{"id":48688,"date":"2015-05-15T17:51:17","date_gmt":"2015-05-15T15:51:17","guid":{"rendered":"http:\/\/semmelweis.hu\/hbtb\/?page_id=48688"},"modified":"2025-09-19T11:22:35","modified_gmt":"2025-09-19T09:22:35","slug":"nap-project","status":"publish","type":"page","link":"https:\/\/semmelweis.hu\/hbtb\/nap-project\/","title":{"rendered":"NAP project"},"content":{"rendered":"<p style=\"text-align: justify\"><strong>Participation of the HBTB in the NAP project<a href=\"https:\/\/semmelweis.hu\/hbtb\/files\/2015\/05\/NAP.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"alignright size-thumbnail wp-image-48689\" src=\"https:\/\/semmelweis.hu\/hbtb\/files\/2015\/05\/NAP-150x150.jpg\" alt=\"NAP\" width=\"150\" height=\"150\" srcset=\"https:\/\/semmelweis.hu\/hbtb\/files\/2015\/05\/NAP-150x150.jpg 150w, https:\/\/semmelweis.hu\/hbtb\/files\/2015\/05\/NAP-90x90.jpg 90w\" sizes=\"auto, (max-width: 150px) 100vw, 150px\" \/><\/a><\/strong><\/p>\n<p style=\"text-align: justify\">Hungary has launched a <strong>National Brain Research Program<\/strong> (Nemzeti Agykutat\u00e1si Program = NAP) with a government subsidy to explore the most frequent diseases of the brain, including depression, migraine, cerebral metastases, Alzheimer&#8217;s and Parkinson&#8217;s disease.<\/p>\n<p style=\"text-align: justify\"><strong>Microdissection Researh Group within the HBTB: SE-NAP &#8211; Human Brain Tissue Bank Microdissection Laboratory<\/strong><\/p>\n<p style=\"text-align: justify\">Head: Eva Dobolyine Renner, PhD<\/p>\n<p>&nbsp;<\/p>\n<p style=\"text-align: justify\"><strong>Specific aims for the participation:<\/strong><\/p>\n<ul style=\"text-align: justify\">\n<li>Keep safety running of the activity of the HBTB requires an increase in human sources in the HBTB.<\/li>\n<li>Extension of the donor program, the microdissection capacity and the scientific collaboration activity with Hungarian research laboratories participating in the NAP project (providing reasonable number of microdissected human brain samples) suitable for neurochemical, molecular biological, proteomic and genetic studies.<\/li>\n<li>Start with the Lenhoss\u00e9k program in collaboration with the Department of Neurology, Debrecen University for country-wide collections of human brains for biological\/medical research purposes. Collection of brains from persons died in neurodegenerative or psychiatric disorders is special important.<\/li>\n<li>Increasing the repertoire of the HBTB by further selection of cortical subdivisions for microdissection. Recently, basic and clinical neuroscience information increased rapidly about the topographically and functionally characterized human cortical areas. However, this extension of the microdissection and banking may require an increase in human sources in the HBTB.<\/li>\n<li>The next years, teach and train a postdoctoral or young scientist in the human microdissection technique is vital for the future of the HBTB.