{"id":32037,"date":"2022-06-15T10:20:46","date_gmt":"2022-06-15T08:20:46","guid":{"rendered":"https:\/\/semmelweis.hu\/english\/?p=32037"},"modified":"2022-06-20T17:20:08","modified_gmt":"2022-06-20T15:20:08","slug":"study-looking-at-differences-among-migraine-subgroups-may-help-understand-the-diurnal-variation-in-migraine-attacks","status":"publish","type":"post","link":"https:\/\/semmelweis.hu\/english\/2022\/06\/study-looking-at-differences-among-migraine-subgroups-may-help-understand-the-diurnal-variation-in-migraine-attacks\/","title":{"rendered":"Study looking at differences among migraine subgroups may help understand the diurnal variation in migraine attacks"},"content":{"rendered":"<div class=\"lead\">To identify the causes of migraine more precisely, the researchers of Semmelweis University in Budapest have looked at how migraineurs process emotions based on the circadian onset of the attacks. Since this is the first study to investigate such a link, further research is needed but the results may bring targeted treatment a step closer to patients.\u00a0<\/div>\n<p>The researchers first categorized patients based on when the attack began. One third of the people asked reported morning attacks, 40% experienced migraine in the afternoon\/evening, while a third couldn\u2019t specify a certain time of the day. Then they looked at how people in each group processed emotions by showing them images of faces with different emotional expressions.<\/p>\n<p><a href=\"https:\/\/semmelweis.hu\/english\/files\/2022\/06\/RS151556_3P1A3919-scr.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"alignleft wp-image-32086 size-medium\" src=\"https:\/\/semmelweis.hu\/english\/files\/2022\/06\/RS151556_3P1A3919-scr-400x267.jpg\" alt=\"\" width=\"400\" height=\"267\" srcset=\"https:\/\/semmelweis.hu\/english\/files\/2022\/06\/RS151556_3P1A3919-scr-400x267.jpg 400w, https:\/\/semmelweis.hu\/english\/files\/2022\/06\/RS151556_3P1A3919-scr-900x600.jpg 900w, https:\/\/semmelweis.hu\/english\/files\/2022\/06\/RS151556_3P1A3919-scr-753x502.jpg 753w, https:\/\/semmelweis.hu\/english\/files\/2022\/06\/RS151556_3P1A3919-scr-203x135.jpg 203w, https:\/\/semmelweis.hu\/english\/files\/2022\/06\/RS151556_3P1A3919-scr.jpg 1200w\" sizes=\"auto, (max-width: 400px) 100vw, 400px\" \/><\/a>\u201cOur findings from previous research indicate that migraineurs tend to process emotions somewhat differently than healthy people. This time we focused on any potential difference among migraine subgroups\u201d <span style=\"font-size: 1rem\">\u2013 said Gabriella Juh\u00e1sz, associate professor at the Department of Pharmacodynamics, Faculty of Pharmacy, Semmelweis University.<\/span><\/p>\n<div class=\"fontos_div\">\n<p>In the two studies conducted, they found differences among groups in their response to images showing fearful faces at parts of the brain responsible for processing pain and sensory related information.<\/p>\n<\/div>\n<p>However, which group showed differences, varied. In the first study, the evening group showed more enhanced activity compared to the morning group. In the second one, researchers recorded increased activity in the morning group compared to the mixed onset group.<\/p>\n<p>Migraine is caused by various (environmental, hormonal, genetic) factors including ones related to our biological rhythm. The quality and quantity of sleep as well as hormonal changes prior to waking up may trigger morning attacks, while external factors such as stress at work or school can be a reason for migraines in the evening.<\/p>\n<p>Therefore, identifying what causes an attack can be the pathway to more targeted treatment.<\/p>\n<blockquote>\n<p>Today, only a fraction of people responds (well) to treatment. If we can categorize patients into subgroups and pinpoint the related causes such as time of day and alterations in biological processes, e.g in sleep patterns, we may be able to treat them more effectively<\/p>\n<\/blockquote>\n<p><span style=\"font-size: 1rem\">\u2013 <\/span>Juh\u00e1sz says.<\/p>\n<p>For successful treatment, time is also key. Patients who can recognize warning signs early on may be able to head off migraine or keep it from getting worse. Slow-release drugs are available for patients with migraine in the morning but they have to be taken at bedtime. In the case of morning migraines, investigating and treating sleeping problems may also help. Those suffering from pain in the afternoon should try and reduce stress or apply techniques to manage it, the expert notes.<\/p>\n<p>Migraine is a major global health issue that affects over 10% of the population. It is the\u00a0second leading cause of years lived with disability worldwide and the leading one for young, productive women.<\/p>\n<p>You can find the full study <a href=\"https:\/\/www.frontiersin.org\/articles\/10.3389\/fnhum.2022.842426\/full\">here<\/a>.<\/p>\n<p>Photo: B\u00e1lint Barta <span style=\"font-size: 1rem\">\u2013 Semmelweis University<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Understanding the differences between morning and evening migraineurs may help more effective treatment. <\/p>\n","protected":false},"author":102059,"featured_media":32085,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[13,2,286],"tags":[261],"class_list":["post-32037","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-science","category-news","category-x-nyitolap","tag-press"],"acf":[],"_links":{"self":[{"href":"https:\/\/semmelweis.hu\/english\/wp-json\/wp\/v2\/posts\/32037","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/semmelweis.hu\/english\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/semmelweis.hu\/english\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/semmelweis.hu\/english\/wp-json\/wp\/v2\/users\/102059"}],"replies":[{"embeddable":true,"href":"https:\/\/semmelweis.hu\/english\/wp-json\/wp\/v2\/comments?post=32037"}],"version-history":[{"count":5,"href":"https:\/\/semmelweis.hu\/english\/wp-json\/wp\/v2\/posts\/32037\/revisions"}],"predecessor-version":[{"id":32185,"href":"https:\/\/semmelweis.hu\/english\/wp-json\/wp\/v2\/posts\/32037\/revisions\/32185"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/semmelweis.hu\/english\/wp-json\/wp\/v2\/media\/32085"}],"wp:attachment":[{"href":"https:\/\/semmelweis.hu\/english\/wp-json\/wp\/v2\/media?parent=32037"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/semmelweis.hu\/english\/wp-json\/wp\/v2\/categories?post=32037"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/semmelweis.hu\/english\/wp-json\/wp\/v2\/tags?post=32037"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}