Number of meta-analyses: 1

Number of clinical trials: 1

Project Description:

Dorina is a newly graduated medical doctor and her interest is in the pediatric field. Her first project is a systematic review and meta-analysis on the effect of preoperative anti-TNF-alpha therapy on postoperative complications in pediatric irritable bowel disease. Concern was raised that by modulating the immune response, anti-TNF-alpha may increase surgical site infections and morbidity. The result of the meta-analysis will help the physician in operation schedules. Her second project is a registry analysis about intestinal resections in pediatric Crohn’s disease. It is a nationwide survey based on the Hungarian Pediatric IBD Registry. The aim of this multicenter, retrospective cohort study is to analyze the surgical interventions among Hungarian children with IBD based on HUPIR. They would like to assess the rate of surgical interventions after diagnosis, identify predictor factors for the first surgery, and prognostic factors that increase the rate of postoperative complications and recurrences.