{"id":133,"date":"2020-09-14T15:03:43","date_gmt":"2020-09-14T13:03:43","guid":{"rendered":"https:\/\/semmelweis.hu\/endokrinologia\/?page_id=133"},"modified":"2026-04-10T21:50:51","modified_gmt":"2026-04-10T19:50:51","slug":"kutatasok-a-tanszeken","status":"publish","type":"page","link":"https:\/\/semmelweis.hu\/endokrinologia\/kutatasok-a-tanszeken\/","title":{"rendered":"Kutat\u00e1s"},"content":{"rendered":"

Az Endokrinol\u00f3giai Tansz\u00e9k Kutat\u00e1si tev\u00e9kenys\u00e9ge az endokrinol\u00f3gia sz\u00e9les ter\u00fclet\u00e9t \u00f6leli fel.<\/strong><\/p>\n

Mell\u00e9kvese daganatok<\/strong><\/p>\n

Prof. Igaz P\u00e9ter kutat\u00e1sainak k\u00f6z\u00e9ppontj\u00e1ban, els\u0151sorban a mell\u00e9kvese-daganatok g\u00e9nexpresszi\u00f3s vizsg\u00e1latait, mikroRNS-ek kutat\u00e1s\u00e1t v\u00e9gzi \u00faj biomarkerek \u00e9s potenci\u00e1lis \u00faj kezel\u00e9si lehet\u0151s\u00e9gek ir\u00e1ny\u00e1ban. A kutat\u00f3csoport az els\u0151k k\u00f6z\u00f6tt \u00edrta le a mell\u00e9kvesek\u00e9reg \u00e9s mell\u00e9kvesevel\u0151 daganatok mikroRNS expresszi\u00f3s mint\u00e1zat\u00e1t \u00e9s mell\u00e9kvesek\u00e9reg carcinom\u00e1ban els\u0151k\u00e9nt v\u00e9gzett funkcion\u00e1lis genomikai metaanal\u00edzist. Az ut\u00f3bbi \u00e9vekben a kutat\u00f3csoport \u00e9rdekl\u0151d\u00e9se a minim\u00e1lisan invaz\u00edv, v\u00e9rb\u0151l kinyerhet\u0151 mikroRNS biomarkerek fel\u00e9 fordult, \u00e9s e t\u00e9m\u00e1ban sz\u00e1mos k\u00f6zlem\u00e9ny\u00fck jelent meg. A kutat\u00f3csoport vizsg\u00e1lta a 9-cisz retinsav alkalmazhat\u00f3s\u00e1g\u00e1t mell\u00e9kvesek\u00e9reg carcinom\u00e1ban t\u00f6bb k\u00eds\u00e9rleti modellben is.<\/p>\n

A kutat\u00f3csoport 2020-ban elnyerte az ENSAT (European Network for the Study of Adrenal Tumors) kutat\u00e1si kiv\u00e1l\u00f3s\u00e1gi centrum<\/a> kit\u00fcntet\u00e9s\u00e9t, amit 2025-ben reakkredit\u00e1ltak..<\/p>\n

V\u00e1logatott publik\u00e1ci\u00f3k e t\u00e9m\u00e1ban:<\/strong><\/p>\n

    \n
  1. mikroRNS-ek \u00e9s extracellul\u00e1ris vezikul\u00e1k vizsg\u00e1lata mell\u00e9kvesek\u00e9reg daganatokban<\/a><\/li>\n
  2. sz\u00f6veti mikroRNS-ek pheochromocytom\u00e1ban<\/a><\/li>\n
  3. sz\u00f6veti mikroRNS-ek mell\u00e9kvesk\u00e9reg daganatokban<\/a><\/li>\n
  4. bioinformatikai metaanal\u00edzis mell\u00e9kvesek\u00e9reg carcinom\u00e1ban<\/a><\/li>\n
  5. phaeochromocytom\u00e1k \u00e9s neuroblastom\u00e1k bioinformatikai elemz\u00e9se<\/a><\/li>\n
  6. \u00d6sszefoglal\u00f3 cikk a nem k\u00f3dol\u00f3 RNS-ek jelent\u0151s\u00e9g\u00e9r\u0151l mell\u00e9kvesek\u00e9reg carcinom\u00e1ban<\/a><\/li>\n
  7. a 9-cisz retinsav hat\u00e1sa mell\u00e9kvesek\u00e9reg carcinom\u00e1ban (xenograft vizsg\u00e1lat)<\/a><\/li>\n
  8. Egy \u00e9s k\u00e9toldali primer hyperaldosteronismus elk\u00fcl\u00f6n\u00edt\u00e9se kering\u0151 mikroRNS-ekkel<\/a><\/li>\n<\/ol>\n

