Ongoing projects:

  • HCEMM Seeding Group project
    Project title: Cardiac inflammation: a new therapeutic target in myocardial dysfunctions
    2019.05.01 – 2024.04.31.
    Principal investigator: Dr. Zoltán Varga
    Amount of awarded fund (HUF): 125 000 000

  • MTA Research Group support
    Project title: Establishment of a System Pharmacology Research Group: Identification of molecular targets of cardioprotection and hidden cardiotoxicity with functional genomics and molecular network analysis of icchemic heart disease and its comorbidities
    2019.07.01 – 2024.12.31.
    Principal investigator: Prof. Dr. Péter Ferdinandy
    Amount of awarded fund (HUF): 125 000 000

  • 2019-1.1.1-PIACI KFI research grant
    Project title: Development, preclinical and clinical validation of a medical care support device based on artificial intelligence for precision oncology care
    2020.01.01. – 2023.12.31
    Principal investigator: Prof. Dr. Péter Ferdinandy
    Amount of awarded fund (HUF): 78 536 664

  • OTKA FK 134751 research grant
    Project title: New inflammatory mechanisms in the development of heart failure
    2020.12.01. – 2024.11.30
    Principal investigator: Dr. Zoltán Varga
    Amount of awarded fund (HUF): 39 996 000

  • LENDÜLET_2021-38 grant
    Project title: Molecular mechanisms of cardiology and onco-cardiology diseases, as well as their therapeutic and diagnostic studies
    2021.12.01. – 2026.11.30.
    Principal investigator: Dr. Zoltán Varga
    Amount of awarded fund (HUF): 180 002 000

  • FK_21 “OTKA” grant
    Project title: Analysis of bacterial and bile acid abnormalities in the small intestine caused by non-steroidal anti-inflammatory drugs, and investigation of the effect of cannabinoids on enteropathy
    2021.09.01. – 2025.08.31.
    Principal investigator: Dr. Zoltán Zádori
    Amount of awarded fund (HUF): 38 125 000

  • K_21 “OTKA” grant
    Project title: Investigation of hidden cardiotoxicity and cardioprotection in translational cell culture models
    2021.09.01. – 2025.08.31.
    Principal investigator: Dr. Anikó Görbe
    Amount of awarded fund (HUF): 45 983 000

  • K_21 “OTKA” grant
    Project title: Impact of metabolic diseases on extracellular vesicle-based signaling in the cardiovascular system
    2021.09.01. – 2025.08.31.
    Principal investigator: Dr. Zoltán Giricz
    Amount of awarded fund (HUF): 46 960 000

  • FK_21 “OTKA” grant
    Project title: Investigation of the role of the glycinergic system in the development of opioid analgesic tolerance
    2021.09.01. – 2025.08.31.
    Principal investigator: Dr. Ferenc Zádor
    Amount of awarded fund (HUF): 39 942 000

  • Thematic Excellence Program 2021 Therapeutic grant
    Project title: Translational research and innovation in the diagnosis and therapy of ischemic heart disease and its comorbidities
    2021.08.01. – 2025.12.31.
    Principal investigator: Prof. Dr. Péter Ferdinandy
    Amount of awarded fund (HUF): 332 500 000

  • Richter PhD scholarship
    Project title: Identification of new inflammatory mechanisms as therapeutic targets in cardiovascular and metabolic diseases
    2020.09.01 – 2024.08.31.
    Principal investigator: Dr. Tamás Gergely
    Amount of awarded fund (HUF): 3 200 000

  • Richter PhD scholarship
    Project title: The role of extracellular vesicles in cardioprotective therapies
    2020.09.01 – 2024.08.31.
    Principal investigator: Dr. Viktor Nabil Sayour
    Amount of awarded fund (HUF): 3 200 000

  • HCEMM Cardiovascular Comorbidities Research Group
    Project title: Cardiovascular Comorbidities
    2022.01.01 – 2026.12.31.
    Principal investigator: Dr. Nazha Hamdani
    Amount of awarded fund (HUF): 125 000 000

  • Thematic Excellence Program 2021 Therapeutic grant
    Project title: Translational research and innovation in the diagnosis and therapy of ischemic heart disease and its comorbidities
    2021.08.01. – 2025.12.31.
    Principal investigator: Dr. István Gyertyán
    Amount of awarded fund (HUF): 80 000 000 Ft

