{"id":942,"date":"2017-11-10T14:05:58","date_gmt":"2017-11-10T13:05:58","guid":{"rendered":"http:\/\/semmelweis.hu\/psychophysiology\/?p=942"},"modified":"2019-01-23T16:57:36","modified_gmt":"2019-01-23T15:57:36","slug":"the-hemispheric-lateralization-of-sleep-spindles-in-humans","status":"publish","type":"post","link":"https:\/\/semmelweis.hu\/psychophysiology\/2017\/11\/10\/the-hemispheric-lateralization-of-sleep-spindles-in-humans\/","title":{"rendered":"The hemispheric lateralization of sleep spindles in humans"},"content":{"rendered":"

Sleep Spindles & Cortical Up States<\/em> 1:(1) pp.42-54 (2017)<\/p>\n

Free full-text<\/a><\/p>\n

DOI: 10.1556\/2053.01.2017.002<\/a><\/p>\n

R\u00f3bert B\u00f3dizs1,2,3*\u2020<\/sup>, Ferenc Gombos2\u2020<\/sup>, P\u00e9ter P. Ujma1,3<\/sup>, S\u00e1ra Szakad\u00e1t1<\/sup>, Piroska S\u00e1ndor1<\/sup>, P\u00e9ter Simor6,7<\/sup>, Adri\u00e1n P\u00f3t\u00e1ri6<\/sup>, Boris Nikolai Konrad4<\/sup>, Lisa Genzel8<\/sup>, Axel Steiger5<\/sup>, Martin Dresler4,5<\/sup> and Ilona Kov\u00e1cs2<\/sup><\/div>\n
\u00a0<\/div>\n
1<\/sup>Institute of Behavioural Sciences, Semmelweis University, Budapest, Hungary<\/div>\n
2<\/sup>Department of General Psychology, P\u00e1zm\u00e1ny P\u00e9ter Catholic University, Budapest, Hungary<\/div>\n
3<\/sup>National Institute of Clinical Neurosciences, Budapest, Hungary<\/div>\n
4<\/sup>Donders Institute for Brain, Cognition and Behaviour, Nijmegen, The Netherlands<\/div>\n
5<\/sup>Max Planck Institute of Psychiatry, Munich, Germany<\/div>\n
6<\/sup>Department of Cognitive Science, Budapest University of Technology and Economics, Budapest, Hungary<\/div>\n
7<\/sup>Ny\u00edr\u0151 Gyula Hospital, National Institute of Psychiatry and Addictions, Budapest, Hungary<\/div>\n
8<\/sup>Centre for Cognitive and Neural Systems, University of Edinburgh, Edinburgh, United Kingdom<\/div>\n

 <\/p>\n

Abstract<\/strong><\/p>\n

\n
\n

Females and males differ in several features of their spindle oscillations, as well as in the<\/span> hemispheric<\/span> lateralization<\/span> of their neurocognitive processes. In addition, the<\/span> hemispheric<\/span> lateralization<\/span> of cognitive functions was shown to vary in an age-dependent manner. In spite of the above knowledge, data on the<\/span> hemispheric<\/span> lateralization<\/span> of these oscillatory phenomena are scarce and no sex differences or age effects in the<\/span> hemispheric<\/span> lateralization<\/span> of sleep spindles were reported. Here, we aim to fill this gap by the description of the<\/span> hemispheric<\/span> lateralization<\/span> of sleep spindles in healthy human subjects. Data sets from three research groups were unified (N<\/i>\u2009=\u2009251, age range: 4\u221269 years, 122 females) in this retrospective multicenter study. The amplitude, density, and duration of slow (frontally dominant) and fast (centroparietally dominant) spindles were analyzed using the individual adjustment method. Hemispheric<\/span> lateralization<\/span> was quantified by the (L\u2009\u2212\u2009R)\/mean (L, R) index. Orbitofronto-temporo-occipital and parietal fast sleep spindle measures are left lateralized<\/span>, while prefrontal spindle amplitude is characterized by right hemispheric<\/span> dominance. Left lateralization<\/span> of fast spindle density and duration in the temporal and orbitofrontal regions, respectively, increases as a function of age in males, but not in females. In turn, females are characterized by higher left hemispheric<\/span> dominance in occipitally measured fast spindle durations as compared with males. Sleep spindles are asymmetrically distributed over the two hemispheres<\/span>. This phenomenon is sexually dimorphic and region-specific perhaps indexing sex differences in neurocognitive architectures.<\/p>\n<\/div>\n<\/div>\n

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Keywords:<\/b> sleep spindles; sigma activity; hemispheric lateralization; sexual dimorphism; gender differences; temporal lobe<\/div>\n<\/div>\n

 <\/p>\n","protected":false},"excerpt":{"rendered":"

Sleep Spindles & Cortical Up States 1:(1) pp.42-54 (2017) Free full-text<\/a> DOI: 10.1556\/2053.01.2017.002<\/a> R\u00f3bert B\u00f3dizs1,2,3*\u2020, Ferenc Gombos2\u2020, P\u00e9ter P. Ujma1,3, S\u00e1ra Szakad\u00e1t1, Piroska S\u00e1ndor1, P\u00e9ter Simor6,7, Adri\u00e1n P\u00f3t\u00e1ri6, Boris Nikolai Konrad4, Lisa Genzel8, Axel Steiger5, Martin Dresler4,5 and Ilona Kov\u00e1cs2 \u00a0 1Institute of Behavioural Sciences, Semmelweis University, Budapest, Hungary 2Department of General Psychology, P\u00e1zm\u00e1ny P\u00e9ter Catholic University, Budapest, …<\/p>\n","protected":false},"author":101277,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[6],"tags":[112,110,111,109,29,113],"class_list":["post-942","post","type-post","status-publish","format-standard","hentry","category-articles-in-professional-journals","tag-gender-differences","tag-hemispheric-lateralization","tag-sexual-dimorphism","tag-sigma-activity","tag-sleep-spindles","tag-temporal-lobe"],"acf":[],"_links":{"self":[{"href":"https:\/\/semmelweis.hu\/psychophysiology\/wp-json\/wp\/v2\/posts\/942","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/semmelweis.hu\/psychophysiology\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/semmelweis.hu\/psychophysiology\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/semmelweis.hu\/psychophysiology\/wp-json\/wp\/v2\/users\/101277"}],"replies":[{"embeddable":true,"href":"https:\/\/semmelweis.hu\/psychophysiology\/wp-json\/wp\/v2\/comments?post=942"}],"version-history":[{"count":7,"href":"https:\/\/semmelweis.hu\/psychophysiology\/wp-json\/wp\/v2\/posts\/942\/revisions"}],"predecessor-version":[{"id":1385,"href":"https:\/\/semmelweis.hu\/psychophysiology\/wp-json\/wp\/v2\/posts\/942\/revisions\/1385"}],"wp:attachment":[{"href":"https:\/\/semmelweis.hu\/psychophysiology\/wp-json\/wp\/v2\/media?parent=942"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/semmelweis.hu\/psychophysiology\/wp-json\/wp\/v2\/categories?post=942"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/semmelweis.hu\/psychophysiology\/wp-json\/wp\/v2\/tags?post=942"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}