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Intézeti publikációs lista

2018

  1. Agg B., Baranyai T., Makkos A., Veto B., Farago N., Zvara A., Giricz Z., Veres D. V., Csermely P., Aranyi T., Puskas L. G., Varga Z. V., Ferdinandy P.: Author Correction: MicroRNA interactome analysis predicts post-transcriptional regulation of ADRB2 and PPP3R1 in the hypercholesterolemic myocardium. Sci Rep, 2018, 8:12159
  2. Agg B., Baranyai T., Makkos A., Veto B., Farago N., Zvara A., Giricz Z., Veres D. V., Csermely P., Aranyi T., Puskas L. G., Varga Z. V., Ferdinandy P.: MicroRNA interactome analysis predicts post-transcriptional regulation of ADRB2 and PPP3R1 in the hypercholesterolemic myocardium. Sci Rep, 2018, 8:10134
  3. Angyal N., Horvath E. Z., Tarnok Z., Richman M. J., Bognar E., Lakatos K., Sasvari-Szekely M., Nemoda Z.: Association analysis of norepinephrine transporter polymorphisms and methylphenidate response in ADHD patients. Prog Neuropsychopharmacol Biol Psychiatry, 2018, 84:122-128
  4. Barna J., Csermely P., Vellai T.: Roles of heat shock factor 1 beyond the heat shock response. Cell Mol Life Sci, 2018, 75:2897-2916
  5. Bhola T., Kapuy O., Vinod P. K.: Computational modelling of meiotic entry and commitment. Sci Rep, 2018, 8:180
  6. Csermely P.: A demokrácia, mint a túlélés többmilliárd éves eszköze. Magyar Tudomány, 2018, 179:615-623
  7. Csermely P.: The Wisdom of Networks: A General Adaptation and Learning Mechanism of Complex Systems: The Network Core Triggers Fast Responses to Known Stimuli; Innovations Require the Slow Network Periphery and Are Encoded by Core-Remodeling. Bioessays, 2018, 40:1700150
  8. Di Sante J., Ismaylova E., Nemoda Z., Gouin J. P., Yu W. J., Caldwell W., Vitaro F., Szyf M., Tremblay R. E., Booij L.: Peripheral DNA methylation of HPA axis-related genes in humans: Cross-tissue convergence, two-year stability and behavioural and neural correlates. Psychoneuroendocrinology, 2018, 97:196-205
  9. Ditengou F. A., Gomes D., Nziengui H., Kochersperger P., Lasok H., Medeiros V., Paponov I. A., Nagy S. K., Nadai T. V., Meszaros T., Barnabas B., Ditengou B. I., Rapp K., Qi L., Li X., Becker C., Li C., Doczi R., Palme K.: Characterization of auxin transporter PIN6 plasma membrane targeting reveals a function for PIN6 in plant bolting. New Phytol, 2018, 217:1610-1624
  10. Dory M., Hatzimasoura E., Kallai B. M., Nagy S. K., Jager K., Darula Z., Nadai T. V., Meszaros T., Lopez-Juez E., Barnabas B., Palme K., Bogre L., Ditengou F. A., Doczi R.: Coevolving MAPK and PID phosphosites indicate an ancient environmental control of PIN auxin transporters in land plants. FEBS Lett, 2018, 592:89-102
  11. Dulk M., Szeder B., Glatz G., Mero B. L., Koprivanacz K., Kudlik G., Vas V., Sipeki S., Cserkaszky A., Radnai L., Buday L.: EGF Regulates the Interaction of Tks4 with Src through Its SH2 and SH3 Domains. Biochemistry, 2018, 57:4186-4196
  12. Farrell C., Doolin K., N O. L., Jairaj C., Roddy D., Tozzi L., Morris D., Harkin A., Frodl T., Nemoda Z., Szyf M., Booij L., O’Keane V.: DNA methylation differences at the glucocorticoid receptor gene in depression are related to functional alterations in hypothalamic-pituitary-adrenal axis activity and to early life emotional abuse. Psychiatry Res, 2018, 265:341-348
  13. Gyulavari P., Szokol B., Szabadkai I., Brauswetter D., Banhegyi P., Varga A., Marko P., Boros S., Illyes E., Szantai-Kis C., Kreko M., Czudor Z., Orfi L.: Discovery and optimization of novel benzothiophene-3-carboxamides as highly potent inhibitors of Aurora kinases A and B. Bioorg Med Chem Lett, 2018, 28:3265-3270
  14. Holczer M., Besze B., Zambo V., Csala M., Banhegyi G., Kapuy O.: Epigallocatechin-3-Gallate (EGCG) Promotes Autophagy-Dependent Survival via Influencing the Balance of mTOR-AMPK Pathways upon Endoplasmic Reticulum Stress. Oxid Med Cell Longev, 2018, 2018:6721530
  15. Kapuy O., Papp D., Vellai T., Banhegyi G., Korcsmaros T.: Systems-Level Feedbacks of NRF2 Controlling Autophagy upon Oxidative Stress Response. Antioxidants (Basel), 2018, 7:E39
  16. Kapuy O., Vinod P. K., Banhegyi G., Novak B.: Systems-level feedback regulation of cell cycle transitions in Ostreococcus tauri. Plant Physiol Biochem, 2018, 126:39-46
  17. Kenezloi E., Lakatos K., Horvath E. Z., Sasvari-Szekely M., Nemoda Z.: A pilot study of early onset obsessive-compulsive disorder: Symptom dimensions and association analysis with polymorphisms of the serotonin transporter gene. Psychiatry Res, 2018, 268:388-391
  18. Kovacs-Nagy R., Morin G., Nouri M. A., Brandau O., Saadi N. W., Nouri M. A., van den Broek F., Prokisch H., Mayr J. A., Wortmann S. B.: HTRA2 Defect: A Recognizable Inborn Error of Metabolism with 3-Methylglutaconic Aciduria as Discriminating Feature Characterized by Neonatal Movement Disorder and Epilepsy-Report of 11 Patients. Neuropediatrics, 2018, 49:373-378
  19. Kovacs K., Viranyi Z., Kis A., Turcsan B., Hudecz A., Marmota M. T., Koller D., Ronai Z., Gacsi M., Topal J.: Dog-Owner Attachment Is Associated With Oxytocin Receptor Gene Polymorphisms in Both Parties. A Comparative Study on Austrian and Hungarian Border Collies. Front Psychol, 2018, 9:435
  20. Mandl J., Banhegyi G.: The ER – Glycogen Particle – Phagophore Triangle: A Hub Connecting Glycogenolysis and Glycophagy? Pathol Oncol Res, 2018, 24:821-826
  21. Marton M., Tihanyi N., Gyulavari P., Banhegyi G., Kapuy O.: NRF2-regulated cell cycle arrest at early stage of oxidative stress response mechanism. PLoS One, 2018, 13:e0207949
  22. Nguyen M. T., Somogyvari M., Soti C.: Hsp90 Stabilizes SIRT1 Orthologs in Mammalian Cells and C. elegans. Int J Mol Sci, 2018, 19:E3661
  23. Ronai Z., Lippai Z., Elek Z., Somogyi A.: [Investigation of the genetic background of complex diseases]. Orv Hetil, 2018, 159:1254-1261
  24. Somogyvari M., Gecse E., Soti C.: DAF-21/Hsp90 is required for C. elegans longevity by ensuring DAF-16/FOXO isoform A function. Sci Rep, 2018, 8:12048
  25. Szabadkai I., Torka R., Garamvolgyi R., Baska F., Gyulavari P., Boros S., Illyes E., Choidas A., Ullrich A., Orfi L.: Discovery of N-[4-(Quinolin-4-yloxy)phenyl]benzenesulfonamides as Novel AXL Kinase Inhibitors. J Med Chem, 2018, 61:6277–6292
  26. Szabo A., Sumegi K., Fekete K., Hocsak E., Debreceni B., Setalo G., Jr., Kovacs K., Deres L., Kengyel A., Kovacs D., Mandl J., Nyitrai M., Febbraio M. A., Gallyas F., Jr., Sumegi B.: Activation of mitochondrial fusion provides a new treatment for mitochondria-related diseases. Biochem Pharmacol, 2018, 150:86-96
  27. Szakacs Z., Meszaros T., de Jonge M. I., Gyurcsanyi R. E.: Selective counting and sizing of single virus particles using fluorescent aptamer-based nanoparticle tracking analysis. Nanoscale, 2018, 10:13942-13948
  28. Westphal D. S., Riedhammer K. M., Kovacs-Nagy R., Meitinger T., Hoefele J., Wagner M.: A De Novo Missense Variant in POU3F2 Identified in a Child with Global Developmental Delay. Neuropediatrics, 2018, 49:401-404

2017

  1. Adami H. O., Csermely P., Veres D. V., Emilsson L., Loberg M., Bretthauer M., Kalager M.: Are rapidly growing cancers more lethal? Eur J Cancer, 2017, 72:210-214
  2. Banlaki Z., Cimarelli G., Viranyi Z., Kubinyi E., Sasvari-Szekely M., Ronai Z.: DNA methylation patterns of behavior-related gene promoter regions dissect the gray wolf from domestic dog breeds. Mol Genet Genomics, 2017, 292:685-697
  3. Bence M., Marx P., Szantai E., Kubinyi E., Ronai Z., Banlaki Z.: Lessons from the canine Oxtr gene: populations, variants and functional aspects. Genes Brain Behav, 2017, 16:427-438
  4. Brauswetter D., Birtalan E., Danos K., Kocsis A., Krenacs T., Timar J., Mihalyi R., Horcsik D., Polony G., Tamas L., Petak I.: p16(INK4) expression is of prognostic and predictive value in oropharyngeal cancers independent of human papillomavirus status: a Hungarian study. Eur Arch Otorhinolaryngol, 2017, 274:1959-1965
  5. Brauswetter D., Gurbi B., Varga A., Varkondi E., Schwab R., Banhegyi G., Fabian O., Keri G., Valyi-Nagy I., Petak I.: Molecular subtype specific efficacy of MEK inhibitors in pancreatic cancers. PLoS One, 2017, 12:e0185687
  6. Cimarelli G., Viranyi Z., Turcsan B., Ronai Z., Sasvari-Szekely M., Banlaki Z.: Social Behavior of Pet Dogs Is Associated with Peripheral OXTR Methylation. Front Psychol, 2017, 8:549
  7. Csermely P.: The Network Concept of Creativity and Deep Thinking: Applications to Social Opinion Formation and Talent Support. Gifted Child Quart, 2017, 61:194-201
  8. Ekins S., Godbole A. A., Keri G., Orfi L., Pato J., Bhat R. S., Verma R., Bradley E. K., Nagaraja V.: Machine learning and docking models for Mycobacterium tuberculosis topoisomerase I. Tuberculosis (Edinb), 2017, 103:52-60
  9. Freytag V., Probst S., Hadziselimovic N., Boglari C., Hauser Y., Peter F., Gabor Fenyves B., Milnik A., Demougin P., Vukojevic V., de Quervain D. J., Papassotiropoulos A., Stetak A.: Genome-Wide Temporal Expression Profiling in Caenorhabditis elegans Identifies a Core Gene Set Related to Long-Term Memory. J Neurosci, 2017, 37:6661-6672
  10. Gamberucci A., Marcolongo P., Nemeth C. E., Zoppi N., Szarka A., Chiarelli N., Hegedus T., Ritelli M., Carini G., Willaert A., Callewaert B. L., Coucke P. J., Benedetti A., Margittai E., Fulceri R., Banhegyi G., Colombi M.: GLUT10-Lacking in Arterial Tortuosity Syndrome-Is Localized to the Endoplasmic Reticulum of Human Fibroblasts. Int J Mol Sci, 2017, 18: E1820
  11. Horvath B. M., Kourova H., Nagy S., Nemeth E., Magyar Z., Papdi C., Ahmad Z., Sanchez-Perez G. F., Perilli S., Blilou I., Pettko-Szandtner A., Darula Z., Meszaros T., Binarova P., Bogre L., Scheres B.: Arabidopsis RETINOBLASTOMA RELATED directly regulates DNA damage responses through functions beyond cell cycle control. EMBO J, 2017, 36:1261-1278
  12. Huang A. Y., Yu D., Davis L. K., Sul J. H., Tsetsos F., Ramensky V., Zelaya I., Ramos E. M., Osiecki L., Chen J. A., McGrath L. M., Illmann C., Sandor P., Barr C. L., Grados M., Singer H. S., Nothen M. M., Hebebrand J., King R. A., Dion Y., Rouleau G., Budman C. L., Depienne C., Worbe Y., Hartmann A., Muller-Vahl K. R., Stuhrmann M., Aschauer H., Stamenkovic M., Schloegelhofer M., Konstantinidis A., Lyon G. J., McMahon W. M., Barta C., Tarnok Z., Nagy P., Batterson J. R., Rizzo R., Cath D. C., Wolanczyk T., Berlin C., Malaty I. A., Okun M. S., Woods D. W., Rees E., Pato C. N., Pato M. T., Knowles J. A., Posthuma D., Pauls D. L., Cox N. J., Neale B. M., Freimer N. B., Paschou P., Mathews C. A., Scharf J. M., Coppola G., Tourette Syndrome Association International Consortium for G., Gilles de la Tourette Syndrome G. R. I.: Rare Copy Number Variants in NRXN1 and CNTN6 Increase Risk for Tourette Syndrome. Neuron, 2017, 94:1101-1111 e1107
  13. Katonai E. R., Szekely A., Vereczkei A., Sasvari-Szekely M., Banyai E. I., Varga K.: Dopaminergic and Serotonergic Genotypes and the Subjective Experiences of Hypnosis. Int J Clin Exp Hypn, 2017, 65:379-397
  14. Konstenius M., Leifman A., van Emmerik-van Oortmerssen K., van de Glind G., Franck J., Moggi F., Ramos-Quiroga J. A., Levin F. R., Carpentier P. J., Skutle A., Bu E. T., Kaye S., Demetrovics Z., Barta C., Auriecomb M., Fatseas M., Johnson B., Faraone S. V., Allsop S., Carruthers S., Schoevers R. A., Verspreet S., Dom G., Koeter M. W., van den Brink W.: Childhood trauma exposure in substance use disorder patients with and without ADHD. Addict Behav, 2017, 65:118-124
  15. Koprivanacz K., Toke O., Besztercei B., Juhasz T., Radnai L., Mero B., Mihaly J., Peter M., Balogh G., Vigh L., Buday L., Liliom K.: The SH3 domain of Caskin1 binds to lysophosphatidic acid suggesting a direct role for the lipid in intracellular signaling. Cell Signal, 2017, 32:66-75
  16. Kotyuk E., Biro V., Bircher J., Elek Z., Sasvari M., Szekely A.: ABCA1 Polymorphism, a Genetic Risk Factor of Harm Avoidance. J Individ Differ, 2017, 38:189-195
  17. Kubinyi E., Bence M., Koller D., Wan M., Pergel E., Ronai Z., Sasvari-Szekely M., Miklosi A.: Oxytocin and Opioid Receptor Gene Polymorphisms Associated with Greeting Behavior in Dogs. Front Psychol, 2017, 8:1520
  18. Legeza B., Marcolongo P., Gamberucci A., Varga V., Banhegyi G., Benedetti A., Odermatt A.: Fructose, Glucocorticoids and Adipose Tissue: Implications for the Metabolic Syndrome. Nutrients, 2017, 9:E426
  19. Lorincz T., Szarka A.: The determination of hepatic glutathione at tissue and subcellular level. J Pharmacol Toxicol Methods, 2017, 88:32-39
  20. Marton M., Kurucz A., Lizak B., Margittai E., Banhegyi G., Kapuy O.: A Systems Biological View of Life-and-Death Decision with Respect to Endoplasmic Reticulum Stress-The Role of PERK Pathway. Int J Mol Sci, 2017, 18:E58
  21. Modos D., Bulusu K. C., Fazekas D., Kubisch J., Brooks J., Marczell I., Szabo P. M., Vellai T., Csermely P., Lenti K., Bender A., Korcsmaros T.: Neighbours of cancer-related proteins have key influence on pathogenesis and could increase the drug target space for anticancer therapies. NPJ Syst Biol Appl, 2017, 3:1-13
  22. Muranyi J., Varga A., Gurbi B., Gyulavari P., Mezo G., Vantus T.: In Vitro Imaging and Quantification of the Drug Targeting Efficiency of Fluorescently Labeled GnRH Analogues. J Vis Exp, 2017, 3:E55529
  23. Nemoda Z., Szyf M.: Epigenetic Alterations and Prenatal Maternal Depression. Birth Defects Res, 2017, 109:888-897
  24. Olah K., Topal J., Kovacs K., Kis A., Koller D., Young Park S., Viranyi Z.: Gaze-Following and Reaction to an Aversive Social Interaction Have Corresponding Associations with Variation in the OXTR Gene in Dogs but Not in Human Infants. Front Psychol, 2017, 8:2156
  25. Percze K., Szakacs Z., Scholz E., Andras J., Szeitner Z., Kieboom C. H., Ferwerda G., Jonge M. I., Gyurcsanyi R. E., Meszaros T.: Aptamers for respiratory syncytial virus detection. Sci Rep, 2017, 7:42794
  26. Szeitner Z., Doleschall A., Varga M., Keltai K., Revesz K., Gyurcsanyi R. E., Meszaros T.: Spiegelmers as potential receptors for cTnI diagnostics. Anal Methods-Uk, 2017, 9:5091-5093
  27. Turcsan B., Range F., Ronai Z., Koller D., Viranyi Z.: Context and Individual Characteristics Modulate the Association between Oxytocin Receptor Gene Polymorphism and Social Behavior in Border Collies. Front Psychol, 2017, 8:2232
  28. Veto B., Bojcsuk D., Bacquet C., Kiss J., Sipeki S., Martin L., Buday L., Balint B. L., Aranyi T.: The transcriptional activity of hepatocyte nuclear factor 4 alpha is inhibited via phosphorylation by ERK1/2. PLoS One, 2017, 12:e0172020

2016

  1. Alexander J., Potamianou H., Xing J., Deng L., Karagiannidis I., Tsetsos F., Drineas P., Tarnok Z., Rizzo R., Wolanczyk T., Farkas L., Nagy P., Szymanska U., Androutsos C., Tsironi V., Koumoula A., Barta C., TsgeneSee, Sandor P., Barr C. L., Tischfield J., Paschou P., Heiman G. A., Georgitsi M.: Targeted Re-Sequencing Approach of Candidate Genes Implicates Rare Potentially Functional Variants in Tourette Syndrome Etiology. Front Neurosci, 2016, 10:428
  2. Angyal N., Halasz J., Meszaros G., Kovacs J. K., Kruk E., Nemoda Z.: Potential salivary biomarkers and their genetic effects in a pilot study of adolescent boys with externalizing problems. Neuropsychopharmacol Hung, 2016, 18:173-179
  3. Appenzeller-Herzog C., Banhegyi G., Bogeski I., Davies K. J., Delaunay-Moisan A., Forman H. J., Gorlach A., Kietzmann T., Laurindo F., Margittai E., Meyer A. J., Riemer J., Rutzler M., Simmen T., Sitia R., Toledano M. B., Touw I. P.: Transit of H2O2 across the endoplasmic reticulum membrane is not sluggish. Free Radic Biol Med, 2016, 94:157-160
  4. Balogh T., Lorincz T., Stiller I., Mandl J., Banhegyi G., Szarka A.: The Level of ALR is Regulated by the Quantity of Mitochondrial DNA. Pathol Oncol Res, 2016, 22:431-437
  5. Bertelsen B., Stefansson H., Riff Jensen L., Melchior L., Mol Debes N., Groth C., Skov L., Werge T., Karagiannidis I., Tarnok Z., Barta C., Nagy P., Farkas L., Brondum-Nielsen K., Rizzo R., Gulisano M., Rujescu D., Kiemeney L. A., Tosato S., Nawaz M. S., Ingason A., Unnsteinsdottir U., Steinberg S., Ludvigsson P., Stefansson K., Kuss A. W., Paschou P., Cath D., Hoekstra P. J., Muller-Vahl K., Stuhrmann M., Silahtaroglu A., Pfundt R., Tumer Z.: Association of AADAC Deletion and Gilles de la Tourette Syndrome in a Large European Cohort. Biol Psychiatry, 2016, 79:383-391
  6. Booij T. H., Klop M. J., Yan K., Szantai-Kis C., Szokol B., Orfi L., van de Water B., Keri G., Price L. S.: Development of a 3D Tissue Culture-Based High-Content Screening Platform That Uses Phenotypic Profiling to Discriminate Selective Inhibitors of Receptor Tyrosine Kinases. J Biomol Screen, 2016, 21:912-922
  7. Brauswetter D., Danos K., Gurbi B., Felegyhazi E. F., Birtalan E., Meggyeshazi N., Krenacs T., Tamas L., Petak I.: Copy number gain of PIK3CA and MET is associated with poor prognosis in head and neck squamous cell carcinoma. Virchows Arch, 2016, 468:579-587
  8. Brumariu L. E., Bureau J. F., Nemoda Z., Sasvari-Szekely M., Lyons-Ruth K.: Attachment and Temperament Revisited: Infant Distress, Attachment Disorganization, and the Serotonin Transporter Polymorphism. J Reprod Infant Psychol, 2016, 34:77-89
  9. Cimarelli G., Turcsan B., Banlaki Z., Range F., Viranyi Z.: Dog Owners’ Interaction Styles: Their Components and Associations with Reactions of Pet Dogs to a Social Threat. Front Psychol, 2016, 7:1979
  10. Csala M.: [Hyper-free fatty acidemia – insulin resistance and beta-cell death]. Orv Hetil, 2016, 157:733-739
  11. Csalyi K., Fazekas D., Kadlecsik T., Turei D., Gul L., Horvath B., Modos D., Demeter A., Papai N., Lenti K., Csermely P., Vellai T., Korcsmaros T., Varga M.: SignaFish: A Zebrafish-Specific Signaling Pathway Resource. Zebrafish, 2016, 13:541-544
  12. Csermely P., Korcsmaros T., Nussinov R.: Intracellular and intercellular signaling networks in cancer initiation, development and precision anti-cancer therapy: RAS acts as contextual signaling hub. Semin Cell Dev Biol, 2016, 58:55-59
  13. Danos K., Brauswetter D., Birtalan E., Pato A., Bencsik G., Krenacs T., Petak I., Tamas L.: The Potential Prognostic Value of Connexin 43 Expression in Head and Neck Squamous Cell Carcinomas. Appl Immunohistochem Mol Morphol, 2016, 24:476-481
  14. Dory M., Doleschall Z., Nagy S. K., Ambrus H., Meszaros T., Barnabas B., Doczi R.: Kinase-Associated Phosphoisoform Assay: a novel candidate-based method to detect specific kinase-substrate phosphorylation interactions in vivo. BMC Plant Biol, 2016, 16:204
  15. Dulk M., Kudlik G., Fekete A., Ernszt D., Kvell K., Pongracz J. E., Mero B. L., Szeder B., Radnai L., Geiszt M., Csecsy D. E., Kovacs T., Uher F., Lanyi A., Vas V., Buday L.: The scaffold protein Tks4 is required for the differentiation of mesenchymal stromal cells (MSCs) into adipogenic and osteogenic lineages. Sci Rep, 2016, 6:34280
  16. Elek Z., Denes R., Prokop S., Somogyi A., Yowanto H., Luo J., Souquet M., Guttman A., Ronai Z.: Multicapillary gel electrophoresis based analysis of genetic variants in the WFS1 gene. Electrophoresis, 2016, 37:2313-2321
  17. Forde N. J., Kanaan A. S., Widomska J., Padmanabhuni S. S., Nespoli E., Alexander J., Rodriguez Arranz J. I., Fan S., Houssari R., Nawaz M. S., Rizzo F., Pagliaroli L., Zilhao N. R., Aranyi T., Barta C., Boeckers T. M., Boomsma D. I., Buisman W. R., Buitelaar J. K., Cath D., Dietrich A., Driessen N., Drineas P., Dunlap M., Gerasch S., Glennon J., Hengerer B., van den Heuvel O. A., Jespersgaard C., Moller H. E., Muller-Vahl K. R., Openneer T. J., Poelmans G., Pouwels P. J., Scharf J. M., Stefansson H., Tumer Z., Veltman D. J., van der Werf Y. D., Hoekstra P. J., Ludolph A., Paschou P.: TS-EUROTRAIN: A European-Wide Investigation and Training Network on the Etiology and Pathophysiology of Gilles de la Tourette Syndrome. Front Neurosci, 2016, 10:384
  18. Garamvolgyi R., Dobos J., Sipos A., Boros S., Illyes E., Baska F., Kekesi L., Szabadkai I., Szantai-Kis C., Keri G., Orfi L.: Design and synthesis of new imidazo[1,2-a]pyridine and imidazo[1,2-a]pyrazine derivatives with antiproliferative activity against melanoma cells. Eur J Med Chem, 2016, 108:623-643
  19. Gellai R., Hodrea J., Lenart L., Hosszu A., Koszegi S., Balogh D., Ver A., Banki N. F., Fulop N., Molnar A., Wagner L., Vannay A., Szabo A. J., Fekete A.: Role of O-linked N-acetylglucosamine modification in diabetic nephropathy. Am J Physiol Renal Physiol, 2016, 311:F1172-F1181
  20. Gyurkovics M., Kotyuk E., Katonai E. R., Horvath E. Z., Vereczkei A., Szekely A.: Individual differences in flow proneness are linked to a dopamine D2 receptor gene variant. Conscious Cogn, 2016, 42:1-8
  21. Hathy E., Kalman S., Apati A., Nemoda Z., Rethelyi J. M.: [Modeling neurological and psychiatric disorders in vitro using induced pluripotent stem cells: highlighting findings in Alzheimer’s disease and schizophrenia]. Neuropsychopharmacol Hung, 2016, 18:188-198
  22. Holczer M., Banhegyi G., Kapuy O.: GADD34 Keeps the mTOR Pathway Inactivated in Endoplasmic Reticulum Stress Related Autophagy. PLoS One, 2016, 11:e0168359
  23. Keczan E., Keri G., Banhegyi G., Stiller I.: Effect of pulsed electromagnetic fields on endoplasmic reticulum stress. J Physiol Pharmacol, 2016, 67:769-775
  24. Kiss H. J., Takacs A. I., Kranitz K., Sandor G. L., Toth G., Gilanyi B., Nagy Z. Z.: One-Day Use of Preoperative Topical Nonsteroidal Anti-Inflammatory Drug Prevents Intraoperative Prostaglandin Level Elevation During Femtosecond Laser-Assisted Cataract Surgery. Curr Eye Res, 2016, 41:1064-1067
  25. Klionsky D. J.,..: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy, 2016, 12:1-222
  26. Kotyuk E., Nemeth N., Ronai Z., Demetrovics Z., Sasvari-Szekely M., Szekely A.: Association between smoking behaviour and genetic variants of glial cell line-derived neurotrophic factor. J Genet, 2016, 95:811-818
  27. Marczell I., Hrabak A., Nyiro G., Patocs A., Stark J., Dinya E., Kukor Z., Toth S., Tulassay Z. S., Racz K., Bekesi G.: 17-beta-estradiol Decreases Neutrophil Superoxide Production through Rac1. Exp Clin Endocrinol Diabetes, 2016, 124:588-592
  28. Modos D., Brooks J., Fazekas D., Ari E., Vellai T., Csermely P., Korcsmaros T., Lenti K.: Identification of critical paralog groups with indispensable roles in the regulation of signaling flow. Sci Rep, 2016, 6:38588
  29. Mozes P., Hauser P., Hortobagyi T., Benyo G., Petak I., Garami M., Cserhati A., Bartyik K., Bognar L., Nagy Z., Turanyi E., Hideghety K.: Evaluation of the good tumor response of embryonal tumor with abundant neuropil and true rosettes (ETANTR). J Neurooncol, 2016, 126:99-105
  30. Muranyi J., Gyulavari P., Varga A., Bokonyi G., Tanai H., Vantus T., Pap D., Ludanyi K., Mezo G., Keri G.: Synthesis, characterization and systematic comparison of FITC-labelled GnRH-I, -II and -III analogues on various tumour cells. J Pept Sci, 2016, 22:552-560
  31. Nemeth C. E., Marcolongo P., Gamberucci A., Fulceri R., Benedetti A., Zoppi N., Ritelli M., Chiarelli N., Colombi M., Willaert A., Callewaert B. L., Coucke P. J., Grof P., Nagy S. K., Meszaros T., Banhegyi G., Margittai E.: Glucose transporter type 10-lacking in arterial tortuosity syndrome-facilitates dehydroascorbic acid transport. FEBS Lett, 2016, 590:1630-1640
  32. Nussinov R., Tsai C. J., Jang H., Korcsmaros T., Csermely P.: Oncogenic KRAS signaling and YAP1/beta-catenin: Similar cell cycle control in tumor initiation. Semin Cell Dev Biol, 2016, 58:79-85
  33. Pagliaroli L., Veto B., Aranyi T., Barta C.: From Genetics to Epigenetics: New Perspectives in Tourette Syndrome Research. Front Neurosci, 2016, 10:277
  34. Simon-Szabo L., Kokas M., Greff Z., Boros S., Banhegyi P., Zsakai L., Szantai-Kis C., Vantus T., Mandl J., Banhegyi G., Valyi-Nagy I., Orfi L., Ullrich A., Csala M., Keri G.: Novel compounds reducing IRS-1 serine phosphorylation for treatment of diabetes. Bioorg Med Chem Lett, 2016, 26:424-428
  35. Somogyi A., Horvai G., Csala M., Toth B.: Analytical Approaches for the Quantitation of Redox-active Pyridine Dinucleotides in Biological Matrices. Period. Polytech.-Chem. Eng., 2016, 60:218-230
  36. Szekely A., Kotyuk E., Bircher J., Vereczkei A., Balota D. A., Sasvari-Szekely M., Ronai Z.: Association between Age and the 7 Repeat Allele of the Dopamine D4 Receptor Gene. PLoS One, 2016, 11:e0167753
  37. Zambo V., Toth M., Schlachter K., Szelenyi P., Sarnyai F., Lotz G., Csala M., Kereszturi E.: Cytosolic localization of NADH cytochrome b(5) oxidoreductase (Ncb5or). FEBS Lett, 2016, 590:661-671