  • Establishment of National Laboratories and complex development grant
    Project title: National Cardiovascular Laboratory
    2022.03.01 – 2026.02.28.
    Principal investigator: Prof. Dr. Péter Ferdinandy
    Amount of awarded fund (HUF): 1 237 500 000

  • New National Excellence Program
    Project title: Cardio-oncology: Combined use of immune checkpoint inhibitors and PARP inhibitors to potentiate antitumor effects and reduce cardiotoxic side effects
    2022.09.01 – 2023.08.31.
    Principal investigator: Tamás Kovács
    Amount of awarded fund (HUF): 1 200 000

  • New National Excellence Program
    Project title: The role of inflammatory mechanisms in the pathology of heart failure – inflammasome priming and activation in genetic cardiomyopathies
    2022.09.01 – 2023.08.31.
    Principal investigator: Dr. Zsófia Onódi-Gulyás
    Amount of awarded fund (HUF): 2 400 000

  • New National Excellence Program
    Project title: Advantages and limitations of the combined use of angiotensin and opioid receptor ligands in the treatment of chronic pain
    2022.09.01 – 2023.08.31.
    Principal investigator: Dr. Dávid Árpád Karádi
    Amount of awarded fund (HUF): 1 200 000

  • Creation and development of Competence Centers grant
    Project title: The Future Health Industry Competence Center at Semmelweis University
    2023.04.01 – 2027.03.31.
    Principal investigator: Prof. Dr. Péter Ferdinandy
    Amount of awarded fund (HUF): 473 356 490

  • STIA-KFI-2022 grant
    Project title: In vitro testing of promising inflammasome inhibitor active substances for drug repositioning
    2023.01.01 – 2023.12.31.
    Principal investigator: Dr. Zsófia Gulyás-Onódi
    Amount of awarded fund (HUF): 4 864 100

  • STIA-KFI-2022 grant
    Project title: Investigation of the role of the IFITM3 virus restriction protein and its pharmacological influence in heart failure
    2023.01.01 – 2023.12.31.
    Principal investigator: Dr. Viktória Tóth
    Amount of awarded fund (HUF): 5 157 897

  • MTA International Conference Organization grant
    Project title: FAMÉ2023 conference
    2023.01.01 – 2023.12.31.
    Principal investigator: Prof. Dr. Péter Ferdinandy
    Amount of awarded fund (HUF): 525 000

  • Bolyai Scholarship 2023
    Project title: Adrenal steroid hormone synthesis and endoplasmic reticulum (ER)-mitochondria signaling in heart failure after infarction
    2023.09.01 – 2026.08.31.
    Principal investigator: Dr. Gábor Mórotz
    Amount of awarded fund (HUF): 9 000 000

Earlier projects:
 
