Unlike traditional fluorescence microscopy, Leica’s Thunder Imager module allows us to:

  • Optimal imaging of large slice thickness samples by software removal of out-of-focus light

  • maximize the signal-to-noise ratio of the imaging system, thus providing the detail required for further image analysis

  • provide near confocal microscopic quality images, but in a faster and simpler way

Our microscope can now be used not only for conventional fluorescence microscopy and laser microdissection, but also for fast and easy acquisition of near-confocal microscopy-quality images.

Image of a section from mouse kidney
before and after running the background removal algorithm.

The upgrade of the fluorescence microscope was supported by the Project no. RRF-2.3.1-21-2022-00003, which has been implemented with the support provided by the European Union.