Head of Core Facility
István Mándity Dr.
György Tibor Balogh Prof. Dr..
Core Facility Address
Department of Organic Chemistry
H-1092 Budapest,
Hőgyes Endre u. 7-9.
Contact E-mail
peptide.medchem@semmelweis.hu
Staff
5
Quality Control
ISO9001
What we offer
- Peptide & Foldamer Design: Rational modeling for membrane activity, ion transport, and molecular recognition.
- Synthesis & Optimization: High-throughput solid-phase libraries (stapled, β-peptides, hybrids) with scalable, green options.
- Characterization: CD, NMR, HPLC-MS, and biophysical analysis of structure, stability, and binding.
- Structure–Function Platform: Sequence–activity exploration to fine-tune properties.
- Collaboration: R&D support for peptide-based tools, therapeutics, and materials.
Why work with us
Our platform combines deep expertise in peptide and foldamer science with advanced capabilities in design, synthesis, and characterization. We offer tailored solutions, rapid project execution, and a collaborative mindset to accelerate your innovation pipeline. Whether you’re targeting therapeutic leads, functional biomaterials, or novel molecular architectures, we provide precision, creativity, and reliability—backed by a strong track record of academic and industrial partnerships.
Our equipment
- Varian Mercury Plus 400 MHz NMR spectrometer
- Shimadzu LCMS-2020
- CEM MW reactor
- Continuous flow peptide synthesis reactor
- Schrödinger computational platform: Desmond, Jaguar, Maestro, Prime, PrimeX, PyMOL
- Gilson preparative HPLC purifcation system
References
- Our collaborating partners: Targetex, Pharmahungary
- doi.org/10.1038/s41467-024-47708-4
- doi.org/10.1111/bph.15509