Ongoing projects:
-
HCEMM Seeding Group project
Project title: Cardiac inflammation: a new therapeutic target in myocardial dysfunctions
2019.05.01 – 2024.04.31.
Principal investigator: Dr. Zoltán Varga
Amount of awarded fund (HUF): 125 000 000 -
MTA Research Group support
Project title: Establishment of a System Pharmacology Research Group: Identification of molecular targets of cardioprotection and hidden cardiotoxicity with functional genomics and molecular network analysis of icchemic heart disease and its comorbidities
2019.07.01 – 2024.12.31.
Principal investigator: Prof. Dr. Péter Ferdinandy
Amount of awarded fund (HUF): 125 000 000 -
2019-1.1.1-PIACI KFI research grant
Project title: Development, preclinical and clinical validation of a medical care support device based on artificial intelligence for precision oncology care
2020.01.01. – 2023.12.31
Principal investigator: Prof. Dr. Péter Ferdinandy
Amount of awarded fund (HUF): 78 536 664 -
OTKA FK 134751 research grant
Project title: New inflammatory mechanisms in the development of heart failure
2020.12.01. – 2024.11.30
Principal investigator: Dr. Zoltán Varga
Amount of awarded fund (HUF): 39 996 000 -
LENDÜLET_2021-38 grant
Project title: Molecular mechanisms of cardiology and onco-cardiology diseases, as well as their therapeutic and diagnostic studies
2021.12.01. – 2026.11.30.
Principal investigator: Dr. Zoltán Varga
Amount of awarded fund (HUF): 180 002 000 -
FK_21 “OTKA” grant
Project title: Analysis of bacterial and bile acid abnormalities in the small intestine caused by non-steroidal anti-inflammatory drugs, and investigation of the effect of cannabinoids on enteropathy
2021.09.01. – 2025.08.31.
Principal investigator: Dr. Zoltán Zádori
Amount of awarded fund (HUF): 38 125 000 -
K_21 “OTKA” grant
Project title: Investigation of hidden cardiotoxicity and cardioprotection in translational cell culture models
2021.09.01. – 2025.08.31.
Principal investigator: Dr. Anikó Görbe
Amount of awarded fund (HUF): 45 983 000 -
K_21 “OTKA” grant
Project title: Impact of metabolic diseases on extracellular vesicle-based signaling in the cardiovascular system
2021.09.01. – 2025.08.31.
Principal investigator: Dr. Zoltán Giricz
Amount of awarded fund (HUF): 46 960 000 -
FK_21 “OTKA” grant
Project title: Investigation of the role of the glycinergic system in the development of opioid analgesic tolerance
2021.09.01. – 2025.08.31.
Principal investigator: Dr. Ferenc Zádor
Amount of awarded fund (HUF): 39 942 000 -
Thematic Excellence Program 2021 Therapeutic grant
Project title: Translational research and innovation in the diagnosis and therapy of ischemic heart disease and its comorbidities
2021.08.01. – 2025.12.31.
Principal investigator: Prof. Dr. Péter Ferdinandy
Amount of awarded fund (HUF): 332 500 000 -
Richter PhD scholarship
Project title: Identification of new inflammatory mechanisms as therapeutic targets in cardiovascular and metabolic diseases
2020.09.01 – 2024.08.31.
Principal investigator: Dr. Tamás Gergely
Amount of awarded fund (HUF): 3 200 000 -
Richter PhD scholarship
Project title: The role of extracellular vesicles in cardioprotective therapies
2020.09.01 – 2024.08.31.
Principal investigator: Dr. Viktor Nabil Sayour
Amount of awarded fund (HUF): 3 200 000 -
HCEMM Cardiovascular Comorbidities Research Group
Project title: Cardiovascular Comorbidities
2022.01.01 – 2026.12.31.
Principal investigator: Dr. Nazha Hamdani
Amount of awarded fund (HUF): 125 000 000 -
Thematic Excellence Program 2021 Therapeutic grant
Project title: Translational research and innovation in the diagnosis and therapy of ischemic heart disease and its comorbidities
2021.08.01. – 2025.12.31.