2015

  1. Adam C., Fekete A., Bogel G., Nemeth Z., Tokesi N., Ovadi J., Liliom K., Pesti S., Geiszt M., Buday L.: Accumulation of the PX domain mutant Frank-ter Haar syndrome protein Tks4 in aggresomes. Cell communication and signaling : CCS, 2015, 13:33
  2. Alexeyenko A., Alkasalias T., Pavlova T., Szekely L., Kashuba V., Rundqvist H., Wiklund P., Egevad L., Csermely P., Korcsmaros T., Guven H., Klein G.: Confrontation of fibroblasts with cancer cells in vitro: gene network analysis of transcriptome changes and differential capacity to inhibit tumor growth. Journal of experimental & clinical cancer research : CR, 2015, 34:62
  3. Balogh P., Magyar M., Szabo A., Mullner N., Liko I., Patocs A., Kiss A. L.: The subcellular compartmentalization of TGFbeta-RII and the dynamics of endosomal formation during the signaling events: An in vivo study on rat mesothelial cells. European journal of cell biology, 2015, 94:204-213
  4. Balogh T., Lorincz T., Stiller I., Mandl J., Banhegyi G., Szarka A.: The Level of ALR is Regulated by the Quantity of Mitochondrial DNA. Pathology oncology research : POR, 2015,
  5. Banlaki Z., Elek Z., Nanasi T., Szekely A., Nemoda Z., Sasvari-Szekely M., Ronai Z.: Polymorphism in the serotonin receptor 2a (HTR2A) gene as possible predisposal factor for aggressive traits. PloS one, 2015, 10:e0117792
  6. Bertelsen B., Stefansson H., Riff Jensen L., Melchior L., Mol Debes N., Groth C., Skov L., Werge T., Karagiannidis I., Tarnok Z., Barta C., Nagy P., Farkas L., Brondum-Nielsen K., Rizzo R., Gulisano M., Rujescu D., Kiemeney L. A., Tosato S., Nawaz M. S., Ingason A., Unnsteinsdottir U., Steinberg S., Ludvigsson P., Stefansson K., Kuss A. W., Paschou P., Cath D., Hoekstra P. J., Muller-Vahl K., Stuhrmann M., Silahtaroglu A., Pfundt R., Tumer Z.: Association of AADAC Deletion and Gilles de la Tourette Syndrome in a Large European Cohort. Biological psychiatry, 2015,
  7. Csala M.: Entrance of Electrons to Acyl-CoA Desaturation. Austin Journal of Molecular and Cellular Biology, 2015, 2:1005
  8. Csala M., Kardon T., Legeza B., Lizak B., Mandl J., Margittai E., Puskas F., Szaraz P., Szelenyi P., Banhegyi G.: On the role of 4-hydroxynonenal in health and disease. Biochimica et biophysica acta, 2015, 1852:826-838
  9. Csermely P., Hodsagi J., Korcsmaros T., Modos D., Perez-Lopez A. R., Szalay K., Veres D. V., Lenti K., Wu L. Y., Zhang X. S.: Cancer stem cells display extremely large evolvability: alternating plastic and rigid networks as a potential Mechanism: network models, novel therapeutic target strategies, and the contributions of hypoxia, inflammation and cellular senescence. Seminars in cancer biology, 2015, 30:42-51
  10. Elek Z., Nemeth N., Nagy G., Nemeth H., Somogyi A., Hosszufalusi N., Sasvari-Szekely M., Ronai Z.: Micro-RNA Binding Site Polymorphisms in the WFS1 Gene Are Risk Factors of Diabetes Mellitus. PloS one, 2015, 10:e0139519
  11. Garbett K. A., Vereczkei A., Kalman S., Brown J. A., Taylor W. D., Faludi G., Korade Z., Shelton R. C., Mirnics K.: Coordinated messenger RNA/microRNA changes in fibroblasts of patients with major depression. Biological psychiatry, 2015, 77:256-265
  12. Gyurko M. D., Csermely P., Soti C., Stetak A.: Distinct roles of the RasGAP family proteins in C. elegans associative learning and memory. Scientific reports, 2015, 5:15084
  13. Gyurko M. D., Stetak A., Soti C., Csermely P.: Multitarget network strategies to influence memory and forgetting: the Ras/MAPK pathway as a novel option. Mini reviews in medicinal chemistry, 2015, 15:696-704
  14. Herrero A., Pinto A., Colon-Bolea P., Casar B., Jones M., Agudo-Ibanez L., Vidal R., Tenbaum S. P., Nuciforo P., Valdizan E. M., Horvath Z., Orfi L., Pineda-Lucena A., Bony E., Keri G., Rivas G., Pazos A., Gozalbes R., Palmer H. G., Hurlstone A., Crespo P.: Small Molecule Inhibition of ERK Dimerization Prevents Tumorigenesis by RAS-ERK Pathway Oncogenes. Cancer cell, 2015, 28:170-182
  15. Holczer M., Marton M., Kurucz A., Banhegyi G., Kapuy O.: A Comprehensive Systems Biological Study of Autophagy-Apoptosis Crosstalk during Endoplasmic Reticulum Stress. BioMed research international, 2015, 2015:319589
  16. Jaczo Z., Pal E., Denes R., Somogyi A., Sasvari-Szekely M., Guttman A., Ronai Z.: Rapid analysis of colipase gene variants by multicapillary electrophoresis. Electrophoresis, 2015, 36:1237-1243
  17. Kohoutova L., Kourova H., Nagy S. K., Volc J., Halada P., Meszaros T., Meskiene I., Bogre L., Binarova P.: The Arabidopsis mitogen-activated protein kinase 6 is associated with gamma-tubulin on microtubules, phosphorylates EB1c and maintains spindle orientation under nitrosative stress. The New phytologist, 2015, 207:1061-1074
  18. Kovacs I. A., Mizsei R., Csermely P.: A unified data representation theory for network visualization, ordering and coarse-graining. Scientific reports, 2015, 5:13786
  19. Lavoz C., Alique M., Rodrigues-Diez R., Pato J., Keri G., Mezzano S., Egido J., Ruiz-Ortega M.: Gremlin regulates renal inflammation via the vascular endothelial growth factor receptor 2 pathway. The Journal of pathology, 2015, 236:407-420
  20. Lorincz T., Jemnitz K., Kardon T., Mandl J., Szarka A.: Ferroptosis is Involved in Acetaminophen Induced Cell Death. Pathology oncology research : POR, 2015, 21:1115-1121
  21. Marcsa B., Denes R., Voros K., Racz G., Sasvari-Szekely M., Ronai Z., Toro K., Keszler G.: A Common Polymorphism of the Human Cardiac Sodium Channel Alpha Subunit (SCN5A) Gene Is Associated with Sudden Cardiac Death in Chronic Ischemic Heart Disease. PloS one, 2015, 10:e0132137
  22. Margittai E., Enyedi B., Csala M., Geiszt M., Banhegyi G.: Composition of the redox environment of the endoplasmic reticulum and sources of hydrogen peroxide. Free radical biology & medicine, 2015, 83:331-340
  23. Micsik T., Lorincz A., Mersich T., Baranyai Z., Besznyak I., Jr., Dede K., Zarand A., Jakab F., Szollosi L. K., Keri G., Schwab R., Petak I.: Decreased functional activity of multidrug resistance protein in primary colorectal cancer. Diagnostic pathology, 2015, 10:26
  24. Nagy S. K., Darula Z., Kallai B. M., Bogre L., Banhegyi G., Medzihradszky K. F., Horvath G. V., Meszaros T.: Activation of AtMPK9 through autophosphorylation that makes it independent of the canonical MAPK cascades. The Biochemical journal, 2015, 467:167-175
  25. Nemoda Z., Massart R., Suderman M., Hallett M., Li T., Coote M., Cody N., Sun Z. S., Soares C. N., Turecki G., Steiner M., Szyf M.: Maternal depression is associated with DNA methylation changes in cord blood T lymphocytes and adult hippocampi. Translational psychiatry, 2015, 5:e545
  26. Perez-Lopez A. R., Szalay K. Z., Turei D., Modos D., Lenti K., Korcsmaros T., Csermely P.: Targets of drugs are generally, and targets of drugs having side effects are specifically good spreaders of human interactome perturbations. Scientific reports, 2015, 5:10182
  27. Sipos A., Pato J., Szekely R., Hartkoorn R. C., Kekesi L., Orfi L., Szantai-Kis C., Mikusova K., Svetlikova Z., Kordulakova J., Nagaraja V., Godbole A. A., Bush N., Collin F., Maxwell A., Cole S. T., Keri G.: Lead selection and characterization of antitubercular compounds using the Nested Chemical Library. Tuberculosis, 2015, 95 Suppl 1:S200-206
  28. Skutle A., Bu E. T. H., Jellestad F. K., van Emmerik-van Oortmerssen K., Dom G., Verspreet S., Carpentier P. J., Ramos-Quiroga J. A., Franck J., Konstenius M., Kaye S., Demetrovics Z., Barta C., Fatséas M., Auriacombe M., Johnson B., Faraone S. V., Levin F. R., Allsop S., Carruthers S., Schoevers R. A., Koeter M. W. J., van den Brink W., Moggi F., Møller M., van de Glind G.: Early developmental, temperamental and educational problems in ‘substance use disorder’ patients with and without ADHD. Does ADHD make a difference? Addictive Behaviors Reports, 2015, 2:13-18
  29. Turei D., Foldvari-Nagy L., Fazekas D., Modos D., Kubisch J., Kadlecsik T., Demeter A., Lenti K., Csermely P., Vellai T., Korcsmaros T.: Autophagy Regulatory Network – a systems-level bioinformatics resource for studying the mechanism and regulation of autophagy. Autophagy, 2015, 11:155-165
  30. van den Kieboom C. H., van der Beek S. L., Meszaros T., Gyurcsanyi R. E., Ferwerda G., de Jonge M. I.: Aptasensors for viral diagnostics. Trac-Trend Anal Chem, 2015, 74:58-67
  31. Varga A., Gyulavari P., Greff Z., Futosi K., Nemeth T., Simon-Szabo L., Kerekes K., Szantai-Kis C., Brauswetter D., Kokas M., Borbely G., Erdei A., Mocsai A., Keri G., Vantus T.: Targeting vascular endothelial growth factor receptor 2 and protein kinase D1 related pathways by a multiple kinase inhibitor in angiogenesis and inflammation related processes in vitro. PloS one, 2015, 10:e0124234
  32. Veres D. V., Gyurko D. M., Thaler B., Szalay K. Z., Fazekas D., Korcsmaros T., Csermely P.: ComPPI: a cellular compartment-specific database for protein-protein interaction network analysis. Nucleic acids research, 2015, 43:D485-493
  33. Wapp M., van de Glind G., van Emmerik-van Oortmerssen K., Dom G., Verspreet S., Carpentier P. J., Ramos-Quiroga J. A., Skutle A., Bu E. T., Franck J., Konstenius M., Kaye S., Demetrovics Z., Barta C., Fatseas M., Auriacombe M., Johnson B., Faraone S. V., Levin F. R., Allsop S., Carruthers S., Schoevers R. A., Koeter M. W., van den Brink W., Moggi F., Group I. R.: Risk Factors for Borderline Personality Disorder in Treatment Seeking Patients with a Substance Use Disorder: An International Multicenter Study. European addiction research, 2015, 21:188-194
  34. Zilhao N. R., Padmanabhuni S. S., Pagliaroli L., Barta C., Consortium B., Smit D. J., Cath D., Nivard M. G., Baselmans B. M., van Dongen J., Paschou P., Boomsma D. I.: Epigenome-Wide Association Study of Tic Disorders. Twin research and human genetics : the official journal of the International Society for Twin Studies, 2015, 18:699-709

2014

  1. Banhegyi G., Benedetti A., Margittai E., Marcolongo P., Fulceri R., Nemeth C. E., Szarka A.: Subcellular compartmentation of ascorbate and its variation in disease states. Biochim Biophys Acta, 2014, 1843:1909-1916
  2. Barman S. A., Chen F., Su Y., Dimitropoulou C., Wang Y., Catravas J. D., Han W., Orfi L., Szantai-Kis C., Keri G., Szabadkai I., Barabutis N., Rafikova O., Rafikov R., Black S. M., Jonigk D., Giannis A., Asmis R., Stepp D. W., Ramesh G., Fulton D. J.: NADPH oxidase 4 is expressed in pulmonary artery adventitia and contributes to hypertensive vascular remodeling. Arterioscler Thromb Vasc Biol, 2014, 34:1704-1715
  3. Baska F., Szabadkai I., Sipos A., Breza N., Szantai-Kis C., Kekesi L., Garamvolgyi R., Nemes Z., Baska F., Neumann L., Torka R., Ullrich A., Keri G., Orfi L.: Pharmacophore and binding analysis of known and novel B-RAF kinase inhibitors. Curr Med Chem, 2014, 21:1938-1955
  4. Foldvari-Nagy L., Ari E., Csermely P., Korcsmaros T., Vellai T.: Starvation-response may not involve Atg1-dependent autophagy induction in non-unikont parasites. Sci Rep, 2014, 4:5829
  5. Gyollai A., Griffiths M. D., Barta C., Vereczkei A., Urban R., Kun B., Kokonyei G., Szekely A., Sasvari-Szekely M., Blum K., Demetrovics Z.: The genetics of problem and pathological gambling: a systematic review. Curr Pharm Des, 2014, 20:3993-3999
  6. Gyorffy B., Bottai G., Lehmann-Che J., Keri G., Orfi L., Iwamoto T., Desmedt C., Bianchini G., Turner N. C., de The H., Andre F., Sotiriou C., Hortobagyi G. N., Di Leo A., Pusztai L., Santarpia L.: TP53 mutation-correlated genes predict the risk of tumor relapse and identify MPS1 as a potential therapeutic kinase in TP53-mutated breast cancers. Mol Oncol, 2014, 8:508-519
  7. Gyurko D. M., Soti C., Stetak A., Csermely P.: System level mechanisms of adaptation, learning, memory formation and evolvability: the role of chaperone and other networks. Curr Protein Pept Sci, 2014, 15:171-188
  8. Kalman S., Garbett K. A., Vereczkei A., Shelton R. C., Korade Z., Mirnics K.: Metabolic stress-induced microRNA and mRNA expression profiles of human fibroblasts. Exp Cell Res, 2014, 320:343-353
  9. Kapuy O., Lizák B., Stiller I., Bánhegyi G.: A Systems Biological Perspective of Cellular Stress-Directed Programmed Cell Death. Computational Molecular Bioscience, 2014, 4:28-34
  10. Kapuy O., Vinod P. K., Banhegyi G.: mTOR inhibition increases cell viability via autophagy induction during endoplasmic reticulum stress – An experimental and modeling study. FEBS Open Bio, 2014, 4:704-713
  11. Kaucsar T., Bodor C., Godo M., Szalay C., Revesz C., Nemeth Z., Mozes M., Szenasi G., Rosivall L., Soti C., Hamar P.: LPS-induced delayed preconditioning is mediated by Hsp90 and involves the heat shock response in mouse kidney. PLoS One, 2014, 9:e92004
  12. Keszler G., Kruk E., Kenezloi E., Tarnok Z., Sasvari-Szekely M., Nemoda Z.: Association of the tumor necrosis factor -308 A/G promoter polymorphism with Tourette syndrome. Int J Immunogenet, 2014, 41:493-498
  13. Kis A., Bence M., Lakatos G., Pergel E., Turcsan B., Pluijmakers J., Vas J., Elek Z., Bruder I., Foldi L., Sasvari-Szekely M., Miklosi A., Ronai Z., Kubinyi E.: Oxytocin receptor gene polymorphisms are associated with human directed social behavior in dogs (Canis familiaris). PLoS One, 2014, 9:e83993
  14. Kotyuk E., Sasvari-Szekely M., Szekely A.: [Neurocognitive endophenotypes in psychiatric genetics]. Neuropsychopharmacol Hung, 2014, 16:85-90
  15. Mavromatidis V., Varga Z., Waczek F., Orfi Z., Orfi L., Keri G., Mosialos G.: Identification of protein kinase inhibitors with a selective negative effect on the viability of Epstein-Barr virus infected B cell lines. PLoS One, 2014, 9:e95688
  16. McKeague M., Velu R., Hill K., Bardoczy V., Meszaros T., DeRosa M. C.: Selection and characterization of a novel DNA aptamer for label-free fluorescence biosensing of ochratoxin A. Toxins (Basel), 2014, 6:2435-2452
  17. Nemeth G., Greff Z., Sipos A., Varga Z., Szekely R., Sebestyen M., Jaszay Z., Beni S., Nemes Z., Pirat J. L., Volle J. N., Virieux D., Gyuris A., Kelemenics K., Ay E., Minarovits J., Szathmary S., Keri G., Orfi L.: Synthesis and evaluation of phosphorus containing, specific CDK9/CycT1 inhibitors. J Med Chem, 2014, 57:3939-3965
  18. Nemeth N., Kerekgyarto M., Sasvari-Szekely M., Ronai Z., Guttman A.: Rapid identification of human SNAP-25 transcript variants by a miniaturized capillary electrophoresis system. Electrophoresis, 2014, 35:379-384
  19. Otero J. H., Lizak B., Feige M. J., Hendershot L. M.: Dissection of structural and functional requirements that underlie the interaction of ERdj3 protein with substrates in the endoplasmic reticulum. J Biol Chem, 2014, 289:27504-27512
  20. Pallagi P., Balla Z., Singh A. K., Dosa S., Ivanyi B., Kukor Z., Toth A., Riederer B., Liu Y., Engelhardt R., Jarmay K., Szabo A., Janovszky A., Perides G., Venglovecz V., Maleth J., Wittmann T., Takacs T., Gray M. A., Gacser A., Hegyi P., Seidler U., Rakonczay Z., Jr.: The role of pancreatic ductal secretion in protection against acute pancreatitis in mice*. Crit Care Med, 2014, 42:e177-188
  21. Paschou P., Yu D., Gerber G., Evans P., Tsetsos F., Davis L. K., Karagiannidis I., Chaponis J., Gamazon E., Mueller-Vahl K., Stuhrmann M., Schloegelhofer M., Stamenkovic M., Hebebrand J., Noethen M., Nagy P., Barta C., Tarnok Z., Rizzo R., Depienne C., Worbe Y., Hartmann A., Cath D. C., Budman C. L., Sandor P., Barr C., Wolanczyk T., Singer H., Chou I. C., Grados M., Posthuma D., Rouleau G. A., Aschauer H., Freimer N. B., Pauls D. L., Cox N. J., Mathews C. A., Scharf J. M.: Genetic association signal near NTN4 in Tourette syndrome. Ann Neurol, 2014, 76:310-315
  22. Penzes K., Baumann C., Szabadkai I., Orfi L., Keri G., Ullrich A., Torka R.: Combined inhibition of AXL, Lyn and p130Cas kinases block migration of triple negative breast cancer cells. Cancer Biol Ther, 2014, 15:1571-1582
  23. Ronai Z., Kovacs-Nagy R., Szantai E., Elek Z., Sasvari-Szekely M., Faludi G., Benkovits J., Rethelyi J. M., Szekely A.: Glycogen synthase kinase 3 beta gene structural variants as possible risk factors of bipolar depression. Am J Med Genet B Neuropsychiatr Genet, 2014, 165B:217-222
  24. Rybniker J., Chen J. M., Sala C., Hartkoorn R. C., Vocat A., Benjak A., Boy-Rottger S., Zhang M., Szekely R., Greff Z., Orfi L., Szabadkai I., Pato J., Keri G., Cole S. T.: Anticytolytic screen identifies inhibitors of mycobacterial virulence protein secretion. Cell Host Microbe, 2014, 16:538-548
  25. Schwab R., Petak I., Kollar M., Pinter F., Varkondi E., Kohanka A., Barti-Juhasz H., Schonleber J., Brauswetter D., Kopper L., Urban L.: Major partial response to crizotinib, a dual MET/ALK inhibitor, in a squamous cell lung (SCC) carcinoma patient with de novo c-MET amplification in the absence of ALK rearrangement. Lung Cancer, 2014, 83:109-111
  26. Simon-Szabo L., Kokas M., Mandl J., Keri G., Csala M.: Metformin attenuates palmitate-induced endoplasmic reticulum stress, serine phosphorylation of IRS-1 and apoptosis in rat insulinoma cells. PLoS One, 2014, 9:e97868
  27. Stiller I., Lizak B., Banhegyi G.: Physiological functions of presenilins; beyond gamma-secretase. Curr Pharm Biotechnol, 2014, 15:1019-1025
  28. Szalay K. Z., Nussinov R., Csermely P.: Attractor Structures of Signaling Networks: Consequences of Different Conformational Barcode Dynamics and Their Relations to Network-Based Drug Design. Molecular Informatics, 2014, 33:463-468
  29. Szarka A., Banhegyi G., Sumegi B.: [Mitochondria, oxidative stress and aging]. Orv Hetil, 2014, 155:447-452
  30. Szeitner Z., Andras J., Gyurcsanyi R. E., Meszaros T.: Is less more? Lessons from aptamer selection strategies. J Pharm Biomed Anal, 2014, 101:58-65
  31. Szeitner Z., Lautner G., Nagy S. K., Gyurcsanyi R. E., Meszaros T.: A rational approach for generating cardiac troponin I selective Spiegelmers. Chem Commun (Camb), 2014, 50:6801-6804
  32. Szokol B., Gyulavari P., Kurko I., Baska F., Szantai-Kis C., Greff Z., Orfi Z., Petak I., Penzes K., Torka R., Ullrich A., Orfi L., Vantus T., Keri G.: Discovery and Biological Evaluation of Novel Dual EGFR/c-Met Inhibitors. ACS Med Chem Lett, 2014, 5:298-303
  33. Torka R., Penzes K., Gusenbauer S., Baumann C., Szabadkai I., Orfi L., Keri G., Ullrich A.: Activation of HER3 interferes with antitumor effects of Axl receptor tyrosine kinase inhibitors: suggestion of combination therapy. Neoplasia, 2014, 16:301-318
  34. van de Glind G., Konstenius M., Koeter M. W., van Emmerik-van Oortmerssen K., Carpentier P. J., Kaye S., Degenhardt L., Skutle A., Franck J., Bu E. T., Moggi F., Dom G., Verspreet S., Demetrovics Z., Kapitany-Foveny M., Fatseas M., Auriacombe M., Schillinger A., Moller M., Johnson B., Faraone S. V., Ramos-Quiroga J. A., Casas M., Allsop S., Carruthers S., Schoevers R. A., Wallhed S., Barta C., Alleman P., Levin F. R., van den Brink W., Group I. R.: Variability in the prevalence of adult ADHD in treatment seeking substance use disorder patients: results from an international multi-center study exploring DSM-IV and DSM-5 criteria. Drug Alcohol Depend, 2014, 134:158-166
  35. van Emmerik-van Oortmerssen K., van de Glind G., Koeter M. W., Allsop S., Auriacombe M., Barta C., Bu E. T., Burren Y., Carpentier P. J., Carruthers S., Casas M., Demetrovics Z., Dom G., Faraone S. V., Fatseas M., Franck J., Johnson B., Kapitany-Foveny M., Kaye S., Konstenius M., Levin F. R., Moggi F., Moller M., Ramos-Quiroga J. A., Schillinger A., Skutle A., Verspreet S., group I. r., van den Brink W., Schoevers R. A.: Psychiatric comorbidity in treatment-seeking substance use disorder patients with and without attention deficit hyperactivity disorder: results of the IASP study. Addiction, 2014, 109:262-272