  • Scientific and Innovative Research Found of Semmelweis University (STIA)
    Project title: Cardiac inflammation – New therapeutic targets in the treatment of heart failure
    2019.02.01 – 2019.12.31.
    Principal investigator: Dr. Zoltán Varga
    Amount of awarded fund (HUF): 9.954.800
  • Semmelweis University Start-up grant
    Project title: Novel inflammatory mechanisms in cardiac dysfunctions
    2018.09.01 – 2020.08.31.
    Principal investigator: Dr. Zoltán Varga
    Amount of awarded fund (HUF): 19.600.000
  • VEKOP_2.3.2-16-2016-00002
    Project title: Exploration the molecular mechanisms of tissue damaging processes
    2017.07.01 – 2021.06.30.
    Principal investigator: Prof. Dr. Péter Ferdinandy
    Amount of awarded fund (HUF): 100.000.000
  • TÉT_16-1-2016-0152
    Project title: Novel therapeutic approaches for aging-induced cardiovascular complications
    2018.02.01 – 2020.01.31.
    Principal investigator: Dr. Zoltán Giricz
    Amount of awarded fund (HUF): 1.880.000
  • NVKP_16-1-2016-0017
    Project title: NVKP National Heart Program – Research and innovation in diagnostics and therapy of ischemic heart disease and heart failure
    2016.12.01 – 2019.11.30.
    Principal investigator: Prof. Dr. Péter Ferdinandy
    Amount of awarded fund (HUF): 485.426.377
  • National Excellence Program – 2017-1.2.1-NKP-2017-00002 NAP2
    Project title: Preclinical validation of potential drug targets in human cognitive disorders
    2017.12.01 – 2020.11.30.
    Principal investigator: Dr. István Gyertyán
    Amount of awarded fund (HUF): 79.998.564
  • New National Excellence Program (ÚNKP)
    Project title: The role of inflammasome activation in end-stage heart failure
    2018.09.01 – 2019.06.30.
    Principal investigator: Dr. Zsófia Gulyás-Onódi
    Amount of awarded fund (HUF): 1.000.000
  • New National Excellence Program (ÚNKP)
    Project title: Novel high efficacy opioids and the investigation of their supraspinal, spinal and peripheral effects in neuropathic pain models
    2018.09.01 – 2019.06.30.
    Principal investigator: Dr. Mihály Balogh
    Amount of awarded fund (HUF): 3.000.000
  • New National Excellence Program (ÚNKP)
    Project title: Neuropeptides in cardioprotection
    2018.09.01 – 2019.06.30.
    Principal investigator: Dr. Éva Sághy
    Amount of awarded fund (HUF): 3.000.000
  • Higher Education Institutional Excellence Program (FIKP)
    Project title: Development for therapeutic purposes
    2018.04.01 – 2019.06.30.
    Principal investigator: Prof. Dr. Péter Ferdinandy
    Amount of awarded fund (HUF): 68.778.000
  • Higher Education Institutional Excellence Program (FIKP)
    Project title: Neurology thematic programme
    2018.04.01 – 2019.06.30.
    Principal investigator: Dr. Tibor Zelles, Dr. László Köles
    Amount of awarded fund (HUF): 24.999.999
  • Scientific and Innovative Research Found of Semmelweis University (STIA)
    Project title: Leica LMD6 laser microdissection device
    2018.11.06 – 2019.11.30.
    Principal investigator: Prof. Dr. Péter Ferdinandy
    Amount of awarded fund (HUF): 49.516.030
  • Scientific and Innovative Research Found of Semmelweis University (STIA)
    Project title: Dual function Laser Speckle Contrast Imager
    2018.11.06 – 2019.11.30.
    Principal investigator: Dr. Zoltán Zádori
    Amount of awarded fund (HUF): 20.104.193
  • Scientific and Innovative Research Found of Semmelweis University (STIA)
    Project title: Purchase “CYTONOTE 6 Wells” Tool for High Throughput Automated Testing of Tissue Damaging Processes
    2019.02.06 – 2019.12.31.
    Principal investigator: Dr. Anikó Görbe
    Amount of awarded fund (HUF): 5.949.600
  • Scientific and Innovative Research Found of Semmelweis University (STIA)
    Project title: Supplementing the equipment list of the Hungarian central Extracellular Vesicle Research, Service and Reference Laboratory with a chromatograph
    2019.02.06 – 2019.12.31.
    Principal investigator: Dr. Zoltán Giricz
    Amount of awarded fund (HUF): 9.951.732
  • National Research, Development and Innovation Office of Hungary (NKFI) FK 124878
