Dear Students,
The Juhász-Nagy Sándor Scientific Research Laboratory of the Városmajor Heart and Vascular Center at Semmelweis University offers the opportunity to participate in the Student Research Society (TDK). We are looking for committed and motivated students in their 2nd to 4th year who are interested in cardiology, cardiac surgery, experimental sciences, and translational medicine.
Our research group’s profile and areas of research include:
· Investigation of the development of the “athlete’s heart” in small animal models;
· Investigation of the development and treatment of heart failure in small animal models and human biobank samples, as well as the translation of preclinical findings into other clinical research projects at the Clinic (e.g., projects related to TAVI and CRT therapies);
· Monitoring of the hemodynamic effects of pseudoallergy induced by experimental drugs in large animal models;
· Optimization of donor organ preservation in rat and canine heart transplantation models;
· Investigation of the effects of different drugs on the aorta in mouse models of connective tissue diseases (vascular Ehlers-Danlos syndrome, Marfan syndrome);
· All of this is carried out with the help of an extensive network of research collaborations both within and beyond the university (Freiburg, Halle, Heidelberg, King’s College London).
During your TDK work, you will have the opportunity to learn and master numerous modern
· in vivo methods (e.g., small animal echocardiography, pressure-volume analysis, electrophysiology, assisting in small and large animal surgeries);
· ex vivo methods (vascular physiology studies in an organ bath);
· in vitro methods (e.g., PCR, Western blot, ELISA, histological staining, immunohistochemistry, immunofluorescence, proteomic sample preparation);
· in silico methods (omics data analysis, laboratory automation, analysis of digitized histological slides).
· In addition to experimental work, participation in clinical research is also possible.
Preferred applicants are those who:
· Possess in-depth knowledge of the relevant basic subjects (e.g., physiology, biostatistics),
· Are willing and able to work independently and responsibly,
· Are open to acquiring and optimizing new experimental methods,
· Have at least an intermediate level of English proficiency.
To apply, please send your CV and a short motivational letter to the following email addresses: sevszekjnstkl@gmail.com and radovitstamas@yahoo.com
Best regards, Prof. Dr. Tamás Radovits, University Professor, and his Research Group