International Workshop on Precision Antibiotic Therapy  

Semmelweis University is pleased to announce a three-day, hands-on international workshop focusing on the implementation of precision antibiotic therapy using nonparametric pharmacokinetic (PK) modeling and simulation. 

This intensive course provides practical training in R using the Pmetrics™ package and demonstrates how model-informed precision dosing can support clinical decision-making through BestDose™. 

 

Date: 23-25 April 2026 

Location: Semmelweis University, Budapest, Hungary Nagyvárad tér Theoretical Building (NET) 1st Floor, Room L2 

 
Participation fee: 
On-site participation: 360 EUR
Online participation: 300 EUR

You will receive information about payment options by email after registration. 

 

About the Workshop 

Precision antibiotic therapy is becoming an essential component of modern clinical pharmacology and infectious disease management. This workshop offers a structured and practice-oriented introduction to: 

  • Nonparametric pharmacokinetic modeling 
  • Monte Carlo simulation for PK/PD target attainment 
  • Model-informed precision dosing 
  • Clinical implementation of therapeutic drug monitoring (TDM) 
  • Individualized dose optimization using BestDose™ 

Participants will work directly with real modeling workflows and gain practical implementation strategies applicable in both clinical and research environments. 

 

Who Should Attend 

This workshop is recommended for: 

  • Clinicians and trainees involved in antibiotic therapy (infectious diseases, intensive care, internal medicine) 
  • Clinical pharmacologists and hospital pharmacists 
  • TDM and laboratory professionals supporting dosing decisions 
  • Researchers and analysts interested in PK/PD and pharmacometrics 

 

What Participants Will Gain 

By the end of the workshop, participants will be able to: 

  • Understand the clinical value of nonparametric PK models in individualized dosing 
  • Build and interpret nonparametric PK models in R using Pmetrics™ 
  • Perform Monte Carlo simulations to evaluate microbial PK/PD target attainment 
  • Apply BestDose™ principles for individualized dose prediction and optimization 
  • Develop a practical pathway for implementing precision antibiotic therapy in clinical or research settings 

Program Overview 
Day 1 
Nonparametric pharmacokinetic modeling using R and Pmetrics™ 
  • Introduction to pharmacometrics 
  • Introduction to Pmetrics™ 
  • Model fitting and evaluation 
  • Plotting and validation of PK models 
  • Hands-on modeling exercises 
Day 2 
Clinical implementation & Monte Carlo simulations 
  • Role of the TDM laboratory 
  • Nonparametric Monte Carlo simulations 
  • PK/PD target attainment evaluation 
  • Translation of parametric to nonparametric models 
  • Hands-on exercises 
Day 3 
Precision pharmacotherapy & BestDose™ 
  • Optimal sampling strategies 
  • Artificial quasi-models 
  • Dose optimization using BestDose™ 
  • Case-based applications 
  • Preanalytical, analytical and postanalytical aspects of antibiotic TDM 
  • Discussion and wrap-up 
 

 

Lecturers 

The workshop features internationally recognized experts in pharmacometrics and precision dosing: 

  • Professor Michael N. Neely, MD, MSc, FCP 
    Chief, Division of Infectious Diseases, Children’s Hospital Los Angeles 
    University of Southern California, USA 
  • Professor Sylvain Goutelle, PharmD, PhD 
    Université Claude Bernard Lyon 1, France 
  • Markus Hovd, PharmD, PhD 
    University of Oslo, Norway 
  • Julian David Otalvaro, MSc, PhD 
    University of Southern California, USA 
    Universidad de Antioquía, Colombia 
  • Dr. Gellért Balázs Karvaly, PharmD, PhD 
    Semmelweis University, Budapest, Hungary 

 

Practical Information 

  • Location: Semmelweis University, Budapest, Hungary Nagyvárad tér Theoretical Building (NET) 1st Floor, Room L2 
  • Date: 23-25 April 2026
  • Certificate of participation will be provided. 
  • For more information, refer to our workshop catalogue
Registration
You will receive information about payment options by email after registration.