{"id":369,"date":"2013-05-16T19:06:40","date_gmt":"2012-09-11T13:40:47","guid":{"rendered":"http:\/\/semmelweis-egyetem.hu\/immun-patofiziologia\/?page_id=369"},"modified":"2026-03-11T15:38:37","modified_gmt":"2026-03-11T14:38:37","slug":"general-information","status":"publish","type":"page","link":"https:\/\/semmelweis.hu\/immun-patofiziologia\/en\/general-information\/","title":{"rendered":"General information"},"content":{"rendered":"<div class=\"keretes w-100\">\n<h2>Current field of research:<\/h2>\n<p><span data-olk-copy-source=\"MessageBody\">The role of acute phase proteins focusing on fibrinogen in the pathomechanism and the treatment of breast cancer with modulated electro-hypertemia and of renal fibrosis induced by acute ischemic kidney damage.<\/span><\/p>\n<\/div>\n<p style=\"text-align: center\"><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-2399 aligncenter\" src=\"https:\/\/semmelweis.hu\/immun-patofiziologia\/files\/2026\/01\/csoportkep-1.png\" alt=\"\" width=\"879\" height=\"342\" srcset=\"https:\/\/semmelweis.hu\/immun-patofiziologia\/files\/2026\/01\/csoportkep-1.png 2046w, https:\/\/semmelweis.hu\/immun-patofiziologia\/files\/2026\/01\/csoportkep-1-300x117.png 300w, https:\/\/semmelweis.hu\/immun-patofiziologia\/files\/2026\/01\/csoportkep-1-1024x398.png 1024w, https:\/\/semmelweis.hu\/immun-patofiziologia\/files\/2026\/01\/csoportkep-1-768x299.png 768w, https:\/\/semmelweis.hu\/immun-patofiziologia\/files\/2026\/01\/csoportkep-1-1536x598.png 1536w, https:\/\/semmelweis.hu\/immun-patofiziologia\/files\/2026\/01\/csoportkep-1-753x293.png 753w\" sizes=\"auto, (max-width: 879px) 100vw, 879px\" \/><\/p>\n<p style=\"text-align: center\"><span style=\"font-size: 14px\">Sz\u00e9n\u00e1si G\u00e1bor, Yibo Gu, B\u00f3csi D\u00e1niel, Qusay Abdalla, Eslam Abdalalem, Mohamed Elsalahaty, Hakim Al-murshidy, Hamar P\u00e9ter, Evan Santo, Ebsa Ahmed, Mingming He, Ko\u00f3s Zolt\u00e1n<\/span><\/p>\n<h2><a href=\"https:\/\/semmelweis.hu\/immun-patofiziologia\/files\/2026\/03\/csoportkep-2.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-2415 aligncenter\" src=\"https:\/\/semmelweis.hu\/immun-patofiziologia\/files\/2026\/03\/csoportkep-2.jpg\" alt=\"\" width=\"630\" height=\"441\" srcset=\"https:\/\/semmelweis.hu\/immun-patofiziologia\/files\/2026\/03\/csoportkep-2.jpg 1758w, https:\/\/semmelweis.hu\/immun-patofiziologia\/files\/2026\/03\/csoportkep-2-300x210.jpg 300w, https:\/\/semmelweis.hu\/immun-patofiziologia\/files\/2026\/03\/csoportkep-2-1024x718.jpg 1024w, https:\/\/semmelweis.hu\/immun-patofiziologia\/files\/2026\/03\/csoportkep-2-768x538.jpg 768w, https:\/\/semmelweis.hu\/immun-patofiziologia\/files\/2026\/03\/csoportkep-2-1536x1076.jpg 1536w, https:\/\/semmelweis.hu\/immun-patofiziologia\/files\/2026\/03\/csoportkep-2-753x528.jpg 753w\" sizes=\"auto, (max-width: 630px) 100vw, 630px\" \/><\/a><\/h2>\n<pre style=\"text-align: center\"><span style=\"font-size: 14px;font-family: 'pt serif'\">Zolt\u00e1n Ko\u00f3s, D\u00e1niel B\u00f3csi, Qusay Abdalla, Hakim Al-murshidy, Ebsa Ahmed, Mingming He, P\u00e9ter Hamar <\/span>\r\n<span style=\"font-size: 14px;font-family: 'pt serif'\">Csaba Schvarcz, Yibo Gu, Mohamed Elsalahaty, Evan Santo<\/span>\r\n<span style=\"font-size: 14px;font-family: 'pt serif'\">Eslam Abdalalem<\/span><\/pre>\n<h2>Previous filds of research:<\/h2>\n<p><span data-olk-copy-source=\"MessageBody\">After co-developing the rodent moduelated electro-hyperthermia device (LabEhy) we demonstrated possible repurposing of several basic drugs for enhancing the theraopeutic effects of cancer hyperthermia such as digoxin, COX-2 inhibition, ivermectin meanwhile demonstrating substantial effects of hypoxia signaling, non-steroid- and heat-shock pathways in cancer progression.