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Biochemistry 3 – dental – 2018/2019



  • Tuesday 13:10-14:20 Szent-Györgyi Albert lecture hall
  • Thursday 08:00-09:10 Szent-Györgyi Albert lecture hall

Lecturers: Tretter, László MD, PhD, DSc; Kolev, Kraszimir MD, PhD, DSc; Csanády, László MD, PhD, DSc; Törőcsik, Beáta MD, PhD

Week Date Topic
01 2019.02.05 Metabolism of red blood cells. Red blood cell enzymopathies
  2019.02.07 Metabolism of muscle and heart
02 2019.02.12 Metabolic characteristics of brain and adipose tissue. Metabolism of lymphocytes and intestinal epithel cells
  2019.02.14 Reseach Students’ Conference
03 2019.02.19 The starving-feed cyclus and its regulation. Regulattion of hepatocyte metabolism in starvation
  2019.02.21* ChREBP signal transduction. The role of the SREBP, mTOR and PPAR system in the regulation of metabolism
 04 2019.02.26* AMP kinase, PGC1-a, HIF, p53. The role of thyroid hormones 
  2019.02.28 Na+,K+ ATP-ase. The permeability of cell membranes, P-type ATP-ase. Structure of Na+,K+ ATP-ase, Na+,K+ ATP-ase isoforms. Regulation. Secondary active transports. Na-H exchange 
05 2019.03.05 Chemical neurotransmission. Cholinergic neurotransmission. Biosynthesis of acetylcholine. receptors, acetylcholine esterase. Molecular mechanism of exocytosis
  2019.03.07 Noradrenerg neurotransmission. Synthesis and metabolism of norepinephrine. Synaptic uptake.
06 2019.03.12 Adrenerg receptors. Molecular mechanism of epinephrine and norepinephrine on various organs
  2019.03.14 Dopaminergic and serotoninergic neurotransmission. Synthesis, transporters, receptors. Biochemistry of Parkinson disease
07 2019.03.19 Glutamatergic neurotransmission
  2019.03.21 NO: Regulatory role of NO. Nitric oxide synthase. Guanylate cyclase. Molecular effects of nitric oxide
08  2019.03.26* General properties of ion channels. Methods for studying ion channels. Molecular mechanisms of gating and permeation. Structure of K+ channels. (LCs)
  2019.03.28* Molecular diversity of ion channels. Voltage-gated K+ channels. ATP-sensitive K+ channels. Voltage-gated Cl- channels. The CFTR chloride channel. The nicotinic Acetylcholine Receptor. (LCS)
09 2019.04.02 General overview of blood clot formation and elimination. Fibrinogen and fibrin. Prothrombin activation and regulation of thrombin activity. Triggers of blood clotting, amplification of the initiation. (KK)
  2019.04.04 Inhibitors  of blood coagulation and  negative feedback mechanisms  (KK)
10 2019.04.09 Fibrinolysis. Activation of plasminogen. Inhibitors of plasmin  (KK)
  2019.04.11 Cellular elements of the haemostatic system. Platelets and von Willebrand factor  (KK)
    Spring break, Eastern
11 2019.04.23 Neutrophils and endothelial cells in haemostasis.  (KK)
  2019.04.25 Haemodynamical and biochemical interactions in haemostasis  (KK)
12 2019.04.30 Faculty Day (FD)
  2019.05.02* The role of endothelial dysfunction in atherosclerosis. LDL oxidation and   pattern-recognition receptors (TLR, scavenger receptors). Cholesterol induced pyroptosis   (KK)
13 2019.05.07* Effect of cholesterol on  atherosclerotic  plaque formation. Risk factors of atherosclerosis related to cholesterol homeostasis (diabetes, hypertriglyceridemia). Biochemical background of atherosclerosis, prevention)
  2019.05.09* Signaltransduction-1: Therapeutic targeting of signal transduction pathways (TB)
14 2019.05.14* Signaltransduction-2: Cytokine signaling. Jak-STAT pathway. Calcium signaling. Nuclear receptors. (TB)
  2019.05.16* Signaltransduction-3: Wnt signal transduction pathways. Frizzled/Arrow/LRP receptors, Dsh, axin, APC proteins, GSK3, CK1α protein kinases, protein phosphatases (PP2A) and the ubiquitin system. Notch receptor signaling (TB)

*facultative lectures held for dentistry students


Laboratory and seminar lessons in spring semester of the 2018/2019 academic year

Day Time Group Lab teacher
Wednesday 08:00-10:30 ED01 Vér, Ágota 1
Wednesday 08:00-10:30 ED02 Vér, Ágota 1
Wednesday 08:00-10:30 ED03 Végh, Miklós 2
Wednesday 08:00-10:30 ED04 Végh, Miklós 2
Wednesday 08:00-10:30 ED05 Bak, Judit 3