Principal investigator: Dr. István Gyertyán
Amount of awarded fund (HUF): 80 000 000 Ft -
Establishment of National Laboratories and complex development grant
Project title: National Cardiovascular Laboratory
2022.03.01 – 2026.02.28.
Principal investigator: Prof. Dr. Péter Ferdinandy
Amount of awarded fund (HUF): 1 237 500 000 -
New National Excellence Program
Project title: Cardio-oncology: Combined use of immune checkpoint inhibitors and PARP inhibitors to potentiate antitumor effects and reduce cardiotoxic side effects
2022.09.01 – 2023.08.31.
Principal investigator: Tamás Kovács
Amount of awarded fund (HUF): 1 200 000 -
New National Excellence Program
Project title: The role of inflammatory mechanisms in the pathology of heart failure – inflammasome priming and activation in genetic cardiomyopathies
2022.09.01 – 2023.08.31.
Principal investigator: Dr. Zsófia Onódi-Gulyás
Amount of awarded fund (HUF): 2 400 000 -
New National Excellence Program
Project title: Advantages and limitations of the combined use of angiotensin and opioid receptor ligands in the treatment of chronic pain
2022.09.01 – 2023.08.31.
Principal investigator: Dr. Dávid Árpád Karádi
Amount of awarded fund (HUF): 1 200 000 -
Creation and development of Competence Centers grant
Project title: The Future Health Industry Competence Center at Semmelweis University
2023.04.01 – 2027.03.31.
Principal investigator: Prof. Dr. Péter Ferdinandy
Amount of awarded fund (HUF): 473 356 490 -
STIA-KFI-2022 grant
Project title: In vitro testing of promising inflammasome inhibitor active substances for drug repositioning
2023.01.01 – 2023.12.31.
Principal investigator: Dr. Zsófia Gulyás-Onódi
Amount of awarded fund (HUF): 4 864 100 -
STIA-KFI-2022 grant
Project title: Investigation of the role of the IFITM3 virus restriction protein and its pharmacological influence in heart failure
2023.01.01 – 2023.12.31.
Principal investigator: Dr. Viktória Tóth
Amount of awarded fund (HUF): 5 157 897 -
MTA International Conference Organization grant
Project title: FAMÉ2023 conference
2023.01.01 – 2023.12.31.
Principal investigator: Prof. Dr. Péter Ferdinandy
Amount of awarded fund (HUF): 525 000 -
Bolyai Scholarship 2023
Project title: Adrenal steroid hormone synthesis and endoplasmic reticulum (ER)-mitochondria signaling in heart failure after infarction
2023.09.01 – 2026.08.31.
Principal investigator: Dr. Gábor Mórotz
Amount of awarded fund (HUF): 9 000 000
- Scientific and Innovative Research Found of Semmelweis University (STIA)
Project title: Cardiac inflammation – New therapeutic targets in the treatment of heart failure
2019.02.01 – 2019.12.31.
Principal investigator: Dr. Zoltán Varga
Amount of awarded fund (HUF): 9.954.800 - Semmelweis University Start-up grant
Project title: Novel inflammatory mechanisms in cardiac dysfunctions
2018.09.01 – 2020.08.31.
Principal investigator: Dr. Zoltán Varga
Amount of awarded fund (HUF): 19.600.000 - VEKOP_2.3.2-16-2016-00002
Project title: Exploration the molecular mechanisms of tissue damaging processes
2017.07.01 – 2021.06.30.
Principal investigator: Prof. Dr. Péter Ferdinandy
Amount of awarded fund (HUF): 100.000.000 - TÉT_16-1-2016-0152
Project title: Novel therapeutic approaches for aging-induced cardiovascular complications
2018.02.01 – 2020.01.31.
Principal investigator: Dr. Zoltán Giricz
Amount of awarded fund (HUF): 1.880.000 - NVKP_16-1-2016-0017
Project title: NVKP National Heart Program – Research and innovation in diagnostics and therapy of ischemic heart disease and heart failure
2016.12.01 – 2019.11.30.
