Head of Core Facility
György Tibor Balogh Prof. Dr.
István Mándity Dr.
Core Facility Address
Department of Pharmaceutical Chemistry
H-1092 Budapest,
Hőgyes Endre u. 7-9.
Contact E-mail
ex-vivo.medchem@semmelweis.hu
Staff
5
Quality Control
ISO9001
What we offer
- Ex vivo penetration studies with porcine eye, in vitro across corneal permeability studies.
- PAMPA assays.
- Dissolution kinetics assays.
- Physicochemical characterization of ophthalmic formulations – viscosity, mucoadhesivity, osmolarity and pH, chemical stability, zeta-potential analysis.
Why work with us
The core facility provides a comprehensive suite of advanced research services, from basic physicochemical characterisations to sophisticated in vitro and ex vivo efficacy and safety assessments of ophthalmic preparations/drugs, ensuring thorough evaluation and informed decision-making in the selection and advancement of promising candidates for preclinical and clinical development stages.
Our equipment
- μFLUX with Rainbow UV probes (Pion Inc.)
- Beckman Coulter Biomek FX Dual Arm System Robot
- Proprietary, in-house developed systems to investigate absorption
- Zeta potential analyzer
References
- https://doi.org/10.1002/chem.201704205
- http://dx.doi.org/10.1016/j.ejps.2016.10.034
- https://doi.org/10.3390/pharmaceutics15010278
- https://doi.org/10.1002/chem.201704205
- https://doi.org/10.1016/j.molliq.2022.120781