{"id":956,"date":"2017-11-10T13:48:37","date_gmt":"2017-11-10T12:48:37","guid":{"rendered":"http:\/\/semmelweis.hu\/psychophysiology\/?p=956"},"modified":"2019-01-23T17:01:34","modified_gmt":"2019-01-23T16:01:34","slug":"eeg-transients-in-the-sigma-range-during-non-rem-sleep-predict-learning-in-dogs","status":"publish","type":"post","link":"https:\/\/semmelweis.hu\/psychophysiology\/2017\/11\/10\/eeg-transients-in-the-sigma-range-during-non-rem-sleep-predict-learning-in-dogs\/","title":{"rendered":"EEG Transients in the Sigma Range During non-REM Sleep Predict Learning in Dogs"},"content":{"rendered":"<p><i>Scientific Reports<\/i><b>\u00a07<\/b>, Article\u00a0number:\u00a012936 (2017)<\/p>\n<p><a href=\"http:\/\/dx.doi.org\/10.1038\/s41598-017-13278-3\" target=\"_blank\" rel=\"noopener\">Free full-text<\/a><\/p>\n<p>DOI:\u00a0 <a href=\"http:\/\/dx.doi.org\/10.1038\/s41598-017-13278-3\" target=\"_blank\" rel=\"noopener\">10.1038\/s41598-017-13278-3<\/a><\/p>\n<p>Ivaylo Borislavov Iotchev<sup>1<\/sup>, Anna Kis<sup>2<\/sup>, R\u00f3bert B\u00f3dizs<sup>3<\/sup>, Gilles van Luijtelaar<sup>4<\/sup> &amp; Enik\u0151 Kubinyi<sup>1<\/sup><\/p>\n<p><sup>1<\/sup>Department of Ethology, E\u00f6tv\u00f6s Lor\u00e1nd University, Budapest, Hungary<\/p>\n<p><sup>2<\/sup>Institute of Cognitive Neuroscience and Psychology, Hungarian Academy of Sciences, Budapest, Hungary<\/p>\n<p><sup>3<\/sup>Institute of Behavioural Sciences, Semmelweis University, Budapest, Hungary<\/p>\n<p><sup>4<\/sup>Donders Centre of Cognition, Radboud University, Nijmegen, The Netherlands<\/p>\n<p style=\"text-align: justify\">\u00a0<\/p>\n<p style=\"text-align: justify\"><strong>Abstract<\/strong><\/p>\n<p style=\"text-align: justify\">Sleep spindles are phasic bursts of thalamo-cortical activity, visible in the cortex as transient oscillations in the sigma range (usually defined in humans as 12\u201314 or 9\u201316\u2009Hz). They have been associated with sleep-dependent memory consolidation and sleep stability in humans and rodents. Occurrence, frequency, amplitude and duration of sleep spindles co-vary with age, sex and psychiatric conditions. Spindle analogue activity in dogs has been qualitatively described, but never quantified and related to function. In the present study we used an adjusted version of a detection method previously validated in children to test whether detections in the dogs show equivalent functional correlates as described in the human literature. We found that the density of EEG transients in the 9\u201316\u2009Hz range during non-REM sleep relates to memory and is characterized by sexual dimorphism similarly as in humans. The number of transients\/minute was larger in the learning condition and for female dogs, and correlated with the increase of performance during recall. It can be concluded that in dogs, automatic detections in the 9\u201316\u2009Hz range, in particular the slow variant (&lt;13\u2009Hz), are functional analogues of human spindles.<\/p>\n<p><strong>Keywords: <\/strong>consolidation, prognostic markers<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Scientific Reports\u00a07, Article\u00a0number:\u00a012936 (2017) <a href=\"http:\/\/dx.doi.org\/10.1038\/s41598-017-13278-3\" target=\"_blank\" rel=\"noopener\">Free full-text<\/a> DOI:\u00a0 <a href=\"http:\/\/dx.doi.org\/10.1038\/s41598-017-13278-3\" target=\"_blank\" rel=\"noopener\">10.1038\/s41598-017-13278-3<\/a> Ivaylo Borislavov Iotchev1, Anna Kis2, R\u00f3bert B\u00f3dizs3, Gilles van Luijtelaar4 &amp; Enik\u0151 Kubinyi1 1Department of Ethology, E\u00f6tv\u00f6s Lor\u00e1nd University, Budapest, Hungary 2Institute of Cognitive Neuroscience and Psychology, Hungarian Academy of Sciences, Budapest, Hungary 3Institute of Behavioural Sciences, Semmelweis University, Budapest, Hungary 4Donders Centre of Cognition, Radboud University, Nijmegen, The Netherlands &hellip;<\/p>\n","protected":false},"author":101277,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[6],"tags":[121,122],"class_list":["post-956","post","type-post","status-publish","format-standard","hentry","category-articles-in-professional-journals","tag-consolidation","tag-prognostic-markers"],"acf":[],"_links":{"self":[{"href":"https:\/\/semmelweis.hu\/psychophysiology\/wp-json\/wp\/v2\/posts\/956","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/semmelweis.hu\/psychophysiology\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/semmelweis.hu\/psychophysiology\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/semmelweis.hu\/psychophysiology\/wp-json\/wp\/v2\/users\/101277"}],"replies":[{"embeddable":true,"href":"https:\/\/semmelweis.hu\/psychophysiology\/wp-json\/wp\/v2\/comments?post=956"}],"version-history":[{"count":6,"href":"https:\/\/semmelweis.hu\/psychophysiology\/wp-json\/wp\/v2\/posts\/956\/revisions"}],"predecessor-version":[{"id":1388,"href":"https:\/\/semmelweis.hu\/psychophysiology\/wp-json\/wp\/v2\/posts\/956\/revisions\/1388"}],"wp:attachment":[{"href":"https:\/\/semmelweis.hu\/psychophysiology\/wp-json\/wp\/v2\/media?parent=956"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/semmelweis.hu\/psychophysiology\/wp-json\/wp\/v2\/categories?post=956"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/semmelweis.hu\/psychophysiology\/wp-json\/wp\/v2\/tags?post=956"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}