2013

  1. Bánki N. F., Kőszegi S., Wagner L., Lénárt L., Varga D., Gellai R., Hodrea J., Vér Á., Szabó J. A., Tulassay T., Fekete A.: Új terápiás támpontok a diabéteszes nephropathia kezelésében: a renin-angiotenzin-aldoszteron-rendszer és a Na/K ATP-áz szerepe. Gyermekgyógyászat, 2013, 64:70-73
  2. Banlaki Z., Szabo J. A., Szilagyi A., Patocs A., Prohaszka Z., Fust G., Doleschall M.: Intraspecific evolution of human RCCX copy number variation traced by haplotypes of the CYP21A2 gene. Genome Biol Evol, 2013, 5:98-112
  3. Baska F., Szekely E. R., Szantai-Kis C., Banhegyi P., Hegymegi-Barakonyi B., Nemeth G., Breza N., Zsakai L., Greff Z., Pato J., Keri G., Orfi L.: [Development and study of structure-activity relationship of drugs against Mycobacterium tuberculosis]. Acta Pharm Hung, 2013, 83:88-95
  4. Bozoky B., Savchenko A., Csermely P., Korcsmaros T., Dul Z., Ponten F., Szekely L., Klein G.: Novel signatures of cancer-associated fibroblasts. Int J Cancer, 2013, 133:286-293
  5. Crul T., Toth N., Piotto S., Literati-Nagy P., Tory K., Haldimann P., Kalmar B., Greensmith L., Torok Z., Balogh G., Gombos I., Campana F., Concilio S., Gallyas F., Nagy G., Berente Z., Gungor B., Peter M., Glatz A., Hunya A., Literati-Nagy Z., Vigh L., Jr., Hoogstra-Berends F., Heeres A., Kuipers I., Loen L., Seerden J. P., Zhang D., Meijering R. A., Henning R. H., Brundel B. J., Kampinga H. H., Koranyi L., Szilvassy Z., Mandl J., Sumegi B., Febbraio M. A., Horvath I., Hooper P. L., Vigh L.: Hydroximic acid derivatives: pleiotropic HSP co-inducers restoring homeostasis and robustness. Curr Pharm Des, 2013, 19:309-346
  6. Csermely P., Korcsmaros T.: Cancer-related networks: a help to understand, predict and change malignant transformation. Semin Cancer Biol, 2013, 23:209-212
  7. Csermely P., Korcsmaros T., Kiss H. J., London G., Nussinov R.: Structure and dynamics of molecular networks: a novel paradigm of drug discovery: a comprehensive review. Pharmacol Ther, 2013, 138:333-408
  8. Csermely P., Nussinov R., Szilagyi A.: From allosteric drugs to allo-network drugs: state of the art and trends of design, synthesis and computational methods. Curr Top Med Chem, 2013, 13:2-4
  9. Fazekas D., Koltai M., Turei D., Modos D., Palfy M., Dul Z., Zsakai L., Szalay-Beko M., Lenti K., Farkas I. J., Vellai T., Csermely P., Korcsmaros T.: SignaLink 2 – a signaling pathway resource with multi-layered regulatory networks. BMC Syst Biol, 2013, 7:7
  10. Fekete A., G B. G., Pesti S., Peterfi Z., Geiszt M., Buday L.: EGF regulates tyrosine phosphorylation and membrane-translocation of the scaffold protein Tks5. J Mol Signal, 2013, 8:8
  11. Gyurko D. M., Veres D. V., Modos D., Lenti K., Korcsmaros T., Csermely P.: Adaptation and learning of molecular networks as a description of cancer development at the systems-level: potential use in anti-cancer therapies. Semin Cancer Biol, 2013, 23:262-269
  12. Haas D. A., Bala K., Busche G., Weidner-Glunde M., Santag S., Kati S., Gramolelli S., Damas M., Dittrich-Breiholz O., Kracht M., Ruckert J., Varga Z., Keri G., Schulz T. F.: The inflammatory kinase MAP4K4 promotes reactivation of Kaposi’s sarcoma herpesvirus and enhances the invasiveness of infected endothelial cells. PLoS Pathog, 2013, 9:e1003737
  13. Halmai Z., Dome P., Dobos J., Gonda X., Szekely A., Sasvari-Szekely M., Faludi G., Lazary J.: Peripheral vascular endothelial growth factor level is associated with antidepressant treatment response: results of a preliminary study. J Affect Disord, 2013, 144:269-273
  14. Halmai Z., Dome P., Vereczkei A., Abdul-Rahman O., Szekely A., Gonda X., Faludi G., Sasvari-Szekely M., Nemoda Z.: Associations between depression severity and purinergic receptor P2RX7 gene polymorphisms. J Affect Disord, 2013, 150:104-109
  15. Hegedus T., Gyimesi G., Gaspar M. E., Szalay K. Z., Gangal R., Csermely P.: Potential application of network descriptions for understanding conformational changes and protonation states of ABC transporters. Curr Pharm Des, 2013, 19:4155-4172
  16. Hegymegi-Barakonyi B., Orfi L., Keri G., Kovesdi I.: [Application of Kohonen Self-Organizing Feature Maps in QSAR of human ADMET and kinase data sets]. Acta Pharm Hung, 2013, 83:143-148
  17. Ho H. K., Nemeth G., Ng Y. R., Pang E., Szantai-Kis C., Zsakai L., Breza N., Greff Z., Horvath Z., Pato J., Szabadkai I., Szokol B., Baska F., Orfi L., Ullrich A., Keri G., Chua B. T.: Developing FGFR4 inhibitors as potential anti-cancer agents via in silico design, supported by in vitro and cell-based testing. Curr Med Chem, 2013, 20:1203-1217
  18. Hodrea J., Lénárt L., Gellai R., Kőszegi S., Wagner L., Bánki N. F., Vér Á., Vannay Á., Tulassay T., Fekete A.: A diabeteshez társuló depresszió patomechanizmusa. Magyar Belorvosi Archivum, 2013, 66:198-203
  19. Kalman F. S., Lizak B., Nagy S. K., Meszaros T., Zambo V., Mandl J., Csala M., Kereszturi E.: Natural mutations lead to enhanced proteasomal degradation of human Ncb5or, a novel flavoheme reductase. Biochimie, 2013, 95:1403-1410
  20. Kapuy O., Banhegyi G.: Depletion of Luminal Pyridine Nucleotides in the Endoplasmic Reticulum Activates Autophagy with the Involvement of mTOR Pathway. Biomed Res Int, 2013, 2013:942431
  21. Kapuy O., Vinod P. K., Mandl J., Banhegyi G.: A cellular stress-directed bistable switch controls the crosstalk between autophagy and apoptosis. Mol Biosyst, 2013, 9:296-306
  22. Kekesi L., Sipos A., Nemeth G., Pato J., Breza N., Baska F., Orfi L., Keri G.: Synthesis and biological evaluation of novel pyrido[2,3-b]pyrazines inhibiting both erlotinib-sensitive and erlotinib-resistant cell lines. Bioorg Med Chem Lett, 2013, 23:6152-6155
  23. Kerekgyarto M., Nemeth N., Kerekes T., Ronai Z., Guttman A.: Ultrafast haplotyping of putative microRNA-binding sites in the WFS1 gene by multiplex polymerase chain reaction and capillary gel electrophoresis. J Chromatogr A, 2013, 1286:229-234
  24. Korcsmaros T., Dunai Z. A., Vellai T., Csermely P.: Teaching the bioinformatics of signaling networks: an integrated approach to facilitate multi-disciplinary learning. Brief Bioinform, 2013, 14:618-632
  25. Kotyuk E., Keszler G., Nemeth N., Ronai Z., Sasvari-Szekely M., Szekely A.: Glial Cell Line-Derived Neurotrophic Factor (GDNF) as a Novel Candidate Gene of Anxiety. PLoS One, 2013, 8:e80613
  26. Kotyuk E., Nemeth N., Halmai Z., Faludi G., Sasvari-Szekely M., Szekely A.: [Association between mood characteristics and polymorphisms of glial cell line-derived neurotrophic factor (GNDF) in patients with depression]. Neuropsychopharmacol Hung, 2013, 15:63-72
  27. Kovacs-Nagy R., Elek Z., Szekely A., Nanasi T., Sasvari-Szekely M., Ronai Z.: Association of aggression with a novel microRNA binding site polymorphism in the wolframin gene. Am J Med Genet B Neuropsychiatr Genet, 2013, 162B:404-412
  28. Kubisch J., Turei D., Foldvari-Nagy L., Dunai Z. A., Zsakai L., Varga M., Vellai T., Csermely P., Korcsmaros T.: Complex regulation of autophagy in cancer – integrated approaches to discover the networks that hold a double-edged sword. Semin Cancer Biol, 2013, 23:252-261
  29. Literati-Nagy Z., Tory K., Literati-Nagy B., Bajza A., Vigh L., Jr., Vigh L., Mandl J., Szilvassy Z.: Synergic insulin sensitizing effect of rimonabant and BGP-15 in Zucker-obese rats. Pathol Oncol Res, 2013, 19:571-575
  30. M C.: A túltáplált sejttől a cukorbetegségig: Új terápiás célpontok. Élet és Tudomány, 2013, 68:243-245
  31. Mandl J., Meszaros T., Banhegyi G., Csala M.: Minireview: endoplasmic reticulum stress: control in protein, lipid, and signal homeostasis. Mol Endocrinol, 2013, 27:384-393
  32. Marcolongo P., Fulceri R., Gamberucci A., Czegle I., Banhegyi G., Benedetti A.: Multiple roles of glucose-6-phosphatases in pathophysiology: state of the art and future trends. Biochim Biophys Acta, 2013, 1830:2608-2618
  33. Nemeth N., Kerekgyarto M., Sasvari-Szekely M., Ronai Z., Guttman A.: Rapid identification of human SNAP-25 transcript variants by a miniaturized capillary electrophoresis system. Electrophoresis, 2013,
  34. Nemeth N., Kovacs-Nagy R., Szekely A., Sasvari-Szekely M., Ronai Z.: Association of Impulsivity and Polymorphic MicroRNA-641 Target Sites in the SNAP-25 Gene. PLoS One, 2013, 8:e84207
  35. Nguyen M. T., Csermely P., Soti C.: Hsp90 chaperones PPARgamma and regulates differentiation and survival of 3T3-L1 adipocytes. Cell Death Differ, 2013, 20:1654-1663
  36. Nussinov R., Ma B., Tsai C. J., Csermely P.: Allosteric conformational barcodes direct signaling in the cell. Structure, 2013, 21:1509-1521
  37. P C.: The appearance and promotion of creativity by various levels of interdependent networks. Talent Development and Excellence, 2013, 5:115-123
  38. P C.: The Past, Present and Future of Cybernetics and Systems Research. SYSTEMA: CONNECTING MATTER, LIFE, CULTURE AND TECHNOLOGY, 2013, 1:4-13
  39. Rayego-Mateos S., Morgado-Pascual J. L., Sanz A. B., Ramos A. M., Eguchi S., Batlle D., Pato J., Keri G., Egido J., Ortiz A., Ruiz-Ortega M.: TWEAK transactivation of the epidermal growth factor receptor mediates renal inflammation. J Pathol, 2013, 231:480-494
  40. Rayego-Mateos S., Rodrigues-Diez R., Morgado-Pascual J. L., Rodrigues Diez R. R., Mas S., Lavoz C., Alique M., Pato J., Keri G., Ortiz A., Egido J., Ruiz-Ortega M.: Connective tissue growth factor is a new ligand of epidermal growth factor receptor. J Mol Cell Biol, 2013, 5:323-335
  41. Revesz K., Toth B., Staines A. G., Coughtrie M. W., Mandl J., Csala M.: Luminal accumulation of newly synthesized morphine-3-glucuronide in rat liver microsomal vesicles. Biofactors, 2013, 39:271-278
  42. Simko G. I., Csermely P.: Nodes having a major influence to break cooperation define a novel centrality measure: game centrality. PLoS One, 2013, 8:e67159
  43. Szalay K. Z., Csermely P.: Perturbation centrality and turbine: a novel centrality measure obtained using a versatile network dynamics tool. PLoS One, 2013, 8:e78059
  44. Szaraz P., Banhegyi G., Marcolongo P., Benedetti A.: Transient knockdown of presenilin-1 provokes endoplasmic reticulum stress related formation of autophagosomes in HepG2 cells. Arch Biochem Biophys, 2013, 538:57-63
  45. Szarka A., Banhegyi G., Asard H.: The inter-relationship of ascorbate transport, metabolism and mitochondrial, plastidic respiration. Antioxid Redox Signal, 2013, 19:1036-1044
  46. Szelenyi P., Revesz K., Konta L., Tutto A., Mandl J., Kereszturi E., Csala M.: Inhibition of microsomal cortisol production by (-)-epigallocatechin-3-gallate through a redox shift in the endoplasmic reticulum–a potential new target for treating obesity-related diseases. Biofactors, 2013, 39:534-541
  47. Szilagyi A., Nussinov R., Csermely P.: Allo-network drugs: extension of the allosteric drug concept to protein- protein interaction and signaling networks. Curr Top Med Chem, 2013, 13:64-77
  48. Szokol B., Gyulavari P., Baska F., Ibolya K., Greff Z., Szantai K. C., Zoltan O., Petak I., Axel U., Vantus T., Keri G., Orfi L.: [Development and biochemical characterization of EGFR/c-Met dual inhibitors]. Acta Pharm Hung, 2013, 83:121-133
  49. Turei D., Papp D., Fazekas D., Foldvari-Nagy L., Modos D., Lenti K., Csermely P., Korcsmaros T.: NRF2-ome: an integrated web resource to discover protein interaction and regulatory networks of NRF2. Oxid Med Cell Longev, 2013, 2013:737591
  50. Vereczkei A., Demetrovics Z., Szekely A., Sarkozy P., Antal P., Szilagyi A., Sasvari-Szekely M., Barta C.: Multivariate analysis of dopaminergic gene variants as risk factors of heroin dependence. PLoS One, 2013, 8:e66592
  51. Wan M., Hejjas K., Ronai Z., Elek Z., Sasvari-Szekely M., Champagne F. A., Miklosi A., Kubinyi E.: DRD4 and TH gene polymorphisms are associated with activity, impulsivity and inattention in Siberian Husky dogs. Anim Genet, 2013, 44:717-727
  52. Zambo V., Simon-Szabo L., Szelenyi P., Kereszturi E., Banhegyi G., Csala M.: Lipotoxicity in the liver. World J Hepatol, 2013, 5:550-557
  53. Zsakai L., Nemeth G., Szantai-Kis C., Greff Z., Horvath Z., Szokol B., Baska F., Boon T. C., Orfi L., Keri G.: [Developing FGFR inhibitors as potential anti-cancer agents]. Acta Pharm Hung, 2013, 83:47-56

2012

  1. Abdul-Rahman O., Sasvari-Szekely M., Ver A., Rosta K., Szasz B. K., Kereszturi E., Keszler G.: Altered gene expression profiles in the hippocampus and prefrontal cortex of type 2 diabetic rats. BMC genomics, 2012, 13:81
  2. Agoston V., Csermely P., Pongor S.: Multiple weak hits confuse complex systems: A transcriptional regulatory network as an example. Physical Review E – Statistical, Nonlinear, and Soft Matter Physics, 2005, 71:
  3. Anelli T., Bergamelli L., Margittai E., Rimessi A., Fagioli C., Malgaroli A., Pinton P., Ripamonti M., Rizzuto R., Sitia R.: Ero1alpha regulates Ca(2+) fluxes at the endoplasmic reticulum-mitochondria interface (MAM). Antioxidants & redox signaling, 2012, 16:1077-1087
  4. Arslan M. A., Chikina M., Csermely P., Soti C.: Misfolded proteins inhibit proliferation and promote stress-induced death in SV40-transformed mammalian cells. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2012, 26:766-777
  5. Banhegyi G., Margittai E., Szarka A., Mandl J., Csala M.: Crosstalk and barriers between the electron carriers of the endoplasmic reticulum. Antioxidants & redox signaling, 2012, 16:772-780
  6. Banki N. F., Ver A., Wagner L. J., Vannay A., Degrell P., Prokai A., Gellai R., Lenart L., Szakal D. N., Kenesei E., Rosta K., Reusz G., Szabo A. J., Tulassay T., Baylis C., Fekete A.: Aldosterone antagonists in monotherapy are protective against streptozotocin-induced diabetic nephropathy in rats. PloS one, 2012, 7:e39938
  7. Bence M., Koller J., Sasvari-Szekely M., Keszler G.: Transcriptional modulation of monoaminergic neurotransmission genes by the histone deacetylase inhibitor trichostatin A in neuroblastoma cells. Journal of Neural Transmission, 2012, 119:17-24
  8. Bogel G., Gujdar A., Geiszt M., Lanyi A., Fekete A., Sipeki S., Downward J., Buday L.: Frank-ter Haar syndrome protein Tks4 regulates epidermal growth factor-dependent cell migration. The Journal of biological chemistry, 2012, 287:31321-31329
  9. Borbely G., Huszar M., Varga A., Futosi K., Mocsai A., Orfi L., Idei M., Mandl J., Keri G., Vantus T.: Optimization of important early ADME(T) parameters of NADPH oxidase-4 inhibitor molecules. Med Chem, 2012, 8:174-181
  10. Crul T., Toth N., Piotto S., Literati-Nagy P., Tory K., Haldimann P., Kalmar B., Greensmith L., Torok Z., Balogh G., Gombos I., Campana F., Concilio S., Gallyas F., Nagy G., Berente Z., Gungor B., Peter M., Glatz A., Hunya A., Literati-Nagy Z., Vigh L., Hoogstra-Berends F., Heeres A., Kuipers I., Loen L., Seerden J. P., Zhang D., Meijering R. A., Henning R. H., Brundel B. J., Kampinga H. H., Koranyi L., Szilvassy Z., Mandl J., Sumegi B., Febbraio M. A., Horvath I., Hooper P. L.: Hydroximic Acid Derivatives: Pleiotrophic Hsp Co-Inducers Restoring Homeostasis and Robustness. Current pharmaceutical design, 2012,
  11. Czegle I., Csala M., Mandl J., Benedetti A., Karadi I., Banhegyi G.: G6PT-H6PDH-11betaHSD1 triad in the liver and its implication in the pathomechanism of the metabolic syndrome. World journal of hepatology, 2012, 4:129-138
  12. Csala M., Kereszturi E., Mandl J., Banhegyi G.: The endoplasmic reticulum as the extracellular space inside the cell: role in protein folding and glycosylation. Antioxidants & redox signaling, 2012, 16:1100-1108
  13. Csermely P., Sandhu K. S., Hazai E., Hoksza Z., Kiss H. J., Miozzo F., Veres D. V., Piazza F., Nussinov R.: Disordered proteins and network disorder in network descriptions of protein structure, dynamics and function: hypotheses and a comprehensive review. Current protein & peptide science, 2012, 13:19-33
  14. Dolman M. E., Harmsen S., Pieters E. H., Sparidans R. W., Lacombe M., Szokol B., Orfi L., Keri G., Storm G., Hennink W. E., Kok R. J.: Targeting of a platinum-bound sunitinib analog to renal proximal tubular cells. International journal of nanomedicine, 2012, 7:417-433
  15. Dolman M. E., van Dorenmalen K. M., Pieters E. H., Sparidans R. W., Lacombe M., Szokol B., Orfi L., Keri G., Bovenschen N., Storm G., Hennink W. E., Kok R. J.: Dendrimer-based macromolecular conjugate for the kidney-directed delivery of a multitargeted sunitinib analogue. Macromolecular bioscience, 2012, 12:93-103
  16. Donnelly M. P., Paschou P., Grigorenko E., Gurwitz D., Barta C., Lu R. B., Zhukova O. V., Kim J. J., Siniscalco M., New M., Li H., Kajuna S. L., Manolopoulos V. G., Speed W. C., Pakstis A. J., Kidd J. R., Kidd K. K.: A global view of the OCA2-HERC2 region and pigmentation. Human genetics, 2012, 131:683-696
  17. Fitos I., Simon A., Zsila F., Mady G., Bencsura A., Varga Z., Orfi L., Keri G., Visy J.: Characterization of binding mode of imatinib to human alpha1-acid glycoprotein. International journal of biological macromolecules, 2012, 50:788-795
  18. Futosi K., Nemeth T., Pick R., Vantus T., Walzog B., Mocsai A.: Dasatinib inhibits proinflammatory functions of mature human neutrophils. Blood, 2012, 119:4981-4991
  19. Gaspar M. E., Csermely P.: Rigidity and flexibility of biological networks. Briefings in functional genomics, 2012,
  20. Halmai Z., Dome P., Dobos J., Gonda X., Szekely A., Sasvari-Szekely M., Faludi G., Lazary J.: Peripheral vascular endothelial growth factor level is associated with antidepressant treatment response: Results of a preliminary study. Journal of affective disorders, 2012,
  21. Hegedus C., Truta-Feles K., Antalffy G., Varady G., Nemet K., Ozvegy-Laczka C., Keri G., Orfi L., Szakacs G., Settleman J., Varadi A., Sarkadi B.: Interaction of the EGFR inhibitors gefitinib, vandetanib, pelitinib and neratinib with the ABCG2 multidrug transporter: Implications for the emergence and reversal of cancer drug resistance. Biochemical pharmacology, 2012,
  22. Hegedus T., Gyimesi G., Gaspar M. E., Szalay K. Z., Gangal R., Csermely P.: Potential application of network descriptions for understanding conformational changes and protonation states of ABC transporters. Current pharmaceutical design, 2012,
  23. Karagiannidis I., Rizzo R., Tarnok Z., Wolanczyk T., Hebebrand J., Nothen M. M., Lehmkuhl G., Farkas L., Nagy P., Barta C., Szymanska U., Panteloglou G., Miranda D. M., Feng Y., Sandor P., Barr C., Paschou P.: Replication of association between a SLITRK1 haplotype and Tourette Syndrome in a large sample of families. Molecular psychiatry, 2012, 17:665-668
  24. Klionsky D. J., ….. Banhegyi G., ….. Zuckerbraun B.: Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy, 2012, 8:445-544
  25. Kubinyi E., Vas J., Hejjas K., Ronai Z., Bruder I., Turcsan B., Sasvari-Szekely M., Miklosi A.: Polymorphism in the tyrosine hydroxylase (TH) gene is associated with activity-impulsivity in German Shepherd Dogs. PloS one, 2012, 7:e30271
  26. Lautner G., Balogh Z., Gyurkovics A., Gyurcsanyi R. E., Meszaros T.: Homogeneous assay for evaluation of aptamer-protein interaction. The Analyst, 2012, 137:3929-3931
  27. Literati-Nagy Z., Tory K., Literati-Nagy B., Kolonics A., Torok Z., Gombos I., Balogh G., Vigh L., Jr., Horvath I., Mandl J., Sumegi B., Hooper P. L., Vigh L.: The HSP co-inducer BGP-15 can prevent the metabolic side effects of the atypical antipsychotics. Cell stress & chaperones, 2012,
  28. Literati-Nagy Z., Tory K., Literati-Nagy B., Kolonics A., Vigh L., Jr., Vigh L., Mandl J., Szilvassy Z.: A novel insulin sensitizer drug candidate-BGP-15-can prevent metabolic side effects of atypical antipsychotics. Pathology oncology research : POR, 2012, 18:1071-1076
  29. Marcolongo P., Fulceri R., Giunti R., Margittai E., Banhegyi G., Benedetti A.: The glucose-6-phosphate transport is not mediated by a glucose-6-phosphate/phosphate exchange in liver microsomes. FEBS letters, 2012, 586:3354-3359
  30. Margittai E., Low P., Stiller I., Greco A., Garcia-Manteiga J. M., Pengo N., Benedetti A., Sitia R., Banhegyi G.: Production of H(2)O(2) in the endoplasmic reticulum promotes in vivo disulfide bond formation. Antioxidants & redox signaling, 2012, 16:1088-1099
  31. Marko L., Paragh G., Ugocsai P., Boettcher A., Vogt T., Schling P., Balogh A., Tarabin V., Orso E., Wikonkal N., Mandl J., Remenyik E., Schmitz G.: Keratinocyte ATP binding cassette transporter expression is regulated by ultraviolet light. Journal of photochemistry and photobiology. B, Biology, 2012, 116:79-88
  32. Papp D., Csermely P., Soti C.: A role for SKN-1/Nrf in pathogen resistance and immunosenescence in Caenorhabditis elegans. PLoS pathogens, 2012, 8:e1002673
  33. Papp D., Lenti K., Modos D., Fazekas D., Dul Z., Turei D., Foldvari-Nagy L., Nussinov R., Csermely P., Korcsmaros T.: The NRF2-related interactome and regulome contain multifunctional proteins and fine-tuned autoregulatory loops. FEBS letters, 2012, 586:1795-1802
  34. Paschou P., Stylianopoulou E., Karagiannidis I., Rizzo R., Tarnok Z., Wolanczyk T., Hebebrand J., Nothen M. M., Lehmkuhl G., Farkas L., Nagy P., Szymanska U., Lykidis D., Androutsos C., Tsironi V., Koumoula A., Barta C., Klidonas S., Ypsilantis P., Simopoulos C., Skavdis G., Grigoriou M.: Evaluation of the LIM homeobox genes LHX6 and LHX8 as candidates for Tourette syndrome. Genes, brain, and behavior, 2012, 11:444-451
  35. Sandhu K. S., Li G., Poh H. M., Quek Y. L., Sia Y. Y., Peh S. Q., Mulawadi F. H., Lim J., Sikic M., Menghi F., Thalamuthu A., Sung W. K., Ruan X., Fullwood M. J., Liu E., Csermely P., Ruan Y.: Large-Scale Functional Organization of Long-Range Chromatin Interaction Networks. Cell reports, 2012,
  36. Serfozo Z., Lontay B., Kukor Z., Erdodi F.: Chronic inhibition of nitric oxide synthase activity by N(G)-nitro-l-arginine induces nitric oxide synthase expression in the developing rat cerebellum. Neurochemistry international, 2012, 60:605-615
  37. Spiro Z., Arslan M. A., Somogyvari M., Nguyen M. T., Smolders A., Dancso B., Nemeth N., Elek Z., Braeckman B. P., Csermely P., Soti C.: RNA Interference Links Oxidative Stress to the Inhibition of Heat Stress Adaptation. Antioxidants & redox signaling, 2012,
  38. Szalay-Beko M., Palotai R., Szappanos B., Kovacs I. A., Papp B., Csermely P.: ModuLand plug-in for Cytoscape: determination of hierarchical layers of overlapping network modules and community centrality. Bioinformatics, 2012, 28:2202-2204
  39. Szarka A., Tomasskovics B., Banhegyi G.: The Ascorbate-glutathione-alpha-tocopherol Triad in Abiotic Stress Response. International journal of molecular sciences, 2012, 13:4458-4483
  40. Szeman B., Nagy G., Varga T., Veres-Szekely A., Sasvari M., Fitala D., Szollosi A., Katonai R., Kotyuk E., Somogyi A.: [Changes in cognitive function in patients with diabetes mellitus]. Orvosi hetilap, 2012, 153:323-329
  41. Varga G., Szekely A., Antal P., Sarkozy P., Nemoda Z., Demetrovics Z., Sasvari-Szekely M.: Additive effects of serotonergic and dopaminergic polymorphisms on trait impulsivity. American journal of medical genetics. Part B, Neuropsychiatric genetics, 2012, 159B:281-288