    Neuroendokrin daganatok<\/strong><\/p>\n

    Az ENETS Kiv\u00e1l\u00f3s\u00e1gi Centrumhoz kapcsol\u00f3d\u00f3 neuroendokrin daganatok ter\u00e9n v\u00e9gzett kutat\u00e1sok szervez\u00e9se most indul. Ezek egy r\u00e9sze klinikai, ill. Prof. Igaz P\u00e9ter nem k\u00f3dol\u00f3 RNS vizsg\u00e1lataihoz kapcsol\u00f3dnak.<\/p>\n

    Multiplex endokrin neoplasia szindr\u00f3m\u00e1k<\/strong><\/p>\n

    E ritka \u00f6r\u00f6kl\u0151d\u0151 genetikai megbeteged\u00e9sek genetikai vizsg\u00e1lata a tansz\u00e9k \u00e9rdekl\u0151d\u00e9s\u00e9nek egyik f\u00f3kusza. T\u00f6bb \u00faj genetikai elt\u00e9r\u00e9st \u00edrtak le az elm\u00falt \u00e9vekben.<\/p>\n","protected":false},"excerpt":{"rendered":"

    Az Endokrinol\u00f3giai Tansz\u00e9k Kutat\u00e1si tev\u00e9kenys\u00e9ge az endokrinol\u00f3gia sz\u00e9les ter\u00fclet\u00e9t \u00f6leli fel. Mell\u00e9kvese daganatok Prof. Igaz P\u00e9ter kutat\u00e1sainak k\u00f6z\u00e9ppontj\u00e1ban, els\u0151sorban a mell\u00e9kvese-daganatok g\u00e9nexpresszi\u00f3s vizsg\u00e1latait, mikroRNS-ek kutat\u00e1s\u00e1t v\u00e9gzi \u00faj biomarkerek \u00e9s potenci\u00e1lis \u00faj kezel\u00e9si lehet\u0151s\u00e9gek ir\u00e1ny\u00e1ban. A kutat\u00f3csoport az els\u0151k k\u00f6z\u00f6tt \u00edrta le a mell\u00e9kvesek\u00e9reg \u00e9s mell\u00e9kvesevel\u0151 daganatok mikroRNS expresszi\u00f3s mint\u00e1zat\u00e1t \u00e9s mell\u00e9kvesek\u00e9reg carcinom\u00e1ban els\u0151k\u00e9nt v\u00e9gzett funkcion\u00e1lis …<\/p>\n","protected":false},"author":101302,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"footnotes":""},"categories":[],"tags":[],"class_list":["post-133","page","type-page","status-publish","hentry"],"acf":[],"_links":{"self":[{"href":"https:\/\/semmelweis.hu\/endokrinologia\/wp-json\/wp\/v2\/pages\/133","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/semmelweis.hu\/endokrinologia\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/semmelweis.hu\/endokrinologia\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/semmelweis.hu\/endokrinologia\/wp-json\/wp\/v2\/users\/101302"}],"replies":[{"embeddable":true,"href":"https:\/\/semmelweis.hu\/endokrinologia\/wp-json\/wp\/v2\/comments?post=133"}],"version-history":[{"count":10,"href":"https:\/\/semmelweis.hu\/endokrinologia\/wp-json\/wp\/v2\/pages\/133\/revisions"}],"predecessor-version":[{"id":422,"href":"https:\/\/semmelweis.hu\/endokrinologia\/wp-json\/wp\/v2\/pages\/133\/revisions\/422"}],"wp:attachment":[{"href":"https:\/\/semmelweis.hu\/endokrinologia\/wp-json\/wp\/v2\/media?parent=133"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/semmelweis.hu\/endokrinologia\/wp-json\/wp\/v2\/categories?post=133"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/semmelweis.hu\/endokrinologia\/wp-json\/wp\/v2\/tags?post=133"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}