    Project title: Analysing the role of COX-2 and alpha2-adrenoceptors in NSAID-induced small intestinal injury and dysbiosis
    2017.09.01 – 2021.08.31.
    Principal investigator: Dr. Zoltán Zádori
    Amount of awarded fund (HUF): 37.164.000 
  • National Research, Development and Innovation Office of Hungary (NKFI) NN 126968
    Project title: Novel butyrylcholinesterase reactivators for pseudo-catalytic scavenging of organophosphates (BChER)
    2017.10.01 – 2019.12.31.
    Principal investigator: Dr. Huba Kalász
    Amount of awarded fund (HUF): 26.999.000
  • National Research, Development and Innovation Office of Hungary (NKFI) KF 128875
    Project title: Purinergic calcium signaling in the supporting cells of the organ of Corti, its role in hearing and noise-induced hearing loss
    2018.11.01 – 2022.10.31.
    Principal investigator: Dr. Tibor Zelles
    Amount of awarded fund (HUF): 47.994.000
  • National Research, Development and Innovation Office of Hungary (NKFI) KH 125570
    Project title: Identification of drug targets for ischemic heart disease and its comorbidities by bioinformatic target prediction based on transcriptomic data followed by experimental validaton of predicted targets
    2017.10.01 – 2019.09.30.
    Principal investigator: Prof. Dr. Péter Ferdinandy
    Amount of awarded fund (HUF): 19.670.000
  • Dean’s OTKA Support
    Project title: Research of extracellular vesicles is metabolic co-morbidities of cardiovascular diseases
    2018.11.22 – 2019.05.31.
    Principal investigator: Dr. Zoltán Giricz
    Amount of awarded fund (HUF): 500.000
  • Dean’s OTKA Support
    Project title: Investigation of endogenous cardioprotective mechanisms in the presence of cardiovascular comorbidities and their co-medications using innovative cell culture models.
    2018.11.22 – 2019.05.31.
    Principal investigator: Dr. Anikó Görbe
    Amount of awarded fund (HUF): 500.000
  • Dean’s OTKA Support
    Project title: Investigation of the role of dipeptidyl-peptidase 4 inhibitors and short CART peptide fragments in spinal nociceptive transmission
    2018.11.22 – 2019.05.31.
    Principal investigator: Dr. Kornél Király
    Amount of awarded fund (HUF): 500.000
  • Dean’s OTKA Support
    Project title: Hearing and hearing loss: purinergic signaling and noise-induced hearing loss
    2018.11.22 – 2019.05.31.
    Principal investigator: Dr. Tibor Zelles
    Amount of awarded fund (HUF): 500.000
  • TÉT_16-1-2016-0057
    Project title: Mechanisms of immunmodulation in exosome-mediated cardioprotection
    2017.01.01 – 2018.12.31.
    Principal investigator: Dr. Zoltán Giricz
    Amount of awarded fund (HUF): 1.906.000
  • New National Excellence Program (ÚNKP)
    Project title: Analysing the role of COX-2 in NSAID-induced enteropathy and dysbiosis
    2017.09.01 – 2018.06.30.
    Principal investigator: Dr. Zoltán Zádori
    Amount of awarded fund (HUF): 1.400.000
  • New National Excellence Program (ÚNKP)
    Project title: Identifying novel therapeutic strategies in post-infarction heart failure: the role of neutrophil cell death
    2018.09.01 – 2019.01.31.
    Principal investigator: Dr. Gábor Koncsos
    Amount of awarded fund (HUF): 1.500.000
  • Scientific and Innovative Research Found of Semmelweis University (STIA)
    Project title: Infrastructure Development of the Translational Hearing Laboratory – Expansion of Clinical, Industrial and Academic Relationships
    2017.11.02 – 2018.11.30.
    Principal investigator: Dr. Tibor Zelles
    Amount of awarded fund (HUF): 10.380.146
  • Scientific and Innovative Research Found of Semmelweis University (STIA)
    Project title: The effect of non-steroidal antiinflammatory drugs on the bile acid metabolome
    2017.11.02 – 2018.11.30.
    Principal investigator: Dr. Zoltán Zádori
    Amount of awarded fund (HUF): 4.709.490
  • Scientific and Innovative Research Found of Semmelweis University (STIA)
    Project title: A renin-angiotenzin rendszer szerepe a neurodegeneratív és pszichiátriai kórképek patomechanizmusában – új terápiás célpontok azonosítása
    2017.11.02 – 2018.11.30.
    Principal investigator: Dr. László Köles
    Amount of awarded fund (HUF): 5.250.000
  • Scientific and Innovative Research Found of Semmelweis University (STIA)
