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Cikkek

2019

  • Engineering tyrosine residues into hemoglobin enhances heme reduction, decreases oxidative stress and increases vascular retention of a hemoglobin based blood substitute
    Chris E.Cooper, Gary G. A. Silkstone, Michelle Simons, Badri Rajagopal, Natalie Syrett, Thoufieq Shaik, Svetlana Gretton, Elizabeth Welbourn, Leif Bülow, Nélida Leiva Eriksson,  Luca Ronda, Andrea Mozzarelli, Andras Eke, Domokos Mathe, Brandon J.Reeder
    Free Radical Biology and Medicine, 2019 Apr, 134, 106-118.

  • Virtual museum of congenital heart defects: digitization and establishment of a database for cardiac specimens
    Laszló Király, Bálint Király, Krisztián Szigeti, Csaba Zsolt Tamás, Sándor Darányi
    Quantitative Imaging in Medicine and Surgery, 2019 Jan, 9(1), 115-126.

2018

  • Multimodal PET/MRI Imaging Results Enable Monitoring the Side Effects of Radiation Therapy
    N Kovács, K Szigeti, N Hegedűs, I Horváth, DS Veres, M Bachmann, R Bergmann D Máthé

    Contrast Media and Molecular Imaging, 2018 Nov.

  • Improved Conjugation, 64-Cu Radiolabeling, in Vivo Stability, and Imaging Using Nonprotected Bifunctional Macrocyclic Ligands: Bis(Phosphinate) Cyclam (BPC) Chelators
    T David, V Hlinová, V KubíčekR BergmanStrieseN BerndtD SzöllősiT  KovácsMáthéM BachmannHJ Pietzsch, P Hermann
    Journal of medicinal chemistry, 2018 Sep, 61(19), 8774-8796. 
  • Novel radiomics evaluation of bone formation utilizing multimodal (SPECT/X-ray CT) in vivo imaging
    F Budán, K Szigeti, M Weszl, I Horváth, E Balogh, R Kanaan, K Berényi, Zs Lacza, D Máthé, Z Gyöngyi
    PloS one, 2018 Sep13(9), e0204423. 

  • Selegiline reduces adiposity induced by high-fat, high-sucrose diet in male rats
    CT Nagy, G Koncsos, Z Varga, T Baranyai, S Tuza, F Kassai, AJ Ernyey, I Gyertyán, K Király, A Oláh, T Radovits, B Merkely, N Bukosza, G Szénási, P Hamar, D Máthé, K Szigeti, C Pelyhe, M Jelemensky, Z Onódi, Zs Helyes, R Schulz, Z Giricz, P Ferdinandy 
    British Journal of Farmacology, 2018 Jul, 175(18): 3712-3726. 

  • Evaluation of Brain Nuclear Medicine Imaging Tracers in a Murine Model of Sepsis-Associated Encephalopathy 
    D Szöllősi, N Hegedűs, DS Veres, I Futó, I Horváth, N Kovács, B Martinecz, Á Dénes, D Seifert, R Bergmann, O Lebeda, Z Varga, Z Kaleta, K Szigeti, D Máthé
    Molecular Imaging and Biology, 2018 May, 1-11. Online available. doi: 10.1007/s11307-018-1201-3.

  • Thallium labeled citrate-coated Prussian blue nanoparticles as potential imaging agent
    K Szigeti, N Hegedűs, K Rácz, I Horváth, DS Veres, D Szöllősi, I Futó, K Módos, T Bozó, K Karlinger, N Kovács, Z Varga, M Babos, F Budán, P Padmanabhan, B Gulyás, D Máthé

    Contrast Media and Molecular Imaging, 2018 Apr.

  • Dissimilar flexibility of α and β subunits of human adult hemoglobin influences the protein dynamics and its alteration induced by allosteric effectors
    G Schay, A.D. Kaposi, L. Smeller, K Szigeti, J Fidy, L Herényi

    PloS one13(3), e0194994. 

  • Age-dependent changes at the blood-brain barrier. A Comparative structural and functional  study in young adult and middle aged rats
    L Bors, K Tóth, E Zsófia Tóth, Á Bajza, A Csorba, K Szigeti, D Máthé, G Perlaki, G Orsi, G K. Tóth, F Erdő

    Brain Research Bulletin, 2018 Mar, 139: 269-277.

2017

  • Functional shift with maintained regenerative potential following portal vein ligation
    T Kovács, D Máthé, A Fülöp, K Jemnitz, A Bátai-Konczos, Zs Veres, Gy Török, DS Veres, I Horváth, K Szigeti, L Homolya, A Szijártó

    Scientific Reports, 2017 Dec, 7(1): 18065. Online available. doi: 10.1038/s41598-017-18309-7

  • Direct immobilization of manganese chelates on silica nanospheres for MRI applications
    M Pálmai, A Pethő, L Naszályi Nagy, Sz Klébert, Z May, J Mihály, A Wacha, K Jemnitz, Zs Veres, I Horváth, K Szigeti, D Máthé, Z Varga

    Journal of Colloid and Interface Science, 2017 Jul, 498: 298-305. 

