Lysosome-related organelles (LROs) are a group of cell type-specific subcellular compartments with unique composition, morphology and structure that share numerous features with lysosomes and that function in varied processes such as pigmentation, hemostasis, lung plasticity and immunity.
Caenorhabditis elegans LROs are the site of concentration of vital dyes such as Nile red as well as age-associated anthranilate autofluorescence.
In this project, we aim to characterize the importance of LRO autofluorescent material accumulation in C. elegans stress tolerance.
Head: Hajdú Gábor