{"id":28652,"date":"2021-11-23T08:37:43","date_gmt":"2021-11-23T07:37:43","guid":{"rendered":"https:\/\/semmelweis.hu\/english\/?p=28652"},"modified":"2021-11-16T10:32:03","modified_gmt":"2021-11-16T09:32:03","slug":"cardiac-resynchronization-therapy-follow-up-study","status":"publish","type":"post","link":"https:\/\/semmelweis.hu\/english\/2021\/11\/cardiac-resynchronization-therapy-follow-up-study\/","title":{"rendered":"Cardiac resynchronization therapy follow-up study"},"content":{"rendered":"<p><strong>Long-term survival following upgrade compared with <em>de novo<\/em> cardiac resynchronization therapy implantation: a single-centre, high-volume experience<\/strong><\/p>\n<p><a href=\"https:\/\/semmelweis.hu\/hirek\/files\/2021\/10\/Figure-753x565.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"alignleft \" src=\"https:\/\/semmelweis.hu\/hirek\/files\/2021\/10\/Figure-753x565.jpg\" width=\"440\" height=\"330\" \/><\/a>Cardiac resynchronization therapy (CRT) is an effective treatment in symptomatic heart failure (HF) patients. The study compared the results of two groups of patients undergoing CRT procedures. \u201c<em>De novo<\/em>\u201d patients received their first implanted devices, while the second group consisted of patients whose previously implanted devices (pacemakers, cardioverter-defibrillators) got updated to a CRT device. Regarding the baseline clinical characteristics, upgrade patients were significantly older, suffered more frequently from other diseases compared to <em>de novo<\/em> patients. Females were less common in the <em>upgrade<\/em> patient group.\u00a0<\/p>\n<p>&#8220;During the median follow-up time of 3.7 years we demonstrated a 41% higher risk of mortality in <em>upgrade<\/em> compared to <em>de novo<\/em> patients. Further analysis has found that the \u201c<em>upgrade<\/em>\u201d intervention is not an independent predictor of mortality. The higher mortality rates in the <em>upgrade<\/em> group may be attributable to the higher comorbidity burden of <em>upgrade<\/em> patients. The rate of peri- and post-procedural complications (i.e. lead dysfunction and pocket infections) was higher among <em>upgrade<\/em> patients than in the <em>de novo<\/em> group,&#8221; \u2013 added Walter Rich\u00e1rd Schwertner, student of the Doctoral School of Theoretical and Translational Medicine.<\/p>\n<div class=\"keretes w-100\">\n<p>Long-term survival following upgrade compared with de novo cardiac resynchronization therapy implantation: a single-centre, high-volume experience<br \/>\nWalter Richard Schwerner (Heart and Vascular Centre, Semmelweis University), Anett Behon (Heart and Vascular Centre, Semmelweis University), Eperke D\u00f3ra Merkely (Heart and Vascular Centre, Semmelweis University), Marton Tokodi (Heart and Vascular Centre, Semmelweis University), Attila Kovacs (Heart and Vascular Centre, Semmelweis University), Endre Zima (Heart and Vascular Centre, Semmelweis University), Istvan Osztheimer (Heart and Vascular Centre, Semmelweis University), Levente Molnar (Heart and Vascular Centre, Semmelweis University), Akos Kiraly (Heart and Vascular Centre, Semmelweis University), Roland Papp (Heart and Vascular Centre, Semmelweis University), Laszlo Geller (Heart and Vascular Centre, Semmelweis University), Luca Kuthi (Heart and Vascular Centre, Semmelweis University), Boglarka Veres (Heart and Vascular Centre, Semmelweis University), Annamaria Kosztin (Heart and Vascular Centre, Semmelweis University), Bela Merkely (Heart and Vascular Centre, Semmelweis University)<br \/>\nEP Europace (2021), Volume 23, Issue 8, Pages 1310\u20131318.<\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>The study compared the results of two groups of patients undergoing cardiac resynchronization therapy<\/p>\n","protected":false},"author":362,"featured_media":28661,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[13],"tags":[121],"class_list":["post-28652","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-science","tag-science"],"acf":[],"_links":{"self":[{"href":"https:\/\/semmelweis.hu\/english\/wp-json\/wp\/v2\/posts\/28652","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/semmelweis.hu\/english\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/semmelweis.hu\/english\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/semmelweis.hu\/english\/wp-json\/wp\/v2\/users\/362"}],"replies":[{"embeddable":true,"href":"https:\/\/semmelweis.hu\/english\/wp-json\/wp\/v2\/comments?post=28652"}],"version-history":[{"count":3,"href":"https:\/\/semmelweis.hu\/english\/wp-json\/wp\/v2\/posts\/28652\/revisions"}],"predecessor-version":[{"id":28662,"href":"https:\/\/semmelweis.hu\/english\/wp-json\/wp\/v2\/posts\/28652\/revisions\/28662"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/semmelweis.hu\/english\/wp-json\/wp\/v2\/media\/28661"}],"wp:attachment":[{"href":"https:\/\/semmelweis.hu\/english\/wp-json\/wp\/v2\/media?parent=28652"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/semmelweis.hu\/english\/wp-json\/wp\/v2\/categories?post=28652"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/semmelweis.hu\/english\/wp-json\/wp\/v2\/tags?post=28652"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}