  • Comparative erythrocyte deformability investigations by filtrometry, slit-flow and rotational ektacytometry in a long-term follow-up animal study on splenectomy and different spleen preserving operative techniques: Partial or subtotal spleen resection and spleen autotransplantation
    Miko I, Nemeth N, Sogor V, Kiss F, Toth E, Peto K, Furka A, Vanyolos E, Toth L, Varga J, Szigeti K, Benkő I, Olah AV, Furka I, 

    Clinical Hemorheology Microcirculation, 2017 Jan, 66(1): 83-96. 

  • State of the art in vivo imaging techniques for laboratory animals
    DT Lauber, A Fülöp, T Kovács, K Szigeti, D Máthé, A Szijártó

    Laboratory Animals, 2017 Jan, 51(5):465-478. 

2016

  • Influence of barium sulfate X-ray imaging contrast material on properties of floating drug delivery tablets
    P Diós, K Szigeti, F Budán, M Pócsik, DS Veres, D Máthé, S Pál, A Dévay, S Nagy

    European Journal of Pharmaceutical Science, 2016 Sep, 95:46-53. 

  • Diastolic dysfunction in prediabetic male rats: role of mitochondrial oxidative stress
    G Koncsos, Z Varga, T Baranyai, K Boengler, S Rohrbach, L Li, K-D Schluter, R Schreckenberg, T Radovits, A OláhCs Mátyás, Á Lux, M Al-Khrasani, T Komlódi, N Bukosza, D Máthé, L Deres, M Barteková, T Rajtík, A AdameováK Szigeti, P Hamar, Zs Helyes, L Tretter, P Pacher, B Merkely, Z Giricz, R Schulz, P Ferdinandy
    American Journal of Physiology – Heart and Circulatory Physiology, 2016 Okt, 311(4): H927-H943. 
  • Radiolabeling of Extracellular Vesicles with 99mTc for Quantitative In Vivo Imaging Studies
    Z Varga, I Gyurkó, K Pálóczi, E Buzás, I Horváth, N Hegedűs, D Máthé, K Szigeti

    Cancer Biotherapy and Radiopharmaceuticals, 2016 Jun, 31(5): 168-73. 
  • Production and in vivo imaging of 203Pb as a surrogate isotope for in vivo 212Pb internal absorbed dose studies
    D Máthé, K Szigeti, N Hegedűs, I Horváth, DS Veres, B Kovács, Z Szűcs

    Applied Radiation and Isotopes, 2016 Aug, 114: 1-6. 

  • Radiomics-based differentiation of lung disease models generated by polluted air based on X-ray computed tomography data
    K Szigeti, T Szabó, C Korom, I Czibak, I Horváth, DS Veres, Z Gyöngyi, K Karlinger, R Bergmann, M Pócsik, F Budán, D Máthé

    BMC Medical Imaging, 2016 Feb; 16(1): 14. 

  • Synthesis, characterization, and application of core-shell Co0.16Fe2.84O4@NaYF4(Yb, Er) and Fe3O4@NaYF4(Yb, Tm) nanoparticle as trimodal (MRI, PET/SPECT, and optical) imaging agents
    X Cui, D Máthé, N Kovács, I Horváth, M Jauregui-Osoro, RTM de Rosales, GED Mullen, W Wilson, Y Yong, D Krüger, AN Khlobystov, M Gimenez-Lopez, M Semjéni, K Szigeti, DS Veres, H Lu, I Hernández, WP Gillin, A Protti, K Kis Petik, MA Green, PJ Blower

    Bioconjugate Chemistry, 2016 Feb; 27(2): 319-28. 

2015

  • Al(OH)3 facilitated synthesis of water-soluble, magnetic, radiolabelled and fluorescent hydroxyapatite nanoparticles
    X Cui, MA Green, PJ Blower, D Zhou, Y Yan, W Zhang, K Djanashvili, D Máthé, DS Veres, K Szigeti
    Chemical Communications, 2015 June; 51(45): 9332–9335. 
  • A novel SPECT-based approach reveals early mechanisms of central and peripheral inflammation after cerebral ischemia
    K Szigeti, I Horváth, DS Veres, B Martinecz, N Lénárt, N Kovács, E Bakcsa, A Márta, M Semjéni, D Máthé, Á Dénes
    Journal of Cerebral Blood Flow & Metabolism, 2015 Dec; 35(12): 1921-9. 
  • Preformulation studies and optimization of sodium alginate based floating drug delivery system for eradication of Helicobacter pylori
    P Diós, S Nagy, S Pál, T Pernecker, B Kocsis, F Budán, I Horváth, K Szigeti, K Bölcskei, D Máthé, A Dévay
    European Journal of Pharmaceutics and Biopharmaceutics, 2015 Oct; 96: 196-206. 