<\/span><\/p>\n<p>Initially we investigated the pathomechanism of rejection following kidney transplantation in a rat model. The function of the transplanted kidney is basically determined by the ischemic and immunological damaging factors suffered during the transplant, result in renal fibrosis which is the common route of chronic kidney damage. We were the first to use RNA interference in the kidney for in-vivo gene silencing. In the present research, we focus on the pathomechanism of fibrosis induced by renal ischemia.<\/p>\n<h2>Contact:<\/h2>\n<p>SU-Medical Faculty, <span data-olk-copy-source=\"MessageBody\">Institute of Clinical Pathophysiology<span style=\"font-size: 10pt\"> (former name: Institute of Translational Medicine)<\/span><\/span><br \/>\n1094 Budapest, T\u0171zolt\u00f3 utca 37-49<br \/>\nMobil: (+36 20) 825 9751<br \/>\nFax: (+36 20) 825 6507<br \/>\nemail: hamar.peter@semmelweis.hu<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Current field of research: The role of acute phase proteins focusing on fibrinogen in the pathomechanism and the treatment of breast cancer with modulated electro-hypertemia and of renal fibrosis induced by acute ischemic kidney damage. Sz\u00e9n\u00e1si G\u00e1bor, Yibo Gu, B\u00f3csi D\u00e1niel, Qusay Abdalla, Eslam Abdalalem, Mohamed Elsalahaty, Hakim Al-murshidy, Hamar P\u00e9ter, Evan Santo, Ebsa Ahmed, &hellip;<\/p>\n","protected":false},"author":162,"featured_media":0,"parent":0,"menu_order":1,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"footnotes":""},"categories":[],"tags":[],"class_list":["post-369","page","type-page","status-publish","hentry"],"acf":[],"_links":{"self":[{"href":"https:\/\/semmelweis.hu\/immun-patofiziologia\/wp-json\/wp\/v2\/pages\/369","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/semmelweis.hu\/immun-patofiziologia\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/semmelweis.hu\/immun-patofiziologia\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/semmelweis.hu\/immun-patofiziologia\/wp-json\/wp\/v2\/users\/162"}],"replies":[{"embeddable":true,"href":"https:\/\/semmelweis.hu\/immun-patofiziologia\/wp-json\/wp\/v2\/comments?post=369"}],"version-history":[{"count":10,"href":"https:\/\/semmelweis.hu\/immun-patofiziologia\/wp-json\/wp\/v2\/pages\/369\/revisions"}],"predecessor-version":[{"id":2421,"href":"https:\/\/semmelweis.hu\/immun-patofiziologia\/wp-json\/wp\/v2\/pages\/369\/revisions\/2421"}],"wp:attachment":[{"href":"https:\/\/semmelweis.hu\/immun-patofiziologia\/wp-json\/wp\/v2\/media?parent=369"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/semmelweis.hu\/immun-patofiziologia\/wp-json\/wp\/v2\/categories?post=369"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/semmelweis.hu\/immun-patofiziologia\/wp-json\/wp\/v2\/tags?post=369"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}