Number of meta-analyses: 3

Project Description:

Caner’s main area of interest is intensive care medicine. He is working on a systematic review and meta-analysis on the effects of preoperative steroid administration on intra- and postoperative outcomes in liver surgery patients who undergo liver surgery suffer from high rates of postoperative complications in which dysregulation immune response of the host plays a major role. In a systematic review, he aims to summarize the evidence on the use of hemadsorption therapy for patients with acute liver dysfunction. Randomized trials are lacking, hence in this systematic review, he aims to collect, analyze and report on all aspects of the current knowledge on hemadsorption therapy in this context. Lastly, in a meta-analysis, he aims to compare the effects of goal-directed fluid therapy (GDFT) versus conventional management on postoperative complications after major liver surgery.