{"id":1436,"date":"2025-06-10T14:38:35","date_gmt":"2025-06-10T12:38:35","guid":{"rendered":"https:\/\/semmelweis.hu\/hcemm-neurobiology\/?p=1436"},"modified":"2025-06-10T14:39:51","modified_gmt":"2025-06-10T12:39:51","slug":"new-paper-out-in-aging-cell","status":"publish","type":"post","link":"https:\/\/semmelweis.hu\/hcemm-neurobiology\/2025\/06\/10\/new-paper-out-in-aging-cell\/","title":{"rendered":"New paper out in Aging Cell!"},"content":{"rendered":"<p class=\"ds-markdown-paragraph\" style=\"text-align: justify\">Our lab contributed to a new study published in\u00a0<em>Aging Cell<\/em>\u00a0investigating how cardiorespiratory fitness influences epigenetic aging across different organs. Using a rat model of high- and low-capacity runners, the research found:<\/p>\n<p class=\"ds-markdown-paragraph\" style=\"text-align: justify\">\u2022 Significant organ-specific differences in DNA methylation patterns related to fitness<br \/>\n\u2022 The soleus muscle showed the most pronounced epigenetic changes<br \/>\n\u2022 Seven genes displayed consistent methylation changes across all organs studied<br \/>\n\u2022 Epigenetic aging rates varied substantially between tissues<\/p>\n<p class=\"ds-markdown-paragraph\" style=\"text-align: justify\">The findings highlight the complex relationship between exercise, epigenetics and aging, emphasizing the importance of organ-specific approaches in aging research.<\/p>\n<p class=\"ds-markdown-paragraph\" style=\"text-align: justify\">We&#8217;re grateful to have collaborated on this important work!<\/p>\n<p>\ud83d\udd17\u00a0<strong>Read the study:<\/strong> <a href=\"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/acel.70110\" target=\"_blank\" rel=\"noopener\">https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/acel.70110<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Our lab contributed to a new study published in\u00a0Aging Cell\u00a0investigating how cardiorespiratory fitness influences epigenetic aging across different organs. Using a rat model of high- and low-capacity runners, the research found: \u2022 Significant organ-specific differences in DNA methylation patterns related to fitness \u2022 The soleus muscle showed the most pronounced epigenetic changes \u2022 Seven genes &hellip;<\/p>\n","protected":false},"author":101875,"featured_media":1438,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[1],"tags":[],"class_list":["post-1436","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-news"],"acf":[],"_links":{"self":[{"href":"https:\/\/semmelweis.hu\/hcemm-neurobiology\/wp-json\/wp\/v2\/posts\/1436","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/semmelweis.hu\/hcemm-neurobiology\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/semmelweis.hu\/hcemm-neurobiology\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/semmelweis.hu\/hcemm-neurobiology\/wp-json\/wp\/v2\/users\/101875"}],"replies":[{"embeddable":true,"href":"https:\/\/semmelweis.hu\/hcemm-neurobiology\/wp-json\/wp\/v2\/comments?post=1436"}],"version-history":[{"count":1,"href":"https:\/\/semmelweis.hu\/hcemm-neurobiology\/wp-json\/wp\/v2\/posts\/1436\/revisions"}],"predecessor-version":[{"id":1439,"href":"https:\/\/semmelweis.hu\/hcemm-neurobiology\/wp-json\/wp\/v2\/posts\/1436\/revisions\/1439"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/semmelweis.hu\/hcemm-neurobiology\/wp-json\/wp\/v2\/media\/1438"}],"wp:attachment":[{"href":"https:\/\/semmelweis.hu\/hcemm-neurobiology\/wp-json\/wp\/v2\/media?parent=1436"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/semmelweis.hu\/hcemm-neurobiology\/wp-json\/wp\/v2\/categories?post=1436"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/semmelweis.hu\/hcemm-neurobiology\/wp-json\/wp\/v2\/tags?post=1436"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}