{"id":311,"date":"2025-07-03T14:58:02","date_gmt":"2025-07-03T12:58:02","guid":{"rendered":"https:\/\/semmelweis.hu\/kfipalyazat\/?page_id=311"},"modified":"2026-04-09T13:51:14","modified_gmt":"2026-04-09T11:51:14","slug":"2020-2-1-1-ed-2022-00198","status":"publish","type":"page","link":"https:\/\/semmelweis.hu\/kfipalyazat\/palyazatok\/hazai-palyazatok\/nkfih\/kormanyzati-onero-alap\/2020-2-1-1-ed-2022-00198\/","title":{"rendered":"2020-2.1.1-ED-2022-00198"},"content":{"rendered":"

Projekt azonos\u00edt\u00f3 sz\u00e1ma: <\/strong>2020-2.1.1-ED-2022-00198<\/p>\n

A projekt c\u00edme:<\/strong> Cellul\u00e1ris \u00e9s humor\u00e1lis immunv\u00e1lasz vizsg\u00e1lata SARS-CoV-2 fert\u0151z\u00e9sen \u00e1tesett, illetve v\u00e9d\u0151olt\u00e1sban r\u00e9szes\u00fclt rheumatoid arthritises betegek k\u00f6r\u00e9ben<\/p>\n

 <\/p>\n

Projekt megval\u00f3s\u00edt\u00e1s\u00e1nak kezdete: <\/strong>2022.04.01.<\/p>\n

Projekt fizikai befejez\u00e9s\u00e9nek hat\u00e1rideje: <\/strong>2024.07.31.<\/p>\n

 <\/p>\n

T\u00e1mogat\u00e1s \u00f6sszege:<\/strong> 28.320.000 Ft<\/p>\n

T\u00e1mogat\u00e1s intenzit\u00e1sa:<\/strong>\u00a0100%<\/p>\n

\u00a0<\/p>\n

Projektr\u0151l:\u00a0<\/strong>
\nA rheumatoid arthritis (RA) kr\u00f3nikus, sziszt\u00e9m\u00e1s, ismeretlen eredet\u0171, autoimmun megbeteged\u00e9s, ami els\u0151dlegesen a k\u00e9z-, \u00e9s a l\u00e1b\u00edz\u00fcleteket \u00e9rinti. Ezen elv\u00e1ltoz\u00e1sok eredm\u00e9nyek\u00e9ppen \u00edz\u00fcleti f\u00e1jdalom, mozg\u00e1skorl\u00e1tozotts\u00e1g alakulhat ki, klasszikusan szimmetrikus gyullad\u00e1sos polyarthritis k\u00e9p\u00e9ben. Ismert, hogy az autoimmun betegs\u00e9gekben az eg\u00e9sz\u00e9ges popul\u00e1ci\u00f3hoz k\u00e9pest nagyobb a SARS-CoV-2 infekci\u00f3 vesz\u00e9lye.
\nSz\u00e1mos klinikai vizsg\u00e1lat igazolta a k\u00fcl\u00f6nb\u00f6z\u0151 SARS-CoV-2 elleni v\u00e9d\u0151olt\u00e1sok hat\u00e9konys\u00e1g\u00e1t. Nagysz\u00e1m\u00fa kutat\u00e1s bizony\u00edtotta, hogy a fert\u0151z\u00f6tt betegek szervezet\u00e9ben kialakul\u00f3 humor\u00e1lis immunv\u00e1lasz mellett a specifikus T-sejtes immunv\u00e1lasz k\u00e9pes kontroll\u00e1lni a v\u00edrusreplik\u00e1ci\u00f3t \u00e9s ez\u00e1ltal cs\u00f6kkenteni a betegs\u00e9g s\u00falyoss\u00e1g\u00e1t. A keletkez\u0151 anti-spike (S) \u00e9s anti-nukleocapsid (N) IgG antitestek v\u00e9delmet biztos\u00edtanak a fert\u0151z\u00e9s ellen a fert\u0151z\u00e9st k\u00f6vet\u0151 legal\u00e1bb 6 h\u00f3napban. Mind a lezajlott fert\u0151z\u00e9st, mind a v\u00e9d\u0151olt\u00e1st k\u00f6vet\u0151en a humor\u00e1lis \u00e9s a sejtes immunv\u00e1lasz egy\u00fcttes \u00e9rt\u00e9kel\u00e9se j\u00f3 k\u00e9pet adhat arr\u00f3l, hogy milyen m\u00e9rt\u00e9k\u0171 a v\u00e9delem.<\/p>\n