2011

  1. Adori C., Ando R. D., Balazsa T., Soti C., Vas S., Palkovits M., Kovacs G. G., Bagdy G.: Low ambient temperature reveals distinct mechanisms for MDMA-induced serotonergic toxicity and astroglial Hsp27 heat shock response in rat brain. Neurochemistry international, 2011, 59:695-705
  2. Biczo G., Hegyi P., Dosa S., Shalbuyeva N., Berczi S., Sinervirta R., Hracsko Z., Siska A., Kukor Z., Jarmay K., Venglovecz V., Varga I. S., Ivanyi B., Alhonen L., Wittmann T., Gukovskaya A., Takacs T., Rakonczay Z., Jr.: The crucial role of early mitochondrial injury in L-lysine-induced acute pancreatitis. Antioxid Redox Signal, 2011, 15:2669-2681
  3. Burnett C., Valentini S., Cabreiro F., Goss M., Somogyvari M., Piper M. D., Hoddinott M., Sutphin G. L., Leko V., McElwee J. J., Vazquez-Manrique R. P., Orfila A. M., Ackerman D., Au C., Vinti G., Riesen M., Howard K., Neri C., Bedalov A., Kaeberlein M., Soti C., Partridge L., Gems D.: Absence of effects of Sir2 overexpression on lifespan in C. elegans and Drosophila. Nature, 2011, 477:482-485
  4. Chatterjee J., Laufer B., Beck J. G., Helyes Z., Pinter E., Szolcsanyi J., Horvath A., Mandl J., Reubi J. C., Keri G., Kessler H.: N-Methylated sst(2) Selective Somatostatin Cyclic Peptide Analogue as a Potent Candidate for Treating Neurogenic Inflammation. Acs Med Chem Lett, 2011, 2:509-514
  5. Dobozy A., Kerpel-Fronius S., Komoly S., Kovacs L. G., Mandl J., Muszbek L., Petranyi G., Sotonyi P., Udvardy M., Varro A., Vecsei L.: [Complementary therapies–based on the principles of evidence-based medicine. Position statement of the Medical Sciences Section of the Hungarian Academy of Sciences]. Orv Hetil, 2011, 152:1197-1204
  6. Farkas I. J., Korcsmaros T., Kovacs I. A., Mihalik A., Palotai R., Simko G. I., Szalay K. Z., Szalay-Beko M., Vellai T., Wang S., Csermely P.: Network-based tools for the identification of novel drug targets. Science signaling, 2011, 4:pt3
  7. Fruhwirth G. O., Fernandes L. P., Weitsman G., Patel G., Kelleher M., Lawler K., Brock A., Poland S. P., Matthews D. R., Keri G., Barber P. R., Vojnovic B., Ameer-Beg S. M., Coolen A. C., Fraternali F., Ng T.: How Forster resonance energy transfer imaging improves the understanding of protein interaction networks in cancer biology. Chemphyschem, 2011, 12:442-461
  8. Gajda Z., Torok R., Horvath Z., Szantai-Kis C., Orfi L., Keri G., Szente M.: Protein kinase inhibitor as a potential candidate for epilepsy treatment. Epilepsia, 2011, 52:579-588
  9. Gonda X., Fountoulakis K. N., Csukly G., Bagdy G., Pap D., Molnar E., Laszik A., Lazary J., Sarosi A., Faludi G., Sasvari-Szekely M., Szekely A., Rihmer Z.: Interaction of 5-HTTLPR genotype and unipolar major depression in the emergence of aggressive/hostile traits. J Affect Disord, 2011, 132:432-437
  10. Harmsen S., Dolman M. E., Nemes Z., Lacombe M., Szokol B., Pato J., Keri G., Orfi L., Storm G., Hennink W. E., Kok R. J.: Development of a cell-selective and intrinsically active multikinase inhibitor bioconjugate. Bioconjug Chem, 2011, 22:540-545
  11. Holmboe K., Nemoda Z., Fearon R. M., Sasvari-Szekely M., Johnson M. H.: Dopamine D4 receptor and serotonin transporter gene effects on the longitudinal development of infant temperament. Genes Brain Behav, 2011, 10:513-522
  12. Hrabak A., Derzbach L., Csuka I., Bajor T., Korner A.: Role of nitric oxide (NO) metabolism and inflammatory mediators in childhood obesity. Inflammation research : official journal of the European Histamine Research Society … [et al.], 2011, 60:1061-1070
  13. Katonai R. E., Szekely A., Sasvari-Szekely M.: [Effect of dopaminergic and serotonergic gene variants on cognitive performance]. Neuropsychopharmacol Hung, 2011, 13:81-86
  14. Konta L., Szaraz P., Magyar J. E., Revesz K., Banhegyi G., Mandl J., Csala M.: Inhibition of glycoprotein synthesis in the endoplasmic reticulum as a novel anticancer mechanism of (-)-epigallocatechin-3-gallate. Biofactors, 2011, 37:468-476
  15. Korcsmaros T., Szalay M. S., Rovo P., Palotai R., Fazekas D., Lenti K., Farkas I. J., Csermely P., Vellai T.: Signalogs: orthology-based identification of novel signaling pathway components in three metazoans. PLoS One, 2011, 6:e19240
  16. Kovacs-Nagy R., Sarkozy P., Hu J., Guttman A., Sasvari-Szekely M., Ronai Z.: Haplotyping of putative microRNA-binding sites in the SNAP-25 gene. Electrophoresis, 2011, 32:2013-2020
  17. Lanyi A., Barath M., Peterfi Z., Bogel G., Orient A., Simon T., Petrovszki E., Kis-Toth K., Sirokmany G., Rajnavolgyi E., Terhorst C., Buday L., Geiszt M.: The Homolog of the Five SH3-Domain Protein (HOFI/SH3PXD2B) Regulates Lamellipodia Formation and Cell Spreading. PLoS One, 2011, 6:e23653
  18. Magyar Z., Bekesi G., Racz K., Feher J., Schaff Z., Lengyel G., Blazovics A., Illyes G., Szombath D., Hrabak A., Szekacs B., Gergics P., Marczell I., Dinya E., Rigo J., Jr., Tulassay Z.: Increased total scavenger capacity and decreased liver fat content in rats fed dehydroepiandrosterone and its sulphate on a high-fat diet. Gerontology, 2011, 57:343-349
  19. Marcolongo P., Senesi S., Giunti R., Csala M., Fulceri R., Banhegyi G., Benedetti A.: Expression of hexose-6-phosphate dehydrogenase in rat tissues. J Steroid Biochem Mol Biol, 2011, 126:57-64
  20. Margittai E., Sitia R.: Oxidative protein folding in the secretory pathway and redox signaling across compartments and cells. Traffic, 2011, 12:1-8
  21. Marx P., Arany A., Ronai Z., Antal P., Sasvari-Szekely M.: [Genetic variability of the oxytocine receptor: an in silico study]. Neuropsychopharmacol Hung, 2011, 13:139-144
  22. Mihalik A., Csermely P.: Heat shock partially dissociates the overlapping modules of the yeast protein-protein interaction network: a systems level model of adaptation. PLoS computational biology, 2011, 7:e1002187
  23. Nagy G., Rosta K., Szeman B., Sasvari-Szekely M., Somogyi A.: [Clinical aspects of the link between diabetes and depression]. Orv Hetil, 2011, 152:498-504
  24. Nemeth G., Varga Z., Greff Z., Bencze G., Sipos A., Szantai-Kis C., Baska F., Gyuris A., Kelemenics K., Szathmary Z., Minarovits J., Keri G., Orfi L.: Novel, selective CDK9 inhibitors for the treatment of HIV infection. Curr Med Chem, 2011, 18:342-358
  25. Nemoda Z., Horvat-Gordon M., Fortunato C. K., Beltzer E. K., Scholl J. L., Granger D. A.: Assessing genetic polymorphisms using DNA extracted from cells present in saliva samples. BMC medical research methodology, 2011, 11:170
  26. Nemoda Z., Szekely A., Sasvari-Szekely M.: Psychopathological aspects of dopaminergic gene polymorphisms in adolescence and young adulthood. Neurosci Biobehav Rev, 2011, 35:1665-1686
  27. Nussinov R., Tsai C. J., Csermely P.: Allo-network drugs: harnessing allostery in cellular networks. Trends in pharmacological sciences, 2011, 32:686-693
  28. Patel G. S., Kiuchi T., Lawler K., Ofo E., Fruhwirth G. O., Kelleher M., Shamil E., Zhang R., Selvin P. R., Santis G., Spicer J., Woodman N., Gillett C. E., Barber P. R., Vojnovic B., Keri G., Schaeffter T., Goh V., O’Doherty M. J., Ellis P. A., Ng T.: The challenges of integrating molecular imaging into the optimization of cancer therapy. Integr Biol (Camb), 2011, 3:603-631
  29. Prokai A., Fekete A., Banki N. F., Muller V., Ver A., Degrell P., Rusai K., Wagner L., Vannay A., Rosta M., Heemann U., Langer R. M., Tulassay T., Reusz G., Szabo A. J.: Renoprotective effect of erythropoietin in rats subjected to ischemia/reperfusion injury: gender differences. Surgery, 2011, 150:39-47
  30. Sonkoly B., Bardoczy V., Meszaros T.: Expression and purification of active protein kinases from wheat germ extracts. Methods Mol Biol, 2011, 779:55-63
  31. Szekely A., Balota D. A., Duchek J. M., Nemoda Z., Vereczkei A., Sasvari-Szekely M.: Genetic factors of reaction time performance: DRD4 7-repeat allele associated with slower responses. Genes Brain Behav, 2011, 10:129-136
  32. Varga G., Szekely A., Sasvari-Szekely M.: Candidate gene studies of dopaminergic and serotonergic polymorphisms. Neuropsychopharmacol Hung, 2011, 13:93-101
  33. Zsigmond L., Tomasskovics B., Deak V., Rigo G., Szabados L., Banhegyi G., Szarka A.: Enhanced activity of galactono-1,4-lactone dehydrogenase and ascorbate-glutathione cycle in mitochondria from complex III deficient Arabidopsis. Plant Physiol Biochem, 2011, 49:809-815

2010

  1. Balogh Z., Lautner G., Bardoczy V., Komorowska B., Gyurcsanyi R. E., Meszaros T.: Selection and versatile application of virus-specific aptamers. FASEB J, 2010, 24:4187-4195
  2. Borbely G., Szabadkai I., Horvath Z., Marko P., Varga Z., Breza N., Baska F., Vantus T., Huszar M., Geiszt M., Hunyady L., Buday L., Orfi L., Keri G.: Small-molecule inhibitors of NADPH oxidase 4. J Med Chem, 2010, 53:6758-6762
  3. Breitkopf S. B., Oppermann F. S., Keri G., Grammel M., Daub H.: Proteomics analysis of cellular imatinib targets and their candidate downstream effectors. J Proteome Res, 2010, 9:6033-6043
  4. Buday L., Tompa P.: Accessory proteins in signal transduction: scaffold proteins and beyond. FEBS J, 2010, 277:4347
  5. Buday L., Tompa P.: Functional classification of scaffold proteins and related molecules. FEBS J, 2010, 277:4348-4355
  6. Csala M., Margittai E., Banhegyi G.: Redox control of endoplasmic reticulum function. Antioxid Redox Signal, 2010, 13:77-108
  7. Csermely P., Palotai R., Nussinov R.: Induced fit, conformational selection and independent dynamic segments: an extended view of binding events. Trends Biochem Sci, 2010, 35:539-546
  8. d’Angelo I., Garcia-Fuentes M., Parajo Y., Welle A., Vantus T., Horvath A., Bokonyi G., Keri G., Alonso M. J.: Nanoparticles Based on PLGA:Poloxamer Blends for the Delivery of Proangiogenic Growth Factors. Mol Pharm, 2010,
  9. d’Angelo I., Parajo Y., Horvath A., Keri G., La Rotonda M. I., Alonso M. J.: Improved delivery of angiogenesis inhibitors from PLGA:poloxamer blend micro- and nanoparticles. J Microencapsul, 2010, 27:57-66
  10. Dancso B., Spiro Z., Arslan M. A., Nguyen M. T., Papp D., Csermely P., Soti C.: The heat shock connection of metabolic stress and dietary restriction. Curr Pharm Biotechnol, 2010, 11:139-145
  11. de Boussac H., Ratajewski M., Sachrajda I., Koblos G., Tordai A., Pulaski L., Buday L., Varadi A., Aranyi T.: The ERK1/2-hepatocyte nuclear factor 4alpha axis regulates human ABCC6 gene expression in hepatocytes. J Biol Chem, 2010, 285:22800-22808
  12. Demetrovics Z., Varga G., Szekely A., Vereczkei A., Csorba J., Balazs H., Hoffman K., Sasvari-Szekely M., Barta C.: Association between Novelty Seeking of opiate-dependent patients and the catechol-O-methyltransferase Val(158)Met polymorphism. Compr Psychiatry, 2010, 51:510-515
  13. Holmboe K., Nemoda Z., Fearon R. M., Csibra G., Sasvari-Szekely M., Johnson M. H.: Polymorphisms in dopamine system genes are associated with individual differences in attention in infancy. Dev Psychol, 2010, 46:404-416
  14. Huszar M., Varga A., Horvath A., Lorand T., Agocs A., Idei M., Mandl J., Vantus T., Keri G.: Comparative characterization of experimental and calculated lipophilicity and anti-tumour activity of isochromanone derivatives. Curr Med Chem, 2010, 17:321-333
  15. Kenessey I., Keszthelyi M., Kramer Z., Berta J., Adam A., Dobos J., Mildner M., Flachner B., Cseh S., Barna G., Szokol B., Orfi L., Keri G., Dome B., Klepetko W., Timar J., Tovari J.: Inhibition of c-Met with the specific small molecule tyrosine kinase inhibitor SU11274 decreases growth and metastasis formation of experimental human melanoma. Curr Cancer Drug Targets, 2010, 10:332-342
  16. Kereszturi E., Kalman F. S., Kardon T., Csala M., Banhegyi G.: Decreased prereceptorial glucocorticoid activating capacity in starvation due to an oxidative shift of pyridine nucleotides in the endoplasmic reticulum. FEBS Lett, 2010, 584:4703-4708
  17. Korcsmaros T., Farkas I. J., Szalay M. S., Rovo P., Fazekas D., Spiro Z., Bode C., Lenti K., Vellai T., Csermely P.: Uniformly curated signaling pathways reveal tissue-specific cross-talks and support drug target discovery. Bioinformatics, 2010, 26:2042-2050
  18. Kovacs I. A., Palotai R., Szalay M. S., Csermely P.: Community landscapes: an integrative approach to determine overlapping network module hierarchy, identify key nodes and predict network dynamics. PLoS One, 2010, 5:
  19. Kukor Z., Valent S.: [Nitric oxide and preeclampsia.]. Orv Hetil, 2010, 151:2125-2135
  20. Lautner G., Balogh Z., Bardoczy V., Meszaros T., Gyurcsanyi R. E.: Aptamer-based biochips for label-free detection of plant virus coat proteins by SPR imaging. Analyst, 2010, 135:918-926
  21. Magnet S., Hartkoorn R. C., Szekely R., Pato J., Triccas J. A., Schneider P., Szantai-Kis C., Orfi L., Chambon M., Banfi D., Bueno M., Turcatti G., Keri G., Cole S. T.: Leads for antitubercular compounds from kinase inhibitor library screens. Tuberculosis (Edinb), 2010, 90:354-360
  22. Margittai E., Banhegyi G.: Oxidative folding in the endoplasmic reticulum: towards a multiple oxidant hypothesis? FEBS Lett, 2010, 584:2995-2998
  23. Mozes V., Bence M., Sasvari-Szekely M., Keszler G.: [Dopamine D4 receptor hypoxia sensitivity and child psychiatric disorders]. Neuropsychopharmacol Hung, 2010, 12:289-293
  24. Nagy G., Szarka A., Lotz G., Doczi J., Wunderlich L., Kiss A., Jemnitz K., Veres Z., Banhegyi G., Schaff Z., Sumegi B., Mandl J.: BGP-15 inhibits caspase-independent programmed cell death in acetaminophen-induced liver injury. Toxicol Appl Pharmacol, 2010, 243:96-103
  25. Nemoda Z., Lyons-Ruth K., Szekely A., Bertha E., Faludi G., Sasvari-Szekely M.: Association between dopaminergic polymorphisms and borderline personality traits among at-risk young adults and psychiatric inpatients. Behav Brain Funct, 2010, 6:4
  26. Petak I., Schwab R., Orfi L., Kopper L., Keri G.: Integrating molecular diagnostics into anticancer drug discovery. Nat Rev Drug Discov, 2010, 9:523-535
  27. Radnai L., Rapali P., Hodi Z., Suveges D., Molnar T., Kiss B., Becsi B., Erdodi F., Buday L., Kardos J., Kovacs M., Nyitray L.: Affinity, avidity, and kinetics of target sequence binding to LC8 dynein light chain isoforms. J Biol Chem, 2010, 285:38649-38657
  28. Rahman O. A., Sasvari-Szekely M., Szekely A., Faludi G., Guttman A., Nemoda Z.: Analysis of a polymorphic microRNA target site in the purinergic receptor P2RX7 gene. Electrophoresis, 2010, 31:1790-1795
  29. Rosendahl J., Ronai Z., Kovacs P., Teich N., Wittenburg H., Bluher M., Stumvoll M., Mossner J., Keim V., Bradbury A. R., Sahin-Toth M.: Sequence analysis of the human tyrosylprotein sulfotransferase-2 gene in subjects with chronic pancreatitis. Pancreatology, 2010, 10:165-172
  30. Schreiber T. B., Mausbacher N., Keri G., Cox J., Daub H.: An integrated phosphoproteomics work flow reveals extensive network regulation in early lysophosphatidic acid signaling. Mol Cell Proteomics, 2010, 9:1047-1062
  31. Senesi S., Csala M., Marcolongo P., Fulceri R., Mandl J., Banhegyi G., Benedetti A.: Hexose-6-phosphate dehydrogenase in the endoplasmic reticulum. Biol Chem, 2010, 391:1-8
  32. Senesi S., Legeza B., Balazs Z., Csala M., Marcolongo P., Kereszturi E., Szelenyi P., Egger C., Fulceri R., Mandl J., Giunti R., Odermatt A., Banhegyi G., Benedetti A.: Contribution of fructose-6-phosphate to glucocorticoid activation in the endoplasmic reticulum: possible implication in the metabolic syndrome. Endocrinology, 2010, 151:4830-4839
  33. Sharma K., Kumar C., Keri G., Breitkopf S. B., Oppermann F. S., Daub H.: Quantitative analysis of kinase-proximal signaling in lipopolysaccharide-induced innate immune response. J Proteome Res, 2010, 9:2539-2549
  34. Szaraz P., Banhegyi G., Benedetti A.: Altered redox state of luminal pyridine nucleotides facilitates the sensitivity towards oxidative injury and leads to endoplasmic reticulum stress dependent autophagy in HepG2 cells. Int J Biochem Cell Biol, 2010, 42:157-166
  35. Szekely A., Kovacs-Nagy R., Banyai E. I., Gosi-Greguss A. C., Varga K., Halmai Z., Ronai Z., Sasvari-Szekely M.: Association between hypnotizability and the catechol-O-methyltransferase (COMT) polymorphism. Int J Clin Exp Hypn, 2010, 58:301-315
  36. Szekeres M., Nadasy G. L., Turu G., Supeki K., Szidonya L., Buday L., Chaplin T., Clark A. J., Hunyady L.: Angiotensin II-induced expression of brain-derived neurotrophic factor in human and rat adrenocortical cells. Endocrinology, 2010, 151:1695-1703
  37. Tiszlavicz Z., Szabolcs A., Takacs T., Farkas G., Kovacs-Nagy R., Szantai E., Sasvari-Szekely M., Mandi Y.: Polymorphisms of beta defensins are associated with the risk of severe acute pancreatitis. Pancreatology, 2010, 10:483-490
  38. Varga Z., Berenyi S., Szokol B., Orfi L., Keri G., Petak I., Hoell A., Bota A.: A closer look at the structure of sterically stabilized liposomes: a small-angle X-ray scattering study. J Phys Chem B, 2010, 114:6850-6854