<\/li>\n<\/ul>\n<p style=\"text-align: justify\"><span style=\"color: #333333\"><strong>Publications<\/strong><\/span><\/p>\n<ol>\n<li style=\"text-align: justify\"><span style=\"color: #000000\">Fuxe K, Borroto-Escuela DO, Romero-Fernandez W, Palkovits M, Tarakanov AO, Ciruela F &amp; Agnati LF (2014) Moonlighting proteins and protein-protein interactions as neurotherapeutic targets in the G protein-coupled receptor field, <em>Neuropsychopharmacology<\/em> 39: 131-155. \u00a0IF: 7.048<\/span><\/li>\n<li style=\"text-align: justify\"><span style=\"color: #000000\">Du L, Merali Z, Poulter MO, Palkovits M, Faludi G &amp; Anisman H (2014) Catechol-O-methyltransferase Val158Met polymorphism and altered COMT gene expression in the prefrontal cortex of suicide brains, <em>Prog Neuropsychopharmacol Biol Psychiatry<\/em> 50: 178-183. \u00a0IF: 3.689<\/span><\/li>\n<li style=\"text-align: justify\"><span style=\"color: #000000\">Dobolyi A, Ostergaard E, Bag\u00f3 AG, D\u00f3czi T, Palkovits M, G\u00e1l A, Moln\u00e1r MJ, Adam-Vizi V &amp; Chinopoulos C (2015) Exclusive neuronal expression of SUCLA2 in the human brain, <em>Brain Struct Funct<\/em> 220: 135-151. \u00a0IF: 5.811<\/span><\/li>\n<li style=\"text-align: justify\"><span style=\"color: #000000\">Dobolyi A, Bag\u00f3 AG, G\u00e1l A, Moln\u00e1r MJ, Palkovits M, Adam-Vizi V &amp; Chinopoulos C (2015) Localization of SUCLA2 and SUCLG2 subunits of succinyl CoA ligase within the cerebral cortex suggests the absence of matrix substrate-level phosphorylation in glial cells of the human brain, <em>J Bioenerg Biomembr<\/em> 47: 33-41. \u00a0IF: 2.080<\/span><\/li>\n<li style=\"text-align: justify\"><span style=\"color: #000000\">\u00c1dori C, Gl\u00fcck L, Barde S, Yoshitake T, Kovacs GG, Mulder J, Magl\u00f3czky Z, Havas L, B\u00f6lcskei K, Mitsios N, Uhl\u00e9n M, Szolcs\u00e1nyi J, Kehr J, R\u00f6nnb\u00e4ck A, Schwartz T, Rehfeld JF, Harkany T, Palkovits M, Schulz S &amp; H\u00f6kfelt T (2015) Critical role of somatostatin receptor 2 in the vulnerability of the central noradrenergic system: new aspects on Alzheimer&#8217;s disease, <em>Acta Neuropathol<\/em> 129: 541-563. \u00a0IF: 11.360<\/span><\/li>\n<li style=\"text-align: justify\"><span style=\"color: #000000\">Durrenberger PF, Fernando FS, Kashefi SN, Bonnert TP, Seilhean D, Nait-Oumesmar B, Schmitt A, Gebicke-Haerter PJ, Falkai P, Gr\u00fcnblatt E, Palkovits M, Arzberger T, Kretzschmar H, Dexter DT &amp; Reynolds R (2015) Common mechanisms in neurodegeneration and neuroinflammation: a BrainNet Europe gene expression microarray study, <em>J Neural Transm<\/em> 122: 1055-1068. \u00a0IF: 2.587<\/span><\/li>\n<li style=\"text-align: justify\"><span style=\"color: #000000\">Amy M, Staehlin O, Ren\u00e9 F, Blasco H, Marouillat S, Daoud H, Vourc\u2019h P, Gordon PH, Camu W, Corcia P, Loeffler JP, Palkovits M, Sommer WH &amp; Andres CR (2015) A common functional allele of the Nogo receptor gene, reticulon 4 receptor (RTN4R), is