{"id":1881,"date":"2023-11-27T13:08:59","date_gmt":"2023-11-27T12:08:59","guid":{"rendered":"https:\/\/semmelweis.hu\/gyogyszereszi-kemia\/?page_id=1881"},"modified":"2026-03-19T13:27:53","modified_gmt":"2026-03-19T12:27:53","slug":"elvalasztastechnikai-kutatocsoport","status":"publish","type":"page","link":"https:\/\/semmelweis.hu\/gyogyszereszi-kemia\/kutatas-2\/elvalasztastechnikai-kutatocsoport\/","title":{"rendered":"Elv\u00e1laszt\u00e1stechnikai Kutat\u00f3csoport"},"content":{"rendered":"<p><img decoding=\"async\" src=\"https:\/\/semmelweis.hu\/gyogyszereszi-kemia\/files\/2024\/01\/elvalasztastech_2025-scaled.jpg\" alt=\"\" \/><\/p>\n<h3><span style=\"font-size: 18pt\"><strong>Kutat\u00e1si ter\u00fcletek:<\/strong><\/span><\/h3>\n<ul style=\"list-style-type: square\">\n<li><span style=\"font-size: 14pt\">Kir\u00e1lis m\u00f3dszerfejleszt\u00e9s CE-vel \u00e9s HPLC-vel nagysz\u00e1m\u00fa kir\u00e1lis szelektor felhaszn\u00e1l\u00e1s\u00e1val (poliszacharid, ciklodextrin, feh\u00e9rje, makrociklikus antibiotikum)<\/span><\/li>\n<li><span style=\"font-size: 14pt\">Kir\u00e1lis felismer\u0151k\u00e9pess\u00e9g tanulm\u00e1nyoz\u00e1sa spektroszk\u00f3pi\u00e1s m\u00f3dszerekkel es molekula modellez\u00e9ssel<\/span><\/li>\n<li><span style=\"font-size: 14pt\">Ciklodextrin-alap\u00fa kir\u00e1lis szelektorok fejleszt\u00e9se<\/span><\/li>\n<li><span style=\"font-size: 14pt\">A kir\u00e1lis felimer\u0151k\u00e9pess\u00e9g el\u0151rejelzese g\u00e9pi tanul\u00e1ssal<\/span><\/li>\n<li><span style=\"font-size: 14pt\">Feh\u00e9rje k\u00f6t\u0151des jellemz\u00e9se kromatogr\u00e1fi\u00e1s \u00e9s spektroszk\u00f3pi\u00e1s m\u00f3dszerekkel<\/span><\/li>\n<li><span style=\"font-size: 14pt\">Kir\u00e1lis HPLC-MS m\u00f3dszerek fejleszt\u00e9se<\/span><\/li>\n<\/ul>\n<h3><span style=\"font-size: 18pt\"><strong>TDK\/szakdolgozat t\u00e9m\u00e1k:<\/strong><\/span><\/h3>\n<table style=\"width: 803px\">\n<tbody>\n<tr>\n<td style=\"width: 515px\">\n<p><strong>T\u00c9MA<\/strong><\/p>\n<\/td>\n<td style=\"width: 288px\">\n<p><strong>T\u00c9MAVEZET\u0150(K)<\/strong><\/p>\n<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 515px\">Feh\u00e9rje \u00e1ll\u00f3f\u00e1zisok korszer\u0171 haszn\u00e1lat\u00e1nak lehet\u0151s\u00e9gei<\/td>\n<td style=\"width: 288px\">Dr. Dombi Gergely, Dr. T\u00f3th Gerg\u0151<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 515px\">Kir\u00e1lis anyagok vizsg\u00e1lata gy\u00f3gyszerk\u00f6nyvekben (irodalmaz\u00e1s)<\/td>\n<td style=\"width: 288px\">Dr. Dombi Gergely, Dr. T\u00f3th Gerg\u0151<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 515px\">Enantiomerelv\u00e1laszt\u00e1s el\u0151rejelz\u00e9se g\u00e9pi tanul\u00e1ssal<\/td>\n<td style=\"width: 288px\">Dr. T\u00f3th Gerg\u0151<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 515px\">Kir\u00e1lis elv\u00e1laszt\u00e1sok ciklodextrin- \u00e9s poliszacharid \u00e1ll\u00f3f\u00e1zisokon<\/td>\n<td style=\"width: 288px\">Dr. T\u00f3th Gerg\u0151<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h3><span style=\"font-size: 18pt\"><strong>PhD t\u00e9m\u00e1k:<\/strong><\/span><\/h3>\n<table style=\"border-collapse: collapse;width: 100%\">\n<tbody>\n<tr>\n<td style=\"width: 100%\">\n<ul style=\"list-style-type: square\">\n<li><span style=\"font-size: 14pt\"><a href=\"https:\/\/doktori.hu\/index.php?menuid=195&amp;lang=HU&amp;tk_ID=239754\">Enantioszelekt\u00edv analitikai m\u00f3dszerek fejleszt\u00e9se<\/a><\/span><\/li>\n<\/ul>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h3><span style=\"font-size: 18pt\"><strong>Friss k\u00f6zlem\u00e9nyek:<\/strong><\/span><\/h3>\n<ol>\n<li style=\"list-style-type: none\">\n<ol>\n<li>\n<p>Ferencz, E.