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About the 2nd Department of Pathology

Address
H-1091 Budapest, Üllői út 93.
Tel: (+36-1) 215-69-21; 215-7300, ext. 53400
Fax: (+36-1) 215-6921
Email: titkarsag.pat2@med.semmelweis-univ.hu 

Head of Department
Prof. András Kiss, M.D., Ph.D., D.Sc.

Background
The 2nd Department of Pathology dates back to 1894; its first director was Ottó Pertik (1895-1913). It was at the Department that Ödön Krompecher described basal cell carcinoma, the most common type of malignant disease, which came to be referred to as the Krompecher tumour all around the world. The 2nd Department of Pathology has shared its building with the Department of Forensic Medicine since 1948.

Education
Pathology is taught to third-year medical students in Hungarian, English, and German. For two semesters, the students have lectures in pathology for 60 hours, and attend autopsy and histopathology courses for 120 hours. Higher grade students take part in the activities of the Students’ Scientific Association. The Department participates in the resident program of Semmelweis University, supporting the training of future specialists in pathology.

Research
Prof. Dr. József Tímár
Using genomic techniques, we have identified new melanoma specific markers, such as P2X7, RyR2, endonexin, CB1receptor and CD44 splice-pattern, with the latter seeming to show adequate specificity.

Prof. Dr. Zsuzsa Schaff
We have conducted studies on the factors influencing development of chronic liver diseases, including liver carcinomas. Emphasis was placed on the role of cell junction alterations detected during liver fibro- and carcinogenesis, with special attention paid to studies on the claudin family forming the backbone of tight junctions (TJ).

Prof. Dr. Janina Kulka
We have performed studies on cell junction molecules in human tumours as well as in tumours of other species, examining the characteristics of claudins and cadherins, as cell junction molecules, in primary breast and prostate tumours. 

Running Fellowships

  • New prognostic and diagnostic markers in primer and metastatic liver tumors (OTKA 101435; closing date: 31-12-2015);
  • Development of biomarker platform and the affectivity of cervical biomarkers in multicentre clinic examination (KMR 12-12012-0032, closing date: 31-12-2014).

Impact Factors
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Health Services
Surgical Biopsy Laboratory
Immunohistochemical Laboratory
Cytopathology Laboratory
Molecular Pathology Diagnostics
Postmortem Unit