associated with sporadic amyotrophic lateral sclerosis in a French population, <em>Amyotroph Lat Scl Fr <\/em>16: 490-496. IF: 2.677<\/span><\/li>\n<li style=\"text-align: justify\"><span style=\"color: #000000\">Hayley S, Du L, Litteljohn D, Palkovits M, Faludi G, Merali Z, Poulter MO &amp; Anisman H (2015) Gender and brain regions specific differences in brain derived neurotrophic factor protein levels of depressed individuals who died through suicide, <em>Neurosci Lett<\/em> 600: 12-16. IF: 2.107<\/span><\/li>\n<li style=\"text-align: justify\"><span style=\"color: #000000\">Aschrafi A, Verheijen JM, Gordebeke PM, Olde Loohuis NF, Menting K, Jager A, Palkovits M, Geenen B, Kos A, Martens GJ, Glennon JC, Kaplan BB, Gaszner B &amp; Kozicz T (2016) MicroRNA-326 acts as a molecular switch in the regulation of midbrain urocortin 1 expression, <em>J Psychiatry Neurosci<\/em> 41: 342-353. IF:\u00a05.165<\/span><\/li>\n<li style=\"text-align: justify\"><span style=\"color: #000000\">Barde S, R\u00fcegg J, Prud\u2019homme J, Ekstr\u00f6m TJ, Palkovits M, Turecki G, Bagdy G, Ihnatko R, Theodorsson E, Juhasz G, Diaz-Heijtz R, Mechawar N &amp; H\u00f6kfelt TGM (2016) Alterations in the neuropeptide galanin system in major depressive disorder involve levels of transcripts, methylation, and peptide, <em>P Natl Acad Sci USA <\/em>113: E8472-E8481. IF:\u00a09.661<\/span><\/li>\n<li style=\"text-align: justify\"><span style=\"color: #000000\">Roy B, Wang Q, Palkovits M, Faludi G &amp; Dwivedi Y (2017) Molecular insights of dysregulated microRNA network in the locus coeruleus of depressed suicide complements, <em>Sci Rep<\/em> 7: 4387. IF: 4.122<\/span><\/li>\n<li style=\"text-align: justify\"><span style=\"color: #000000\">Tomb\u00e1cz D, Mar\u00f3ti Z, Kalm\u00e1r T, Csabai Zs, Bal\u00e1zs Zs, Takahashi S, Palkovits M, Snyder M &amp; Boldogk\u0151i Zs (2017) High-coverage whole-exome sequencing identifies candidate genes for suicide in victims with major depressive disorder, <em>Sci Rep<\/em> 7: 7106. IF: 4.122<\/span><\/li>\n<li style=\"text-align: justify\"><span style=\"color: #000000\">Albert M, Barrantes-Freer A, Lohrberg M, Antel JP, Prineas JW, Palkovits M, Wolff JR, Br\u00fcck W &amp; Stadelmann C (2017) Synaptic pathology in the cerebellar dentate nucleus in chronic multiple sclerosis, <em>Brain Pathol<\/em> 27: 737-747. IF: 6.187<\/span><\/li>\n<li style=\"text-align: justify\"><span style=\"color: #000000\">P\u00e1lv\u00f6lgyi A, Simpson J, Bodn\u00e1r I, B\u00edr\u00f3 J, Palkovits M, Radovits T, Skehel P &amp; Antoni FA (2018) Auto-inhibition of adenylyl cyclase 9 (AC9) by an isoform-specific motif in the carboxyl-terminal region, <em>Cell Signal<\/em> 51: 266-275. IF: 3.388<\/span><\/li>\n<li style=\"text-align: justify\"><span style=\"color: #000000\">Martin NA, Nawrocki A, Molnar V, Elkjaer ML, Thygesen EK, Palkovits M, Acs P, Sejbaek T, Nielsen HH, Hegedus Z, Sellebjerg F, Molnar T, Barbosa EGV, Alcaraz