EM Medical Genetics and Immunology I

Credits

3 credits

Course structure

Lectures and practical sessions are held every week.

Lectures

One lecture per week (90 minutes).

Lecture time

Friday, 8:00–9:30, NET (Green Lecture Hall)

Practical sessions

One practical session per week, 75 minutes. Students must attend their Neptun-assigned group; make-up attendance in another group is not permitted.

Holiday

Friday, 23 October 2026

Prerequisite subject

Macroscopic Anatomy and Developmental Biology II; Medical Biochemistry I

Requirement

Minimum requirement

Attendance at practical sessions

At least 75%

Genetics midterms

Minimum 50% in each of the two midterms separately

Practical session attendance

Students must attend classes in their own Neptun-assigned group. Attendance in another group is not permitted, and missed practical sessions cannot be made up in a different group.

Minimum attendance requirement

Students are required to attend at least 75% of practical sessions.

Attendance registration

Attendance at practical sessions is registered weekly by the instructor.

Total absences per semester

A maximum of 3 absences per semester is allowed, regardless of the reason.

Late arrivals

Two late arrivals of up to 10 minutes count as 1 absence.
A single delay of more than 20 minutes counts as 1 absence.

Responsibility for absences

Students are responsible for keeping track of their own absences. The instructor will provide a summary of absences only at the end of the semester.

Consequence

More than 3 absences invalidate the semester.

Midterm schedule

8th and 13th teaching weeks, at the time and place of the practical sessions, with personal attendance

Test format

Written test, 40 points, 40 minutes, completed on paper.

Test content

Topics from the lectures and practical sessions preceding the midterm, as specified under the “Midterm” tab in Moodle: textbook material (text and figures) and the provided PDF study materials.

No rescheduling or improvement

Midterms cannot be postponed and results cannot be improved.

Results

Results are available on the online Moodle platform and are also posted in Neptun. E-mails asking about results will not receive a response.

Requirement for signature

The result of each midterm must be ≥50%.

Bonus

Average of the two midterms ≥80% and QR-code-confirmed attendance at at least 7 lectures → offered colloquium grade of 4 (Good).

Average of the two midterms ≥90% and QR-code-confirmed attendance at at least 7 lectures → offered colloquium grade of 5 (Excellent).

Missed midterm

If a student is unable to attend a midterm for a legitimate reason, the absence must be justified to the practical instructor within one week.

Make-up midterms will be held in weeks 10 and 14 at times outside the regular timetable; students will be notified via Neptun.

Make-up for a failed midterm

If a student scores below 50% on a midterm, a make-up midterm will be held in week 10 or at the end of the semester, as applicable. A maximum of two repeat attempts is allowed. (TVSZ §29 (2)) The make-up date will be announced via Neptun.

Genetics textbook

Cs. Szalai (ed.): Medical Genetics and Genomics, e-book, 2022

Lecture and practical presentations

Moodle, personal notes

Exam format

Written exam via Moodle during the exam period

Duration: 50 minutes, 60 points. At least 50% required to pass.

Exam period

According to the Academic Calendar.

Exam dates

Published in Neptun one month before the start of the exam period.

Registration

Exclusively through Neptun.

Identity verification

According to the University Study and Examination Rules, students must prove their identity with an official photo ID (passport, student card). Photos shown on a phone are not accepted. If identity cannot be verified, a “did not appear” status is recorded in Neptun; the exam opportunity is not lost, but an exam administration fee must be paid as specified in the applicable University regulations. (TVSZ §34 (8))

Exam content

The examination covers the topics taught in lectures and practical sessions, as well as the textbook material specified in the syllabus (see the Moodle). In addition to knowledge of the course material, students are expected to synthesize and integrate their knowledge. When studying, students should remember that the examinable material includes not only the text of the textbook and lectures but also figures and diagrams.

Results

Published in Neptun within 48 hours. E-mail inquiries regarding comprehensive examination results will not receive a response.

Retake examination

Two retake opportunities.

Failed retake examination

In accordance with the Semmelweis University Study and Examination Regulations (TVSZ), the third examination attempt must be taken before an examination committee. For this course, the third attempt is conducted as an oral examination.

Unexcused absence

One exam opportunity is lost.

Justification of absence

An absence supported by a valid reason must be justified to the course coordinator within 3 business days, in person, in writing, electronically, or through an authorized representative.

If the student adequately justifies the absence, the “did not appear” entry will be deleted. (TVSZ §34 (10))

Lectures

Friday 8:00-9:30, NET Selye (Green) Hall 

Practices

Monday-Friday

Week 1

(Sept 7-11)

Introduction to human genetics 

Mitosis and mitotic errors

Week 2

(Sept 14-18)

Cytogenetics

Meiosis and meiotic errors

Week 3

(Sept 21-25)

Genetic variations 

Cytogenetics I

Week 4

(Sept 28 – Oct 2)

Epigenetics

Cytogenetics II

Week 5

(Oct 5-9)

Monogenic inheritance I

Pedigree analysis

Week 6

(Oct 12-16)

Role of sex in inheritance 

Diagnostic genetic testing

Week 7

(Oct 20-23)

Oct 23 Holiday

Holiday

Autosomal inheritance AD/AR

Week 8

(Oct 26-30)

Complex inheritance

Population genetics 

Midterm I

Week 9

(Nov 2-6)

Oncogenetics

Sex-linked inheritance

Week 10

(Nov 9-13)

Genome and environment,

Evolution genetics

Complex inheritance

Week 11

(Nov 16-20)

Introduction to genomics

Genetic screening

Oncogenetics

Week 12

(Nov 23-27)

Genetic therapy

Gametogenesis, prenatal genetic testing

Week 13

(Nov 30 – Dec 4)

Pharmacogenomics 

Midterm II

Week 14

(Dec 7-11) 

Nutrigenomics

From genes to bedside