\u00a0;\u00a0Szab\u00f3, Z.-I.\u00a0;\u00a0Z\u00f6ldhegyi, A.\u00a0;\u00a0<strong>Dombi, G<\/strong>.\u00a0;\u00a0<strong>Moln\u00e1r, G.<\/strong>\u00a0;\u00a0<strong>Dob\u00f3, M<\/strong>.\u00a0;\u00a0Varga, E.\u00a0;\u00a0Moln\u00e1r, I.\u00a0;\u00a0<strong>T\u00f3th, G.:<\/strong> Possibilities and limitations of computer assisted chiral HPLC method development for ozanimod on polysaccharide based chiral stationary phases,\u00a0 SCIENTIFIC REPORTS\u00a014\u00a0:\u00a01\u00a0Paper: 26757 , 12 p.\u00a0(<strong>2024<\/strong>)<br \/>\nDOI: <a href=\"https:\/\/doi.org\/10.1038\/s41598-024-78415-1\">10.1038\/s41598-024-78415-1<\/a><\/p>\n<\/li>\n<li>\n<p><strong>Dombi, G.<\/strong>\u00a0;\u00a0Tyukodi, L.\u00a0;\u00a0<strong>Dob\u00f3, M.<\/strong>\u00a0;\u00a0<strong>Moln\u00e1r, G<\/strong>.\u00a0;\u00a0Rozmer, Zs.\u00a0;\u00a0Szab\u00f3, Z.-I.\u00a0;\u00a0Fiser, B.\u00a0;\u00a0<strong>T\u00f3th, G.<\/strong>: Enantioselective Binding of Proton Pump Inhibitors to Alpha1-Acid Glycoprotein and Human Serum Albumin\u2014A Chromatographic, Spectroscopic, and In Silico Study, INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES\u00a025\u00a0:\u00a019\u00a0Paper: 10575 , 20 p.\u00a0(<strong>2024<\/strong>)<br \/>\nDOI: <a href=\"https:\/\/doi.org\/10.3390\/ijms251910575\">10.3390\/ijms251910575<\/a><\/p>\n<\/li>\n<li>\n<p><strong>Dob\u00f3, M.<\/strong>\u00a0;\u00a0<strong>Dombi, G.<\/strong>\u00a0;\u00a0K\u00f6teles, I.\u00a0;\u00a0Fiser, B.\u00a0;\u00a0Kis, Cs.\u00a0;\u00a0Szab\u00f3, Z.-I.\u00a0;\u00a0<strong>T\u00f3th, G.<\/strong>: Simultaneous Determination of Enantiomeric Purity and Organic Impurities of Dexketoprofen Using Reversed-Phase Liquid Chromatography\u2014Enhancing Enantioselectivity through Hysteretic Behavior and Temperature-Dependent Enantiomer Elution Order Reversal on Polysaccharide Chiral Stationary Phases, INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES\u00a025\u00a0:\u00a05\u00a0Paper: 2697 , 15 p.\u00a0(<strong>2024<\/strong>)<br \/>\nDOI: <a href=\"https:\/\/doi.org\/10.3390\/ijms25052697\">10.3390\/ijms25052697<\/a><\/p>\n<\/li>\n<li>\n<p><strong>Dob\u00f3, M<\/strong>.\u00a0;\u00a0\u00c1d\u00e1m, M.\u00a0;\u00a0Fiser, B.\u00a0;\u00a0Papp, L.A.\u00a0;\u00a0<strong>Dombi, G<\/strong>.\u00a0;\u00a0Sekkoum, K.\u00a0;\u00a0Szab\u00f3, Z.-I.\u00a0<strong>;\u00a0T\u00f3th, G<\/strong>.: Enantioseparation and molecular docking study of selected chiral pharmaceuticals on a commercialized phenylcarbamate-\u03b2-cyclodextrin column using polar organic mode, SCIENTIFIC REPORTS 13 : 1 Paper: 14778 , 14 p. (<strong>2023<\/strong>)<br \/>\nDOI: <a href=\"http:\/\/doi.org\/10.1038\/s41598-023-41941-5\">10.1038\/s41598-023-41941-5<\/a><\/p>\n<\/li>\n<li>\n<p><strong>Dombi, G<\/strong>.\u00a0;\u00a0<strong>Horv\u00e1th, P.<\/strong>\u00a0;\u00a0Fiser, B.\u00a0;\u00a0<strong>Mirzahosseini, A.<\/strong>\u00a0;\u00a0<strong>Dob\u00f3, M<\/strong>.\u00a0;\u00a0Szab\u00f3, Zolt\u00e1n-Istv\u00e1n\u00a0;\u00a0<strong>T\u00f3th, G.