N, Gallyas F Jr, Svenningsen AF, Baumbach J, Lassmann H, Larsen MR &amp; Illes Z (2018) Orthologous proteins of experimental de- and remyelination are differentially regulated in the CSF proteome of multiple sclerosis subtypes. <em>PLoS One<\/em> 13: e0202530. IF: 2.776<\/span><\/li>\n<li>\n<div style=\"text-align: justify\"><span style=\"color: #000000\">Alp\u00e1r A, Zahola P, Hanics J, Hevesi Z, Korchynska S, Benevento M, Pifl C, Zachar G, Perugini J, Severi I, Leitgeb P, Bakker J, Miklosi AG, Tretiakov E, Keimpema E, Arque G, Tasan RO, Sperk G, Malenczyk K, M\u00e1t\u00e9 Z, Erd\u00e9lyi F, Szab\u00f3 G, Lubec G, Palkovits M, Giordano A, H\u00f6kfelt TG, Romanov RA, Horvath TL &amp; Harkany T (2018) Hypothalamic CNTF volume transmission shapes cortical noradrenergic excitability upon acute stress. <em>EMBO J<\/em> 37: e100087.\u00a0IF: 11.227<\/span><\/div>\n<\/li>\n<li style=\"text-align: justify\"><span style=\"color: #000000\">Tomb\u00e1cz D, Mar\u00f3ti Z, Kalm\u00e1r T, Palkovits M, Snyder M &amp; Boldogk\u0151i Z (2019) Whole-exome sequencing data of suicide victims who had suffered from major depressive disorder, <em>Sci Data<\/em> 6: 190010. IF: 5.541<\/span><\/li>\n<li style=\"text-align: justify\"><span style=\"color: #000000\">Mendon\u00e7a CF, Kuras M, Nogueira FCS, Pl\u00e1 I, Hortob\u00e1gyi T, Csiba L, Palkovits M, Renner \u00c9, D\u00f6me P, Marko-Varga G, Domont GB &amp; Rezeli M (2019) Proteomic signatures of brain regions affected by tau pathology in early and late stages of Alzheimer&#8217;s disease, <em>Neurobiol Dis<\/em> 130: 104509. IF: 5.332<\/span><\/li>\n<li style=\"text-align: justify\"><span style=\"color: #000000\">Kardos J, Dobolyi \u00c1, Szab\u00f3 Z, Simon \u00c1, Lourmet G, Palkovits M &amp; H\u00e9ja L (2019) Molecular plasticity of the nucleus accumbens revisited-astrocytic waves shall rise, <em>Mol Neurobiol<\/em> 56: 7950-7965.\u00a0IF: 4.500<\/span><\/li>\n<li style=\"text-align: justify\">Hertz H, Carstensen MB, Bering T, Rohde K, M\u00f8ller M, Granau AM, Coon SL, Klein DC, Rath MF (2020) The Lhx4 homeobox transcript in the rat pineal gland: Adrenergic regulation and impact on transcripts encoding melatonin-synthesizing enzymes, <em>J Pineal Res<\/em> 68: e12616. IF: 13.007<\/li>\n<li style=\"text-align: justify\"><span style=\"color: #000000\">Carstensen MB, Hertz H, Bering T, M\u00f8ller M, Rohde K, Klein DC, Coon SL &amp; Rath MF (2020) Circadian regulation and molecular role of the Bsx homeobox gene in the adult pineal gland, <em>J Pineal Res <\/em>68: e12629. IF: 13.007<\/span><\/li>\n<li style=\"text-align: justify\"><span style=\"color: #000000\">Dobolyi A, Bago A, Palkovits M, Nemeria NS, Jordan F, Doczi J, Ambrus A, Adam-Vizi V &amp; Chinopoulos C (2020) Exclusive neuronal detection of KGDHC-specific subunits in the adult human brain cortex despite pancellular protein lysine succinylation, <em>Brain Struct Funct<\/em> 225: 639-667. IF: 3.270<\/span><\/li>\n<li