{"id":12059,"date":"2020-09-02T12:44:57","date_gmt":"2020-09-02T10:44:57","guid":{"rendered":"https:\/\/semmelweis.hu\/phd\/?p=12059"},"modified":"2020-12-03T09:30:45","modified_gmt":"2020-12-03T08:30:45","slug":"postdoctoral-fellow-physiology","status":"publish","type":"post","link":"https:\/\/semmelweis.hu\/phd\/2020\/09\/02\/postdoctoral-fellow-physiology\/","title":{"rendered":"Postdoctoral Fellow\/Physiology"},"content":{"rendered":"<p><strong>Postdoctoral Fellow\/Physiology<\/strong><\/p>\n<p>The University of Tennessee Health Science Center (UTHSC)<\/p>\n<p>See <a href=\"https:\/\/www.nature.com\/naturecareers\/job\/732626\">https:\/\/www.nature.com\/naturecareers\/job\/732626 <\/a>\u00a0or <a href=\"https:\/\/www.higheredjobs.com\/details.cfm?JobCode=177363255\">https:\/\/www.higheredjobs.com\/details.cfm?JobCode=177363255<\/a>\u00a0<\/p>\n<p>Memphis, TN, United States<\/p>\n<p>A Postdoctoral Fellow position is available in the research team of Professor Gabor Tigyi laboratory, Department of Physiology, University of Tennessee Health Science Center. The postdoctoral fellow and research team will investigate the radiation protective mechanism of action of lysophosphatidic acid analogs.\u00a0 Specifically, we are interested in determining the regulation of signalosomes that are responsible for the augmentation of\u00a0DNA\u00a0repair and reduction of apoptosis elicited by the long-duration activation of the lysophosphatidic acid receptor 2.\u00a0 A particular focus of these studies is on the adapter protein encoded by the immediate-early gene product\u00a0IEX-1.\u00a0IEX-1 has the ability to form supramolecular complexes with the\u00a0AKT\u00a0and ERK1\/2 kinases, inhibits the PP2A phosphatase and leads to activation of\u00a0DNA-dependent Protein Kinase, which in turn promotes high-fidelity double-strand\u00a0DNA\u00a0repair in cells exposed to genotoxic stress. (<strong>Please read background references: Patil et al.,\u00a0PMID:25619933; Balogh et al.\u00a0PMID\u00a026027517, Kuo et al.\u00a0PMID:30063964, Tigyi et al\u00a0PMID:3069214<\/strong><\/p>\n<p>The postdoctoral fellow should have strong background and experience in biochemical techniques in molecular signaling and\u00a0DNA\u00a0repair. Experience using co-immunoprecipitation, Western blotting, immunohistochemistry, cell culture, transduction\/transfection methods is required.\u00a0<\/p>\n<p>Qualifications:<\/p>\n<p>PhD, strong background in signal transduction research and radiation biology<\/p>\n<p>Interested individuals should send CV to Professor Gabor Tigyi via email (<a href=\"mailto:gtigyi@uthsc.edu\">gtigyi@uthsc.edu<\/a>).<\/p>\n<p>Salary will be commensurate with relevant experience and is competitive for postdoctoral fellows. The position includes an excellent benefits package (<a href=\"http:\/\/www.uthsc.edu\/postdoc\/benefits.php\">http:\/\/www.uthsc.edu\/postdoc\/benefits.php<\/a>). Located in Memphis, a dynamic Mid-South city rich in culture, history, diversity, music and cuisine, the\u00a0<a href=\"http:\/\/www.uthsc.edu\/\">University of Tennessee Health Science Center<\/a>\u00a0is one of the largest, most comprehensive academic health centers in the United States with a solid commitment to postdoctoral training.\u00a0UTHSC\u00a0is an<em>\u00a0EEO\/AA\/Title VI\/Title IX\/Section 504\/ADA\/ADEA\/V institution in the provision of its education and employment programs and services.<\/em><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Postdoctoral Fellow\/Physiology The University of Tennessee Health Science Center (UTHSC) See <a href=\"https:\/\/www.nature.com\/naturecareers\/job\/732626\">https:\/\/www.nature.com\/naturecareers\/job\/732626 <\/a> \u00a0or <a href=\"https:\/\/www.higheredjobs.com\/details.cfm?JobCode=177363255\">https:\/\/www.higheredjobs.com\/details.cfm?JobCode=177363255<\/a> \u00a0 Memphis, TN, United States A Postdoctoral Fellow position is available in the research team of Professor Gabor Tigyi laboratory, Department of Physiology, University of Tennessee Health Science Center. The postdoctoral fellow and research team will investigate the radiation protective mechanism of action &hellip;<\/p>\n","protected":false},"author":101719,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[2],"tags":[],"class_list":["post-12059","post","type-post","status-publish","format-standard","hentry","category-allasajanlatok"],"acf":[],"_links":{"self":[{"href":"https:\/\/semmelweis.hu\/phd\/wp-json\/wp\/v2\/posts\/12059","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/semmelweis.hu\/phd\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/semmelweis.hu\/phd\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/semmelweis.hu\/phd\/wp-json\/wp\/v2\/users\/101719"}],"replies":[{"embeddable":true,"href":"https:\/\/semmelweis.hu\/phd\/wp-json\/wp\/v2\/comments?post=12059"}],"version-history":[{"count":3,"href":"https:\/\/semmelweis.hu\/phd\/wp-json\/wp\/v2\/posts\/12059\/revisions"}],"predecessor-version":[{"id":12493,"href":"https:\/\/semmelweis.hu\/phd\/wp-json\/wp\/v2\/posts\/12059\/revisions\/12493"}],"wp:attachment":[{"href":"https:\/\/semmelweis.hu\/phd\/wp-json\/wp\/v2\/media?parent=12059"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/semmelweis.hu\/phd\/wp-json\/wp\/v2\/categories?post=12059"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/semmelweis.hu\/phd\/wp-json\/wp\/v2\/tags?post=12059"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}