Principal investigator: Prof. Dr. Péter Ferdinandy
Amount of awarded fund (HUF): 485.426.377 - National Excellence Program – 2017-1.2.1-NKP-2017-00002 NAP2
Project title: Preclinical validation of potential drug targets in human cognitive disorders
2017.12.01 – 2020.11.30.
Principal investigator: Dr. István Gyertyán
Amount of awarded fund (HUF): 79.998.564 - New National Excellence Program (ÚNKP)
Project title: The role of inflammasome activation in end-stage heart failure
2018.09.01 – 2019.06.30.
Principal investigator: Dr. Zsófia Gulyás-Onódi
Amount of awarded fund (HUF): 1.000.000 - New National Excellence Program (ÚNKP)
Project title: Novel high efficacy opioids and the investigation of their supraspinal, spinal and peripheral effects in neuropathic pain models
2018.09.01 – 2019.06.30.
Principal investigator: Dr. Mihály Balogh
Amount of awarded fund (HUF): 3.000.000 - New National Excellence Program (ÚNKP)
Project title: Neuropeptides in cardioprotection
2018.09.01 – 2019.06.30.
Principal investigator: Dr. Éva Sághy
Amount of awarded fund (HUF): 3.000.000 - Higher Education Institutional Excellence Program (FIKP)
Project title: Development for therapeutic purposes
2018.04.01 – 2019.06.30.
Principal investigator: Prof. Dr. Péter Ferdinandy
Amount of awarded fund (HUF): 68.778.000 - Higher Education Institutional Excellence Program (FIKP)
Project title: Neurology thematic programme
2018.04.01 – 2019.06.30.
Principal investigator: Dr. Tibor Zelles, Dr. László Köles
Amount of awarded fund (HUF): 24.999.999 - Scientific and Innovative Research Found of Semmelweis University (STIA)
Project title: Leica LMD6 laser microdissection device
2018.11.06 – 2019.11.30.
Principal investigator: Prof. Dr. Péter Ferdinandy
Amount of awarded fund (HUF): 49.516.030 - Scientific and Innovative Research Found of Semmelweis University (STIA)
Project title: Dual function Laser Speckle Contrast Imager
2018.11.06 – 2019.11.30.
Principal investigator: Dr. Zoltán Zádori
Amount of awarded fund (HUF): 20.104.193 - Scientific and Innovative Research Found of Semmelweis University (STIA)
Project title: Purchase “CYTONOTE 6 Wells” Tool for High Throughput Automated Testing of Tissue Damaging Processes
2019.02.06 – 2019.12.31.
Principal investigator: Dr. Anikó Görbe
Amount of awarded fund (HUF): 5.949.600 - Scientific and Innovative Research Found of Semmelweis University (STIA)
Project title: Supplementing the equipment list of the Hungarian central Extracellular Vesicle Research, Service and Reference Laboratory with a chromatograph
2019.02.06 – 2019.12.31.
Principal investigator: Dr. Zoltán Giricz
Amount of awarded fund (HUF): 9.951.732 - National Research, Development and Innovation Office of Hungary (NKFI) FK 124878
Project title: Analysing the role of COX-2 and alpha2-adrenoceptors in NSAID-induced small intestinal injury and dysbiosis
2017.09.01 – 2021.08.31.
Principal investigator: Dr. Zoltán Zádori
Amount of awarded fund (HUF): 37.164.000 - National Research, Development and Innovation Office of Hungary (NKFI) NN 126968
Project title: Novel butyrylcholinesterase reactivators for pseudo-catalytic scavenging of organophosphates (BChER)
2017.10.01 – 2019.12.31.
Principal investigator: Dr. Huba Kalász
Amount of awarded fund (HUF): 26.999.000 - National Research, Development and Innovation Office of Hungary (NKFI) KF 128875
Project title: Purinergic calcium signaling in the supporting cells of the organ of Corti, its role in hearing and noise-induced hearing loss
2018.11.01 – 2022.10.31.