style=\"text-align: justify\"><span style=\"color: #000000\">Kecsk\u00e9s A, Poh\u00f3czky K, Kecsk\u00e9s M, Varga ZV, Kormos V, Sz\u0151ke \u00c9, Henn-Mike N, Feh\u00e9r M, Kun J, Gyenesei A, Renner \u00c9, Palkovits M, Ferdinandy P, \u00c1brah\u00e1m IM, Gaszner B &amp; Helyes Zs (2020) Characterization of neurons expressing the novel analgesic drug target somatostatin receptor 4 in mouse and human brains, <em>Int J Mol Sci<\/em> 21: 7788. IF: 5.923<\/span><\/li>\n<li style=\"text-align: justify\"><span style=\"color: #000000\">Hevesi Z, Zelena D, Romanov RA, Hanics J, Ign\u00e1cz A, Zambon A, Pollak DD, Lendvai D, Schlett K, Palkovits M, Harkany T, H\u00f6kfelt TGM &amp; Alp\u00e1r A (2021) Secretagogin marks amygdaloid PKC\u03b4 interneurons and modulates NMDA receptor availability, <em>Proc Natl Acad Sci U S A<\/em> 118: e1921123118. IF: 12.779<\/span><\/li>\n<li style=\"text-align: justify\">Vel\u00e1squez E, Szeitz B, Gil J, Rodriguez J, Palkovits M, Renner \u00c9, Hortob\u00e1gyi T, D\u00f6me P, Nogueira FCS, Marko-Varga G, Domont GB &amp; Rezeli M (2021) Topological dissection of proteomic changes linked to the limbic stage of Alzheimer\u2019s disease, <em>Front Immunol<\/em> 12: 750665. IF: 8.787<\/li>\n<li>Samard\u017eija B, Pave\u0161i\u0107 Radonja A, Zaharija B, Bergman M, Renner \u00c9, Palkovits M, Rube\u0161a G &amp; Bradshaw NJ (2021) Protein aggregation of NPAS3, implicated in mental illness, is not limited to the V304I mutation, <em>J Pers Med<\/em> 11: 1070. IF: 3.508<\/li>\n<li style=\"text-align: justify\">Vitale-Cross L, Szalayova I, Scoggins A, Palkovits M &amp; Mezey E (2022) SARS-CoV-2 entry sites are present in all structural elements of the human glossopharyngeal and vagal nerves: Clinical implications, <em>eBioMedicine<\/em> 78: 103981. IF: 11.1<\/li>\n<li style=\"text-align: justify\">Kormos V, Kecsk\u00e9s A, Farkas J, Gaszner T, Csernus V, Alomari A, Heged\u00fcs D, Renner \u00c9, Palkovits M, Zelena D, Helyes Z, Pint\u00e9r E &amp; Gaszner B (2022) Peptidergic neurons of the Edinger-Westphal nucleus express TRPA1 ion channel that is downregulated both upon chronic variable mild stress in male mice and in humans who died by suicide, <em>J Psychiatry Neurosci<\/em> 47: E162-E175. IF: 4.3<\/li>\n<li style=\"text-align: justify\">D\u00f3ra F, Renner \u00c9, Keller D, Palkovits M &amp; Dobolyi \u00c1 (2022) Transcriptome profiling of the dorsomedial prefrontal cortex in suicide victims, <em>Int J Mol Sci<\/em> 23: 7067. IF: 5.6<\/li>\n<li style=\"text-align: justify\">Hardwick SA, Hu W, Joglekar A, Fan L, Collier PG, Foord C, Balacco J, Lanjewar S, Sampson MM, Koopmans F, Prjibelski AD, Mikheenko A, Belchikov N, Jarroux J, Lucas AB, Palkovits M, Luo W, Milner TA, Ndhlovu LC, Smit AB, Trojanowski JQ, Lee VMY, Fedrigo O, Sloan SA, Tomb\u00e1cz D, Ross ME, Jarvis E, Boldogk\u0151i Z, Gan L &amp; Tilgner HU (2022) Single-nuclei isoform RNA sequencing unlocks barcoded exon