{"id":171,"date":"2026-07-29T10:10:09","date_gmt":"2026-07-29T08:10:09","guid":{"rendered":"https:\/\/semmelweis.hu\/gsi\/?page_id=171"},"modified":"2026-08-28T11:19:04","modified_gmt":"2026-08-28T09:19:04","slug":"molekularis-onkobiologia","status":"publish","type":"page","link":"https:\/\/semmelweis.hu\/gsi\/kutatas\/molekularis-onkobiologia\/","title":{"rendered":"Molekul\u00e1ris Onkobiol\u00f3giai Kutat\u00f3csoport"},"content":{"rendered":"

Vezet\u0151: Prof. Wiener Zolt\u00e1n<\/h2>\n

\"\"<\/p>\n

\n

Bemutatkoz\u00e1s<\/h2>\n
\n\n

Bemutatkoz\u00e1s<\/h2>\n

\"\"Colorectal cancer<\/strong>\u00a0(CRC)<\/strong>\u00a0is\u00a0one of the leading causes of cancer related death in Hungary and in the Western countries. Despite the progress in understanding colorectal tumorigenesis, this disease still represents an outstanding health problem. Recent reports have proved that not only the tumor cells, but also the stromal cells critically contribute to the tumor progression and patient survival.
\n<\/strong><\/p>\n

The 5-year patient survival is extremely low in\u00a0pancreatic and lung cancers<\/strong>, partially due to the late diagnosis and the lack of early signs of these diseases.<\/p>\n

Our mission <\/strong>is to identify novel communication mechanisms between tumor cells and the stroma that can form the basis of future therapeutic interventions in CRC, PDAC and lung cancer. Furthermore,\u00a0 we aim at identifying novel early biomarkers for lung and pancreatic cancers. One of our interests is the function of the extracellular vesicles that represent a novel form of cell-to-cell communication.<\/p>\n

\"\"We use a large array of state-of-the-art methods to answer our biological questions, such as the patient-derived organoid technology and the genome editing CRISPR-Cas9 method<\/strong>.\u00a0Our research group is financed by grants from the Semmelweis University and by the National Research, Development and Innovation Office (Hungary).<\/p>\n

 <\/p>\n

 <\/p>\n

 <\/p>\n\n<\/div>

Tagok<\/h2>\n
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Tagok<\/h2>\n\r\n

Ha hib\u00e1s, vagy hi\u00e1nyz\u00f3 adatot tal\u00e1l, k\u00e9rj\u00fck jelezze szervezeti egys\u00e9g\u00fcnk titk\u00e1rs\u00e1g\u00e1n.<\/span><\/p>\r\n

A telefonk\u00f6nyvben tal\u00e1lhat\u00f3 adatok nem haszn\u00e1lhat\u00f3k fel az 1995. \u00e9vi CXIX. t\u00f6rv\u00e9ny szerinti kutat\u00e1s \u00e9s k\u00f6zvetlen \u00fczletszerz\u00e9s c\u00e9lj\u00e1ra.<\/em><\/p>\r\n

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\r\n Prof. Wiener Zolt\u00e1n<\/a>\r\n
egyetemi tan\u00e1r, az MTA doktora<\/span><\/div>\r\n
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\r\n Bord\u00e1s Fanni<\/a>\r\n
kutat\u00e1si asszisztens<\/span><\/div>\r\n
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\u00a0<\/h5>\n
TDK hallgat\u00f3k<\/h5>\n