{"id":16604,"date":"2026-01-20T16:06:06","date_gmt":"2026-01-20T15:06:06","guid":{"rendered":"https:\/\/semmelweis.hu\/corefacility\/?page_id=16604"},"modified":"2026-01-20T16:16:40","modified_gmt":"2026-01-20T15:16:40","slug":"advanced-peptide-and-foldamer-discovery-platform","status":"publish","type":"page","link":"https:\/\/semmelweis.hu\/corefacility\/home\/advanced-peptide-and-foldamer-discovery-platform\/","title":{"rendered":"Advanced Peptide and Foldamer Discovery Platform"},"content":{"rendered":"<div class=\"keretes\" style=\"width: 40% !important;border-left: 6px solid #4d9de0 !important\">\n<p><strong>Head of Core Facility<br \/>\n<\/strong>Istv\u00e1n M\u00e1ndity Dr.<br \/>\nGy\u00f6rgy Tibor Balogh Prof. Dr..<\/p>\n<p><strong>Core Facility Address<br \/>\n<\/strong>Department of Organic Chemistry<br \/>\nH-1092 Budapest, <br \/>\nH\u0151gyes Endre u. 7-9.<\/p>\n<p><strong>Contact E-mail<br \/>\n<\/strong><a href=\"peptide.medchem@semmelweis.hu\">peptide.medchem@semmelweis.hu<\/a> <\/p>\n<p><strong>Staff<br \/>\n<\/strong>5<\/p>\n<p><strong>Quality Control<br \/>\n<\/strong>ISO9001<\/p>\n<\/div>\n<h4><strong>What we offer<\/strong><\/h4>\n<ul style=\"list-style-type: square\">\n<li>Peptide &amp; Foldamer Design: Rational modeling for membrane activity, ion transport, and molecular recognition.<\/li>\n<li>Synthesis &amp; Optimization: High-throughput solid-phase libraries (stapled, \u03b2-peptides, hybrids) with scalable, green options.<\/li>\n<li>Characterization: CD, NMR, HPLC-MS, and biophysical analysis of structure, stability, and binding.<\/li>\n<li>Structure\u2013Function Platform: Sequence\u2013activity exploration to fine-tune properties.<\/li>\n<li>Collaboration: R&amp;D support for peptide-based tools, therapeutics, and materials.<\/li>\n<\/ul>\n<h4><strong>Why work with us<\/strong><\/h4>\n<p style=\"text-align: justify\">Our platform combines deep expertise in peptide and foldamer science with advanced capabilities in design, synthesis, and characterization. We offer tailored solutions, rapid project execution, and a collaborative mindset to accelerate your innovation pipeline. Whether you&#8217;re targeting therapeutic leads, functional biomaterials, or novel molecular architectures, we provide precision, creativity, and reliability\u2014backed by a strong track record of academic and industrial partnerships.\u00a0<\/p>\n<h4><strong>Our equipment<\/strong><\/h4>\n<ul style=\"list-style-type: square\">\n<li>Varian Mercury Plus 400 MHz NMR spectrometer\u00a0<\/li>\n<li>Shimadzu LCMS-2020\u00a0\u00a0<\/li>\n<li>CEM MW reactor\u00a0\u00a0<\/li>\n<li>Continuous flow peptide synthesis reactor\u00a0\u00a0<\/li>\n<li>Schr\u00f6dinger computational platform: Desmond, Jaguar, Maestro, Prime, PrimeX, PyMOL\u00a0\u00a0<\/li>\n<li>Gilson preparative HPLC purifcation system<\/li>\n<\/ul>\n<h4><strong>References<\/strong><\/h4>\n<ul style=\"list-style-type: square\">\n<li>Our collaborating partners: Targetex, Pharmahungary\u00a0<\/li>\n<li><a href=\"http:\/\/doi.org\/10.1038\/s41467-024-47708-4\">doi.org\/10.1038\/s41467-024-47708-4\u00a0<\/a><\/li>\n<li><a href=\"http:\/\/doi.org\/10.1111\/bph.15509\">doi.org\/10.1111\/bph.15509<\/a>\n<\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"<p>Head of Core Facility Istv\u00e1n M\u00e1ndity Dr. Gy\u00f6rgy Tibor Balogh Prof. Dr.. Core Facility Address Department of Organic Chemistry H-1092 Budapest, H\u0151gyes Endre u. 7-9. Contact E-mail <a href=\"peptide.medchem@semmelweis.hu\">peptide.medchem@semmelweis.hu<\/a> Staff 5 Quality Control ISO9001 What we offer Peptide &amp; Foldamer Design: Rational modeling for membrane activity, ion transport, and molecular recognition. Synthesis &amp; Optimization: High-throughput solid-phase libraries &hellip;<\/p>\n","protected":false},"author":101961,"featured_media":0,"parent":14502,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"template-fullwidth.php","meta":{"_acf_changed":false,"footnotes":""},"categories":[15,37],"tags":[],"class_list":["post-16604","page","type-page","status-publish","hentry","category-core-facility","category-medicinal-chemistry"],"acf":[],"_links":{"self":[{"href":"https:\/\/semmelweis.hu\/corefacility\/wp-json\/wp\/v2\/pages\/16604","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/semmelweis.hu\/corefacility\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/semmelweis.hu\/corefacility\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/semmelweis.hu\/corefacility\/wp-json\/wp\/v2\/users\/101961"}],"replies":[{"embeddable":true,"href":"https:\/\/semmelweis.hu\/corefacility\/wp-json\/wp\/v2\/comments?post=16604"}],"version-history":[{"count":3,"href":"https:\/\/semmelweis.hu\/corefacility\/wp-json\/wp\/v2\/pages\/16604\/revisions"}],"predecessor-version":[{"id":16608,"href":"https:\/\/semmelweis.hu\/corefacility\/wp-json\/wp\/v2\/pages\/16604\/revisions\/16608"}],"up":[{"embeddable":true,"href":"https:\/\/semmelweis.hu\/corefacility\/wp-json\/wp\/v2\/pages\/14502"}],"wp:attachment":[{"href":"https:\/\/semmelweis.hu\/corefacility\/wp-json\/wp\/v2\/media?parent=16604"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/semmelweis.hu\/corefacility\/wp-json\/wp\/v2\/categories?post=16604"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/semmelweis.hu\/corefacility\/wp-json\/wp\/v2\/tags?post=16604"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}