connectivity in frozen brain tissue, <em>Nat Biotechnol<\/em> 40: 1082-1092. IF: 46.9<\/li>\n<li style=\"text-align: justify\">Zhong W, Barde S, Mitsios N, Adori C, Oksvold P, Feilitzen KV, O&#8217;Leary L, Csiba L, Hortob\u00e1gyi T, Szocsics P, Mechawar N, Magl\u00f3czky Z, Renner \u00c9, Palkovits M, Uhl\u00e9n M, Mulder J &amp; H\u00f6kfelt T (2022) The neuropeptide landscape of human prefrontal cortex, <em>Proc Natl Acad Sci U S A<\/em> 119: e2123146119. IF: 11.1<\/li>\n<li style=\"text-align: justify\">Keller D, L\u00e1ng T, Cserven\u00e1k M, Puska G, Barna J, Csillag V, Farkas I, Zelena D, D\u00f3ra F,\u00a0 K\u00fcppers S, Barteczko L, Usdin TB, Palkovits M, Hasan MT, Grinevich V &amp; Dobolyi A (2022) A thalamo-preoptic pathway promotes social grooming in rodents, <em>Curr Biol<\/em> 32: 4593-4606. IF: 9.2<\/li>\n<li style=\"text-align: justify\">Renner \u00c9, D\u00f3ra F, Oszwald E, Dobolyi \u00c1 &amp; Palkovits M (2022) Elevated glucagon-like peptide-1 receptor level in the paraventricular hypothalamic nucleus of type 2 diabetes mellitus patients, <em>Int J Mol Sci<\/em> 23: 15945. IF: 5.6<\/li>\n<li style=\"text-align: justify\">Kov\u00e1cs T, Sziny\u00e1kovics J, Billes V, Mur\u00e1nyi G, Varga VB, Bjelik A, L\u00e9gr\u00e1di \u00c1, Szab\u00f3 M, S\u00e1ndor S, Kubinyi E, Szekeres-Paracky C, Szocsics P, L\u0151ke J, Mulder J, Guly\u00e1s B, Renner \u00c9, Palkovits M, Gulya K, Magl\u00f3czky Z &amp; Vellai T (2022) A conserved MTMR lipid phosphatase increasingly suppresses autophagy in brain neurons during aging, <em>Sci Rep<\/em> 12: 21817. IF: 4.6<\/li>\n<li style=\"text-align: justify\">Vas S, Papp RS, K\u00f6ncz\u00f6l K, Bog\u00e1thy E, Papp N, \u00c1dori C, Durst M, S\u00edpos K, Ocskay K, Farkas I, B\u00e1lint F, Ferenci S, T\u00f6r\u00f6k B, Kov\u00e1cs A, Szab\u00f3 E, Zelena D, Kov\u00e1cs KJ, F\u00f6ldes A, Kat\u00f3 E, K\u00f6les L, Bagdy G, Palkovits M &amp; T\u00f3th ZE (2023) Prolactin-releasing peptide contributes to stress-related mood disorders and inhibits sleep\/mood regulatory melanin-concentrating hormone neurons in rats, <em>J Neurosci<\/em> 43: 846-862. IF: 4.4<\/li>\n<li style=\"text-align: justify\">Samard\u017eija B, Jukovi\u0107 M, Zaharija B, Renner \u00c9, Palkovits M &amp; Bradshaw NJ (2023) Co-aggregation and parallel aggregation of specific proteins in major mental illness, <em>Cells<\/em> 12: 1848. IF: 5.1<\/li>\n<li style=\"text-align: justify\">Borb\u00e9ly \u00c9, Kecsk\u00e9s A, Kun J, Kepe E, F\u00fcl\u00f6p B, Kov\u00e1cs-Rozmer K, Scheich B, Renner \u00c9, Palkovits M &amp; Helyes Z (2023) Hemokinin-1 is a mediator of chronic restraint stress-induced pain, <em>Sci Rep<\/em> 13: 20030. IF: 3.8<\/li>\n<li style=\"text-align: justify\">Barde S, Aguila J, Zhong W, Solarz A, Mei I, Prud&#8217;homme J, Palkovits M, Turecki G, Mulder J, Uhl\u00e9n M, Nagy C, Mechawar N, Hedlund E &amp; H\u00f6kfelt T (2024) Substance P, NPY, CCK and their receptors in five brain regions