{"id":1959,"date":"2022-11-14T15:13:01","date_gmt":"2022-11-14T14:13:01","guid":{"rendered":"https:\/\/semmelweis.hu\/psychophysiology\/?p=1959"},"modified":"2022-11-14T16:20:42","modified_gmt":"2022-11-14T15:20:42","slug":"role-of-anterior-thalamic-circuitry-during-sleep","status":"publish","type":"post","link":"https:\/\/semmelweis.hu\/psychophysiology\/2022\/11\/14\/role-of-anterior-thalamic-circuitry-during-sleep\/","title":{"rendered":"Role of anterior thalamic circuitry during sleep"},"content":{"rendered":"<p><strong>Role of anterior thalamic circuitry during sleep<\/strong><\/p>\n<p>Epilepsy Research, Volume 186, October 2022, 106999<\/p>\n<p>DOI: <a href=\"https:\/\/doi.org\/10.1016\/j.eplepsyres.2022.106999\" target=\"_blank\" rel=\"noopener\">10.1016\/j.eplepsyres.2022.106999<\/a><\/p>\n<p>Johanna Petra Szab\u00f3<sup>a,c<\/sup>, D\u00e1niel Fab\u00f3<sup>a<\/sup>, N\u00f3ra Pet\u0151<sup>a<\/sup>, Anna S\u00e1kovics<sup>a,c<\/sup>, R\u00f3bert B\u00f3dizs<sup>b<\/sup><\/p>\n<p><sup>a <\/sup>Dept of Neurology, National Institute of Mental Health, Neurology and Neurosurgery, 1145 Budapest, Hungary<\/p>\n<p><sup>b <\/sup>Institute of Behavioral Sciences, Semmelweis University, 1089 Budapest, Hungary<\/p>\n<p><sup>c <\/sup>J\u00e1nos Szent\u00e1gothai Doctoral School of Neurosciences, 1085 Budapest, Hungary<\/p>\n<p><strong>Abstract<\/strong><\/p>\n<p>Increased attention has been paid to the structure and function of anterior nucleus of the thalamus (ANT), since deep brain stimulation (DBS) treatment for epilepsy launched a decade ago. The efficacy of the treatment on seizure count varies patient from patient and we have limited information on the predictors of better outcomes.<\/p>\n<p>While the thalamus is considered the key brain region responsible for maintaining sleep, ANT was traditionally not involved in this function. Recent experimental and human data point to a possible role of ANT in sleep processes, although the underlying mechanisms are still ambiguous. Beside evaluating the current knowledge on sleep disturbances experienced during ANT-DBS treatment, the search for valid biomarkers primarily resides on a better understanding of sleep circuits implicating ANT and its subnuclei. Hypothetically better selectivity within the target may increase seizure outcomes and reduce psychiatric and cognitive side effects.<\/p>\n<p>Hence, the main scope of this review is to summarize the evidence on the activity measured in the ANT during non-REM and REM sleep. Furthermore, we aim to find shared properties of sleep processes and ANT-related functions examined more thoroughly during wakefulness, such as selective attention and memory.<\/p>\n<p><strong>Keywords:<\/strong> anterior nucleus of the thalamus; DBS; epilepsy; sleep<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Role of anterior thalamic circuitry during sleep Epilepsy Research, Volume 186, October 2022, 106999 DOI: <a href=\"https:\/\/doi.org\/10.1016\/j.eplepsyres.2022.106999\" target=\"_blank\" rel=\"noopener\">10.1016\/j.eplepsyres.2022.106999<\/a> Johanna Petra Szab\u00f3a,c, D\u00e1niel Fab\u00f3a, N\u00f3ra Pet\u0151a, Anna S\u00e1kovicsa,c, R\u00f3bert B\u00f3dizsb a Dept of Neurology, National Institute of Mental Health, Neurology and Neurosurgery, 1145 Budapest, Hungary b Institute of Behavioral Sciences, Semmelweis University, 1089 Budapest, Hungary c J\u00e1nos Szent\u00e1gothai Doctoral &hellip;<\/p>\n","protected":false},"author":101277,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[6,141],"tags":[],"class_list":["post-1959","post","type-post","status-publish","format-standard","hentry","category-articles-in-professional-journals","category-most-recent-articles"],"acf":[],"_links":{"self":[{"href":"https:\/\/semmelweis.hu\/psychophysiology\/wp-json\/wp\/v2\/posts\/1959","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/semmelweis.hu\/psychophysiology\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/semmelweis.hu\/psychophysiology\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/semmelweis.hu\/psychophysiology\/wp-json\/wp\/v2\/users\/101277"}],"replies":[{"embeddable":true,"href":"https:\/\/semmelweis.hu\/psychophysiology\/wp-json\/wp\/v2\/comments?post=1959"}],"version-history":[{"count":2,"href":"https:\/\/semmelweis.hu\/psychophysiology\/wp-json\/wp\/v2\/posts\/1959\/revisions"}],"predecessor-version":[{"id":1977,"href":"https:\/\/semmelweis.hu\/psychophysiology\/wp-json\/wp\/v2\/posts\/1959\/revisions\/1977"}],"wp:attachment":[{"href":"https:\/\/semmelweis.hu\/psychophysiology\/wp-json\/wp\/v2\/media?parent=1959"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/semmelweis.hu\/psychophysiology\/wp-json\/wp\/v2\/categories?post=1959"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/semmelweis.hu\/psychophysiology\/wp-json\/wp\/v2\/tags?post=1959"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}