{"id":13,"date":"2013-05-16T19:06:40","date_gmt":"2012-09-11T13:40:47","guid":{"rendered":"http:\/\/semmelweis-egyetem.hu\/onkoterapiai-tanszek\/?page_id=5"},"modified":"2026-03-11T15:34:56","modified_gmt":"2026-03-11T14:34:56","slug":"altalanos-informaciok","status":"publish","type":"page","link":"https:\/\/semmelweis.hu\/immun-patofiziologia\/","title":{"rendered":"Az Immun-patofiziol\u00f3giai Csoport bemutat\u00e1sa"},"content":{"rendered":"
\n

Jelenlegi kutat\u00e1si ter\u00fclet\u00fcnk:<\/h2>\n

Az akut f\u00e1zis feh\u00e9rj\u00e9k, k\u00fcl\u00f6n\u00f6sen a fibrinog\u00e9n szerep\u00e9nek vizsg\u00e1lata az eml\u0151r\u00e1k patomechanizmusban \u00e9s modul\u00e1lt elektro-hipertermi\u00e1val t\u00f6rt\u00e9n\u0151 kezel\u00e9s\u00e9ben, valamint az akut iszk\u00e9mi\u00e1s vesek\u00e1rosod\u00e1s induk\u00e1lta vesefibr\u00f3zisban.<\/p>\n<\/div>\n

\"\"<\/p>\n

Sz\u00e9n\u00e1si G\u00e1bor, Yibo Gu, B\u00f3csi D\u00e1niel, Qusay Abdalla, Eslam Abdalalem, Mohamed Elsalahaty, Hakim Al-murshidy, Hamar P\u00e9ter, Evan Santo, Ebsa Ahmed, Mingming He, Ko\u00f3s Zolt\u00e1n<\/span><\/p>\n