in major depressive disorder with transcriptomic analysis of locus coeruleus neurons, <em>Eur Neuropsychopharmacol<\/em> 78: 54-63. IF: 6.7<\/li>\n<li style=\"text-align: justify\">Sepp M, Leiss K, Murat F, Okonechnikov K, Joshi P, Leushkin E, Sp\u00e4nig L, Mbengue N, Schneider C, Schmidt J, Trost N, Schauer M, Khaitovich P, Lisgo S, Palkovits M, Giere P, Kutscher LM, Anders S, Cardoso-Moreira M, Sarropoulos I, Pfister SM &amp; Kaessmann H (2024) Cellular development and evolution of the mammalian cerebellum, <em>Nature<\/em> 625: 788-796. IF: 48.5<\/li>\n<li style=\"text-align: justify\">Dobolyi A, Cserven\u00e1k M, Bag\u00f3 AG, Chen C, Stepanova A, Paal K, Lee J, Palkovits M, Hudson G &amp; Chinopoulos C (2024) Cell-specific expression of key mitochondrial enzymes limits OXPHOS in astrocytes of the adult human neocortex and hippocampal formation, <em>Commun Biol<\/em> 7: 1045. IF: 5.1<\/li>\n<li style=\"text-align: justify\">D\u00f3ra F, Hajdu T, Renner \u00c9, Pa\u00e1l K, Alp\u00e1r A, Palkovits M, Chinopoulos C &amp; Dobolyi A (2024) Reverse phase protein array-based investigation of mitochondrial genes reveals alteration of glutaminolysis in the parahippocampal cortex of people who died by suicide, <em>Transl Psychiatry<\/em> 14: 479. IF: 6.2<\/li>\n<\/ol>\n<p style=\"text-align: justify\"><strong>Partners within the NAP project<\/strong><\/p>\n<ul>\n<li>Department\u00a0of Anatomy, Histology and Embryology, Semmelweis University (Al\u00e1n Alp\u00e1r)<\/li>\n<li>Institute of Physiology, University of P\u00e9cs Medical School (Istv\u00e1n \u00c1brah\u00e1m\u2020)<\/li>\n<li>Department of Medical Biochemistry, Semmelweis University (Christos Chinopoulos)<\/li>\n<li>Department of Physiology and Neurobiology, E\u00f6tv\u00f6s Lor\u00e1nd University (\u00c1rp\u00e1d\u00a0Dobolyi)<\/li>\n<li>Department of Pharmacology and Pharmacotherapy, University of P\u00e9cs Medical School (Zsuzsanna Helyes)<\/li>\n<li>Institute of Genomic Medicine and Rare Disorders, Semmelweis University (M\u00e1ria Judit Moln\u00e1r)<\/li>\n<li>Department of Physiology, Anatomy and Neuroscience,\u00a0University of Szeged (G\u00e1bor Tam\u00e1s)<\/li>\n<li>\n<div>Neurodegenerative Disease Drug Discovery Group, Research Center for Natural Sciences (Gergely T\u00f3th)<\/div>\n<\/li>\n<\/ul>\n<p><strong>Number of samples we sent to NAP partners:<\/strong><\/p>\n<ul>\n<li style=\"list-style-type: none\">\n<ul style=\"list-style-type: disc\">\n<li>2014: 133<\/li>\n<li>2015:\u00a027<\/li>\n<li>2016: 609<\/li>\n<li>2017: 617<\/li>\n<li>2018: 171<\/li>\n<li>2019: 3<\/li>\n<li>2020: 130<\/li>\n<li>2021: 134<\/li>\n<li>2023: 26<\/li>\n<li>2024: 12<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<blockquote class=\"wp-embedded-content\" data-secret=\"DmtgkCyGCS\"><p><a href=\"https:\/\/semmelweis.hu\/hirek\/2016\/12\/29\/hatvanezer-mintat-tarolnak-a-vilagszinten-is-egyedulallo-human-agyszovet-bank-es-laboratoriumban\/\">Hatvanezer mint\u00e1t