Laboratory lessons

Laboratory lessons and seminars are held at laboratory rooms of the Deparment (EOK-Building, Budapest IX., Tűzoltó utca 37-47. H-1094, 1st floor, passage ‘C’)

01 2019.02.06 F1-2-3-4-5 Metabolism of excercise (sem)
02 2019.02.13    
03 2019.02.20 F1-2-3-4-5 Determination of transaminase enzyme activity. (lab) Determination of serum creatine kinase activity (lab)
04 2019.02.27    
05 2019.03.06 F1-2-3-4-5 Extracellular matrix (sem)
06 2019.03.13 F1-2-3-4-5 First midterm exam
07 2019.03.20 F1-2-3-4-5 Acute and chronic liver disease (sem)
08 2019.03.27 F1-2-3-4-5 Retake of first midterm exam
09 2019.04.03 F1-2-3-4-5 Determination of blood glucose level; In vitro determination of hemoglobin 1Ac (lab)
10 2019.04.10 F1-2-3-4-5 Second midterm exam
11 2019.04.24 F1-2-3-4-5 Experimental models of blood coagulation (lab)
12 2019.05.01 F1-2-3-4-5 MAY DAY – Retake of second midterm exam. Date, time, location is published later
13 2019.05.08 F1-2-3-4-5 Haemostatic abnormalities 1-2 (sem) 
14 2019.05.15 F1-2-3-4-5 Second retake exam of mirterm exams#1 and #2


Recommended books

  • Harper’s Illustrated Biochemistry (31st edition)
  • Powerpoint files of lectures 
  • Consultation manual 
  • Students’ own notes
  • Ask your laboratory teacher for the username and password of our authorized pages

Midterm exams

  • 1st midterm exam: 13th of March, 2019; 08:00-10:30
  • 2nd midterm exam: 10th of April, 2019; 08:00-10:30 
  • Retake of 1st midterm exam: 27th of March, 2019; 08:00-10:30
  • Retake of 2nd midterm exam: date and location is published later 
  • 2nd retake of the 1st and 2nd midterm exams: 15th of May, 2019; 08:00-10:30 

Topic lists and condition of the midterm exams


Dental Biochemistry 3 competition is held on the 14th week:

May 13, 2019 at 17:30, Szent-Györgyi Albert lecture hall and 17:40, Hevesy György lecture hall for dentistry students.


Material: lectures, seminars and laboratory lessons of the fall and spring semesters of 2018/2019 and spring semester of the 2017/2018 academic year
Test: biochemistry problems and structures (max. 30 + 10) + 70 multiple choice type questions
Students reaching at least 75 % will be exempted from the examination by mark 5
Other exemptions are not possible

  • grade 3 or better at both midterms
  • registration for the subject matter of Dental Biochemistry 3 in the spring semester of 2018/2019 academic year
  • registration for the subject matter of Dental Biochemistry 2 in the fall semester of 2018/2019 academic year
  • registration for the subject matter of Dental Biochemistry 1 in the fall semester of 2017/2018  academic year

Registration: May 8-10, 2019

Topic list

Final examination

Course-outline: Dental Biochemistry 3

Spring semester of 2018/2019 academic year

Head of Deparment of Medical Biochemistry: Prof. Tretter, László MD, PhD, DSc

  • Subject title: Dental biochemistry 3
  • Faculty: Dentistry
  • Code: FOKOOBI204_3A
  • Credit: 3
Student office of Department of Medical Biochemistry
Budapest IX., Tűzoltó utca 37-47 H-1094; ROOM: 1.508
+36-1-459-1500#60061;  +36-20-666-60061
Office hours: Tuesday, Wednesday, Thursday – 10:00-12:00
Course-coordinator for medical biochemistry 1-2-3, dental biochemistry 1-2-3 students:
István Léránt PhD., +36-20-663-2267
Mr. Zsolt Ozsváth Mrs Vera Pichler
+36-20-666-0061 +36-20-666-0061
medical & dental biochemistry 3 medical & dental biochemistry 1
medical & dental biochemistry 2  

“English Secretariate”

Dentistry students Medical students
Mrs Borbála Hanek Adrienn Bácskai
+36-20-666-0479 +36-20-666-0072
Dental biochemistry 2-3 Medical biochemistry 2-3
Dental biochemistry 1 Éva Kiss
  Medical biochemistry 1

e-Lectures, e-Laboratory lessons, e-Seminars