2009

  1. Antal M. A., Bode C., Csermely P.: Perturbation waves in proteins and protein networks: applications of percolation and game theories in signaling and drug design. Current protein & peptide science, 2009, 10:161-172
  2. Balazs A., Csizmok V., Buday L., Rakacs M., Kiss R., Bokor M., Udupa R., Tompa K., Tompa P.: High levels of structural disorder in scaffold proteins as exemplified by a novel neuronal protein, CASK-interactive protein1. Febs J, 2009, 276:3744-3756
  3. Banhegyi G., Csala M., Benedetti A.: Hexose-6-phosphate dehydrogenase: linking endocrinology and metabolism in the endoplasmic reticulum. Journal of molecular endocrinology, 2009, 42:283-289
  4. Bence M., Kereszturi E., Mozes V., Sasvari-Szekely M., Keszler G.: Hypoxia-induced transcription of dopamine D3 and D4 receptors in human neuroblastoma and astrocytoma cells. BMC neuroscience, 2009, 10:92
  5. Blasko B., Banlaki Z., Gyapay G., Pozsonyi E., Sasvari-Szekely M., Rajczy K., Fust G., Szilagyi A.: Linkage analysis of the C4A/C4B copy number variation and polymorphisms of the adjacent steroid 21-hydroxylase gene in a healthy population. Molecular immunology, 2009, 46:2623-2629
  6. Donko A., Orient A., Szabo P. T., Nemeth G., Vantus T., Keri G., Orfi L., Hunyady L., Buday L., Geiszt M.: Detection of hydrogen peroxide by lactoperoxidase-mediated dityrosine formation. Free radical research, 2009, 43:440-445
  7. Eros D., Orfi L., Csuka I., Keri G., Hrabak A.: Binding specificity of the L-arginine transport systems in mouse macrophages and human cells overexpressing the cationic amino acid transporter hCAT-1. Amino acids, 2009, 36:483-492
  8. Fabian T. K., Csermely P., Fabian G., Fejerdy P.: Spondyloarthropathies and bone resorption: a possible role of heat shock protein (Hsp70). Acta physiologica Hungarica, 2009, 96:149-155
  9. Hegedus C., Ozvegy-Laczka C., Apati A., Magocsi M., Nemet K., Orfi L., Keri G., Katona M., Takats Z., Varadi A., Szakacs G., Sarkadi B.: Interaction of nilotinib, dasatinib and bosutinib with ABCB1 and ABCG2: implications for altered anti-cancer effects and pharmacological properties. British journal of pharmacology, 2009, 158:1153-1164
  10. Hegyi H., Buday L., Tompa P.: Intrinsic structural disorder confers cellular viability on oncogenic fusion proteins. PLoS Comput Biol, 2009, 5:e1000552
  11. Hegymegi-Barakonyi B., Eros D., Szantai-Kis C., Breza N., Banhegyi P., Szabo G. V., Varkondi E., Petak I., Orfi L., Keri G.: Tyrosine kinase inhibitors – small molecular weight compounds inhibiting EGFR. Current opinion in molecular therapeutics, 2009, 11:308-321
  12. Hejjas K., Kubinyi E., Ronai Z., Szekely A., Vas J., Miklosi A., Sasvari-Szekely M., Kereszturi E.: Molecular and behavioral analysis of the intron 2 repeat polymorphism in the canine dopamine D4 receptor gene. Genes Brain Behav, 2009, 8:330-336
  13. Hejjas K., Szekely A., Domotor E., Halmai Z., Balogh G., Schilling B., Sarosi A., Faludi G., Sasvari-Szekely M., Nemoda Z.: Association between depression and the Gln460Arg polymorphism of P2RX7 gene: a dimensional approach. Am J Med Genet B Neuropsychiatr Genet, 2009, 150B:295-299
  14. Herczenik E., Varga Z., Eros D., Mako V., Oroszlan M., Rugonfalvi-Kiss S., Romics L., Fust G., Keri G., Orfi L., Cervenak L.: Protein kinase inhibitor-induced endothelial cell cytotoxicity and its prediction based on calculated molecular descriptors. Journal of receptor and signal transduction research, 2009, 29:75-83
  15. Kelleher M. T., Fruhwirth G., Patel G., Ofo E., Festy F., Barber P. R., Ameer-Beg S. M., Vojnovic B., Gillett C., Coolen A., Keri G., Ellis P. A., Ng T.: The potential of optical proteomic technologies to individualize prognosis and guide rational treatment for cancer patients. Targeted oncology, 2009, 4:235-252
  16. Kereszturi E., Kiraly O., Sahin-Toth M.: Minigene analysis of intronic variants in common SPINK1 haplotypes associated with chronic pancreatitis. Gut, 2009, 58:545-549
  17. Kereszturi E., Sahin-Toth M.: Intracellular autoactivation of human cationic trypsinogen mutants causes reduced trypsinogen secretion and acinar cell death. J Biol Chem, 2009, 284:33392-33399
  18. Kereszturi E., Szmola R., Kukor Z., Simon P., Weiss F. U., Lerch M. M., Sahin-Toth M.: Hereditary pancreatitis caused by mutation-induced misfolding of human cationic trypsinogen: a novel disease mechanism. Human mutation, 2009, 30:575-582
  19. Kiss H. J., Mihalik A., Nanasi T., Ory B., Spiro Z., Soti C., Csermely P.: Ageing as a price of cooperation and complexity: self-organization of complex systems causes the gradual deterioration of constituent networks. Bioessays, 2009, 31:651-664
  20. Kotyuk E., Kovacs-Nagy R., Faludi G., Urban R., Ronai Z., Sasvari-Szekely M., Szekely A.: [Association between nicotine dependence and the -521 promoter polymorfism of the dopamine D4 receptor in patients with major depression]. Neuropsychopharmacol Hung, 2009, 11:59-67
  21. Kovacs-Nagy R., Hu J., Ronai Z., Sasvari-Szekely M.: SNAP-25: a novel candidate gene in psychiatric genetics. Neuropsychopharmacol Hung, 2009, 11:89-94
  22. Literati-Nagy B., Kulcsar E., Literati-Nagy Z., Buday B., Peterfai E., Horvath T., Tory K., Kolonics A., Fleming A., Mandl J., Koranyi L.: Improvement of insulin sensitivity by a novel drug, BGP-15, in insulin-resistant patients: a proof of concept randomized double-blind clinical trial. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 2009, 41:374-380
  23. Magyar J. E., Gamberucci A., Konta L., Margittai E., Mandl J., Banhegyi G., Benedetti A., Csala M.: Endoplasmic reticulum stress underlying the pro-apoptotic effect of epigallocatechin gallate in mouse hepatoma cells. Int J Biochem Cell Biol, 2009, 41:694-700
  24. Mandl J., Meszaros T., Banhegyi G., Hunyady L., Csala M.: Endoplasmic reticulum: nutrient sensor in physiology and pathology. Trends in endocrinology and metabolism: TEM, 2009, 20:194-201
  25. Mandl J., Szarka A., Banhegyi G.: Vitamin C: update on physiology and pharmacology. British journal of pharmacology, 2009, 157:1097-1110
  26. Margittai E., Csala M., Mandl J., Banhegyi G.: Participation of Low Molecular Weight Electron Carriers in Oxidative Protein Folding. International journal of molecular sciences, 2009, 10:1346-1359
  27. Nagy G., Kovacs-Nagy R., Kereszturi E., Somogyi A., Szekely A., Nemeth N., Hosszufalusi N., Panczel P., Ronai Z., Sasvari-Szekely M.: Association of hypoxia inducible factor-1 alpha gene polymorphism with both type 1 and type 2 diabetes in a Caucasian (Hungarian) sample. BMC medical genetics, 2009, 10:79
  28. Nemoda Z., Angyal N., Tarnok Z., Gadoros J., Sasvari-Szekely M.: Carboxylesterase 1 gene polymorphism and methylphenidate response in ADHD. Neuropharmacology, 2009, 57:731-733
  29. Oh M. A., Choi S., Lee M. J., Choi M. C., Lee S. A., Ko W., Cance W. G., Oh E. S., Buday L., Kim S. H., Lee J. W.: Specific tyrosine phosphorylation of focal adhesion kinase mediated by Fer tyrosine kinase in suspended hepatocytes. Biochimica et biophysica acta, 2009, 1793:781-791
  30. Oppermann F. S., Gnad F., Olsen J. V., Hornberger R., Greff Z., Keri G., Mann M., Daub H.: Large-scale proteomics analysis of the human kinome. Mol Cell Proteomics, 2009, 8:1751-1764
  31. Racz G., Szabo A., Ver A., Zador E.: The slow sarco/endoplasmic reticulum Ca2+ -ATPase declines independently of slow myosin in soleus muscle of diabetic rats. Acta biochimica Polonica, 2009, 56:487-493
  32. Reinl T., Nimtz M., Hundertmark C., Johl T., Keri G., Wehland J., Daub H., Jansch L.: Quantitative phosphokinome analysis of the Met pathway activated by the invasin internalin B from Listeria monocytogenes. Mol Cell Proteomics, 2009, 8:2778-2795
  33. Ronai Z., Witt H., Rickards O., Destro-Bisol G., Bradbury A. R., Sahin-Toth M.: A common African polymorphism abolishes tyrosine sulfation of human anionic trypsinogen (PRSS2). The Biochemical journal, 2009, 418:155-161
  34. Rosta K., Molvarec A., Enzsoly A., Nagy B., Ronai Z., Fekete A., Sasvari-Szekely M., Rigo J., Jr., Ver A.: Association of extracellular superoxide dismutase (SOD3) Ala40Thr gene polymorphism with pre-eclampsia complicated by severe fetal growth restriction. European journal of obstetrics, gynecology, and reproductive biology, 2009, 142:134-138
  35. Rosta K., Tulassay E., Enzsoly A., Ronai K., Szantho A., Pandics T., Fekete A., Mandl P., Ver A.: Insulin induced translocation of Na+/K+ -ATPase is decreased in the heart of streptozotocin diabetic rats. Acta Pharmacol Sin, 2009, 30:1616-1624
  36. Sharma K., Weber C., Bairlein M., Greff Z., Keri G., Cox J., Olsen J. V., Daub H.: Proteomics strategy for quantitative protein interaction profiling in cell extracts. Nature methods, 2009, 6:741-744
  37. Simko G. I., Gyurko D., Veres D. V., Nanasi T., Csermely P.: Network strategies to understand the aging process and help age-related drug design. Genome medicine, 2009, 1:90
  38. Spangler G., Johann M., Ronai Z., Zimmermann P.: Genetic and environmental influence on attachment disorganization. J Child Psychol Psychiatry, 2009, 50:952-961
  39. Szabo T. G., Palotai R., Antal P., Tokatly I., Tothfalusi L., Lund O., Nagy G., Falus A., Buzas E. I.: Critical role of glycosylation in determining the length and structure of T cell epitopes. Immunome Res, 2009, 5:4
  40. Szantai E., Elek Z., Guttman A., Sasvari-Szekely M.: Candidate gene copy number analysis by PCR and multicapillary electrophoresis. Electrophoresis, 2009, 30:1098-1101
  41. Toth M.: [Myoanabolic steroids and selective androgen receptor modulators: mechanism of action and perspectives]. Orv Hetil, 2009, 150:2051-2059
  42. Varga A., Huszar M., Dobos Z., Kiss E., Horvath A., Idei M.: Characterisation of mixed lithium dodecyl sulphate/lithium perfluorooctanesulphonate pseudo-stationary phases in MEKC. Electrophoresis, 2009, 30:1923-1928
  43. Vereczkei A., Sasvari-Szekely M., Barta C.: [The role of genetic variants of the dopaminergic system in heroin dependence]. Neuropsychopharmacol Hung, 2009, 11:95-101
  44. Zsila F., Fitos I., Bencze G., Keri G., Orfi L.: Determination of human serum alpha1-acid glycoprotein and albumin binding of various marketed and preclinical kinase inhibitors. Curr Med Chem, 2009, 16:1964-1977

2008

  1. Banhegyi G., Mandl J., Csala M.: Redox-based endoplasmic reticulum dysfunction in neurological diseases. Journal of neurochemistry, 2008, 107:20-34
  2. Banhegyi P., Waczek F., Szekelyhidi Z., Hegymegi-Barakonyi B., Keri G., Orfi L.: [Novel method for the synthesis of carboxamides from low reactivity esters: synthesis of 2-acylamino-1-benzothiophene-3-carboxamides]. Acta Pharm Hung, 2008, 78:75-78
  3. Bardoczy V., Geczi V., Sawasaki T., Endo Y., Meszaros T.: A set of ligation-independent in vitro translation vectors for eukaryotic protein production. BMC biotechnology, 2008, 8:32
  4. Blasko B., Kolka R., Thorbjornsdottir P., Sigurdarson S. T., Sigurdsson G., Ronai Z., Sasvari-Szekely M., Bodvarsson S., Thorgeirsson G., Prohaszka Z., Kovacs M., Fust G., Arason G. J.: Low complement C4B gene copy number predicts short-term mortality after acute myocardial infarction. International immunology, 2008, 20:31-37
  5. Breza N., Pato J., Orfi L., Hegymegi-Barakonyi B., Banhegyi P., Varkondi E., Borbely G., Petak I., Keri G.: Synthesis and characterization of novel quinazoline type inhibitors for mutant and wild-type EGFR and RICK kinases. J Recept Signal Transduct Res, 2008, 28:361-373
  6. Buday L., Downward J.: Many faces of Ras activation. Biochim Biophys Acta, 2008, 1786:178-187
  7. Czegle I., Margittai E., Senesi S., Benedetti A., Banhegyi G.: Different expression and distribution of 11beta-hydroxysteroid dehydrogenase type 1 in obese and lean animal models of type 2 diabetes. Acta Physiol Hung, 2008, 95:419-424
  8. Csermely P.: Creative elements: network-based predictions of active centres in proteins and cellular and social networks. Trends Biochem Sci, 2008, 33:569-576
  9. Daniel S., Bradley G., Longshaw V. M., Soti C., Csermely P., Blatch G. L.: Nuclear translocation of the phosphoprotein Hop (Hsp70/Hsp90 organizing protein) occurs under heat shock, and its proposed nuclear localization signal is involved in Hsp90 binding. Biochim Biophys Acta, 2008, 1783:1003-1014
  10. Daub H., Olsen J. V., Bairlein M., Gnad F., Oppermann F. S., Korner R., Greff Z., Keri G., Stemmann O., Mann M.: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle. Mol Cell, 2008, 31:438-448
  11. Elekes K., Helyes Z., Kereskai L., Sandor K., Pinter E., Pozsgai G., Tekus V., Banvolgyi A., Nemeth J., Szuts T., Keri G., Szolcsanyi J.: Inhibitory effects of synthetic somatostatin receptor subtype 4 agonists on acute and chronic airway inflammation and hyperreactivity in the mouse. European journal of pharmacology, 2008, 578:313-322
  12. Eros D., Szantai-Kis C., Kiss R., Keri G., Hegymegi-Barakonyi B., Kovesdi I., Orfi L.: Structure -activity relationships of PDE5 inhibitors. Curr Med Chem, 2008, 15:1570-1585
  13. Fabian T. K., Fejerdy P., Csermely P.: Salivary Genomics, Transcriptomics and Proteomics: The Emerging Concept of the Oral Ecosystem and their Use in the Early Diagnosis of Cancer and other Diseases. Curr Genomics, 2008, 9:11-21
  14. Fekete A., Rosta K., Wagner L., Prokai A., Degrell P., Ruzicska E., Vegh E., Toth M., Ronai K., Rusai K., Somogyi A., Tulassay T., Szabo A. J., Ver A.: Na+,K+-ATPase is modulated by angiotensin II in diabetic rat kidney–another reason for diabetic nephropathy? J Physiol, 2008, 586:5337-5348
  15. Hegymegi-Barakonyi B., Szekely R., Varga Z., Kiss R., Borbely G., Nemeth G., Banhegyi P., Pato J., Greff Z., Horvath Z., Meszaros G., Marosfalvi J., Eros D., Szantai-Kis C., Breza N., Garavaglia S., Perozzi S., Rizzi M., Hafenbradl D., Ko M., Av-Gay Y., Klebl B. M., Orfi L., Keri G.: Signalling inhibitors against Mycobacterium tuberculosis–early days of a new therapeutic concept in tuberculosis. Curr Med Chem, 2008, 15:2760-2770
  16. Horemans N., Szarka A., De Bock M., Raeymaekers T., Potters G., Levine M., Banhegyi G., Guisez Y.: Dehydroascorbate and glucose are taken up into Arabidopsis thaliana cell cultures by two distinct mechanisms. FEBS Lett, 2008, 582:2714-2718
  17. Horvath B., Hortobagyi L., Lenzser G., Schweer H., Hrabak A., Sandor P., Benyo Z.: Carbon monoxide-prostaglandin E2 interaction in the hypothalamic circulation. Neuroreport, 2008, 19:1601-1604
  18. Hrabak A., Bajor T., Csuka I.: The effect of various inflammatory agents on the phagocytosis and cytokine profile of mouse and rat macrophages. Inflamm Res, 2008, 57:75-83
  19. Hrabak A., Bajor T., Meszaros G.: The inhibitory effect of various indolyl amino acid derivatives on arginase activity in macrophages. Amino acids, 2008, 34:293-300
  20. Kardon T., Senesi S., Marcolongo P., Legeza B., Banhegyi G., Mandl J., Fulceri R., Benedetti A.: Maintenance of luminal NADPH in the endoplasmic reticulum promotes the survival of human neutrophil granulocytes. FEBS Lett, 2008, 582:1809-1815
  21. Kereszturi E., Tarnok Z., Bognar E., Lakatos K., Farkas L., Gadoros J., Sasvari-Szekely M., Nemoda Z.: Catechol-O-methyltransferase Val158Met polymorphism is associated with methylphenidate response in ADHD children. Am J Med Genet B Neuropsychiatr Genet, 2008, 147B:1431-1435
  22. Lizak B., Csala M., Benedetti A., Banhegyi G.: The translocon and the non-specific transport of small molecules in the endoplasmic reticulum (Review). Molecular membrane biology, 2008, 25:95-101
  23. Marcolongo P., Senesi S., Gava B., Fulceri R., Sorrentino V., Margittai E., Lizak B., Csala M., Banhegyi G., Benedetti A.: Metyrapone prevents cortisone-induced preadipocyte differentiation by depleting luminal NADPH of the endoplasmic reticulum. Biochemical pharmacology, 2008, 76:382-390
  24. Margittai E., Banhegyi G.: Isocitrate dehydrogenase: A NADPH-generating enzyme in the lumen of the endoplasmic reticulum. Archives of biochemistry and biophysics, 2008, 471:184-190
  25. Margittai E., Low P., Szarka A., Csala M., Benedetti A., Banhegyi G.: Intraluminal hydrogen peroxide induces a permeability change of the endoplasmic reticulum membrane. FEBS Lett, 2008, 582:4131-4136
  26. Miyazaki A., Tsuda Y., Fukushima S., Yokoi T., Vantus T., Bokonyi G., Szabo E., Horvath A., Keri G., Okada Y.: New cyclic somatostatin analogues containing a pyrazinone ring: importance of Tyr for antiproliferative activity. Bioorg Med Chem Lett, 2008, 18:6199-6201
  27. Miyazaki A., Tsuda Y., Fukushima S., Yokoi T., Vantus T., Bokonyi G., Szabo E., Horvath A., Keri G., Okada Y.: Synthesis of somatostatin analogues containing C-terminal adamantane and their antiproliferative properties. J Med Chem, 2008, 51:5121-5124
  28. Nagy G., Ronai Z., Somogyi A., Sasvari-Szekely M., Rahman O. A., Mate A., Varga T., Nemoda Z.: P2RX7 Gln460Arg polymorphism is associated with depression among diabetic patients. Prog Neuropsychopharmacol Biol Psychiatry, 2008, 32:1884-1888
  29. Palotai R., Szalay M. S., Csermely P.: Chaperones as integrators of cellular networks: changes of cellular integrity in stress and diseases. IUBMB life, 2008, 60:10-18
  30. Pinter F., Papay J., Almasi A., Sapi Z., Szabo E., Kanya M., Tamasi A., Jori B., Varkondi E., Moldvay J., Szondy K., Keri G., Dominici M., Conte P., Eckhardt S., Kopper L., Schwab R., Petak I.: Epidermal growth factor receptor (EGFR) high gene copy number and activating mutations in lung adenocarcinomas are not consistently accompanied by positivity for EGFR protein by standard immunohistochemistry. J Mol Diagn, 2008, 10:160-168
  31. Putics A., Vegh E. M., Csermely P., Soti C.: Resveratrol induces the heat-shock response and protects human cells from severe heat stress. Antioxidants & redox signaling, 2008, 10:65-75
  32. Putics A., Vodros D., Malavolta M., Mocchegiani E., Csermely P., Soti C.: Zinc supplementation boosts the stress response in the elderly: Hsp70 status is linked to zinc availability in peripheral lymphocytes. Exp Gerontol, 2008, 43:452-461
  33. Sahin-Toth M., Hegyi P., Toth M.: [Genetic risk factors in chronic pancreatitis]. Orv Hetil, 2008, 149:1683-1688
  34. Santhosh S., Witt H., te Morsche R. H., Nemoda Z., Molnar T., Pap A., Jansen J. B., Drenth J. P.: A loss of function polymorphism (G191R) of anionic trypsinogen (PRSS2) confers protection against chronic pancreatitis. Pancreas, 2008, 36:317-320
  35. Sarosi A., Gonda X., Balogh G., Domotor E., Szekely A., Hejjas K., Sasvari-Szekely M., Faludi G.: Association of the STin2 polymorphism of the serotonin transporter gene with a neurocognitive endophenotype in major depressive disorder. Prog Neuropsychopharmacol Biol Psychiatry, 2008, 32:1667-1672
  36. Senesi S., Marcolongo P., Manini I., Fulceri R., Sorrentino V., Csala M., Banhegyi G., Benedetti A.: Constant expression of hexose-6-phosphate dehydrogenase during differentiation of human adipose-derived mesenchymal stem cells. Journal of molecular endocrinology, 2008, 41:125-133
  37. Serfozo Z., Kiss P. B., Kukor Z., Lontay B., Palatka K., Varga V., Erdodi F., Elekes K.: Thyroid hormones affect the level and activity of nitric oxide synthase in rat cerebral cortex during postnatal development. Neurochemical research, 2008, 33:569-578
  38. Speed W. C., O’Roak B. J., Tarnok Z., Barta C., Pakstis A. J., State M. W., Kidd K. K.: Haplotype evolution of SLITRK1, a candidate gene for Gilles de la Tourette syndrome. Am J Med Genet B Neuropsychiatr Genet, 2008, 147B:463-466
  39. Spiro Z., Kovacs I. A., Csermely P.: Drug-therapy networks and the prediction of novel drug targets. Journal of biology, 2008, 7:20
  40. Szarka A., Horemans N., Passarella S., Tarcsay A., Orsi F., Salgo A., Banhegyi G.: Demonstration of an intramitochondrial invertase activity and the corresponding sugar transporters of the inner mitochondrial membrane in Jerusalem artichoke (Helianthus tuberosus L.) tubers. Planta, 2008, 228:765-775
  41. Szatmari T., Huszty G., Desaknai S., Spasokoukotskaja T., Sasvari-Szekely M., Staub M., Esik O., Safrany G., Lumniczky K.: Adenoviral vector transduction of the human deoxycytidine kinase gene enhances the cytotoxic and radiosensitizing effect of gemcitabine on experimental gliomas. Cancer gene therapy, 2008, 15:154-164
  42. Szekely R., Waczek F., Szabadkai I., Nemeth G., Hegymegi-Barakonyi B., Eros D., Szokol B., Pato J., Hafenbradl D., Satchell J., Saint-Joanis B., Cole S. T., Orfi L., Klebl B. M., Keri G.: A novel drug discovery concept for tuberculosis: inhibition of bacterial and host cell signalling. Immunology letters, 2008, 116:225-231
  43. Tejeda M., Gaal D., Hullan L., Csuka O., Schwab R., Szokoloczi O., Keri G. Y.: Continuous administration of the somatostatin structural derivative /TT-232/ by subcutaneously implanted osmotic pump improves the efficacy and potency of antitumor therapy in different mouse and human tumor models. Anticancer Res, 2008, 28:2769-2774
  44. Varkondi E., Pinter F., Robert K., Schwab R., Breza N., Orfi L., Keri G., Petak I.: Biochemical assay-based selectivity profiling of clinically relevant kinase inhibitors on mutant forms of EGF receptor. J Recept Signal Transduct Res, 2008, 28:295-306
  45. Wang S., Szalay M. S., Zhang C., Csermely P.: Learning and innovative elements of strategy adoption rules expand cooperative network topologies. PLoS One, 2008, 3:e1917
  46. Wunderlich L., Paragh G., Wikonkal N. M., Banhegyi G., Karpati S., Mandl J.: UVB induces a biphasic response of HIF-1alpha in cultured human keratinocytes. Experimental dermatology, 2008, 17:335-342
  47. Zhang Y. X., Knyazev P. G., Cheburkin Y. V., Sharma K., Knyazev Y. P., Orfi L., Szabadkai I., Daub H., Keri G., Ullrich A.: AXL is a potential target for therapeutic intervention in breast cancer progression. Cancer research, 2008, 68:1905-1915
  48. Zsigmond L., Rigo G., Szarka A., Szekely G., Otvos K., Darula Z., Medzihradszky K. F., Koncz C., Koncz Z., Szabados L.: Arabidopsis PPR40 connects abiotic stress responses to mitochondrial electron transport. Plant physiology, 2008, 146:1721-1737

