SEMMELWEIS UNIVERSITY, SECOND DEPARTMENT OF PAEDIATRICS

TOPIC

Pediatrics – Oncology and Hematology

VISION

Achieve the best therapeutic response/effect with the lowest possible toxicity when using chemotherapeutic agents (e.g. pharmacokinetic modifications).

MISSION

Prevent severe toxicity of chemotherapeutics in pediatric malignancies.

SPECIFIC GOALS
  • PROJECT 1: Comparison of toxicity levels between bolus injection and continuous vincristine infusion in patients with malignancies: a systematic review and meta-analysis.
  • PROJECT 2: Comparison of pharmacokinetic parameters and toxicity levels between bolus injection and continuous vincristine infusion in children with hematologic malignancies: protocol and pilot of a prospective randomised trial.

Progress Reports