Department of Pharmaceutical Chemistry
Address: H-1092 Budapest, Hőgyes Endre u. 9.
Phone/Fax: +36 1 217 0891
Director: Professor Dr. György Tibor Balogh
Profile
The scope of teaching involves two compulsory and one elective subjects at the undergraduate level and various courses at postgraduate and Ph.D. levels. Fundamental and applied drug research topics are both represented, often within the context of industrial and international collaborations, including pharmacopoeial analysis.
History
The Department was established in 1949. Its former directors were Dr. Antal Végh (1949-1974), Dr. György Szász (1974-1994), Dr. Béla Noszál (1994-2012) and Dr. Péter Horváth (2012-2023)
Education
The Department’s undregraduate courses are:
- Pharmaceutical Chemistry and Analysis
- Instrumental Analysis
- Spectrocopic Methods for Structure Elucidation
Research
Various fields of pharmaceutical and medicinal chemistry are investigated:
- Determination of biological activity-related physico-chemical parameters, such as macroscopic and microscopic protonation constants, lipophilicity of drug- and drug candidate molecules; solubility
- Structural characterisation of drugs and drug-receptor interactions by NMR, UV, CD, IR, molecular modelling, and QSAR methods;
- Development and application of separation techniques: HPLC, HPCE, GC, TLC;
- Synthesis of potential lead compounds by traditional methods, combinatorial chemistry and parallel synthesis;
- Elaboration of techniques to develop molecules to be used in cancer therapy and CNS diseases.