2007

  1. Arason G. J., Kramer J., Blaskó B., Kolka R., Thorbjornsdottir P., Einarsdottir K., Sigfusdottir A., Sigurdarson S. T., Sigurdsson G., Rónai Z., Prohászka Z., Sasvári-Székely M., Bodvarsson S., Thorgeirsson G., Füst G.: Smoking and a complement gene polymorphism interact in promoting cardiovascular disease morbidity and mortality. Clin. Exp. Immunol., 2007, 149:132-138
  2. Bánhegyi G., Baumeister P., Benedetti A., Dong D., Fu Y., Lee A. S., Li J., Mao C., Margittai E., Ni M., Paschen W., Piccirella S., Senesi S., Sitia R., Wang M., Yang W.: Endoplasmic reticulum stress. Ann. N. Y. Acad. Sci., 2007, 1113:58-71
  3. Bánhegyi G., Benedetti A., Csala M., Mandl J.: Stress on redox. FEBS Lett., 2007, 581:3634-3640
  4. Blaskó B., Széplaki G., Varga L., Rónai Z., Prohászka Z., Sasvári-Székely M., Visy B., Farkas H., Füst G.: Relationship between copy number of genes (C4A, C4B) encoding the fourth component of complement and the clinical course of hereditary angioedema (HAE). Mol. Immunol., 2007, 44:2667-2674
  5. Böde C., Kovács I. A., Szalay M. S., Palotai R., Korcsmáros T., Csermely P.: Network analysis of protein dynamics. FEBS Lett., 2007, 581:2776-2782
  6. Buday L., Downward J.: Roles of cortactin in tumor pathogenesis. Biochim. Biophys. Acta, 2007, 1775:263-273
  7. Csala M., Marcolongo P., Lizak B., Senesi S., Margittai E., Fulceri R., Magyar J. E., Benedetti A., Bánhegyi G.: Transport and transporters in the endoplasmic reticulum. Biochim. Biophys. Acta, 2007, 1768:1325-1341
  8. Csala M., Margittai E., Senesi S., Gamberucci A., Bánhegyi G., Mandl J., Benedetti A.: Inhibition of hepatic glucose 6-phosphatase system by the green tea flavanol epigallocatechin gallate. FEBS Lett., 2007, 581:1693-1698
  9. Csermely P., Sőti C., Blatch G. L.: Chaperones as parts of cellular networks. Adv. Exp. Med. Biol., 2007, 594:55-63
  10. Dömötör E., Sárosi A., Balogh G., Székely A., Héjjas K., Sasvári-Székely M., Faludi G.: Association of neurocognitive endophenotype and STin2 polymorphism in major depressive disorder. Neuropsychopharmacol. Hung., 2007, 9:53-62
  11. Fábian G., Müller O., Kovács S., Nguyen M. T., Fábian T. K., Fejerdy P., Csermely P.: Attitude toward Death. Does it Influence Dental Fear? Ann. N. Y. Acad. Sci., 2007, 1113:339-349
  12. Fábian T. K., Fejerdy P., Nguyen M. T., Sőti C., Csermely P.: Potential immunological functions of salivary Hsp70 in mucosal and periodontal defense mechanisms. Arch. Immunol. Ther. Exp. (Warsz), 2007, 55:91-98
  13. Gervai J., Novak A., Lakatos K., Tóth I., Danis I., Rónai Z., Nemoda Z., Sasvári-Székely M., Bureau J. F., Bronfman E., Lyons-Ruth K.: Infant Genotype May Moderate Sensitivity to Maternal Affective Communications: Attachment Disorganization, Quality of Care, and the DRD4 Polymorphism. Soc. Neurosci., 2007, 2:307-319
  14. Giunti R., Gamberucci A., Fulceri R., Bánhegyi G., Benedetti A.: Both translocon and a cation channel are involved in the passive Ca2+ leak from the endoplasmic reticulum: a mechanistic study on rat liver microsomes. Arch. Biochem. Biophys., 2007, 462:115-121
  15. Gonzalo T., Beljaars L., van de Bovenkamp M., Temming K., van Loenen A. M., Reker-Smit C., Meijer D. K., Lacombe M., Opdam F., Kéri G., Őrfi L., Poelstra K., Kok R. J.: Local inhibition of liver fibrosis by specific delivery of a platelet-derived growth factor kinase inhibitor to hepatic stellate cells. J. Pharmacol. Exp. Ther., 2007, 321:856-865
  16. Hallgas B., Dobos Z., Agócs A., Idei M., Kéri G., Lorand T., Mészáros G.: Lipophilicity and antiproliferative activity profiling of 2-benzylidencycloalkanones. J. Chromatogr. B Analyt. Technol. Biomed. Life Sci., 2007, 856:148-155
  17. Héjjas K., Vas J., Kubinyi E., Sasvári-Székely M., Miklósi A., Rónai Z.: Novel repeat polymorphisms of the dopaminergic neurotransmitter genes among dogs and wolves. Mamm Genome, 2007, 18:871-879
  18. Héjjas K., Vas J., Topal J., Szántai E., Rónai Z., Székely A., Kubinyi E., Horváth Z., Sasvári-Székely M., Miklósi A.: Association of polymorphisms in the dopamine D4 receptor gene and the activity-impulsivity endophenotype in dogs. Anim. Genet., 2007, 38:629-633
  19. Hortobágyi L., Kis B., Hrabák A., Horváth B., Huszty G., Schweer H., Benyó B., Sandor P., Busija D. W., Benyó Z.: Adaptation of the hypothalamic blood flow to chronic nitric oxide deficiency is independent of vasodilator prostanoids. Brain Res., 2007, 1131:129-137
  20. Kereszturi E., Király O., Csapó Z., Tárnok Z., Gádoros J., Sasvári-Székely M., Nemoda Z.: Analysis of the dopamine D4 receptor gene variants in attention deficit hyperactivity disorder. Neuropsychopharmacol. Hung., 2007, 9:11-18
  21. Kereszturi E., Király O., Csapó Z., Tárnok Z., Gádoros J., Sasvári-Székely M., Nemoda Z.: Association between the 120-bp duplication of the dopamine D4 receptor gene and attention deficit hyperactivity disorder: genetic and molecular analyses. Am. J. Med. Genet. B Neuropsychiatr. Genet., 2007, 144:231-236
  22. Korcsmáros T., Kovács I. A., Szalay M. S., Csermely P.: Molecular chaperones: The modular evolution of cellular networks. J. Biosci., 2007, 32:441-446
  23. Kovacs M., Vincze B., Horvath J. E., Seprodi J.: Structure-activity study on the LH- and FSH-releasing and anticancer effects of gonadotropin-releasing hormone (GnRH)-III analogs. Peptides, 2007, 28:821-829
  24. Kovács S., Fábián T. K., Gaál V., Csermely P.: A kapcsolati hálózat egyes paramétereinek hatása a szorongásra. Tájékozódó vizsgálat 14-18 éves középiskolás populáción. Magyar Pszichológiai Szemle, 2007, 62:193-201
  25. Li H., Mukherjee N., Soundararajan U., Tarnok Z., Barta C., Khaliq S., Mohyuddin A., Kajuna S. L., Mehdi S. Q., Kidd J. R., Kidd K. K.: Geographically separate increases in the frequency of the derived ADH1B*47His allele in eastern and western Asia. Am J Hum Genet, 2007, 81:842-846
  26. Lyons-Ruth K., Holmes B. M., Sasvári-Székely M., Rónai Z., Nemoda Z., Pauls D.: Serotonin transporter polymorphism and borderline or antisocial traits among low-income young adults. Psychiatr. Genet., 2007, 17:339-343
  27. Mandl J., Bánhegyi G.: Endoplasmic reticulum stress–common pathomechanism of different diseases? Orv. Hetil., 2007, 148:1779-1785
  28. Marcolongo P., Piccirella S., Senesi S., Wunderlich L., Gerin I., Mandl J., Fulceri R., Bánhegyi G., Benedetti A.: The glucose-6-phosphate transporter-hexose-6-phosphate dehydrogenase-11beta-hydroxysteroid dehydrogenase type 1 system of the adipose tissue. Endocrinology, 2007, 148:2487-2495
  29. Millson S. H., Truman A. W., Rácz A., Hu B., Panaretou B., Nuttall J., Mollapour M., Sőti C., Piper P. W.: Expressed as the sole Hsp90 of yeast, the alpha and beta isoforms of human Hsp90 differ with regard to their capacities for activation of certain client proteins, whereas only Hsp90beta generates sensitivity to the Hsp90 inhibitor radicicol. The FEBS journal, 2007, 274:4453-4463
  30. Molvarec A., Vér A., Fekete A., Rosta K., Derzbach L., Derzsy Z., Karádi I., Rigó J., Jr.: Association between estrogen receptor alpha (ESR1) gene polymorphisms and severe preeclampsia. Hypertens. Res., 2007, 30:205-211
  31. Nagy G., Kardon T., Wunderlich L., Szarka A., Kiss A., Schaff Z., Bánhegyi G., Mandl J.: Acetaminophen induces ER dependent signaling in mouse liver. Arch. Biochem. Biophys., 2007, 459:273-279
  32. Révész K., Tüttő A., Margittai E., Bánhegyi G., Magyar J. E., Mandl J., Csala M.: Glucuronide transport across the endoplasmic reticulum membrane is inhibited by epigallocatechin gallate and other green tea polyphenols. Int. J. Biochem. Cell Biol., 2007, 39:922-930
  33. Rutherford S., Knapp J. R., Csermely P.: Hsp90 and developmental networks. Adv. Exp. Med. Biol., 2007, 594:190-197
  34. Schwab R., Micsik T., Szokolóczi O., Schafer E., Tihanyi B., Tihanyi T., Kupcsulik P., Diófalvi K., Mersich T., Besznyák I., Jr., Zarand A., Mihalik R., Sarkadi B., Kéri G., Pap A., Jakab F., Kopper L., Peták I.: Functional evaluation of multidrug resistance transporter activity in surgical samples of solid tumors. Assay Drug Dev. Technol., 2007, 5:541-550
  35. Serfőző Z., Kiss P. B., Kukor Z., Lontay B., Palatka K., Varga V., Erdodi F., Elekes K.: Thyroid Hormones affect the Level and Activity of Nitric Oxide Synthase in Rat Cerebral Cortex during Postnatal Development. Neurochem. Res., 2007,
  36. Simon Á., Kéri G., Kardos J.: Comparison of the binding modes of TT-232 in somatostatin receptors type 1 and 4. Journal of Molecular Structure: THEOCHEM, 2007, 816:73-76
  37. Sőti C., Csermely P.: Aging cellular networks: chaperones as major participants. Exp. Gerontol., 2007, 42:113-119
  38. Sőti C., Csermely P.: Protein stress and stress proteins: implications in aging and disease. J. Biosci., 2007, 32:511-515
  39. Steták A., Veress R., Ovádi J., Csermely P., Kéri G., Ullrich A.: Nuclear translocation of the tumor marker pyruvate kinase M2 induces programmed cell death. Cancer Res., 2007, 67:1602-1608
  40. Szalay M. S., Kovács I. A., Korcsmáros T., Böde C., Csermely P.: Stress-induced rearrangements of cellular networks: Consequences for protection and drug design. FEBS Lett., 2007, 581:3675-3680
  41. Szarka A., Horemans N., Kovács Z., Gróf P., Mayer M., Bánhegyi G.: Dehydroascorbate reduction in plant mitochondria is coupled to the respiratory electron transfer chain. Physiol. Plantarum, 2007, 129:225-232
  42. Szilágyi A., Barta C., Boor K., Székely A., Demetrovics Z., Csorba J., Kalász H., Sasvári-Székely M.: The potential role of childhood ADHD in the development of heroin dependence at a young age. Neuropsychopharmacol. Hung., 2007, 9:69-75
  43. Szilágyi A., Blaskó B., Szilassy D., Füst G., Sasvári-Székely M., Rónai Z.: Analysis of the genetic variability of complement component C4 by real-time PCR. Neuropsychopharmacol. Hung., 2007, 9:5-10
  44. Tárnok Z., Rónai Z., Gervai J., Kereszturi E., Gádoros J., Sasvári-Székely M., Nemoda Z.: Dopaminergic candidate genes in Tourette syndrome: association between tic severity and 3′ UTR polymorphism of the dopamine transporter gene. Am. J. Med. Genet. B Neuropsychiatr. Genet., 2007, 144:900-905
  45. Tejeda M., Gaal D., Hullan L., Schwab R., Szokoloczi O., Keri G.: Antitumor activity of the somatostatin structural derivative (TT-232), against mouse and human melanoma tumor models. Anticancer Res, 2007, 27:4015-4019
  46. Wissing J., Jansch L., Nimtz M., Dieterich G., Hornberger R., Kéri G., Wehland J., Daub H.: Proteomics analysis of protein kinases by target class-selective prefractionation and tandem mass spectrometry. Mol. Cell Proteomics, 2007, 6:537-547
  47. Zebisch A., Czernilofsky A. P., Kéri G., Smigelskaite J., Sill H., Troppmair J.: Signaling through RAS-RAF-MEK-ERK: from basics to bedside. Curr. Med. Chem., 2007, 14:601-623

2006

  1. Arslan M. A., Csermely P., Soti C.: Protein homeostasis and molecular chaperones in aging. Biogerontology, 2006, 7:383-389
  2. Birkas E., Horvath J., Lakatos K., Nemoda Z., Sasvari-Szekely M., Winkler I., Gervai J.: Association between dopamine D4 receptor (DRD4) gene polymorphisms and novelty-elicited auditory event-related potentials in preschool children. Brain Res., 2006, 1103:150-158
  3. Csala M., Banhegyi G., Benedetti A.: Endoplasmic reticulum: a metabolic compartment. FEBS Lett., 2006, 580:2160-2165
  4. Csermely P., Soti C.: Cellular networks and the aging process. Arch. Physiol. Biochem., 2006, 112:60-64
  5. Csermely P., Soti C.: Az öregedésről – a hálózatok szemszögéből. Magyar Tudomány, 2006, 11:1309-1312
  6. Czegle I., Piccirella S., Senesi S., Csala M., Mandl J., Banhegyi G., Fulceri R., Benedetti A.: Cooperativity between 11beta-hydroxysteroid dehydrogenase type 1 and hexose-6-phosphate dehydrogenase is based on a common pyridine nucleotide pool in the lumen of the endoplasmic reticulum. Mol. Cell. Endocrinol., 2006, 248:24-25
  7. Feher E., Batbayar B., Ver A., Zelles T.: Changes of the Different Neuropeptide-Containing Nerve Fibers and Immunocells in the Diabetic Rat’s Alimentary Tract. Ann. N. Y. Acad. Sci., 2006, 1084:280-295
  8. Fekete A., Vannay A., Ver A., Rusai K., Muller V., Reusz G., Tulassay T., Szabo A. J.: Sex differences in heat shock protein 72 expression and localization in rats following renal ischemia-reperfusion injury. Am. J. Physiol. Renal Physiol., 2006, 291:F806-F811
  9. Fekete A., Ver A., Bogi K., Treszl A., Rigo J.,Jr: Is preeclampsia associated with higher frequency of HSP70 gene polymorphisms? Eur. J. Obstet. Gynecol. Reprod. Biol., 2006, 126:197-200
  10. Gamberucci A., Konta L., Colucci A., Giunti R., Magyar J. E., Mandl J., Banhegyi G., Benedetti A., Csala M.: Green tea flavonols inhibit glucosidase II. Biochem. Pharmacol., 2006, 72:640-646
  11. Hollosy F., Valko K., Hersey A., Nunhuck S., Keri G., Bevan C.: Estimation of volume of distribution in humans from high throughput HPLC-based measurements of human serum albumin binding and immobilized artificial membrane partitioning. J. Med. Chem., 2006, 49:6958-6971
  12. Hrabák A., Bajor T., Körner A.: Alkalmas-e a nitrogén-monoxid metabolizmusának vizsgálata az 1-es tipusú diabetes mellitus elõrejelzésére? Diabetologia Hungarica, 2006, 14:163-170
  13. Hrabak A.: Common ligands of G-protein-coupled receptors and arginine-utilizing enzymes. Br. J. Pharmacol., 2006, 147:835-837
  14. Hrabak A., Bajor T., Csuka I.: The effect of various inflammatory agents on the alternative metabolic pathways of arginine in mouse and rat macrophages. Inflamm. Res., 2006, 55:23-31
  15. Hrabak A., Bokonyi G., Orfi L., Bajor T., Keri G.: Comparison of the cytotoxic effects of receptor tyrosine kinase inhibitors on macrophage functions; possible side effects in the immune defense. Immunol. Lett., 2006, 107:169-175
  16. Hrabak A., Csuka I., Bajor T., Csatary L. K.: The cytotoxic anti-tumor effect of MTH-68/H, a live attenuated Newcastle disease virus is mediated by the induction of nitric oxide synthesis in rat peritoneal macrophages in vitro. Cancer Lett., 2006, 231:279-289
  17. Hrabak A., Szabo A., Bajor T., Korner A.: Differences in the nitric oxide metabolism in streptozotocin-treated rats and children suffering from Type 1 diabetes. Life Sci., 2006, 78:1362-1370
  18. Illes A., Enyedi B., Tamas P., Balazs A., Bogel G., Buday L.: Inducible phosphorylation of cortactin is not necessary for cortactin-mediated actin polymerisation. Cell. Signal., 2006, 18:830-840
  19. Illes A., Enyedi B., Tamas P., Balazs A., Bogel G., Melinda, Lukacs, Buday L.: Cortactin is required for integrin-mediated cell spreading. Immunol. Lett., 2006, 104:124-130
  20. Kardon T., Nagy G., Csala M., Kiss A., Schaff Z., Nagy P. L., Wunderlich L., Banhegyi G., Mandl J.: Influence of BGP-15, a nicotinic amidoxime derivative, on the vascularization and growth of murine hepatoma xenografts. Anticancer Res., 2006, 26:1023-1028
  21. Kardon T., Noel G., Vertommen D., Schaftingen E. V.: Identification of the gene encoding hydroxyacid-oxoacid transhydrogenase, an enzyme that metabolizes 4-hydroxybutyrate. FEBS Lett., 2006, 580:2347-2350
  22. Kereszturi E., Kiraly O., Barta C., Molnar N., Sasvari-Szekely M., Csapo Z.: No direct effect of the -521 C/T polymorphism in the human dopamine D4 receptor gene promoter on transcriptional activity. BMC Mol. Biol., 2006, 7:18
  23. Keszler G., Spasokoukotskaja T., Sasvari-Szekely M., Eriksson S., Staub M.: Deoxycytidine kinase is reversibly phosphorylated in normal human lymphocytes. Nucleosides Nucleotides Nucleic Acids, 2006, 25:1147-1151
  24. Kiraly O., Guan L., Szepessy E., Toth M., Kukor Z., Sahin-Toth M.: Expression of human cationic trypsinogen with an authentic N terminus using intein-mediated splicing in aminopeptidase P deficient Escherichia coli. Protein Expr. Purif., 2006, 48:104-111
  25. Lizak B., Czegle I., Csala M., Benedetti A., Mandl J., Banhegyi G.: Translocon pores in the endoplasmic reticulum are permeable to small anions. Am. J. Physiol. Cell. Physiol., 2006, 291:C511-C517
  26. Nardai G., Vegh E. M., Prohaszka Z., Csermely P.: Chaperone-related immune dysfunction: an emergent property of distorted chaperone networks. Trends Immunol., 2006, 27:74-79
  27. Nemoda Z., Sahin-Toth M.: Chymotrypsin C (caldecrin) stimulates autoactivation of human cationic trypsinogen. J. Biol. Chem., 2006, 281:11879-11886
  28. Pal C., Papp B., Lercher M. J., Csermely P., Oliver S. G., Hurst L. D.: Chance and necessity in the evolution of minimal metabolic networks. Nature, 2006, 440:667-670
  29. Papp E., Csermely P.: Chemical chaperones: mechanisms of action and potential use. Handb. Exp. Pharmacol., 2006, 172:405-416
  30. Papp E., Szaraz P., Korcsmaros T., Csermely P.: Changes of endoplasmic reticulum chaperone complexes, redox state, and impaired protein disulfide reductase activity in misfolding alpha1-antitrypsin transgenic mice. FASEB J., 2006, 20:1018-1020
  31. Piccirella S., Czegle I., Lizak B., Margittai E., Senesi S., Papp E., Csala M., Fulceri R., Csermely P., Mandl J., Benedetti A., Banhegyi G.: Uncoupled redox systems in the lumen of the endoplasmic reticulum. Pyridine nucleotides stay reduced in an oxidative environment. J. Biol. Chem., 2006, 281:4671-4677
  32. Prakash J., Sandovici M., Saluja V., Lacombe M., Schaapveld R. Q., de Borst M. H., van Goor H., Henning R. H., Proost J. H., Moolenaar F., Keri G., Meijer D. K., Poelstra K., Kok R. J.: Intracellular delivery of the p38 mitogen-activated protein kinase inhibitor SB202190 [4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)1H-imidazole] in renal tubular cells: a novel strategy to treat renal fibrosis. J. Pharmacol. Exp. Ther., 2006, 319:8-19
  33. Rigo J., Szendei G., Rosta K., Fekete A., Bogi K., Molvarec A., Ronai Z., Ver A.: Leptin receptor gene polymorphisms in severely pre-eclamptic women. Gynecol. Endocrinol., 2006, 22:521-525
  34. Sahin-Toth M., Kukor Z., Nemoda Z.: Human cationic trypsinogen is sulfated on Tyr154. FEBS J., 2006, 273:5044-5050
  35. Sipeki S., Bander E., Parker P. J., Farago A.: PKCalpha reduces the lipid kinase activity of the p110alpha/p85alpha PI3K through the phosphorylation of the catalytic subunit. Biochem. Biophys. Res. Commun., 2006, 339:122-125
  36. Soti C., Csermely P.: Pharmacological modulation of the heat shock response. Handb. Exp. Pharmacol., 2006, 172:417-436
  37. Spasokoukotskaja T., Csapo Z., Virga S., Sasvari-Szekely M., Staub M., Keszler G.: Effects of intracellular calcium chelation and pifithrin-alpha on deoxynucleotide metabolism in human lymphocytes. Nucleosides Nucleotides Nucleic Acids, 2006, 25:1181-1184
  38. Staub M., Stenger A., Sumeg R., Spasokoukotskaja T., Fairbanks L. D., Simmonds H. A., Keszler G.: The neuroleptic chlorpromazine inhibits the cationic and stimulates the anionic phospholipid precursor synthesis in human lymphocytes. Nucleosides Nucleotides Nucleic Acids, 2006, 25:1133-1139
  39. Szantai E., Guttman A.: Genotyping with microfluidic devices. Electrophoresis, 2006, 27:4896-4903
  40. Szantai E., Ronai Z., Sasvari-Szekely M., Bonn G., Guttman A.: Multicapillary electrophoresis analysis of single-nucleotide sequence variations in the deoxycytidine kinase gene. Clin. Chem., 2006, 52:1756-1762
  41. Szantai E., Ronai Z., Sasvari-Szekely M., Guttman A.: Haplotyping of the deoxycytidine kinase gene by multicapillary electrophoresis. Anal. Biochem., 2006, 352:148-150
  42. Szantai-Kis C., Kovesdi I., Eros D., Banhegyi P., Ullrich A., Keri G., Orfi L.: Prediction oriented QSAR modelling of EGFR inhibition. Curr. Med. Chem., 2006, 13:277-287
  43. Szarka A., Bánhegyi G., Mayer M.: A mitokondrium szerepe a növényi sejt C-vitaminbioszintézisében és redoxállapotának szabályozásában. Biokémia, 2006, 2:33-38
  44. Szilagyi A., Blasko B., Ronai Z., Fust G., Sasvari-Szekely M., Guttman A.: Rapid quantification of human complement component C4A and C4B genes by capillary gel electrophoresis. Electrophoresis, 2006, 27:1437-1443
  45. Szilagyi A., Blasko B., Szilassy D., Fust G., Sasvari-Szekely M., Ronai Z.: Real-time PCR quantification of human complement C4A and C4B genes. BMC Genet., 2006, 7:1
  46. Szilagyi A., Boor K., Orosz I., Szantai E., Szekely A., Kalasz H., Sasvari-Szekely M., Farkas V.: Contribution of serotonin transporter gene polymorphisms to pediatric migraine. Headache, 2006, 46:478-485
  47. Teich N., Rosendahl J., Toth M., Mossner J., Sahin-Toth M.: Mutations of human cationic trypsinogen (PRSS1) and chronic pancreatitis. Hum. Mutat., 2006, 27:721-730
  48. Tejeda M., Gaal D., Hullan L., Csuka O., Schwab R., Szokoloczi O., Keri G.: A comparison of the tumor growth inhibitory effect of intermittent and continuous administration of the somatostatin structural derivative TT-232 in various human tumor models. Anticancer Res., 2006, 26:3011-3015
  49. Tejeda M., Gaal D., Hullan L., Hegymegi-Barakonyi B., Keri G.: Evaluation of the antitumor efficacy of the somatostatin structural derivative TT-232 on different tumor models. Anticancer Res., 2006, 26:3477-3483
  50. Temming K., Lacombe M., Schaapveld R. Q., Orfi L., Keri G., Poelstra K., Molema G., Kok R. J.: Rational design of RGD-albumin conjugates for targeted delivery of the VEGF-R kinase inhibitor PTK787 to angiogenic endothelium. ChemMedChem, 2006, 1:1200-1203
  51. Temming K., Lacombe M., van der Hoeven P., Prakash J., Gonzalo T., Dijkers E. C., Orfi L., Keri G., Poelstra K., Molema G., Kok R. J.: Delivery of the p38 MAPkinase inhibitor SB202190 to angiogenic endothelial cells: development of novel RGD-equipped and PEGylated drug-albumin conjugates using platinum(II)-based drug linker technology. Bioconjug. Chem., 2006, 17:1246-1255
  52. Toth-Petroczy A., Szilagyi A., Ronai Z., Sasvari-Szekely M., Guttman A.: Validation of a tentative microsatellite marker for the dopamine D4 receptor gene by capillary gel electrophoresis. J. Chromatogr. A, 2006, 1130:201-205
  53. Turu G., Szidonya L., Gaborik Z., Buday L., Spat A., Clark A. J., Hunyady L.: Differential beta-arrestin binding of AT1 and AT2 angiotensin receptors. FEBS Lett., 2006, 580:41-45
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2005

