{"id":1897,"date":"2021-11-12T17:07:44","date_gmt":"2021-11-12T16:07:44","guid":{"rendered":"https:\/\/semmelweis.hu\/psychophysiology\/?p=1897"},"modified":"2021-11-12T17:07:44","modified_gmt":"2021-11-12T16:07:44","slug":"bodizs-horvath-szalardy-ujma-et-al-sleep-spindle-frequency-overnight-dynamics-afternoon-nap-effects-and-possible-circadian-modulation","status":"publish","type":"post","link":"https:\/\/semmelweis.hu\/psychophysiology\/2021\/11\/12\/bodizs-horvath-szalardy-ujma-et-al-sleep-spindle-frequency-overnight-dynamics-afternoon-nap-effects-and-possible-circadian-modulation\/","title":{"rendered":"B\u00f3dizs-Horv\u00e1th-Szal\u00e1rdy-Ujma-et-al: Sleep-spindle frequency: Overnight dynamics, afternoon nap effects, and possible circadian modulation"},"content":{"rendered":"<p>Journal of Sleep Research 2021; e13514. pp.1-13 (2021)<br \/>\nDOI: https:\/\/doi.org\/10.1111\/jsr.13514; <a href=\"https:\/\/doi.org\/10.1111\/jsr.13514\" target=\"_blank\" rel=\"noopener noreferrer\">Free full-text<\/a><br \/>\nB\u00f3dizs R<sup>1,2<\/sup>, Horv\u00e1th CG<sup>1<\/sup>, Szal\u00e1rdy O<sup>1,3<\/sup>, Ujma PP<sup>1,2<\/sup>, Simor PP<sup>1,4,5<\/sup>, Gombos F<sup>6,7<\/sup>, Kov\u00e1cs I<sup>6<\/sup>, Genzel L<sup>8<\/sup>, Dresler M<sup>8<\/sup><\/p>\n<p><sup>1<\/sup>Institute of Behavioural Sciences, Semmelweis University, Budapest, Hungary<br \/>\n<sup>2<\/sup>National Institute of Clinical Neurosciences, Budapest, Hungary<br \/>\n<sup>3<\/sup>Institute of Cognitive Neuroscience and Psychology, Research Centre for Natural Sciences, Budapest, Hungary<br \/>\n<sup>4<\/sup>Institute of Psychology, ELTE E\u00f6tv\u00f6s Lor\u00e1nd University, Budapest, Hungary<br \/>\n<sup>5<\/sup><span class=\"accordion-tabbed__tab-mobile  accordion__closed\">UR2NF, Neuropsychology and Functional Neuroimaging Research Unit at CRCN \u2013 Center for Research in Cognition and Neurosciences and UNI \u2013 ULB Neurosciences Institute, Universit\u00e9 Libre de Bruxelles (ULB), Brussels, Belgium<br \/>\n<\/span><sup>6<\/sup>Department of General Psychology, P\u00e1zm\u00e1ny P\u00e9ter Catholic University, Budapest, Hungary<br \/>\n<sup>7<\/sup>MTA-PPKE Adolescent Development Research Group, Budapest, Hungary<br \/>\n<sup>8<\/sup><span class=\"accordion-tabbed__tab-mobile  accordion__closed\">Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, Nijmegen, The Netherlands<\/span><\/p>\n<p><strong>Summary<\/strong><\/p>\n<p>Homeostatic and circadian processes play a pivotal role in determining sleep structure, timing, and quality. In sharp contrast with the wide accessibility of the electroencephalogram (EEG) index of sleep homeostasis, an electrophysiological measure of the circadian modulation of sleep is still unavailable. Evidence suggests that sleep-spindle frequencies decelerate during biological night. In order to test the feasibility of measuring this marker in common polysomnographic protocols, the Budapest-Munich database of sleep records (<em>N<\/em>\u00a0=\u00a0251\u00a0healthy subjects, 122 females, age range: 4\u201369\u00a0years), as well as an afternoon nap sleep record database (<em>N<\/em>\u00a0=\u00a0112\u00a0healthy subjects, 30 females, age range: 18\u201330\u00a0years) were analysed by the individual adjustment method of sleep-spindle analysis. Slow and fast sleep-spindle frequencies were characterised by U-shaped overnight dynamics, with highest values in the first and the fourth-to-fifth sleep cycle and the lowest values in the middle of the sleeping period (cycles two to three). Age-related attenuation of sleep-spindle deceleration was evident. Estimated phases of the nadirs in sleep-spindle frequencies were advanced in children as compared to other age groups. Additionally, nap sleep spindles were faster than night sleep spindles (0.57 and 0.39\u00a0Hz difference for slow and fast types, respectively). The fine frequency resolution analysis of sleep spindles is a feasible method of measuring the assumed circadian modulation of sleep. Moreover, age-related attenuation of circadian sleep modulation might be measurable by assessing the overnight dynamics in sleep-spindle frequency. Phase of the minimal sleep-spindle frequency is a putative biomarker of chronotype.<\/p>\n<p>&nbsp;<\/p>\n<div class=\"abstract-group\">\n<section id=\"section-1-en\" class=\"article-section article-section__abstract\" lang=\"en\" data-lang=\"en\">\n<div class=\"article-section__content en main\">\n<p>&nbsp;<\/p>\n<\/div>\n<\/section>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>Journal of Sleep Research 2021; e13514. pp.1-13 (2021) DOI: https:\/\/doi.org\/10.1111\/jsr.13514; <a href=\"https:\/\/doi.org\/10.1111\/jsr.13514\" target=\"_blank\" rel=\"noopener noreferrer\">Free full-text<\/a> B\u00f3dizs R1,2, Horv\u00e1th CG1, Szal\u00e1rdy O1,3, Ujma PP1,2, Simor PP1,4,5, Gombos F6,7, Kov\u00e1cs I6, Genzel L8, Dresler M8 1Institute of Behavioural Sciences, Semmelweis University, Budapest, Hungary 2National Institute of Clinical Neurosciences, Budapest, Hungary 3Institute of Cognitive Neuroscience and Psychology, Research Centre for Natural Sciences, Budapest, &hellip;<\/p>\n","protected":false},"author":101277,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[6,141],"tags":[],"class_list":["post-1897","post","type-post","status-publish","format-standard","hentry","category-articles-in-professional-journals","category-most-recent-articles"],"acf":[],"_links":{"self":[{"href":"https:\/\/semmelweis.hu\/psychophysiology\/wp-json\/wp\/v2\/posts\/1897","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/semmelweis.hu\/psychophysiology\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/semmelweis.hu\/psychophysiology\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/semmelweis.hu\/psychophysiology\/wp-json\/wp\/v2\/users\/101277"}],"replies":[{"embeddable":true,"href":"https:\/\/semmelweis.hu\/psychophysiology\/wp-json\/wp\/v2\/comments?post=1897"}],"version-history":[{"count":1,"href":"https:\/\/semmelweis.hu\/psychophysiology\/wp-json\/wp\/v2\/posts\/1897\/revisions"}],"predecessor-version":[{"id":1899,"href":"https:\/\/semmelweis.hu\/psychophysiology\/wp-json\/wp\/v2\/posts\/1897\/revisions\/1899"}],"wp:attachment":[{"href":"https:\/\/semmelweis.hu\/psychophysiology\/wp-json\/wp\/v2\/media?parent=1897"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/semmelweis.hu\/psychophysiology\/wp-json\/wp\/v2\/categories?post=1897"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/semmelweis.hu\/psychophysiology\/wp-json\/wp\/v2\/tags?post=1897"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}