Auf Englisch:
Several researchers at Semmelweis University participated in the study led by Dr. Bence György and Dr. Botond Roska, which aims to prevent vision loss in patients suffering from a form of inherited macular degeneration. The newly developed gene-editing technique could lead to breakthroughs not only in the treatment of Stargardt disease but also in the therapy of other hereditary retinal diseases. Semmelweis University has been collaborating with world-renowned Semmelweis alumnus Dr. Botond Roska and his institute, the Institute of Molecular and Clinical Ophthalmology Basel (IOB) for more than ten years, whose mission is to cure vision loss and restore eyesight.
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“In probing the newly published base-editing technique in human models, i.e. human retinal cultures artificially fixed in the laboratory, we have tested the IOB-developed viral vectors in several combinations to measure their effectiveness. The fact that the tests were done in real human tissues provides strong evidence for the future applicability of the treatment in patients,” stressed Dr. Arnold Szabó, Head of the Retina Laboratory at the Department of Anatomy, Histology and Embryology at Semmelweis University. He added that Dániel Magda and Ferenc Kilin, who also co-authored the study, had carried out much of the experimental work.
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Semmelweis University involved in testing breakthrough technology to prevent vision loss