SEMMELWEIS UNIVERSITY, SECOND DEPARTMENT OF PAEDIATRICS
TOPIC
Pediatrics – Oncology and Hematology
VISION
Achieve the best therapeutic response/effect with the lowest possible toxicity when using chemotherapeutic agents (e.g. pharmacokinetic modifications).
MISSION
Prevent severe toxicity of chemotherapeutics in pediatric malignancies.
SPECIFIC GOALS
- PROJECT 1: Comparison of toxicity levels between bolus injection and continuous vincristine infusion in patients with malignancies: a systematic review and meta-analysis.
- PROJECT 2: Comparison of pharmacokinetic parameters and toxicity levels between bolus injection and continuous vincristine infusion in children with hematologic malignancies: protocol and pilot of a prospective randomised trial.