  1. Ágoston V., Csermely P., Pongor S.: Multiple weak hits confuse complex systems: A transcriptional regulatory network as an example. Physical Review „E”, 2005, 71:051909-1-051909-7
  2. Bánhegyi G.: A likopin – egy természetes antioxidáns. Orvosi Hetilap, 2005, 146 évf. 3l:1621-1624
  3. Brehmer D., Greff Z., Gold K., Blencke S., Kurtenbach A., Weber M., Müller S., Klebl B., Cotten M., Kéri Gy., Wissing J., Daub H.: Cellular targets of gefitinib. Cancer Res., 2005, 65:379-382
  4. Buschbeck M., Hofbauer S., Di Croce L., Kéri Gy., Ullrich A.: Abl-kinase-sensitive levels of ERK5 and its intrinsic basal activity contribute to leukaemia cell survival. Eur. Mol. Biol. Org. (EMBO Rep) 2005, 6:63-69
  5. Csala M., Senesi S., Bánhegyi G., Mandl J., Benedetti A.: Characterization of sulfate transport in the hepatic endoplasmic reticulum. Arch. Biochem. Biophys., 2005, 440:173-180
  6. Csermely P., Ágoston V., Pongor S.: The efficiency of multi-target drugs: the network approach might help drug design. Trends Pharmacol. Sci., 2005, 26:178-182
  7. Demeter A., Sziller I., Csapó Zs., Olah J., Keszler G., Jeney A., Papp Z., Staub M.: Molecular prognostic markers in recurrent and in non-recurrent epithelial ovarian cancer. Anticancer Res., 2005, 25:2885-2890
  8. Dobos Zs., Kiss É., Hallgas B., Kéri Gy., Idei M.: Micellar proportion: A parameter to compare the hydrophobicity of the pseudostationary phases or that of the analytes in micellar electrokinetic chromatography. Electrophoresis, 2005, 26:849-857
  9. Elkind B.N., Szentpétery Zs., Apáti Á., Özvegy-Laczka Cs., Várady Gy., Ujhelly O., Szabó K., Homolya L., Váradi A., Buday L., Kéri Gy., Német K., Sarkadi B.: Multidrug transporter ABCG2 prevents tumor cell death induced by the epidermal growth factor receptor inhibitor iressa (ZD1839, Gefitinib). Cancer Res., 2005, 65:1770-1777
  10. Gervai J., Nemoda Zs., Lakatos K., Rónai Zs., Tóth I., Ney K., Sasvári-Székely M.: Transmission disequilibrium tests confirm the link between DRD4 gene polymorphism and infant attachment. Am. J. Med. Gen. ”Part B”, 2005, 132B:126-130
  11. Godl K., Gruss O.J., Eickhoff J., Wissing J., Blencke S., Weber M., Degen H., Brehmer D., Őrfi L., Horváth Z., Kéri Gy., Müller S., Cotten M., Ullrick A., Daub H.: Proteomic characterization of the angiogenesis inhibitor SU6668 reveals multiple impacts on cellular kinase signaling. Cancer Res., 2005, 65:6919-6926
  12. Hallgas B., Dobos Zs., Ősz E., Hollósy F., Schwab R.E., Szabó E.Z., Erős D., Idei M., Kéri Gy., Lóránd T.: Characterization of lipophilicity and antiproliferative activity of E-2-Arylmethylene-1-tetralones and their heteroanalogues. J. Chromatogr. ”B” , 2005, 819:283-291
  13. Hofstaetter J.G., Wunderlich L., Samuel R.E., Saad F.A., Choi Y.H., Glimcher M.J.: Systemic hypoxia alters gene expression levels of structural proteins and growth factors in knee joint cartilage. Biochem. Biophys. Res. Comm., 2005, 330:386-394
  14. Kéri Gy., Schwab R., Szokolóczi O., Szüts T., Szolcsányi J.: TT-232: An anti-tumour and anti-inflammatory peptide therapeutic in clinical development. Int. J. Pept. Res. Therapeut., 2005, 11:3-15
  15. Kéri Gy., Székelyhidi Zs., Bánhegyi P., Varga Z., Hegymegi-Barakonyi B., Szántai-Kis Cs., Hafenbradl D., Klebl B., Muller G., Ullrich A., Erős D., Horváth Z., Greff Z., Marosfalvi J., Pató J.., Szabadkai I., Szilágyi I., Szegedi Zs., Varga I., Wáczek F., Őrfi L.: Drug discovery int he kinase inhibitory field using the nested chemical libraryTM technology. ASSAY Drug Dev. Techn., 2005, 3:543-551
  16. Keszler G., Virga Sz., Spasokoukotskaja T., Bauer P.I., Sasvári-Székely M.,Staub M.: Activation of deoxycytidine kinase by deoxyadenosine: Implications in deoxyadenosine-mediated cytotoxicity. Arch. Biochem. Biophys., 2005, 436:69-77
  17. Kittel Á., Kiss A. L., Müllner N., Matkó I., Sperlágh B.: Expression of NTPDase1 and caveolins in human cardiovascular disease. Histochem. Cell Biol., 2005, 124:52-59
  18. Kovács I.A., Szalay M.S., Csermely P.: Water and molecular chaperones act as weak links of protein folding networks: Energy landscape and punctuated equilibrium changes point towards a game theory of proteins. FEBS Lett., 2005, 579:2254-2260
  19. Margittai É.: Az aszkorbát és a tokoferol szerepe a fehérjék diszulfidhídjainak kialakulásában. Biokémia, 2005, 29:2-6
  20. Margittai É., Bánhegyi G., Kiss A., Nagy G., Mandl J., Schaff Zs., Csala M.: Scurvy leads to endoplasmic reticulum stress and apoptosis in the liver of guinea pigs. J. Nutr., 2005, 135:2530-2534
  21. Nardai G., Stadler K., Papp E., Korcsmáros T., Jakus J., Csermely P.: Diabetic changes in the redox status of the microsomal protein folding machinery. Biochem. Biopys. Res. Commun., 2005, 334:787-795
  22. Papp E., Nardai G., Mandl J., Bánhegyi G., Csermely P.: FAD oxidizes the ERO1-PDI electron transfer chain: The role of membrane integrity. Biochem. Biophys. Res. Commun., 2005, 338:938-945
  23. Proctor C.J., Sőti Cs., Boys R.J., Gillespie C.S., Shanley D.P., Wilkinson D.J., Kirkwood T.B.L.: Modelling the actions of chaperones and their role in ageing. Mech. Ageing Dev., 2005, 126:119-131
  24. Saad F.A., Salih E., Wunderlich L., Flückiger R., Glimcher M.J.: Prokaryotic expression of bone sialoprotein and identification of casein kinase II phosphorylation sites. Biochem. Biophys. Res. Com., 2005, 333:443-447
  25. Sarang Zs., Molnár P., Németh T., Gomba Sz., Kardon T., Melino G., Cotecchia S., Fésüs L., Szondy Zs.: Tissue transglutanimase (TG2) acting as G protein protects hepatocytes against fas-mediated cell death in mice. Hepatology, 2005, 42:578-587
  26. Schwab R., Pintér F., Moldavy J., Papay J., Strausz J., Kopper L., Kéri Gy., Pap Á., Peták I., Oreskovich K., Mangel L.: Modern treatment of lung cancer: Case l. Amplification and mutation of the epidermal growth factor receptor in metastatic lung cancer with remission from gefitinib. J. Clin. Oncol., 2005, 23:7736-7738
  27. Senesi S., Marcolongo P., Kardon T., Bucci G., Sukhodub A., Burchell A., Benedetti A., Fulceri R.: Immunodetection of the expression of microsomal proteins encoded by the glucose 6-phospahate transporter gene. Biochem. J., 2005, 389:57-62
  28. Sőti Cs., Pál Cs., Papp B., Csermely P.: Molecular chaperones as regulatory elements of cellular networks. Curr. Opin. Cell. Biol., 2005, 17:210-215
  29. Sőti Cs., Nagy E., Giricz Z., Vigh L., Csermely P., Ferdinandy P.: Heat shock protein as emerging therapeutic targets. Br. J. Pharmacol., 2005, 146:769-780
  30. Staines A.G., Burchell B., Bánhegyi G., Mandl J., Csala M.: Application of high-performance liquid chromatography-electrospray ionization-mass spectrometry to measure microsomal membrane transport of glucuronides. Anal. Biochem., 2005, 342:45-52
  31. Sukopp M., Schwab R., Marinelli L., Biron E., Heller M., Várkondi E., Pap Á., Novellino E., Kéri Gy., Kessler H.: Structure-activity relationship studies optimizing the antiproliferative activity of novel cyclic somatostatin analogues containing a restrained cyclic b-amino acid. J. Med. Chem., 2005, 48:2916-2926
  32. Szakács Z., Béni Sz., Varga Z., Őrfi L., Kéri Gy. Noszál B.: Acid-base profiling of imatinib (gleevec) and its fragments. J. Med. Chem., 2005, 48:249-255
  33. Szántai E., Szmola R., Sasváry-Székely M., Guttman A., Rónai Zs.: The polymorphic nature of the human dopamine D4 receptor gene: A comparative analysis of known variants and a novel 27 bp deletion in the promoter region. BMC Genetics, 2005, 6:39
  34. Szántai E., Rónai Zs., Szilágyi Á., Sasvári-Székely M., Guttman A.: Haplotyping by capillary electrophoresis. J. Chromatogr. „A”, 2005, 1079:41-49
  35. Szántai E., Király O., Nemoda Zs., Kereszturi E., Csapó Zs., Sasvári-Székely M., Gervai J., Rónai Zs.: Linkage analysis and molecular haplotyping of the dopamine D4receptor gene promoter region. Psychiatric Gen., 2005, 15:259-270
  36. Székelyhidi Zs., Pató J., Wáczek F., Bánhegyi P., Hegymegi-Barakonyi B., Erős D., Mészáros Gy., Hollósy F., Hafenbradl D., Obert S., Klebl B., Kéri Gy., Őrfi L.: Synthesis of selective SRPK-1 inhibitors: Novel tricyclic quinoxaline derivates. Bioorg. Med. Chem. Lett., 2005, 15:3241-3246
  37. Tejeda M., Gaál D., Csuka O., Kéri Gy.: Growth inhibitory effect of the somatostatin structural derivative (TT-232) on leukemia models. Anticancer Res., 2005, 25:325-330
  38. Tompa P., Szász Cs., Buday L.: Structural disorder throws new light on moonlighting. Trends Biochem. Sci., 2005, 30:484-489
  39. Varkondi E., Schafer E., Bökönyi Gy., Gyökeres T., Őrfi L.,Peták I., Pap Á., Szokoloczi O., Kéri Gy., Schwab R.: Comparison of elisa-based tyrosine kinase assays for screening EGFR inhibitors. J. Recep. Sign. Transd., 2005, 25:45-65
  40. Várnai P., Bondeva T., Tamás P., Tóth B., Buday L., Hunyady L., Balla T.: Selective cellular effects of overexpressed pleckstrin-homology domains that recognize Ptdlns (3,4,5)P3 suggest their interaction with protein binding partners. J. Cell Sci., 2005, 118:4879-4888

2004

  1. Bánhegyi G., Benedetti A., Fulceri R., Senesi S.: Cooperativity between 11β-hydroxysteroid dehydrogenase type 1 and hexose-6-phosphate dehydrogenase in the lumen of the endoplasmic reticulum. J. Biol. Chem., 2004, 279:27017-27021
  2. Batbayar B., Zelles T., Vér Á., Fehér E.: Plasticity of the different neuropeptide-containing nerve fibres in the tongue of the diabetic rat. J. Peripher. Nerv. Syst., 2004, 9:215-223
  3. Békési G., Rácz K., Hrabák A., Kakucs R., Várbíró S., Magyar Z., Fehér J., Dinya E., Pázmány T., Paku S., Székács B.: Systematic investigation of different steroid precursors with respect to their effect superoxide anion production by human neutrophil granulocytes. Horm. Metabol. Res., 2004, 36:155-163
  4. Blencke S., Zech B., Engkvist O., Greff Z., Őrfi L., Horváth Z., Kéri Gy., Ullrich A., Daub H.: Characterization of a conserved structural determinant contrtolling protein kinase sensitivity to selective inhibitors. Chem. Biol., 2004, 11:691-701
  5. Csala M., Staines A.G., Bánhegyi G., Mandl J., Coughtrie M.W.H., Burchell B.: Evidence for multiple glucoronide transporters in rat liver microsomes. Biochem. Pharmacol., 2004, 68:1353-1362
  6. Csermely P.: Strong links are important, but weak links stabilize them. TIBS, 2004, 29:331-334
  7. Dobos Zs., Lóránt T., Hollósy F., Hallgas B., Erdős D., Mészáros Gy., Kéri Gy., Idei M.: Determination of the basicity of Mannich ketones by capillary electrophoresis. J. Chromatogr. ”B” 2004, 799:179-183
  8. Erős D., Kéri Gy., Kövesdi I., Szántai-Kis Cs., Mészáros Gy., Őrfi L.: Comparison of predictive ability of water solubility QSPR models generated by MLR,PLS and ANN mehods. Medic. Chem., 2004, 4:167-177
  9. Erős D., Őrfi L., Kéri Gy.: Rational drug design and signal transduction therapy. Drug. Res., 2004. jan/febr, 27-30 www.b5srl.com
  10. Farkas A., Nardai G., Csermely P., Tompa P., Friedrich P.: DUK114, the Drosophila orthologue of bovine brain calpain Activatopr protein, is a molecular chaperone. Biochem. J., 2004, 382:165-170
  11. Fábián T.K., Tóth Zs., Fejérdy L., Kaán B, Csermely P., Fejérdy P.: Photo-acoustic stimulation increases the amount of 70 kDa heat shock protein (Hsp70) in human whole saliva. A pilot study. Int. J. Psychophys., 2004, 52:211-216
  12. Fejérdy L., ,Tóth Zs., Kaán B., Fábián T.K., Csermely Péter., Fejérdy P.: Lokális hő-és mechanikai stressz (masszázs) simuláció hatása az emberi kevert nyál molekuláris chaperon (Hsp70) koncentrációjára. Előzetes vizsgáltok. Fogorvosi Szemle, 2004, 5:204-210
  13. Fekete A., Vannay Á., Vér Á., Vásárhelyi B., Müller V., Ouyang N., Reusz Gy., Tulassay T., Szabó A.J.: Sex differences int he alterations of Na+, K+-ATPase following ischaemia reperfusion injury in the rat kidney. J. Physiol., 2004, 555:471-480
  14. Gujdár A., Sipeki Sz., Bander E., Buday L., Faragó A.: Protein kinase C modulates negatively the hepatocyte growth factor-induced migration, integrin expression and phosphatidylinositol 3-kinase activation. Cell. Sign., 2004, 16:505-513
  15. Hallgas B., Patonay T., Kiss-Szikszai A., Dobos Zs., Hollósy F., Erős D., Őrfi L., Kéri Gy., Idei M.: Comparison of measured and calculated lipophilicity of substituted aurones and related compounds. J. Chromatogr. „B” 2004, 801:229-235
  16. Helyes Zs., Szabó Á., Németh J., Jakab B., Pintér E., Bánvölgyi Á., Kereskai L., Kéri Gy., Szolcsányi J.: Antiinflammatory and analgesic effects of somatostatin released from capsaicin-sensitive sensory nerve terminals in a freund’s adjuvant-induced chronic arthitis model int the rat. Arthr. Rheum., 2004, 50:1677-1685
  17. Hofstaetter J.G., Saad F.A., Samuel R.E., Wunderlich L., Choi YH., Glimcher M.J.: Differential expression of VEGF isoforms and receptors in knee joint menisci under systemic hypoxia. Biochem. Biophys. Res. Commun., 2004, 324:667-672
  18. Hollósy F., Kéri Gy.: Plant-derived protein tyrosine kinase inhibitors as anticancer agents. Curr. Med. Chem. Anticancer Agents, 2004, 4:173-197
  19. Kabakov A.E., Budagova K.R., Malyutina Y.V., Latchman D.S., Csermely P.: Pharmacological attenuation of apoptosis in reoxygenated endothelial cells. Cell. Mol. Life Sci., 2004, 61:3076-3086
  20. Keszler G., Spasokoukotskaja T., Csapó Zs., Talianidis I., Eriksson S., Staub M., Sasvári-Székely M.: Activation of deoxycytidine kinase in lymphocytes is calcium dependent and involves a conformational change detectable by native immunostaining. Biochem. Pharmacol., 2004, 67:947-955
  21. Keszler G., Spasokoukotskaja T., Csapó Zs., Virga Sz., Staub M., Sasvári-Székely M.: Selective increase of dATP pools upon activation of deoxycytidine kinase in lymphocytes: implicationsin apoptosis. Nucleos. Nucleot. Nucl., 2004, 23:257-264
  22. Keszler G., Spasokoukotskaja T., Virga Sz., Sasvári-Székely M., Staub M.: Stimulation of deoxycytidine kinase results in prolonged maintenance of the enzyme activity. Nuleos. Nucleot. Nucl., 2004, 23:279-283
  23. Miyazaki A., Yokoi T., Tachibana Y., Enomoto R., Lee E., Bökönyi Gy., Kéri Gy., Tsuda Y., Okada Y.: Design and synthesis of novel type somatostatin analogs with antiproliferative activities on A431 tumor cells. Tetrahedron Lett., 2004, 45:6323-6327
  24. Őrfi L., Wáczek F., Pató J., Varga I., Hegymegi-Barakonyi B., Houghten R.A., Kéri Gy.: Improved, high yield synthesis of 3H-Quinazolin-4-ones, the key intermediates of recently developed drugs. Curr. Med. Chem., 2004, 11:763-771
  25. Özvegy-Laczka Csilla, Hegedűs T., Várady Gy., Ujhelly O., Schuetz J.D., Váradi A., Kéri Gy., Őrfi L., ,Német K., Sarkadi B.: High-affinity interaction on tyrosine kinase inhibitors with the ABCG2 multidrug transporter. Mol. Pharmacol., 2004, 65:1485-1495
  26. Rónai Zs., Guttman A., Keszler G., Sasvári-Székely M.: Capillary electrophoresis study on DNA-protein complex formation in the polymorphic 5’upstream region of the dopamine D4 receptor (DRD4) gene. Curr. Med. Chem., 2004, 11:1241-1253
  27. Rónai Zs., Szántai E., Szmola R., Nemoda Zs., Székely A., Gervai J., Guttman A., Sasvári-Székely M.: A novel A/G SNP int he -615th position of the dopamine D4 receptor promoter region as a source of misgenotyping of the-616 C/G SNP. Amer. J. Med. Gen. Part B, 2004, 126B:74-78
  28. Simon Á., Czajlik A., Perczel A., Kéri Gy., Nyikos L., Emri Zs., Kardos J.: Binding crevice for TT-232 in a homology model of type 1 somatostatin receptor. Biochem. Biophys. Res. Com., 2004, 316:1059-1064
  29. Somogyi J., Szalay J., Pándics T., Rosta K., Csermely P., Vér Á.: Új szteroidhormon-család: az endogén szívglikozidok és szerepük a szervezetben fiziológiás és patológiás körülmények között. Orvosi Hetilap, 2004, 6:259-266
  30. Sreedhar A.S., Nardai G., Csermely P.: Enhancement of complement-induced cell lysis: a novel mechanism for the anticancer effects of Hsp90 inhibitors. Immunol. Lett., 2004, 92:157-161
  31. Sreedhar A.S., Sőti Cs., Csermely P.: Inhibition of Hsp90: a new strategy for inhibiting protein kinases. BBA Prot. Struct. Mol. Enz., 2004, 1697:233-242
  32. Sreedhar A.S., Kalmár É., Csermely P., Shen Yu-Fei.: Hsp90 isoforms: functions, expression and clilnical importance. FEBS Lett., 2004, 562:11-15
  33. Sreedhar A.S., Csermely P.: Heat shock protein in the regulation of apoptosis: new strategies in tumor therapy. A comprehensive review. Pharmacol. Therap., 2004, 101:227-257
  34. Staub M.: A dezoxicitidin-kináz speciális szerepe a kemoterápiás nucleozidanalógok aktivitásában és a sejtosztódás gátlásában. Magyar Onkológia, 2004, 3:229-234
  35. Szabó A., Farkas Á., Vámos R., Bajor T., Hrabák A.: The inhibition of retinal inducible nitric oxide synthase overexpressioon and the attenuation of exprerimental uveitis by anti-inflammatory drugs in rats. Inflamm. Res., 2004, 53:262-267
  36. Szarka A., Horemans N., Bánhegyi G., Asard H.: Facilitated glucose and dehydroascorbate transport in plant mitochondria. Arch. Biochem. Biophys., 2004, 428:73-80
  37. Székely A., Rónai Zs., Nemoda Zs., Kolmann G., Gervai J., Sasvári-Székely M.: Human personality dimensions of persistence and harm avoidance associated with DRD4 and 5-HTTLPR polymorphisms. Amer. J. Med. Gen. Part B., 2004, 126B:106-110
  38. Szolcsányi J., Bölcskei K., Szabó Á., Pintér E., Pethő G., Elekes K., Börzsei R., Almási R., Szüts T., Kéri Gy., Helyes Zs.: Analgesic effect of TT-232, a heptapeptide somatostatin analogue, in acute pain models of the rat and the mouse and in streptozotocin-onduced diabetic mechanical allodyna. Eur. J. Pharmacol., 2004, 498:103-109
  39. Teich N., Le Maréchal C., Kukor Z., Caca K., Witzigmann H., Chen J-M., Tóth M., Mössner J., Keim V., Férec C., Sahin-Tóth M.: Interaction between trypsinogen isoforms in genetically determined pancreatitis: mutation E79K in cationic trypsin (PRSS1) causes increased transactivation of anionic trypsinogen (PRSS2). Hum. Mut., 2004, 23:22-31
  40. Tompla P., Csermely P.: The role of structural disorder int he function of RNA and protein chaperones. FASEB J., 2004 18:1169-1175
  41. Valent S., Tóth M.: Spectrophotometric analysis of the protective effect of ascorbate against spontaneous oxidation of tetrahydrobiopterin in aqueous solution: kinetic characteristics and potentiation by catalase of ascorbate action. Int. J. Biochem. & Cell Biol., 2004, 36:1266-1280
  42. Varsányi M., Szarka A., Papp E., Makai D., Nardai G., Fulceri R., Csermely P., Mandl J., Benedetti A., Bánhegyi G.: FAD transport and FAD-dependent protein thiol oxidation in rat liver microsomes. J. Biol. Chem., 2004, 279:3370-3374
  43. Vántus T., Vertommen D., Saelens X., Rykx A., De Kimpe L., Vancauwenbergh S., Mikhalap S., Waelkens E., Kéri Gy., Seufferlein T., Vandenabeele P., Rider M.H., Vandenheede J.R., Van Lint J.: Doxorubicin-induced activation of protein kinase D1 through caspase- mediated proteolytic cleavage: indentification of two cleavage sites by microsequencing. Cell. Sign., 2004, 16:703-709

2003

  1. Batbayar B., Somogyi J., Zelles T., Fehér E.: Immunohistochemical analysis of substance P containing nerve fibres and their contacts with mast cells in the diabetic rat’s tongue. Acta Biol. Hung., 2003, 54:275-283
  2. Bánhegyi G., Csala M., Nagy G., Sorrentino V., Fulceri R., Benedetti A.: Evidence for the transport of glutathione through ryanodine receptor. Biochem. J., 2003, 376:807-812
  3. Bánhegyi G., Csala M., Szarka A., Varsányi M., Benedetti A., Mandl J.: Role of ascorbate in oxidative protein folding. BioFactors, 2003, 17:37-46
  4. Chen J. M., Kukor Z., Maréchal C., Tóth M., Tsakiris L., Raguénes O., Férec C., Sahin-Tóth M.: Evolution of trypsinogen activation peptides. Mol. Biol. Evol., 2003, 20:1767-1777
  5. Csala M., Fulceri R., Mandl J., Benedetti A., Bánhegyi G.: Glutathione transport in the endo/sarcoplasmic reticulum. BioFactors, 2003, 17:27-35
  6. Csapó Zs., Keszler G., Sáfrány G., Spasokoukotskaja T., Talianidis I., Staub M., Sasvári-Székely M.: Activation of deoxycytidine kinase by gamma-irradiation and inactivation by hyperosmotic shock in human lymphocytes. Biochem. Pharmacol., 2003, 65:2031-2039
  7. Csermely P., Sőti Csa., Kalmár É., Papp E., Pató B., Vermes A., Sreedhar Amere A.: Molecular chaperones, evolution and medicine. J. Mol. Struct., 2003, 666-667:373-380
  8. Csermely P.: Recruiting the younger generation to science. A Network of Youth Excellence and communication strategies for high-school student researchers. (viewpoint) EMBO reports, 2003, 4:825-828
  9. Farkas Á., Vámos R., Bajor T., Müllner N., Lázár Á., Hrabák A.: Utilization of lacrimal urea assay in the monitoring of hemodialysis: conditions, limitations and lacrimal arginase characterization. Exp. Eye Res., 2003, 76:183-192
  10. Fábián T. K., Gáspár J., Fejérdy L., Kaán B., Bálint M., Csermely P., Fejérdy P.: Hsp70 is present in human saliva. Med. Sci. Monit., 2003, 9:BR62-65
  11. Gujdár A., Sipeki Sz., Bander E., Buday L., Faragó A.: Phorbol ester-induced migration of HepG2 cells is accompanied by intensive stress fibre formation, enhanced integrin expression and transient down-regulation of p21-activated kinase 1. Cell. Sign., 2003, 15:307-318
  12. Gyimesi-Forrás K., Szász K., Báthory G., Mészáros Gy., Gergely A.: Study ont he sorption properties of a1-acid glycoprotein (AGP)-based stationary phase modified by organic solvents. Chirality, 2003, 15:377-381
  13. Hargitai J., Lewis H., Boros I., Rácz T., Fiser A., Kurucz I., Benjamin I., Vigh L., Pénzes Z., Csermely P., Latchman D. S.: Bimoclomol, a heat shock protein co-inducer, acts by the prolonged activation of heat shock factor-1. Biochem. Biophys. Res. Commun., 2003, 307:689-695
  14. Horváth B., Hrabák A., Káldi K., Sándor P., Benyó Z.: Contribution of the heme oxygenase pathway to the maintenance of the hypothalamic blood flow during diminished nitric oxide synthesis. J. Cereb. Blood Flow Metabol., 2003, 23:653-657
  15. Idei M., Kiss É., Dobos Zs., Hallgas B., Mészáros Gy., Hollósy F., Kéri Gy.: Separation of anti-tumor peptides by capillary electrophoresis in organic solvent containing background electrolytes. Electrophoresis, 2003, 24:829-833
  16. Ishiwatari-Hayasaka H., Maruya M., Sreedhar Amere S., Nemoto K. T., Csermely P., Yahara I.: Interaction of neuropeptide Y and Hsp90 through a novel peptide binding region. Biochemistry, 2003, 42:12972-12980
  17. Jermendy Gy., Csermely P.: A benfotioamin szerepe a diabetes mellitus idült szövődményeinek patomechanizmusában és kezelésében: Experimentális adatok és klinikai megfigyelések. Magy. Belorv. Arch., 2003, 56:131-136
  18. Kalmár B., Greensmith L., Malcangio M., McMahon S.B., Csermely P., Burnstocia G.: The effect of treatment with BRX-200, a co-inducer of heat shock proteins, on sensory fibers of the rat following peropheral nerve injury. Exp. Neurol., 2003, 184:636-647
  19. Keszler G., Szikla K., Kazimierczuk Z., Spasokoukotskaja T., Sasvári-Székely M., Staub M.: Selective activation of deoxycytidine kinase by thymidine-5’-thiosulphate and release by deoxycytidine in human lymphocytes. Biochem. Pharmacol., 2003, 65:563-571
  20. Kéri Gy., Rácz G., Magyar K., Őrfi L., Horváth A., Schwab R., Hegymegi B.B., Szende B.: Pro-apoptotic and anti-apoptotic molecules affecting pathways of signal transduction. Ann. N. Y. Acad. Sci., 2003, 1010:109-112
  21. Kiss A.J., Botos E., Turi Á., Müllner N., Hollósi P., Kovalszky I.: Ocadaic acid treatment alters the intracellular localization of caveolin-1 and caveolin-2 in HepG2 cells. Acta Biol. Szegediensis, 2003, 47:11-17
  22. Kukor Z., Tóth M., Sahin-Tóth M.: Human anionic trypsinogen. Properties of autocatalytic activation and degradation and implications in pancreatic diseases. Eur. J. Biochem., 2003, 270:2047-2058
  23. Lakatos K., Nemoda Zs., Birkas E., Rónai Zs., Kovács E., Ney K., Tóth I., Sasvári-Székely M., Gervai J.: Association of D4 dopamine receptor gene and serotonin transporter promoter polymorphisms with infants’ response to novelty. Mol. Psychiatry, 2003, 8:90-97
  24. Leuzzi R., Bánhegyi G., Kardon T., Marcolongo P., Capecchi P. L., Burger H. J., Benedetti A., Fulceri R.: Inhibition of microsomal glucose-6-phosphate transport in human neutrophils results in apoptosis: a potential explanation for neutrophil dysfunction in glycogen storage disease type 1b. Blood, 2003, 101:2381-2387
  25. Mandl J., Medve L., Temesi A., Vizi E. Sz.: A biomedicinális kutatások etikai szabályozása Magyarországon. Orv. Hetilap, 2003, 144 évf. 2. sz. 73-76
  26. Mandl J., Bánhegyi G.: Role of glutathione in the regulation of liver metabolism. BioFactors 2003, 17:21-26
  27. Mansson E., Flordal E., Liliemark J., Spasokoukotskaja T., Elford H., Lagercrantz S., Eriksson S., Albertioni F.: Down-regulation of deoxycytidine kinase in human leukemic cell lines resistant to cladribine and clofarabine and increased ribonucleotide reductase activity contributes to fludarabine resistance. Biochem. Pharmacol., 2003, 65:237-247
  28. Nardai G., Korcsmáros T., Papp E., Csermely P.: Reduction of the endoplasmic reticulum accompanies the oxidative demage of diabetes mellitus. BioFactors, 2003, 17:259-267
  29. Papp E., Nardai G., Sőti Cs., Csermely P.: Molecular chaperones, stress proteins and redox homeostasis. BioFactors, 2003, 17:249-257
  30. Rónai Zs., Sasvári-Székely M., Guttman A.: Miniaturized SNP Detection: Quasi-Solid-Phase RFLP Analysis. BioTechniques, 2003, 34:1172-1173
  31. Rónai Zs., Wang Y., Khandurina J., Budworth P., Sasvári-Székely M., Wang X., Guttman A.: Transcription factor binding study by capillary zone electrophoretic mobility shift assay. Electrophoresis, 2003, 24:96-100
  32. Rosenhangen M. C., Sőti Cs., Schmidt U., Wochnik G. M., Hartl F. U, Holsboer F., Young J. C., Rein T.: The heat shock protein 90-Targeting drug cisplatin selectively inhibits steroid receptor activation. Mol. Endocrinol., 2003, 17:1991-2001
  33. Rykx A., De Kimpe L., Mikhalap S., Vántus T., Seufferlein T., Vandenheede J.R., Van Lint J.: Protein kinase D: a family affair. FEBS Lett., 2003, 546:81-86
  34. Sasvári-Székely M.: A Humán genom projekt. LAM, 2003, 13:102-109
  35. Scheiber D., Barta Csa., Halász Z., Sallai Á., Rácz K., Ságodi L., Fekete Gy., Hiort P., Sólyom J.: Mutation analysis of Hungarian patients with androgen insensitivity syndrome. J. Pediatr. Endocrinol. Metabol., 2003, 16:367-373
  36. Shi L., Khandurina J., Rónai Zs., Li B. Y., Kwan W. K., Wang X., Guttman A.: Micropreparative capillary gel electrophoresis of DNA: Rapid expressed sequence tag library construction. Electrophoresis, 2003, 24:86-92
  37. Sőti Cs., Csermely P.: Aging and molecular chaperones (mini-review) Exp. Gerontol., 2003, 38:1037-1040
  38. Sőti Cs., Sreedhart A. S., Csermely P.: Apoptosis, necrosis and cellular senescence: chaperone occupancy as a potential switch. (Minireview) Aging Cell, 2003, 2:39-45
  39. Sőti Cs., Vermes Á., Timothy A., Haystead J., Csermely P.: Comparative analysis of the ATP-binding sites of Hsp90 by nucleotide affinity cleavage: a distinct nucleotide specificity of the C-terminal ATP-binding site. Eur. J. Biochem., 2003, 270:2421-2428
  40. Sőti Cs., Nardai G., Csermely P.: Stresszfehérjék az orvostudományban. Orv. Hetil., 2003, 144 évf., 13 sz. 605-611
  41. Sreedhar S. A., Mihály K., Pató B., Schnaider T., Steták A., Kis-Petik K., Fidy J., Simonics T., Maráz A., Csermely P.: Hsp90 inhibition accelerates cell lysis. Anti-Hsp90 ribozyme reveals a complex mechanism of Hasp90 inhibitors involving both superoxide and Hsp90-dependent events. J. Biol. Chem., 2003, 278:35231-35240
  42. Szántai-Kis Cs., Kövesdi I., Kéri Gy., Őrfi L.: Validation subset selections for extrapolation oriented QSPAR models. Mol. Div., 2003, 7:37-43
  43. Szende B., Horváth A., Bökönyi Gy., Kéri Gy.: Effect of a novel somatostatin analogue combined with cytotoxic drugs on human tumour xenografts and metastasis of B 16 melanoma. Br. J. Cancer, 2003, 88:132-136
  44. Szende B., Kéri Gy.: TT-32: a somatostatin structural derivative as a potent antitumor drug candidate. Anti-CancerDrugs, 2003, 14:585-588
  45. Szepessy E., Nagy G., Jenei Zs., Serfőző Z., Csuka I., James J., Bánfalvi G.: Multiple subphases of DNA repair and poly (ADP-ribose) synthesis in Chinese hamster ovary (CHO-K1) cells. Eur. J. Cell Biol., 2003, 82:201-207
  46. Tamás P., Solti Z., Bauer P., Illés A., Sipeki Sz., Bauer A., Faragó A., Downward J., Buday L.: Mechanism of epidermal growth factor regulation of Vav2, a guanine nucleotide exchange factor for rac. J. Biol. Chem., 2003, 278:5163-5171
  47. Tejeda M., Gaal D., Barna K., Csuka O., Kéri Gy.: The antitumor activity of the somatostatin structural derivate (TT-232) on different human tumor xenografts. Anticancer Res., 2003, 23:4061-4066
  48. Török Zs., Tsvetkova N. M., Balogh G., Horváth I., Nagy E., Pénzes Z., Hargitai J., Bensaude O., Csermely P., Crowe J. H., Maresca B., Vigh L.: Heat shock protein coinducers with no effect on protein denaturation specifically modulate the membrane lipid phase. Proc. Natl. Acad. Sci., 2003, 100:3131-3136