Principal investigator: Dr. Tibor Zelles
Amount of awarded fund (HUF): 47.994.000 - National Research, Development and Innovation Office of Hungary (NKFI) KH 125570
Project title: Identification of drug targets for ischemic heart disease and its comorbidities by bioinformatic target prediction based on transcriptomic data followed by experimental validaton of predicted targets
2017.10.01 – 2019.09.30.
Principal investigator: Prof. Dr. Péter Ferdinandy
Amount of awarded fund (HUF): 19.670.000 - Dean’s OTKA Support
Project title: Research of extracellular vesicles is metabolic co-morbidities of cardiovascular diseases
2018.11.22 – 2019.05.31.
Principal investigator: Dr. Zoltán Giricz
Amount of awarded fund (HUF): 500.000 - Dean’s OTKA Support
Project title: Investigation of endogenous cardioprotective mechanisms in the presence of cardiovascular comorbidities and their co-medications using innovative cell culture models.
2018.11.22 – 2019.05.31.
Principal investigator: Dr. Anikó Görbe
Amount of awarded fund (HUF): 500.000 - Dean’s OTKA Support
Project title: Investigation of the role of dipeptidyl-peptidase 4 inhibitors and short CART peptide fragments in spinal nociceptive transmission
2018.11.22 – 2019.05.31.
Principal investigator: Dr. Kornél Király
Amount of awarded fund (HUF): 500.000 - Dean’s OTKA Support
Project title: Hearing and hearing loss: purinergic signaling and noise-induced hearing loss
2018.11.22 – 2019.05.31.
Principal investigator: Dr. Tibor Zelles
Amount of awarded fund (HUF): 500.000 - TÉT_16-1-2016-0057
Project title: Mechanisms of immunmodulation in exosome-mediated cardioprotection
2017.01.01 – 2018.12.31.
Principal investigator: Dr. Zoltán Giricz
Amount of awarded fund (HUF): 1.906.000 - New National Excellence Program (ÚNKP)
Project title: Analysing the role of COX-2 in NSAID-induced enteropathy and dysbiosis
2017.09.01 – 2018.06.30.
Principal investigator: Dr. Zoltán Zádori
Amount of awarded fund (HUF): 1.400.000 - New National Excellence Program (ÚNKP)
Project title: Identifying novel therapeutic strategies in post-infarction heart failure: the role of neutrophil cell death
2018.09.01 – 2019.01.31.
Principal investigator: Dr. Gábor Koncsos
Amount of awarded fund (HUF): 1.500.000 - Scientific and Innovative Research Found of Semmelweis University (STIA)
Project title: Infrastructure Development of the Translational Hearing Laboratory – Expansion of Clinical, Industrial and Academic Relationships
2017.11.02 – 2018.11.30.
Principal investigator: Dr. Tibor Zelles
Amount of awarded fund (HUF): 10.380.146 - Scientific and Innovative Research Found of Semmelweis University (STIA)
Project title: The effect of non-steroidal antiinflammatory drugs on the bile acid metabolome
2017.11.02 – 2018.11.30.
Principal investigator: Dr. Zoltán Zádori
Amount of awarded fund (HUF): 4.709.490 - Scientific and Innovative Research Found of Semmelweis University (STIA)
Project title: A renin-angiotenzin rendszer szerepe a neurodegeneratív és pszichiátriai kórképek patomechanizmusában – új terápiás célpontok azonosítása
2017.11.02 – 2018.11.30.
Principal investigator: Dr. László Köles
Amount of awarded fund (HUF): 5.250.000 - Scientific and Innovative Research Found of Semmelweis University (STIA)
Project title: The effect of spinally administered dipeptidyl-peptidase 4 inhibitors on inflammatory thermal hyperalgesia
2017.11.02 – 2018.11.30.
Principal investigator: Dr. Kornél Király
Amount of awarded fund (HUF): 5.992.112 - Scientific and Innovative Research Found of Semmelweis University (STIA)
Project title: Development of IT and e-education at the Department of Pharmacology and Pharmacotherapy of Semmelweis University
2017.11.02 – 2018.11.30.