<\/strong>: <em>Enantioselective Human Serum Albumin Binding of Apremilast: Liquid Chromatographic, Fluorescence and Molecular Docking Study<\/em>, INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES\u00a024\u00a0:\u00a03\u00a0Paper: 2168 , 15 p.\u00a0(<strong>2023<\/strong>)<br \/>\nDOI: <a href=\"https:\/\/doi.org\/10.3390\/ijms24032168\">10.3390\/ijms24032168<\/a><\/p>\n<\/li>\n<\/ol>\n<\/li>\n<\/ol>\n<p><strong>A kutat\u00f3munka a Nemzeti Kutat\u00e1si, Fejleszt\u00e9si \u00e9s Innov\u00e1ci\u00f3s Hivatal OTKA FK-146930 sz\u00e1m\u00fa projekt keret\u00e9ben \u00e9s t\u00e1mogat\u00e1s\u00e1val val\u00f3sul meg.<\/strong><\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter\" src=\"https:\/\/semmelweis.hu\/gyogyszereszi-kemia\/files\/2025\/01\/Kep1.jpg\" alt=\"\" width=\"615\" height=\"261\" \/><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Kutat\u00e1si ter\u00fcletek: Kir\u00e1lis m\u00f3dszerfejleszt\u00e9s CE-vel \u00e9s HPLC-vel nagysz\u00e1m\u00fa kir\u00e1lis szelektor felhaszn\u00e1l\u00e1s\u00e1val (poliszacharid, ciklodextrin, feh\u00e9rje, makrociklikus antibiotikum) Kir\u00e1lis felismer\u0151k\u00e9pess\u00e9g tanulm\u00e1nyoz\u00e1sa spektroszk\u00f3pi\u00e1s m\u00f3dszerekkel es molekula modellez\u00e9ssel Ciklodextrin-alap\u00fa kir\u00e1lis szelektorok fejleszt\u00e9se A kir\u00e1lis felimer\u0151k\u00e9pess\u00e9g el\u0151rejelzese g\u00e9pi tanul\u00e1ssal Feh\u00e9rje k\u00f6t\u0151des jellemz\u00e9se kromatogr\u00e1fi\u00e1s \u00e9s spektroszk\u00f3pi\u00e1s m\u00f3dszerekkel Kir\u00e1lis HPLC-MS m\u00f3dszerek fejleszt\u00e9se TDK\/szakdolgozat t\u00e9m\u00e1k: T\u00c9MA T\u00c9MAVEZET\u0150(K) Feh\u00e9rje \u00e1ll\u00f3f\u00e1zisok korszer\u0171 haszn\u00e1lat\u00e1nak lehet\u0151s\u00e9gei Dr. &hellip;<\/p>\n","protected":false},"author":102300,"featured_media":0,"parent":1915,"menu_order":1,"comment_status":"closed","ping_status":"closed","template":"template-fullwidth.php","meta":{"_acf_changed":false,"footnotes":""},"categories":[23],"tags":[],"class_list":["post-1881","page","type-page","status-publish","hentry","category-kutatas"],"acf":[],"_links":{"self":[{"href":"https:\/\/semmelweis.hu\/gyogyszereszi-kemia\/wp-json\/wp\/v2\/pages\/1881","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/semmelweis.hu\/gyogyszereszi-kemia\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/semmelweis.hu\/gyogyszereszi-kemia\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/semmelweis.hu\/gyogyszereszi-kemia\/wp-json\/wp\/v2\/users\/102300"}],"replies":[{"embeddable":true,"href":"https:\/\/semmelweis.hu\/gyogyszereszi-kemia\/wp-json\/wp\/v2\/comments?post=1881"}],"version-history":[{"count":10,"href":"https:\/\/semmelweis.hu\/gyogyszereszi-kemia\/wp-json\/wp\/v2\/pages\/1881\/revisions"}],"predecessor-version":[{"id":3032,"href":"https:\/\/semmelweis.hu\/gyogyszereszi-kemia\/wp-json\/wp\/v2\/pages\/1881\/revisions\/3032"}],"up":[{"embeddable":true,"href":"https:\/\/semmelweis.hu\/gyogyszereszi-kemia\/wp-json\/wp\/v2\/pages\/1915"}],"wp:attachment":[{"href":"https:\/\/semmelweis.hu\/gyogyszereszi-kemia\/wp-json\/wp\/v2\/media?parent=1881"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/semmelweis.hu\/gyogyszereszi-kemia\/wp-json\/wp\/v2\/categories?post=1881"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/semmelweis.hu\/gyogyszereszi-kemia\/wp-json\/wp\/v2\/tags?post=1881"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}