Head of Core Facility
György Tibor Balogh Prof. Dr.
István Mándity Dr.
Core Facility Address
Department of Pharmaceutical Chemistry
H-1092 Budapest,
Hőgyes Endre u. 7-9.
Contact E-mail
biomimox.medchem@semmelweis.hu
Staff
5
Quality Control
ISO9001
What we offer
- Biomimetic system for oxidative metabolite synthesis (flow chemistry, electrochemical oxidation, HTS in ambient mass spectrometry).
- Scanning electron microscopy and dynamic light scattering analysis.
Why work with us
Biomimetic oxidation of drugs catalyzed by metalloporphyrins using continuous flow chemistry is a powerful method for the effective synthesis of drug metabolites. Our core facility offers efficient synthesis of new API derivative and liver related phase I oxidation major metabolite characterization using immobilized catalysts or continuous-flow magnetic chip reactors.
Our equipment
- Immobilized porphyrin magnetic nanoparticle reactors
- HPLC-DAD-MS
- SEM/DLS
References
- https://doi.org/10.3390/mi10100668
- https://doi.org/10.1002/chem.201800892
- https://doi.org/10.1016/S0040-4020(99)00134-9