A fundamental attribute of living organisms is the continuous adaptation to environmental change (stress). What kind of mechanisms maintain physiological homeostasis and links to nervous system? How can our inner balance altered, resulting in somatic and neurodegenerative diseases?
To decipher these questions, we investigate various aspects of cytoprotective responses such as stress, detoxification and immune responses. Moreover, we also focus on how adaptation response is altered with aging and various pathological conditions such as stress tolerance, metabolism, learning and memory formation in the model organism Caenorhabditis elegans as well as bioinformatics and network analysis.
Our research will increase our understanding of adaptive responses, age-related decline and may open new therapeutic avenues of promoting robust, extended health.