\"\"<\/a><\/h2>\n
Ko\u00f3s Zolt\u00e1n, B\u00f3csi D\u00e1niel, Qusay Abdalla, Hakim Al-murshidy, Ebsa Ahmed, Mingming He, Hamar P\u00e9ter <\/span>\r\nSchvarcz Csaba, Yibo Gu, Mohamed Elsalahaty, Evan Santo<\/span>\r\nEslam Abdalalem\r\n<\/span><\/pre>\n
Kor\u00e1bbi kutat\u00e1si ter\u00fclteteink:<\/h2>\n
A r\u00e1gcs\u00e1l\u00f3kon alkalmazhat\u00f3 modul\u00e1lt elektro-hiperthermia berendez\u00e9s (LabEhy) t\u00e1rsfejleszt\u00e9se ut\u00e1n megvizsg\u00e1ltuk t\u00f6bb alapvet\u0151 gy\u00f3gyszer alkalmazhat\u00f3s\u00e1g\u00e1nak \u00fajszer\u0171 lehet\u0151s\u00e9geit a r\u00e1k hipertermi\u00e1s kezel\u00e9s\u00e9nek jav\u00edt\u00e1sa \u00e9rdek\u00e9ben, p\u00e9ld\u00e1ul digoxin, COX-2 g\u00e1tl\u00f3 szer, ivermectin, mik\u00f6zben vizsg\u00e1ltuk alapvet\u0151 hipoxia-, nem-szteroid- \u00e9s h\u0151-sokk jel\u00e1tviteli utak hat\u00e1s\u00e1t a r\u00e1k progresszi\u00f3j\u00e1ban.<\/span><\/p>\n
Kezdetben a vese\u00e1t\u00fcltet\u00e9st k\u00f6vet\u0151 kil\u00f6k\u0151d\u00e9si reakci\u00f3 patomechanizmus\u00e1t vizsg\u00e1ltuk patk\u00e1nymodellen. Az \u00e1t\u00fcltetett vese m\u0171k\u00f6d\u00e9s\u00e9t alapvet\u0151en meghat\u00e1rozz\u00e1k az \u00e1t\u00fcltet\u00e9s sor\u00e1n elszenvedett iszk\u00e9mi\u00e1s \u00e9s immunol\u00f3giai k\u00e1ros\u00edt\u00f3 t\u00e9nyez\u0151k melyek eredm\u00e9nyek\u00e9nt kialakul\u00f3 vese-fibr\u00f3zis a kr\u00f3nikus vesek\u00e1rosod\u00e1s \u00e1ltal\u00e1nos \u00fatja. Els\u0151k\u00e9nt alkalmaztunk RNS interferenci\u00e1t a ves\u00e9ben in-vivo g\u00e9ncsendes\u00edt\u00e9sre. Jelen kutat\u00e1sainkban a vese iszk\u00e9mia induk\u00e1lta fibr\u00f3zis patomechanizmus\u00e1ra f\u00f3kusz\u00e1lunk.<\/p>\n
El\u00e9rhet\u0151s\u00e9g:<\/h2>\n
Semmelweis Egyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar, Klinikai<\/span> K\u00f3r\u00e9lettani Int\u00e9zet (kor\u00e1bbi neve: Transzl\u00e1ci\u00f3s Medicina Int\u00e9zet)<\/span>
\n1094 Budapest, T\u0171zolt\u00f3 utca 37-49
\nMobil: (+36 20) 825 9751
\nFax: (+36 20) 825 6507
\nemail: hamar.peter@semmelweis.hu<\/p>\n
\u00a0<\/div>\n","protected":false},"excerpt":{"rendered":"
Jelenlegi kutat\u00e1si ter\u00fclet\u00fcnk: Az akut f\u00e1zis feh\u00e9rj\u00e9k, k\u00fcl\u00f6n\u00f6sen a fibrinog\u00e9n szerep\u00e9nek vizsg\u00e1lata az eml\u0151r\u00e1k patomechanizmusban \u00e9s modul\u00e1lt elektro-hipertermi\u00e1val t\u00f6rt\u00e9n\u0151 kezel\u00e9s\u00e9ben, valamint az akut iszk\u00e9mi\u00e1s vesek\u00e1rosod\u00e1s induk\u00e1lta vesefibr\u00f3zisban. Sz\u00e9n\u00e1si G\u00e1bor, Yibo Gu, B\u00f3csi D\u00e1niel, Qusay Abdalla, Eslam Abdalalem, Mohamed Elsalahaty, Hakim Al-murshidy, Hamar P\u00e9ter, Evan Santo, Ebsa Ahmed, Mingming He, Ko\u00f3s Zolt\u00e1n <\/a> Ko\u00f3s Zolt\u00e1n, B\u00f3csi D\u00e1niel, …<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":1,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"footnotes":""},"categories":[],"tags":[],"class_list":["post-13","page","type-page","status-publish","hentry"],"acf":[],"_links":{"self":[{"href":"https:\/\/semmelweis.hu\/immun-patofiziologia\/wp-json\/wp\/v2\/pages\/13","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/semmelweis.hu\/immun-patofiziologia\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/semmelweis.hu\/immun-patofiziologia\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/semmelweis.hu\/immun-patofiziologia\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/semmelweis.hu\/immun-patofiziologia\/wp-json\/wp\/v2\/comments?post=13"}],"version-history":[{"count":11,"href":"https:\/\/semmelweis.hu\/immun-patofiziologia\/wp-json\/wp\/v2\/pages\/13\/revisions"}],"predecessor-version":[{"id":2420,"href":"https:\/\/semmelweis.hu\/immun-patofiziologia\/wp-json\/wp\/v2\/pages\/13\/revisions\/2420"}],"wp:attachment":[{"href":"https:\/\/semmelweis.hu\/immun-patofiziologia\/wp-json\/wp\/v2\/media?parent=13"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/semmelweis.hu\/immun-patofiziologia\/wp-json\/wp\/v2\/categories?post=13"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/semmelweis.hu\/immun-patofiziologia\/wp-json\/wp\/v2\/tags?post=13"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}