A kutat\u00e1s sor\u00e1n a cellul\u00e1ris \u00e9s humor\u00e1lis immunv\u00e1laszt vizsg\u00e1lj\u00e1k a SARS-CoV-2 fert\u0151z\u00e9sen \u00e1tesett, illetve v\u00e9d\u0151olt\u00e1sban r\u00e9szes\u00fclt RA-s betegek k\u00f6r\u00e9ben.<\/p>\n

A kutat\u00e1si program eredm\u00e9nyei felhaszn\u00e1lhat\u00f3k a rheumatoid arthritis \u00e9s a fert\u0151z\u00e9s \u00f6sszef\u00fcgg\u00e9seinek felismer\u00e9s\u00e9re, a betegs\u00e9g egy\u00fcttes komplik\u00e1ci\u00f3inak megel\u0151z\u00e9s\u00e9re, a betegek egyens\u00falyi \u00e1llapot\u00e1nak fenntart\u00e1s\u00e1ra.<\/p>\n

<\/p>\n","protected":false},"excerpt":{"rendered":"

Projekt azonos\u00edt\u00f3 sz\u00e1ma: 2020-2.1.1-ED-2022-00198 A projekt c\u00edme: Cellul\u00e1ris \u00e9s humor\u00e1lis immunv\u00e1lasz vizsg\u00e1lata SARS-CoV-2 fert\u0151z\u00e9sen \u00e1tesett, illetve v\u00e9d\u0151olt\u00e1sban r\u00e9szes\u00fclt rheumatoid arthritises betegek k\u00f6r\u00e9ben   Projekt megval\u00f3s\u00edt\u00e1s\u00e1nak kezdete: 2022.04.01. Projekt fizikai befejez\u00e9s\u00e9nek hat\u00e1rideje: 2024.07.31.   T\u00e1mogat\u00e1s \u00f6sszege: 28.320.000 Ft T\u00e1mogat\u00e1s intenzit\u00e1sa:\u00a0100% \u00a0 Projektr\u0151l:\u00a0 A rheumatoid arthritis (RA) kr\u00f3nikus, sziszt\u00e9m\u00e1s, ismeretlen eredet\u0171, autoimmun megbeteged\u00e9s, ami els\u0151dlegesen a k\u00e9z-, …<\/p>\n","protected":false},"author":102410,"featured_media":0,"parent":229,"menu_order":3,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"footnotes":""},"categories":[],"tags":[],"class_list":["post-311","page","type-page","status-publish","hentry"],"acf":[],"_links":{"self":[{"href":"https:\/\/semmelweis.hu\/kfipalyazat\/wp-json\/wp\/v2\/pages\/311","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/semmelweis.hu\/kfipalyazat\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/semmelweis.hu\/kfipalyazat\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/semmelweis.hu\/kfipalyazat\/wp-json\/wp\/v2\/users\/102410"}],"replies":[{"embeddable":true,"href":"https:\/\/semmelweis.hu\/kfipalyazat\/wp-json\/wp\/v2\/comments?post=311"}],"version-history":[{"count":5,"href":"https:\/\/semmelweis.hu\/kfipalyazat\/wp-json\/wp\/v2\/pages\/311\/revisions"}],"predecessor-version":[{"id":1044,"href":"https:\/\/semmelweis.hu\/kfipalyazat\/wp-json\/wp\/v2\/pages\/311\/revisions\/1044"}],"up":[{"embeddable":true,"href":"https:\/\/semmelweis.hu\/kfipalyazat\/wp-json\/wp\/v2\/pages\/229"}],"wp:attachment":[{"href":"https:\/\/semmelweis.hu\/kfipalyazat\/wp-json\/wp\/v2\/media?parent=311"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/semmelweis.hu\/kfipalyazat\/wp-json\/wp\/v2\/categories?post=311"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/semmelweis.hu\/kfipalyazat\/wp-json\/wp\/v2\/tags?post=311"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}