Principal investigator: Dr. Pál Riba
Amount of awarded fund (HUF): 7.671.473 - KTIA_NAP_13-2-2017-0001
Project title: Procurement of a multifunctional automated modular cognitive test system
2017.03.01 – 2018.11.30.
Principal investigator: Dr. István Gyertyán
Amount of awarded fund (HUF): 33.974.532 - Richter Centenáriumi Alapítvány Research Grant
Project title: Behavioral pharmacology of novel high efficacy opioids with limited central penetration
2017.09.01 – 2018.06.30.
Principal investigator: Dr. Mihály Balogh
Amount of awarded fund (HUF): 1.344.000 - 2017/K/10/1479
Project title: Pharmacological treatment of repeated, moderate noise exposure evoked hearing loss
2017.10.01 – 2018.09.30.
Principal investigator: Judit Szepesy
Amount of awarded fund (HUF): 1.300.000 - New National Excellence Program (ÚNKP)
Project title: Investigation of peptides modulating neurotransmission in the auditory pathway in genetically modified mice
2016.09.01 – 2017.06.30.
Principal investigator: Viktória Humli
Amount of awarded fund (HUF): 2.500.000 - OTKA PD 109051 project
Project title: Role of exosomes and microvesicles in cardiac stress adaptation
01.09.2013. – 31.08.2016.
Project leader: Dr. Zoltán Giricz
Támogatás összege: 13.186 M HUF - OTKA K 109737 project
Projekt title: Cardiac stress adaptation in obesity: the role of autophagy and mitophagy
2013.09.01 – 2017.09.01.
Consortium leader: Prof. Ferdinandy Péter
Project grant: 21.000 M Ft - NIH(NKTH)-ANR(French) bilateral TET project (TET_10-1-2011-0421)
Project title: Hearing and deafness: molecular mechanisms and therapeutic approaches
01.01.2012. – 31.12.2014.
Consortium leader: Prof. Szilveszter E. Vizi
Hungarian project leader: Dr. Tibor Zelles
French partner: Prof. Christine Petit (Institut Pasteur, Paris)
Project grant: 90 M HUF - EFSD New Horizons Collaborative Research Initiative project
Project title: Targeting autophagy and mitophagy to restore diabetes-induced loss of cardiac stress adaptation
01.06.2013. – 31.05.2015.
Project leader: Peter Ferdinandy
Participants: Rainer Schulz, Kerstin Böngler, Zoltan Giricz, Zoltan Varga
Project grant: 99,000 EUR - OTKA-FWF project
Project title Identification miRNAs of therapeutic and diagnostic value in endogenous cardioprotection by postconditioning in a clinically relevant swine model of myocardial infarction
01.06.2013 – 31.05.2016.
Project leader: Peter Ferdinandy
Participants: Mariann Gyongyosi-Pavone, Edit Buzas, Zoltan Giricz, Zoltan Varga
Project grant 32.76 M HUF - OTKA PD 109602 project
Project title: Imidazoline 1 receptor – sphingosine 1-phosphate interaction in the gut : novel targets for the therapy of colonic inflammation?
01.09.2013. – 31.08.2016.
Project leader: Dr. Zoltán Zádori
Project grant: 10.920 M HUF - OTKA K100155 project
Project title: Blood-brain-barrier penetration of organic compounds
01.01.2012. – 31.01.2015.
Project leader: Prof. Kalász Huba
Project grant: 18.393 M HUF - OMAA project
Project title: Autophagy in cardioprotection (Autophagie in der Kardioprotektion)
01.02.2014. – 31.01.2015.
Project leader: Dr. Zoltán Giricz
Project grant: 1.616 M HUF - OMAA project
Project title: α2- adrenoceptors and imidazoline I1-receptors in the NSAID-induced small intestinal ulcers (α2- Adrenozeptoren und Imidazolin I1-Rezeptoren in NSAR-induzierten Dünnarm-Ulzera)
01.07.2014. – 30.06.2015.
Project leader: Prof. Klára Gyires
Project grant: 1.931 M HUF