Number of vaccines administered at Semmelweis University - 07 March 2021
67447 Total vaccines
10872 Semmelweis Citizens vaccinated

2014-2015, ősz (AOVHUM084_1A)



Introduction to the underlying molecular mechanisms of human development and malformations. Revealing examples of environmental effects on pregnancy. Studying the formation of normal adult anatomy.

Main topics:
  • Introduction to developmental biology and its substantiality in medicine
  • Tools of experimental embryology
  • Regulatory mechanisms of ontogenesis: maternal effect, polarisation, homeobox genes, transcription factors, epigenetic effects, role of extracellular factors (growth factors, extracellular matrix, basal membrane) in cellular differentiation, cell migration
  • Stem cell biology and regeneration
  • Germline determination, oogenesis
  • Teratogenesis
  • Axis formation


1 Regulatory mechanisms of ontogenesis I. (Krisztina Herberth-Minkó) 2014.09.25. letöltés
2 Regulatory mechanisms of ontogenesis II. (Krisztina Herberth-Minkó) 2014.10.02. letöltés
3 Regulatory mechanism of ontogenesis III. (Krisztina Herberth-Minkó) 2014.10.09. letöltés
4 ECM, basal lamina-cell migration, epithelial morphogenesis and branching (Katalin Kocsis) 2014.10.16. letöltés
5 Stem cells (Katalin Kocsis) 2014.11.06. letöltés
6 Fertilization and Cleavage (Nóra Pecsenye-Fejszák) 2014.11.13. letöltés
7 Early development, cleavage, gastrulation (Katalin Kocsis) 2014.11.20. letöltés
8 Axis formation: anterior-posterior and dorsal-ventral patterning (Ildikó Bódi) 2014.11.27. letöltés
9 Epithelial morphogenezis (Ildikó Bódi) 2014.12.04. letöltés


Tematika, órarend (2014-2015)

Topic list 2017.01.26.

Exam topics

Developmental Biology I. course

2014/2015. year 1st semester

Topics of the exam

1. Stem cell biology, types of stem cells. Induced pluripotent stem cells.

2. Teratogenesis.

3. Genetic hierarchy of early developmental events from Drosophila to mammals (maternal-effect genes, gap genes, pair-rule genes, segment-polarity genes, homeotic selector genes).

4. Regulatory mechanisms of ontogenesis II: signal transduction pathways.

5. Regulatory mechanisms of ontogenesis III.: epigenetic influences on gene expression: DNA metilation, X chromosome inactivation, genetic imprinting; hydatidiform mole.

6. Function of ECM in the early embryo.

7. Epithelial morphogenesis.

8. Fertilization.

9. Gastrulation.

10. Axis formation.