t\u00e1rolnak a vil\u00e1gszinten is egyed\u00fcl\u00e1ll\u00f3 Hum\u00e1n Agysz\u00f6vet Bank \u00e9s Laborat\u00f3riumban<\/a><\/p><\/blockquote>\n<p><iframe loading=\"lazy\" class=\"wp-embedded-content\" sandbox=\"allow-scripts\" security=\"restricted\" style=\"position: absolute; visibility: hidden;\" title=\"&#8220;Hatvanezer mint\u00e1t t\u00e1rolnak a vil\u00e1gszinten is egyed\u00fcl\u00e1ll\u00f3 Hum\u00e1n Agysz\u00f6vet Bank \u00e9s Laborat\u00f3riumban&#8221; &#8212; Semmelweis H\u00edrek\" src=\"https:\/\/semmelweis.hu\/hirek\/2016\/12\/29\/hatvanezer-mintat-tarolnak-a-vilagszinten-is-egyedulallo-human-agyszovet-bank-es-laboratoriumban\/embed\/#?secret=kI7t5KEjM9#?secret=DmtgkCyGCS\" data-secret=\"DmtgkCyGCS\" width=\"600\" height=\"338\" frameborder=\"0\" marginwidth=\"0\" marginheight=\"0\" scrolling=\"no\"><\/iframe><\/p>\n<p>&nbsp;<\/p>\n<p><strong><a href=\"http:\/\/nava.hu\/id\/3116652\/#\">Minden tud\u00e1s c. t\u00e9v\u00e9m\u0171sor (2017. m\u00e1rcius 3-i ad\u00e1sa, M1 csatorna)<\/a><\/strong><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Participation of the HBTB in the NAP project <a href=\"https:\/\/semmelweis.hu\/hbtb\/files\/2015\/05\/NAP.jpg\"><\/a> Hungary has launched a National Brain Research Program (Nemzeti Agykutat\u00e1si Program = NAP) with a government subsidy to explore the most frequent diseases of the brain, including depression, migraine, cerebral metastases, Alzheimer&#8217;s and Parkinson&#8217;s disease. Microdissection Researh Group within the HBTB: SE-NAP &#8211; Human Brain Tissue Bank &hellip;<\/p>\n","protected":false},"author":343,"featured_media":0,"parent":0,"menu_order":7,"comment_status":"closed","ping_status":"closed","template":"template-fullwidth.php","meta":{"_acf_changed":false,"footnotes":""},"categories":[],"tags":[],"class_list":["post-48688","page","type-page","status-publish","hentry"],"acf":[],"_links":{"self":[{"href":"https:\/\/semmelweis.hu\/hbtb\/wp-json\/wp\/v2\/pages\/48688","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/semmelweis.hu\/hbtb\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/semmelweis.hu\/hbtb\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/semmelweis.hu\/hbtb\/wp-json\/wp\/v2\/users\/343"}],"replies":[{"embeddable":true,"href":"https:\/\/semmelweis.hu\/hbtb\/wp-json\/wp\/v2\/comments?post=48688"}],"version-history":[{"count":11,"href":"https:\/\/semmelweis.hu\/hbtb\/wp-json\/wp\/v2\/pages\/48688\/revisions"}],"predecessor-version":[{"id":49277,"href":"https:\/\/semmelweis.hu\/hbtb\/wp-json\/wp\/v2\/pages\/48688\/revisions\/49277"}],"wp:attachment":[{"href":"https:\/\/semmelweis.hu\/hbtb\/wp-json\/wp\/v2\/media?parent=48688"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/semmelweis.hu\/hbtb\/wp-json\/wp\/v2\/categories?post=48688"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/semmelweis.hu\/hbtb\/wp-json\/wp\/v2\/tags?post=48688"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}