Summary

Quantitative and medical biochemistry
36 h lectures and 15 h seminar/practical classes
Tutor: Prof Krasimir Kolev, MD, PhD, DSc

The Biochemistry course offers a concise overview of the dynamic metabolic networks in the cell focusing on the general principles of enzyme kinetics, structure and control of metabolic pathways. Aspects essential for future specialists in Biotechnology are emphasized: modern biochemical techniques in the characterization of intermolecular interactions and enzyme action, in silico modelling of biochemical processes and systems. Medical orientation is implemented with discussion of the molecular basis of selected diseases with major public health impact (cardiovascular, neurodegenerative diseases) focusing on the molecular targets of therapy. Students participate in formal lectures, tutorials and computer-simulated practical lessons.

Recommended literature

Orvosi Biokémia – Egyetemi tankönyv, Szerkesztette: Ádám Veronika, Semmelweis Kiadó, Budapest 2016

Athel Cornish-Bowden: Fundamentals of enzyme kinetics. Wiley-Blackwell, Weinheim, 2012

Thomas M. Devlin: Textbook of biochemistry with clinical correlations. Wiley-Liss, New York, 2012

David Fell: Understanding the control of metabolism. Portland Press, London, 2003