SEMMELWEIS UNIVERSITY, SECOND DEPARTMENT OF PAEDIATRICS
Number of meta-analyses: 1
Number of clinical trials: 1
Project Description:
Dóra is a newly-graduated medical doctor and her research area is pediatric hematology and oncology. She is working on a systematic review and meta-analysis, comparing the toxicity levels between bolus injection and long-term vincristine infusion in patients with malignancies. Previously it has been shown that different chemotherapeutic agents have the same effectiveness when administered in long-term infusions but may have fewer side effects. The results of her study could help in the reduction of vincristine toxicity. Her second project is a clinical trial with the same question as in her meta-analysis. There is a lack of data regarding the comparison of bolus injection and long-term vincristine infusion. She aims to evaluate the severity of adverse events in two different routes (bolus injection vs. 180 min infusion) of vincristine-sulfate administration in children with hematologic malignancies.