{"id":43579,"date":"2025-01-07T06:00:39","date_gmt":"2025-01-07T05:00:39","guid":{"rendered":"https:\/\/semmelweis.hu\/english\/?p=43579"},"modified":"2025-02-01T20:42:50","modified_gmt":"2025-02-01T19:42:50","slug":"once-again-two-semmelweis-academics-are-among-the-worlds-highly-cited-researchers","status":"publish","type":"post","link":"https:\/\/semmelweis.hu\/english\/2025\/01\/once-again-two-semmelweis-academics-are-among-the-worlds-highly-cited-researchers\/","title":{"rendered":"Once again, two Semmelweis academics are among the world&#8217;s Highly Cited Researchers"},"content":{"rendered":"<div class=\"lead\">Dr. P\u00e9ter Ferdinandy, Vice-Rector for Science and Innovations, Head of the Department of Pharmacology and Pharmacotherapy, and Dr. Bal\u00e1zs Gy\u0151rffy, Head of the Department of Bioinformatics, have once again been included in the recent list of the world&#8217;s highly cited researchers.<\/div>\n<p><a href=\"https:\/\/semmelweis.hu\/english\/files\/2025\/01\/RS150545_C19A1890-scr.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"alignleft size-medium wp-image-43582\" src=\"https:\/\/semmelweis.hu\/english\/files\/2025\/01\/RS150545_C19A1890-scr-283x400.jpg\" alt=\"\" width=\"283\" height=\"400\" srcset=\"https:\/\/semmelweis.hu\/english\/files\/2025\/01\/RS150545_C19A1890-scr-283x400.jpg 283w, https:\/\/semmelweis.hu\/english\/files\/2025\/01\/RS150545_C19A1890-scr.jpg 637w\" sizes=\"auto, (max-width: 283px) 100vw, 283px\" \/><\/a>The <a href=\"https:\/\/clarivate.com\/highly-cited-researchers\/?action=clv_hcr_members_filter&amp;clv-paged=1&amp;clv-category=&amp;clv-institution=Semmelweis%20University&amp;clv-region=&amp;clv-name=\" target=\"_blank\" rel=\"noopener\">Highly Cited Researchers 2024 list<\/a> examines citations across 21 fields of research, based on data derived from the Web of Science. Highly Cited Papers are in the top 1 percent of their discipline by citations. Researchers must author multiple Highly Cited Papers, the number of which varies by field of science. The 2024 list contains 6,886 names, representing less than one-thousandth of all researchers.<\/p>\n<p>Among Dr. P\u00e9ter Ferdinandy&#8217;s recent research, the most cited publications are mainly those focusing on cardiovascular research, with particular emphasis on mechanisms of myocardial ischemia\/reperfusion injury and cardioprotective strategies. (Cardioprotection includes all mechanisms, medicinal or instrumental interventions that contribute to the preservation of heart health by reducing or preventing the extent of myocardial damage.) Most of his publications are the result of international or corporate collaborations and have appeared in high-impact journals such as <em>Cardiovascular Research<\/em> and <em>Pharmacological Reviews<\/em>.<\/p>\n<p><a href=\"https:\/\/semmelweis.hu\/english\/files\/2025\/01\/RS146079_TZ_20220303_0317-scr-1.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"alignright size-medium wp-image-43583\" src=\"https:\/\/semmelweis.hu\/english\/files\/2025\/01\/RS146079_TZ_20220303_0317-scr-1-400x267.jpg\" alt=\"\" width=\"400\" height=\"267\" srcset=\"https:\/\/semmelweis.hu\/english\/files\/2025\/01\/RS146079_TZ_20220303_0317-scr-1-400x267.jpg 400w, https:\/\/semmelweis.hu\/english\/files\/2025\/01\/RS146079_TZ_20220303_0317-scr-1-900x600.jpg 900w, https:\/\/semmelweis.hu\/english\/files\/2025\/01\/RS146079_TZ_20220303_0317-scr-1-753x502.jpg 753w, https:\/\/semmelweis.hu\/english\/files\/2025\/01\/RS146079_TZ_20220303_0317-scr-1-203x135.jpg 203w, https:\/\/semmelweis.hu\/english\/files\/2025\/01\/RS146079_TZ_20220303_0317-scr-1.jpg 1200w\" sizes=\"auto, (max-width: 400px) 100vw, 400px\" \/><\/a>Dr. Bal\u00e1zs Gy\u0151rffy&#8217;s most cited papers are from the fields of oncology and bioinformatics. One of the oncology research projects conducted by his team revolves around the &#8220;cancer hallmarks&#8221; theory, which reveals the common biological and metabolic characteristics of different types of tumors. This framework provides key insights into cancer prevention, diagnosis, and the development of new therapies. The CancerHallmarks project has merged 6,763 genes from available sources to create a consensual list of genes associated with cancer. The resulting platform (<a href=\"https:\/\/cancerhallmarks.com\/\" target=\"_blank\" rel=\"noopener\">www.cancerhallmarks.com<\/a>) links genes to their biological functions.<\/p>\n<p>Another study of Dr. Bal\u00e1zs Gy\u0151rffy&#8217;s team focuses on a deeper understanding of epigenetic regulation in colorectal cancer. In the framework of this, a comprehensive database has been created, which integrates DNA methylation patterns from normal tissues, adenomas, and adenocarcinomas. The analysis has identified several key, differentially methylated regions in genes such as C1orf70, ITGA4, and NPY, which have high diagnostic and therapeutic potential. The results have been made available on an interactive, online platform (<a href=\"https:\/\/www.epigenplot.com\/\" target=\"_blank\" rel=\"noopener\">www.epigenplot.com<\/a>) that supports researchers in further exploring methylation-based biomarkers and therapeutic targets.<\/p>\n<p>Anita Szepesi <br \/>\nTranslation: Judit Szabados-D\u0151tsch<br \/>\nPhotos by Attila Kov\u00e1cs \u2013 Semmelweis University, Zolt\u00e1n Tuba \u2013 K\u00e9pszerkeszt\u0151s\u00e9g<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Dr. P\u00e9ter Ferdinandy and Dr. Bal\u00e1zs Gy\u0151rffy have reentered the 2024 list.<\/p>\n","protected":false},"author":102255,"featured_media":43580,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[13,286],"tags":[29],"class_list":["post-43579","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-science","category-x-nyitolap","tag-research"],"acf":[],"_links":{"self":[{"href":"https:\/\/semmelweis.hu\/english\/wp-json\/wp\/v2\/posts\/43579","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/semmelweis.hu\/english\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/semmelweis.hu\/english\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/semmelweis.hu\/english\/wp-json\/wp\/v2\/users\/102255"}],"replies":[{"embeddable":true,"href":"https:\/\/semmelweis.hu\/english\/wp-json\/wp\/v2\/comments?post=43579"}],"version-history":[{"count":3,"href":"https:\/\/semmelweis.hu\/english\/wp-json\/wp\/v2\/posts\/43579\/revisions"}],"predecessor-version":[{"id":43587,"href":"https:\/\/semmelweis.hu\/english\/wp-json\/wp\/v2\/posts\/43579\/revisions\/43587"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/semmelweis.hu\/english\/wp-json\/wp\/v2\/media\/43580"}],"wp:attachment":[{"href":"https:\/\/semmelweis.hu\/english\/wp-json\/wp\/v2\/media?parent=43579"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/semmelweis.hu\/english\/wp-json\/wp\/v2\/categories?post=43579"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/semmelweis.hu\/english\/wp-json\/wp\/v2\/tags?post=43579"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}