{"id":9043,"date":"2012-11-29T04:00:43","date_gmt":"2012-11-29T03:00:43","guid":{"rendered":"http:\/\/semmelweis.hu\/phd\/2012\/11\/29\/allashirdetes-3-2\/"},"modified":"2012-11-29T04:00:43","modified_gmt":"2012-11-29T03:00:43","slug":"allashirdetes-3-2","status":"publish","type":"post","link":"https:\/\/semmelweis.hu\/phd\/2012\/11\/29\/allashirdetes-3-2\/","title":{"rendered":"Orvosbiol\u00f3giai kutat\u00f3i \u00e1ll\u00e1s"},"content":{"rendered":"

Tudom\u00e1nyos kutat\u00f3i \u00e1ll\u00e1shirdet\u00e9s <\/strong>
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A Semmelweis Egyetem, \u00c1OK, K\u00f3r\u00e9lettani Int\u00e9zete, Nephrologiai Kutat\u00f3 \u00e9s K\u00e9pz\u0151 K\u00f6zpontja<\/p>\n

ORVOS \/ BIOL\u00d3GUS munkat\u00e1rsat keres <\/strong>
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orvosbiol\u00f3giai kutat\u00f3i \u00e1ll\u00e1s bet\u00f6lt\u00e9s\u00e9re.
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Kutat\u00e1si ter\u00fclet:<\/strong>
Vesefibr\u00f3zis molekul\u00e1ris pathomechianizmus\u00e1nak in vivo \u00e9s in vitro vizsg\u00e1lata diabetesben, illetve TGF-\u00df induk\u00e1lt fibr\u00f3zis modellekben.
\u00a0
Kutat\u00e1si t\u00e9m\u00e1k:<\/strong>
–\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 A podocit\u00e1k \u00e9s mesangi\u00e1lis sejtek diabeteses k\u00e1rosod\u00e1s\u00e1nak molekul\u00e1ris mechanizmusai
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–\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 A TGF-beta induk\u00e1lt myocardi\u00e1lis- \u00e9s vesefibr\u00f3zis progresszi\u00f3j\u00e1nak molekul\u00e1ris mechanizmusainak felt\u00e1r\u00e1sa
(A kutat\u00e1si t\u00e9m\u00e1k egyben meghirdetett PhD t\u00e9m\u00e1k is.)
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T\u00e9mavezet\u0151:<\/strong> Dr. K\u00f6k\u00e9ny G\u00e1bor PhD
\u00a0<\/strong>
Feladatok:<\/strong>
–\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 diabeteses \u00e1llatmodellek (eg\u00e9r, ill. patk\u00e1ny) alkalmaz\u00e1sa, fibr\u00f3zis indukci\u00f3ja
–\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 TGF-\u00df transzgenikus egerekben a transzg\u00e9n hat\u00e1s\u00e1nak vizsg\u00e1lata elt\u00e9r\u0151 genetikai h\u00e1tt\u00e9ren
–\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 podocita, mesangi\u00e1lis \u00e9s tubulus sejtteny\u00e9szetben hiperglik\u00e9mia, TGF-\u00df \u00e9s AngII \u00a0kiv\u00e1ltotta k\u00fcl\u00f6nb\u00f6z\u0151 jel\u00e1tviteli utak vizsg\u00e1lata, azok serkent\u00e9se ill. g\u00e1tl\u00e1sa
–\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 genotipiz\u00e1l\u00e1s, sz\u00f6vet- ill. sejtmint\u00e1k molekul\u00e1ris anal\u00edzise (feh\u00e9rje- ill. g\u00e9nexpresszi\u00f3 vizsg\u00e1lata)
–\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 m\u00e9r\u00e9si adatok feldolgoz\u00e1sa
–\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 TDK hallgat\u00f3k munk\u00e1j\u00e1nak fel\u00fcgyelete
\u00a0
Alkalmazott m\u00f3dszerek:<\/strong>
\u00c1llatok kezel\u00e9se, \u00e1llati sz\u00f6vetek perf\u00fazi\u00f3ja, sejtteny\u00e9szt\u00e9s, immunhiszok\u00e9mia \u00e9s immuncitok\u00e9mia, qualitat\u00edv PCR, mRNS \u00e9s miRNS expresszi\u00f3 m\u00e9r\u00e9s quantitat\u00edv PCR-el, ChIP-PCR, immunoblot technik\u00e1k, analitikai m\u00f3dszerek, ELISA.
\u00a0
Jelentkez\u00e9si felt\u00e9telek:<\/strong>
–\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Orvosi vagy biol\u00f3gusi v\u00e9gzetts\u00e9g,
–\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Angol nyelvtud\u00e1s (C t\u00edpus\u00fa nyelvvizsga)
\u00a0<\/strong>
P\u00e1ly\u00e1z\u00e1sn\u00e1l el\u0151ny: <\/strong>
–\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Laborat\u00f3riumi tapasztalat, ill. j\u00e1rtass\u00e1g sz\u00f6vettani \u00e9s\/vagy molekul\u00e1ris biol\u00f3giai, sejtteny\u00e9szt\u00e9si m\u00f3dszerekben
–\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 N\u00e9met nyelvtud\u00e1s
\u00a0<\/strong>
Az \u00e1ll\u00e1s bet\u00f6lthet\u0151: <\/strong>2013. janu\u00e1r 1-t\u0151l
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A t\u00e9m\u00e1kkal kapcsolatos tov\u00e1bbi inform\u00e1ci\u00f3k az al\u00e1bbi helyeken tal\u00e1lhat\u00f3k: <\/strong>
http:\/\/www.doktori.hu\/index.php?menuid=195&tk_ID=55834<\/a><\/strong>
http:\/\/www.doktori.hu\/index.php?menuid=195&tk_ID=53743<\/a>
\u00a0<\/strong>
A t\u00e9mavezet\u0151 k\u00f6zlem\u00e9nyjegyz\u00e9ke: <\/strong>
https:\/\/vm.mtmt.hu\/\/search\/slist.php?lang=0&AuthorID=10014641<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

Tudom\u00e1nyos kutat\u00f3i \u00e1ll\u00e1shirdet\u00e9s <\/p>\n","protected":false},"author":158,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[2],"tags":[],"class_list":["post-9043","post","type-post","status-publish","format-standard","hentry","category-allasajanlatok"],"acf":[],"_links":{"self":[{"href":"https:\/\/semmelweis.hu\/phd\/wp-json\/wp\/v2\/posts\/9043","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/semmelweis.hu\/phd\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/semmelweis.hu\/phd\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/semmelweis.hu\/phd\/wp-json\/wp\/v2\/users\/158"}],"replies":[{"embeddable":true,"href":"https:\/\/semmelweis.hu\/phd\/wp-json\/wp\/v2\/comments?post=9043"}],"version-history":[{"count":0,"href":"https:\/\/semmelweis.hu\/phd\/wp-json\/wp\/v2\/posts\/9043\/revisions"}],"wp:attachment":[{"href":"https:\/\/semmelweis.hu\/phd\/wp-json\/wp\/v2\/media?parent=9043"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/semmelweis.hu\/phd\/wp-json\/wp\/v2\/categories?post=9043"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/semmelweis.hu\/phd\/wp-json\/wp\/v2\/tags?post=9043"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}