Head of Core Facility
György Tibor Balogh Prof. Dr.
István Mándity Dr.
Core Facility Address
Department of Pharmaceutical Chemistry
H-1092 Budapest,
Hőgyes Endre u. 7-9.
Contact E-mail
chiral.medchem@semmelweis.hu
Staff
5
Quality Control
ISO9001
What we offer
- Separation of chiral molecule isomers (diastereomers or enantiomers) and optimalization of experimental design and conditions.
- Chiral enantioseparation using HPLC or CE methods, optionally using cyclodextrin binding as chiral separator.
- Docking studies, CD/FI measurements and NMR/UV titrimetry to characterize cyclodextrin complexation.
Why work with us
In our core facility enantioseparation using reverse-phase chiral columns is a reliable and versatile tool for chiral analysis in polar organic mode. The use of cyclodextrins as a tool for separation provides an efficient means of rapid method optimalization complemented with binding characterization.
Our equipment
- Agilent 1260 HPLC system with DAD detector
- Agilent 7100 CE system with DAD detector
- JASCO HPLC with ELSD detector
- Waters HPLC-MS system
- More than 20 chiral HPLC columns
- Jasco UV-VIS spectrophotometer
- Jasco j815 CD spectrometer (CD/UV/FI parallel measurement)