2014

  • The role of molecular imaging in modern drug development
    L Cunha, K Szigeti, D Máthé, LF Metello
    Drug Discovery Today, 2014 Jul; 19(7): 936-48. 
  • Preclinical imaging: an essential ally in modern biosciences
    L Cunha, I Horváth, S Ferreira, J Lemos, P Costa, D Vieira, DS Veres, K Szigeti, T Summavielle, D Máthé, LF Metello
    Molecular Diagnosis & Therapy, 2014 Apr; 18(2): 153-73. 
  • Demonstration of metabolic and cellular effects of portal vein ligation using multi modal PET/MRI measurements in healthy rat liver
    A Fülöp, A Szijártó, L Harsányi, A Budai, D Pekli, D Korsós, I Horváth, N Kovács, K Karlinger, D Máthé, K Szigeti

    PLoS ONE, 2014 Mar; 9(3): e90760. 
  • Aluminium hydroxide stabilised MnFe2O4 and Fe3O4 nanoparticles as dual-modality contrasts agent for MRI and PET imaging
    X Cui, S Belo, D Krüger, Y Yan, RTM de Rosales, M Jauregui-Osoro, H Ye, S Su, D Máthé, N Kovács, I Horváth, M Semjéni, K Sunassee, K Szigeti, MA Green, PJ Blower

    Biomaterials, 2014 Jul; 35(22): 5840-6. 
  • Motion based X-ray imaging modality
    K Szigeti, D Máthé, S Osváth

    Medical Imaging, IEEE Transactions, 2014 Oct; 33(10): 2031-8. 
  • Differential regulatory role of pituitary adenylate-cyclase activating polypeptide in the serum-transfer-induced arthritis model
    B Botz, K Bölcskei, L Kereskai, M Kovács, T Németh, K Szigeti, I Horváth, D Máthé, N Kovács, H Hashimoto, D Reglődi, J Szolcsányi, E Pintér, A Mócsai, Zs Helyes

    Arthritis & Rheumatology, 2014 Oct; 66(10): 2739-50. 
  • Longitudinal in vivo MR imaging of live earthworms
    F Budán, N Kovács, P Engelmann, I Horváth, DS Veres, P Németh, K Szigeti, D Máthé

    Journal of Experimental Zoology Part A: Ecological Genetics and Physiology, 2014 Nov; 321(9): 479-89. 
  • Quantitative liver lesion volume determination by nanoparticle-based SPECT
    DS Veres, D Máthé, I Futó, I Horváth, Á Balázs, K Karlinger, K Szigeti

    Molecular Imaging and Biology. 2014 Apr; 16(2): 167-72. 

2013

  • In vivo SPECT and ex vivo autoradiographic brain imaging of the novel selective CB1 receptor antagonist radioligand [125I]SD7015 in CB1 knock-out and wildtype mouse
    D Máthé, I Horváth, K Szigeti, SR Donohue, VW Pike, Z Jia, C Ledent, M Palkovits, TF Freund, C Haldin, B Gulyás

    Brain Research Bulletin, 2013 Feb; 91: 46-51. 
  • Kombinált molekuláris képalkotó módszerek és a személyre szabott orvoslás
    K Szigeti
    IME Képalkotó Diagnosztikai Különszám, 2013 Okt; 12: 29-32.

2012

  • [125I]SD-7015 reveals fine modalities of CB1 cannabinoid receptor density in the prefrontal cortex during progression of Alzheimer’s disease
    Sz Farkas, K Nagy, M Palkovits, GG Kovács, Z Jia, S Donohue, V Pike, C Halldin, D Máthé, T Harkany, B Gulyás, L Csiba

    Neurochemistry International, 2012 Feb; 60(3): 286-91. 
  • Compromised bone healing following spacer removal in a rat femoral defect model
    G Skaliczki, M Weszl, K Schandl, T Major, M Kovács, J Skaliczki, H Redl, M Szendrői, K Szigeti, D Máthé, Cs Dobó-Nagy, Zs Lacza

    Acta Physiologica Hungarica, 2012 Jun; 99(2): 223-32. 
  • The decrease of dopamine D2/D3 receptor densities in the putamen and nucleus caudatus goes parallel with maintained levels of CB1 cannabinoid receptors in Parkinson’s disease: A preliminary autoradiographic study with the selective dopamine D2/D3 antagonist [3H]raclopride and the novel CB1 inverse agonist [125I]SD7015
    Sz Farkas, K Nagy, Z Jia, T Harkany, M Palkovits, SR Donohou, VW Pike, C Halldin, D Máthé, L Csiba, B Gulyás

    Brain Research Bulletin, 2012 Apr 10; 87(6): 504–510. 
  • Noninvasive molecular imaging of neuroinflammation
    AH Jacobs, B Tavitian and the INMiND consortium

    Journal of Cerebral Blood Flow & Metabolism, 2012 Jul; 32(7): 1393-415. 
  • Systematic evaluation of 99mTc-tetrofosmin versus 99mTc-sestamibi to study murine myocardial perfusion in small animal SPECT/CT
    A Vrachimis, S Hermann, D Máthé, O Schober, M Schäfers
    EJNMMI Research, 2012 May;2(1):21.