{"id":9002,"date":"2023-03-20T14:00:52","date_gmt":"2023-03-20T13:00:52","guid":{"rendered":"https:\/\/semmelweis.hu\/bioinformatika\/?p=9002"},"modified":"2023-04-03T10:42:50","modified_gmt":"2023-04-03T08:42:50","slug":"megjelent-dr-bartha-aron-kozlemenye-az-international-journal-of-molecular-sciences-folyoiratban","status":"publish","type":"post","link":"https:\/\/semmelweis.hu\/bioinformatika\/megjelent-dr-bartha-aron-kozlemenye-az-international-journal-of-molecular-sciences-folyoiratban\/","title":{"rendered":"Megjelent Dr. Bartha \u00c1ron k\u00f6zlem\u00e9nye az International Journal of Molecular Sciences foly\u00f3iratban"},"content":{"rendered":"<p><img loading=\"lazy\" decoding=\"async\" class=\" wp-image-9044 alignleft\" src=\"https:\/\/semmelweis.hu\/bioinformatika\/files\/2023\/03\/ijmslogosocial_300_254.jpg\" alt=\"\" width=\"332\" height=\"281\" \/>A tansz\u00e9k\u00fcnk\u00f6n v\u00e9gzett kutat\u00e1s a tumor \u00e9s a hozz\u00e1tartoz\u00f3 norm\u00e1l sz\u00f6vetek \u00f6sszehasonl\u00edt\u00f3 vizsg\u00e1lat\u00e1val a vil\u00e1gos sejtes veser\u00e1kok proteotranszkriptomikai anal\u00edzis\u00e9nek eredm\u00e9nyeit foglalja \u00f6ssze. A daganatos sz\u00f6vetekben \u00f6sszesen 20 g\u00e9n expresszi\u00f3ja mutatott szignifik\u00e1ns elt\u00e9r\u00e9st valamennyi vizsg\u00e1lt kohortban, melyek egy r\u00e9sze \u00f6sszef\u00fcgg\u00e9st mutatott a veser\u00e1kok r\u00f6videbb t\u00fal\u00e9l\u00e9s\u00e9vel is. V\u00e9g\u00fcl 9 olyan g\u00e9n (ANXA1, CCND1, IGFBP3, P4HA1, PFKP, PLIN2, PLOD2, VEGFA \u00e9s VIM) ker\u00fclt egy SVM (support vector machine) alap\u00fa modellbe, mely k\u00e9pes a norm\u00e1l \u00e9s rosszindulat\u00fa tumor sz\u00f6vetek protein alap\u00fa megk\u00fcl\u00f6nb\u00f6ztet\u00e9s\u00e9re. A bemutatott g\u00e9npanel \u00edg\u00e9retesen haszn\u00e1lhat\u00f3 klinikai k\u00f6rnyezetben is.<\/p>\n<div>\n<div dir=\"auto\">\n<div dir=\"auto\">\n<div dir=\"auto\">Dr. Bartha \u00c1ron teljes cikke, melynek c\u00edme \u201cProteotranscriptomic discrimination of tumor and normal tissues in renal cell carcinoma\u201d<a href=\"https:\/\/www.mdpi.com\/1422-0067\/24\/5\/4488\">\u00a0<u>ide<\/u><\/a><span style=\"font-size: 1rem\"> kattintva \u00e9rhet\u0151 el.<\/span><\/div>\n<\/div>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>A tansz\u00e9k\u00fcnk\u00f6n v\u00e9gzett kutat\u00e1s a tumor \u00e9s a hozz\u00e1tartoz\u00f3 norm\u00e1l sz\u00f6vetek \u00f6sszehasonl\u00edt\u00f3 vizsg\u00e1lat\u00e1val a vil\u00e1gos sejtes veser\u00e1kok proteotranszkriptomikai anal\u00edzis\u00e9nek eredm\u00e9nyeit foglalja \u00f6ssze. A daganatos sz\u00f6vetekben \u00f6sszesen 20 g\u00e9n expresszi\u00f3ja mutatott szignifik\u00e1ns elt\u00e9r\u00e9st valamennyi vizsg\u00e1lt kohortban, melyek egy r\u00e9sze \u00f6sszef\u00fcgg\u00e9st mutatott a veser\u00e1kok r\u00f6videbb t\u00fal\u00e9l\u00e9s\u00e9vel is. V\u00e9g\u00fcl 9 olyan g\u00e9n (ANXA1, CCND1, IGFBP3, P4HA1, PFKP, PLIN2, &hellip;<\/p>\n","protected":false},"author":102018,"featured_media":9043,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[2],"tags":[],"class_list":["post-9002","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-hirek"],"acf":[],"_links":{"self":[{"href":"https:\/\/semmelweis.hu\/bioinformatika\/wp-json\/wp\/v2\/posts\/9002","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/semmelweis.hu\/bioinformatika\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/semmelweis.hu\/bioinformatika\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/semmelweis.hu\/bioinformatika\/wp-json\/wp\/v2\/users\/102018"}],"replies":[{"embeddable":true,"href":"https:\/\/semmelweis.hu\/bioinformatika\/wp-json\/wp\/v2\/comments?post=9002"}],"version-history":[{"count":6,"href":"https:\/\/semmelweis.hu\/bioinformatika\/wp-json\/wp\/v2\/posts\/9002\/revisions"}],"predecessor-version":[{"id":9046,"href":"https:\/\/semmelweis.hu\/bioinformatika\/wp-json\/wp\/v2\/posts\/9002\/revisions\/9046"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/semmelweis.hu\/bioinformatika\/wp-json\/wp\/v2\/media\/9043"}],"wp:attachment":[{"href":"https:\/\/semmelweis.hu\/bioinformatika\/wp-json\/wp\/v2\/media?parent=9002"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/semmelweis.hu\/bioinformatika\/wp-json\/wp\/v2\/categories?post=9002"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/semmelweis.hu\/bioinformatika\/wp-json\/wp\/v2\/tags?post=9002"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}