijms23052704. PMID: 35269844; PMCID: PMC8911010.
24: Tibor Fekete J, Győrffy B. A unified platform enabling biomarker ranking and validation for 1562 drugs using transcriptomic data of 1250 cancer cell lines. Comput Struct Biotechnol J. 2022 Jun 6;20:2885-2894. doi: 10.1016/j.csbj.2022.06.007. PMID: 35765648; PMCID: PMC9198269.
25: Ding X, Sharko AC, McDermott MSJ, Schools GP, Chumanevich A, Ji H, Li J, Zhang L, Mack ZT, Sikirzhytski V, Shtutman M, Ivers L, O’Donovan N, Crown J, Győrffy B, Chen M, Roninson IB, Broude EV. Inhibition of CDK8/19 Mediator kinase potentiates HER2-targeting drugs and bypasses resistance to these agents in vitro and in vivo. Proc Natl Acad Sci U S A. 2022 Aug 9;119(32):e2201073119. doi: 10.1073/pnas.2201073119. Epub 2022 Aug 1. PMID: 35914167; PMCID: PMC9371674.
26: Olah C, Hahnen C, Nagy N, Musial J, Varadi M, Nyiro G, Gyorffy B, Hadaschik B, Rawitzer J, Ting S, Sjödahl G, Hoffmann MJ, Reis H, Szarvas T. A quantitative polymerase chain reaction based method for molecular subtype classification of urinary bladder cancer-Stromal gene expressions show higher prognostic values than intrinsic tumor genes. Int J Cancer. 2022 Mar 1;150(5):856-867. doi: 10.1002/ijc.33809. Epub 2021 Oct 2. PMID: 34536301.
27: Riecks J, Parnigoni A, Győrffy B, Kiesel L, Passi A, Vigetti D, Götte M. The hyaluronan-related genes HAS2, HYAL1-4, PH20 and HYALP1 are associated with prognosis, cell viability and spheroid formation capacity in ovarian cancer. J Cancer Res Clin Oncol. 2022 Dec;148(12):3399-3419. doi: 10.1007/s00432-022-04127-6. Epub 2022 Jun 29. PMID: 35767191; PMCID: PMC9587083.
28: Mazzeschi M, Sgarzi M, Romaniello D, Gelfo V, Cavallo C, Ambrosi F, Morselli A, Miano C, Laprovitera N, Girone C, Ferracin M, Santi S, Rihawi K, Ardizzoni A, Fiorentino M, D’Uva G, Győrffy B, Palmer R, Lauriola M. The autocrine loop of ALK receptor and ALKAL2 ligand is an actionable target in consensus molecular subtype 1 colon cancer. J Exp Clin Cancer Res. 2022 Mar 29;41(1):113. doi: 10.1186/s13046-022-02309-1. PMID: 35351152; PMCID: PMC8962179.
29: Kahl I, Mense J, Finke C, Boller AL, Lorber C, Győrffy B, Greve B, Götte M, Espinoza-Sánchez NA. The cell cycle-related genes RHAMM, AURKA, TPX2, PLK1, and PLK4 are associated with the poor prognosis of breast cancer patients. J Cell Biochem. 2022 Mar;123(3):581-600. doi: 10.1002/jcb.30205. Epub 2022 Jan 10. PMID: 35014077.
30: Jobbágy A, Kiss N, Meznerics FA, Farkas K, Plázár D, Bozsányi S, Fésűs L, Bartha Á, Szabó E, Lőrincz K, Sárdy M, Wikonkál NM, Szoldán P, Bánvölgyi A. Emergency Use and Efficacy of an Asynchronous Teledermatology System as a Novel Tool for Early Diagnosis of Skin Cancer during the First Wave of COVID-19 Pandemic. Int J Environ Res Public Health. 2022 Feb 25;19(5):2699. doi:10.3390/ijerph19052699. PMID: 35270391; PMCID: PMC8910370.
31: Mahdi M, Hermán L, Réthelyi JM, Bálint BL. Potential Role of the Antidepressants Fluoxetine and Fluvoxamine in the Treatment of COVID 19. Int J Mol Sci. 2022 Mar 30;23(7):3812. doi: 10.3390/ijms23073812. PMID: 35409171; PMCID: PMC8998734.
32: Laczik M, Erdős E, Ozgyin L, Hevessy Z, Csősz É, Kalló G, Nagy T, Barta E, Póliska S, Szatmári I, Bálint BL. Extensive proteome and functional genomic profiling of variability between genetically identical human B-lymphoblastoid cells. Sci Data. 2022 Dec 10;9(1):763. doi: 10.1038/s41597-022-01871-9. PMID: 36496436; PMCID: PMC9741606.
33: Szeitz B, Megyesfalvi Z, Woldmar N, Valkó Z, Schwendenwein A, Bárány N, Paku S, László V, Kiss H, Bugyik E, Lang C, Szász AM, Pizzatti L, Bogos K, Hoda MA, Hoetzenecker K, Marko-Varga G, Horvatovich P, Döme B, Schelch K, Rezeli M. In- depth proteomic analysis reveals unique subtype-specific signatures in human small-cell lung cancer. Clin Transl Med. 2022 Sep;12(9):e1060. doi: 10.1002/ctm2.1060. PMID: 36149789; PMCID: PMC9506422.