    Project title: The effect of spinally administered dipeptidyl-peptidase 4 inhibitors on inflammatory thermal hyperalgesia
    2017.11.02 – 2018.11.30.
    Principal investigator: Dr. Kornél Király
    Amount of awarded fund (HUF): 5.992.112
  • Scientific and Innovative Research Found of Semmelweis University (STIA)
    Project title: Development of IT and e-education at the Department of Pharmacology and Pharmacotherapy of Semmelweis University
    2017.11.02 – 2018.11.30.
    Principal investigator: Dr. Pál Riba
    Amount of awarded fund (HUF): 7.671.473
  • KTIA_NAP_13-2-2017-0001
    Project title: Procurement of a multifunctional automated modular cognitive test system
    2017.03.01 – 2018.11.30.
    Principal investigator: Dr. István Gyertyán
    Amount of awarded fund (HUF): 33.974.532
  • Richter Centenáriumi Alapítvány Research Grant
    Project title: Behavioral pharmacology of novel high efficacy opioids with limited central penetration
    2017.09.01 – 2018.06.30.
    Principal investigator: Dr. Mihály Balogh
    Amount of awarded fund (HUF): 1.344.000
  • 2017/K/10/1479
    Project title: Pharmacological treatment of repeated, moderate noise exposure evoked hearing loss
    2017.10.01 – 2018.09.30.
    Principal investigator: Judit Szepesy
    Amount of awarded fund (HUF): 1.300.000
  • New National Excellence Program (ÚNKP)
    Project title: Investigation of peptides modulating neurotransmission in the auditory pathway in genetically modified mice
    2016.09.01 – 2017.06.30.
    Principal investigator: Viktória Humli
    Amount of awarded fund (HUF): 2.500.000
  • OTKA PD 109051 project
    Project title: Role of exosomes and microvesicles in cardiac stress adaptation
    01.09.2013. – 31.08.2016.
    Project leader: Dr. Zoltán Giricz
    Támogatás összege: 13.186 M HUF
  • OTKA K 109737 project
    Projekt title: Cardiac stress adaptation in obesity: the role of autophagy and mitophagy
    2013.09.01 – 2017.09.01.
    Consortium leader: Prof. Ferdinandy Péter
    Project grant: 21.000 M Ft
  • NIH(NKTH)-ANR(French) bilateral TET project (TET_10-1-2011-0421)
    Project title: Hearing and deafness: molecular mechanisms and therapeutic approaches
    01.01.2012. – 31.12.2014.
    Consortium leader: Prof. Szilveszter E. Vizi
    Hungarian project leader: Dr. Tibor Zelles
    French partner: Prof. Christine Petit (Institut Pasteur, Paris)
    Project grant: 90 M HUF
  • EFSD New Horizons Collaborative Research Initiative project
    Project title: Targeting autophagy and mitophagy to restore  diabetes-induced loss of cardiac stress adaptation
    01.06.2013. – 31.05.2015.
    Project leader: Peter Ferdinandy
    Participants: Rainer Schulz, Kerstin Böngler, Zoltan Giricz, Zoltan Varga
    Project grant: 99,000 EUR
  • OTKA-FWF project
    Project title Identification miRNAs of therapeutic and diagnostic value in endogenous cardioprotection by postconditioning in a clinically relevant swine model of myocardial infarction
    01.06.2013 – 31.05.2016.
    Project leader: Peter Ferdinandy
    Participants: Mariann Gyongyosi-Pavone, Edit Buzas, Zoltan Giricz, Zoltan Varga
    Project grant 32.76 M HUF
  • OTKA PD 109602 project
    Project title: Imidazoline 1 receptor – sphingosine 1-phosphate interaction in the gut : novel targets for the therapy of colonic inflammation?
    01.09.2013. – 31.08.2016.
    Project leader: Dr. Zoltán Zádori
    Project grant: 10.920 M HUF
  • OTKA K100155 project
    Project title: Blood-brain-barrier penetration of organic compounds
    01.01.2012. – 31.01.2015.
    Project leader: Prof. Kalász Huba
    Project grant: 18.393 M HUF
  • OMAA project
    Project title: Autophagy in cardioprotection (Autophagie in der Kardioprotektion)
    01.02.2014. – 31.01.2015.
    Project leader: Dr. Zoltán Giricz
    Project grant: 1.616 M HUF
  • OMAA project
    Project title: α2- adrenoceptors and imidazoline I1-receptors in the NSAID-induced small intestinal ulcers (α2- Adrenozeptoren und Imidazolin I1-Rezeptoren in NSAR-induzierten Dünnarm-Ulzera)
    01.07.2014. – 30.06.2015.
    Project leader: Prof. Klára Gyires
    Project grant: 1.931 M HUF