2002

  1. Barta Cs., Sasvári-Székely M., Dévai A., Kovács E., Staub M., Enyedi P.: Analysis of mutations int he plasma cholinesterase gene of patients with a history of prolonged neuromuscular block during anesthesia. Mol. Gen. Metabol., 2002, 22:779-782
  2. Boór K., Rónai Zs., Nemoda Zs., Gaszner P., Székely-Sasvári M.: Noninvasive genotyping of dopamine receptor D4 (DRD4) using nanograms of DNA from substance-dependent patients. Current Med. Chem., 2002, 9:793-797
  3. Boór K., Rónai Zs., Sasvári-Székely M., Gasztner P., Kalász H.: The use of planar electrophoresis for detection of single-nucleotide polymorphism. IPC-J. Plan. Chromatogr., 2002, 15:101-105
  4. Buday L., Wunderlich L., Tamás P.: The Nck family of adapter proteins: Regulators of actin cytoskeleton. Cell. Sign., 2002, 14:723-731
  5. Dénes L., Jednákovits A., Hargitai J., Pénzes Z., Balla A., Tálosi L., Krajcsi P., Csermely P.: Pharmacologically activated migration of aortic endothelial cells is mediated through p38 SAPK. Br. J. Pharmacol., 2002, 136:597-603
  6. Erős D., Kövesdi I., Őrfi L., Takács-Novák K., Acsády Gy., Kéri Gy.: Reliability of logP prediction based on calculated molecular descriptors: A critical review. Curr. Med. Chem., 2002, 9:1241-1253
  7. Fenyő M., Mandl J., Falus A.: Opposite effect of linearly polarized light on biosynthesis of interleukin-6 in a human B lymphoid cell line and peripherial human monocytes. Cell Biol. Internat., 2002, 26:265-269
  8. Guttman A., Rónai Zs., Barta Cs., Hou Y.M., Székely-Sasvári M., Wang X., Briggs P.S.: Membrane-mediated ultrafast restriction and subsequent rapid gel microchip electrophoresis of DNA. Electrophoresis, 2002, 23:1524-1530
  9. Guttman A., Csapó Zs., Robbins D.: Rapid two-dimensional analysis of proteins by ultra-thin layer gel electrophoresis. Proteomics, 2002, 2:469-474
  10. Hegedűs T., Őrfi L., Seprődi A., Váradi A., Sarkadi B., Kéri Gy.: Interaction of tyrosine kinase inhibitors with the human multidrug transporter proteins, MDR1 and MRP1. Biochim. Biophys. Acta, 2002, 1587:318-325
  11. Hollósy F., Sprődi J., Őrfi L., Dániel E., Kéri Gy., Idei M.: Evaluation of lipophilicity and antitumour activity of parallel carboxamide libraries. J. Chromatogr. “B”, 2002, 780:355-363
  12. Hollósy F., Lóránd T., Őrfi L., Erős D., Kéri Gy., Idei M.: Evaluation of hydrophobicity and antitumor activity of a molecule library of mannich ketones of cycloalkanones. J. Liq. Chrom. Rel. Technol., 2002, 25:1129-1143
  13. Hollósy F.: Effects of ultraviolet radiation on plant cells. Micron, 2002, 33:179-197
  14. Hollósy F., Lóránd T., Őrfi L., Erős D., Kéri Gy., Idei M.: Relationship between lipophilicity and antitumor activity of molecule library of Mannich ketones determined by high-performance liquid chromatography, clogP calculation and cytotoxicity test. J. Chromatogr. “B”, 2002, 768:361-368
  15. Horváth A., Olive C., Wong A., Clair T., Yarwood P., Good M., Tóth I.: Lipoamino acid-based adjuvant carrier system: enhanced immuno-genicity of group A streptococcal peptide epitopes. J. Med. Chem., 2002, 45:1387-1390
  16. Horváth A., Olive C., Wong A., Clair T., Yarwood P., Tóth I.: A lipophilic adjuvant carrier system for antigenic peptides. Lett. Pept. Sci., 2002, 8:285-288
  17. Kalmár B., Burnstock G., Vrbová G., Urbanics R., Csermely P., Greensmith L.: Upregulation of heat shock proteins rescues motoneurones from axotomy-induced cell death in neonatal rats. Exp. Neurol., 2002, 176:87-97
  18. Kardon T., Mile V., Bánhegyi G., Csala M., Burchell B., Mandl J., Braun L.: Ethanol-dependent induction of bilirubin UDP-glucuronosyl-transferase in rat liver is mediated by Kupffer cells. Life Sci., 2002, 70:1205-1212
  19. Kiss A.L., Turi A., Müllner N., Kántor O., Botos E.: Caveolae and caveolin isoforms in rat peritoneal macrophag. Micron, 2002, 33:75-93
  20. Kovács M., Seprődi A., Koppan M., Horváth E., Vincze B., Teplán I., Flerkó B.: Lamprey gonadotropin hormone-releasing hormone-III has no selective follicle-stimulating hormone-releasing effect in rats. J. Neuroendocrinol., 2002, 14:647-655
  21. Kukor Z., Mayerle J., Krüger B., Tóth M., Steed P.M., Halangk W., Lerch M.M., Sahin-Tóth M.: Presence of cathepsin B in the human pancreatic secretory pathway and its role in trypsinogen activation during hereditary pancreatitis. J. Biol. Chem., 2002, 277:21389-21396
  22. Kukor Z., Tóth M., Pál G., Sahin-Tóth M.: Human cationic trypsinogen. Arg117 is the reactive site of an inhibitory surface loop that controls spontaneous zymogen activation. J. Biol. Chem., 2002, 277:6111-6117
  23. Lakatos K., Nemoda Zs., Tóth I., Rónai Zs., Ney K., Sasvári-Székely M., Gervai J.: Futher evidence for the role of the dopamine D4 receptor (DRD4) gene in attachment disorganization: interaction of the exon III 48-bp repeat and the-521 C/Tpromoter polymorphisms. Molec. Psychiatry, 2002, 7:27-31
  24. Van Lint J., Rykx A., Vántus T., Vandenheede J.R.: Molecules in focus. Getting to know protein kinase D. Int. J. Biochem. Cell Biol., 2002, 34:577-581
  25. Van Lint J., Ryks A., Maeda Y., Vántus T., Sturany S., Malhotra V., Vandenheede J.R., Seufferlein T.: Protein kinase D: an intracellular traffic regulator on the move. Trends Cell Biol., 2002, 12:193-200
  26. Müllner N., Lázár Á., Hrabák A.: Enhanced utilization and altered metabolism of arginine in inflammatory macrophages caused by raides nitric oxide synthesis. Int. J. Biochem. Cell Biol., 2002, 34:1080-1090
  27. Nardai G., Csermely P., Sőti Cs.: Chaperone function and chaperone overload in the aged. A preliminary analysis. Exp. Geront., 2002, 37:1257-1262
  28. Nemoda Zs., Tárnok Zs., Gárdos J., Sasvári-Székely M.: A figyelemhiányos hiperaktivitási zavar genetikai vizsgálatának fő irányvonalai. Orvosképzés, 2002, 77. évf. 4. szám, 257-268
  29. Patócs A., Tóth M., Barta Cs., Székely-Sasvári M., Varga I., Szűcs N., Jakab Cs., Gláz E., Rácz K.: Hormonal evaluation and mutation screening for steroid 2l-hydroxylase deficiency in patients with unilateral and bilateral adrenal incidentalomas. Eu. J. Endocrinol., 2002, 147:349-355
  30. Pintér E., Helyes Zs., Németh J., Pórszász R., Pethő G.: Thán M., Kéri Gy., Horváth A., Jakab B., Szolcsányi J.: Pharmacological characterisation of the somatostatin analogue TT-232: effect on neurogenic and non-neurogenic inflammation and neuropathic hyperalgesia. N-S Arch. Pharmacol., 2002, 366:142-150
  31. Rónai Zs., Guttman A., Nemoda Zs., Gervai J., Székely-Sasvári M.: Direct haplotype detection of adjancent polymorphic sites in the regulatory region of the dopamine D4 receptor (DRD4) gene. Electrophoresis, 2002, 23:1512-1516
  32. Rónai Zs., Sasvári-Székely M., Chován T., Guttman A.: Elektroforetikus mikrochipek alkalmazása gyors DNS-analízisre. Biokémia, 2002, 26.évf. 2:26-33
  33. Rónai Zs., Székely-Sasvári M., Guttman A.: Miniaturized SNP detection: quasi-solid-phase restriction-fragmen-length-polymorphism analysis. Technical Tips Online, 2002, 1:TO2678
  34. Shandrick S., Rónai Zs., Guttman A.: Rapid microwell polymerase chain reaction with subsequent ultrathin-layer gel electrophoresis of DNA. Electrophoresis, 2002, 23:591-595
  35. Sipeki Sz., Bander E., Ways Kirsk D., Faragó A.: Activation of Erk1/Erk2 and transiently increased p53 levels together may account for p21 exspression associated with phorbol ester- induced transient growth inhibition in HepG2 cells. Cell Sign., 2002, 14:115-121
  36. Sőti Cs., Csermely P.: Chaperones and aging: role in neurodegeneration and in other civilizational diseases. Neurochem. Internat., 2002, 41:383-389
  37. Sőti Cs., Csermely P.: Chaperones come of age. Cell Stress Chaperones, 2002, 7:186-190
  38. Sőti Cs., Rácz A., Csermely P.: A nucleotide-dependent molecular switch controls ATP binding at the C-terminal domain of Hsp90. N-terminal nucleotidebinding unmasks a C-terminal binding pocket. J. Biol. Chem., 2002, 277:7066-7075
  39. Szarka A., Stadler K., Jenei V., Margittai É., Csala M., Jakus J., Mandl J., Bánhegyi G.: Ascorbyl free radical and dehydroascorbate formation in rat liver endoplasmic reticulum. J. Bioenerg. Biomembr., 2002, 34:317-323
  40. Szántó S., Csermely P., Kovács I., Csongor J., Illés Á., Bakó Gy., Szegedi Gy., Sipka S.: Inhibition of arachidonic acid release from human peripherial mononuclear cells by heat shock treatment and geldanamycin. Immunol. Lett., 2002, 83:181-185
  41. Szende B., Okada Y., Tsuda Y., Horváth A., Bökönyi Gy., Okamoto S., Wanaka K., Kéri Gy.: A novel plasmin-inhibitor inhibits the growth of human tumor xenografts and decreases metastatis number. In vivo, 2002, 16:281-286
  42. Tóth M., Kukor Z., Valent S.: Chemical stabilization of tetrahydrobiopterin by L-ascorbic acid:contribution to placental endothelial nitric oxide synthase activity. Mol. Hum. Reptod., 2002, 8:271-280
  43. Tóth M.: A tetrahidrobiopterin szerepe a humán placenta nitrogén-monoxid-szintáz aktivitásának szabályozásában normális és praeeclampsiás terhességekben. Orvosi Hetilap, 2002, 143 évf. 8391-398

2001

  1. Barta Cs., Rónai Zs., Nemoda Zs., Székely A., Kovács E., Sasvári-Székely M., Guttman A.: Analysis of dopamine D4 receptor gene polymorphism using microchip eletrophoresis. J. Chromatogr. “A”, 2001, 924:285-290
  2. Barta Cs., Rónai Zs., Sasavári-Székely M., Guttman A.: Rapid single nucleotide polymorphism analysis by primer extension and capillary electrophoresis using polyvinyl pyrrolidone matrix. Electrophoresis, 2001, 22:779-782
  3. Bánhegyi G., Mandl J.: The hepatic glycogenoreticular system. Pathol. Oncol. Research, 2001, 7:107-110
  4. Békési G., Kakucs R., Sándor J., Sárváry E., Kocsis I., Spintz D., Várbíró Sz., Magyar Z., Hrabák A., Fehér J., Székács B.: Plasma concentration of myeloperoxidase enzyme in pre- and post-climacterial people: related superoxide anion generation. Exp. Geront., 2001, 37:137-148
  5. Braun L., Kardon T., Reist-Porszasz Zs., Bánhegyi G., Mandl J.: The regulation of the induction of vascular endothelial gowth factor at the onset of diabetes in spontane ously diabetic rats. Life Sci., 2001, 69:2533-2542
  6. Cavarra E., Lucattelli M., Gambelli F., Bartalesi B., Fineschi S., Szarka A., Giannerini F., Martorana P.A., Lungarella G.: Human SLPI inactivation after cigarette smoke exposure in a new in vivo model of pulmonary oxidative stress. Am. J. Physiol. Lung Cell. Mol. Physiol., 2001, 281:L412-L417
  7. Csala M., Szarka A., Margittai É., Mile V., Kardon T., Braun L., Mandl J., Bánhegyi G.: Role of vitamin E in ascorbate-dependent protein thiol oxidation in rat liver endoplasmic reticulum. Arch. Biochem. Biophys., 2001, 388:55-59
  8. Csala M., Fulceri R., Mandl J., Benedetti A., Bánhegyi G.: Ryanodine receptor channel-dependent glutathione transport in the sarcoplasmic reticulum of skeletal muscle. Biochem. Bipohys. Res. Comm., 2001, 287:696-700
  9. Csapó Zs., Sasvári-Székely M., Spasokoukotskaja T., Talianidis I., Eriksson S., Staub M.: Activation of deoxycytidine kinase by inhibition of DNA  synthesis in human lymphocytes. Biochem. Pharmacol., 2001, 61:191-197
  10. Csapó Zs., Sasvári-Székely M., Spasokoukotskaja T., Staub M.: Modulation of human deoxycytidine kinase activity as a response to cellular stress induced by NaF. Acta Biochim. Polonica, 2001, 48:251-256
  11. Csermely P.: A nonconventional role of molecular chaperones: Involvement in the cytoarchitecture. News Physiol. Sci., 2001, 15:123-126
  12. Csermely P.: Chaperone overload is a possible contributor to „civilization diseases”. TRENDS in Genetics, 2001, 17:701-704
  13. Csermely P.: Water and cellular folding processes. Cell Mol. Biol., 2001, 47:791-800
  14. Darvas F., Dorman Gy., Urge L., Szabó I., Rónai Zs., Sasvári-Székely M.: Combintorial chemistry. Facing the challenge of chemical genomics. Pure Appl. Chem., 2001, 73:1487-1498
  15. Demeter A., Abonyi M., Look K., Keszler G., Staub M., Weber G.: Differences in thermostability of thymidine kinase isoenzymes in normal ovary and ovarian carcinoma. Anticancer Res., 2001, 21:353-358
  16. Hollósy F., Idei M., Csorba G., Szabó E., Bökönyi Gy., Seprődi A., Mészáros Gy., Szende B., Kéri Gy.: Activation of caspase-3 protease during the process of ursolic acid and its derivative-inducesd apoptosis. Anticancer Res., 2001, 21:3485-3492
  17. Hrabák A., Vercruysse V., Kahán I.L., Vray B.: Indomethacin prevents the induction of inducible nitric oxide synthase in murine peritoneal macrophages and decreases their nitric oxide production. Life Sci., 2001, 68:1923-1930
  18. Idei M., Kiss É., Hollósy F., Boróka T.,  Őrfi L., Seprődi J., Mészáros Gy., Kéri Gy.: Calculation of phase residence times in micellar electrokinetic chromatography. J. Liq. Chrom. Rel. Technol., 2001, 24:303-315
  19. Jermendy Gy., Csermely P.: Tiazolidindionok- az oralis antidiabeticumok új hatástani csoportja. Orvosi Hetilap, 2001, 29:1547-15154
  20. Kiss G., Somogyi J., Csermely P., Szelényi J., Vér Á.: Streptozotocin-induced diabetes alters the oligomerization pattern of acetylcholinesterase in rat skeletal muscle. Diabetologia, 2001, 44:220-223
  21. Kocsis I., Vásárhelyi B., Héninger E., Vér Á., Tulassay T.: Expression and activity of the Ca2+-ATPase enzyme in human neonatal erythrocytes. Biol. Neonate, 2001, 80:215-218
  22. Koncz G., Tóth G.T., Bökönyi Gy., Kéri Gy., Pecht I., Medgyesi F., Gergely J., Sármay G.: Co-clustering of Fcγ and B cell receptors induces dephosphorylation of the Grb2-associated binder 1 docking protein. Eur. J. Biochem., 2001, 268:3898-390
  23. Leuzzi R., Fulceri R., Marcolongo P., Bánhegyi G., Zammarchi E., Stafford K., Burchell A., Benedetti A.: Glucose 6-phosphate transport in fibroblast microsomes from glycogen storage disease type 1b patients: evidence for multiple glucose 6-phosphate transport systems. Biochem. J., 2001, 357:557-562
  24. Lofti K., Mansson E., Chandra J.,Wang Y., Xu D., Knaust E., Spasokoukotskaja T., Liliemark E., Eriksson S., Albertioni F.: Pharmacological basis for cladribine resistance in a human acute T lymphoblastic leukaemia cell line selected for resistance to etoposide. Br. J. Haematol., 2001, 113:339-346
  25. Nardai G., Braun L., Csala M., Mile V., Csermely P., Benedetti A., Mandl J., Bánhegyi G.: Protein disulfide isomerase- and protein thiol-depentent dehydroascorbate reduction and ascorbate accumulation in the lumen of the endoplasmic reticulum. J. Biol. Chem., 2001, 276:8825-8828
  26. Nemoda Zs., Rónai Zs., Székely A., Kovács E., Shandrich S., Guttman A., Sasvári-Székely M.: High-throughput genotyping repeat polymorsphism in the regulatory region of serotomin trasporter gene by gel microchip electrophoresis. Electrophoresis, 2001, 22:4008-4011
  27. Preiser J.C., Zhang H., Vray B., Hrabák A., Vincent J.L.: Time course of inducible nitric oxide synthase activity following endotoxin administration in dogs. Nitric Oxide: Biol.Chem., 2001, 5:208-211
  28. Rónai Zs., Székely A., Nemoda Zs., Lakatos K., Gervai J., Staub M., Sasvári-Székely M.: Association between novelty seeking and the-521 C/T polymorphism in the promoter region of the DRD4 gene. Mol. Psychiatry, 2001, 6:35-38
  29. Rónai Zs., Barta Cs., Sasvári-Székely M., Guttman A.: DNA analysis on electrophoretic microchips: Effect of operational variables. Electrophoresis, 2001, 22:294-299
  30. Rónai Zs., Barta Cs., Guttman A., Lakatos K., Gervai J., Staub M., Sasvári-Székely M.: Genotyping the -521C/T functional polymorphism in the promoter region of dopamine D4 receptor (DRD4) gene. Electrophoresis, 2001, 22:1102-1105
  31. Sahin-Tóth M., Tóth M.: A tripszinogén gén mutációinak jelentősége az örökletes hasnyálmirigy-gyulladás kóroktanában. Orvosi Hetilap, 2001, 12:603-606
  32. Schwab R.E., Froidevaux S., Paku S., Tejeda M., Szende B., Pap Á., Beglinger C., Eberle A.N., Kéri Gy.: Antiproliferative efficacy of the somatostatin analogue TT-232 in human melanoma cells and tumours. Anticancer Res., 2001, 21:72-76
  33. Somogyi J., Kiss G., Pentek E., Csermely P., Vér Á.: Diabetes mellitus mint általános membránbetegség és ennek következményei. Orvosi Hetilap, 2001, 33:178l-1788
  34. Tamás P., Solti Z., Buday L.: Membrane-targeting is critical for the phosphorylation of Vav2 by activated EGF receptor. Cell. Sign., 2001, 13:475-481
  35. Steták A., Lankenau A., Vántus T., Csermely P., Ullrich A., Kéri Gy.: The antitumor somatostatin analogue TT-232 induces cell cycle arrest through PKCδ and c-Src. Biochem. Biophys. Res. Comm., 2001, 285:483-488
  36. Steták A., Csermely P., Ullrich A., Kéri Gy.: Physical and functional interactions between protein tyrosine phosphatase α, PI 3-Kinase, and PKCδ. Biochem. Biophys. Res. Comm., 2001, 288:564-572
  37. Szende B., Bökönyi Gy. Bocsi J., Kéri Gy., Tímár F., Magyar K.: Anti-apoptotic and apoptotic action of (-)-deprenyl and its metabolites. J. Neural Transm., 2001, 108:25-33
  38. Tamás P., Solti Z., Buday L.: Membrane-targeting c ritical for the phosphorylation of Vav2 by activated EGF receptor. Cell Sign., 2001, 13:475-481
  39. Theodoropoulou M., Barta Cs., Szőke M., Guttman A., Staub M., Niederland T., Sólyom J., Fekete Gy., Sasvári-Székely M.: Prenatal diagnosis of steroid 21-hydroxylase deficiency by allele-specific amplification. Fetal Diagn. Ther., 2001, 16:237-240
  40. Turi Á., Kiss A.L., Müllner N.: Estrogen downregulates the number of caveolae and the lev caveolin in uterine smooth muscle. Cell Biol. Int., 2001, 25:785-794
  41. Vántus T., Kéri Gy., Krivickiene Z., Valius M., Steták A., Keppens S., Csermely P., Bauer P.I., Bökönyi I., Declercq W., Vandenabeele P., Merlevede W., Vandenheede J.R.: The somatostatin analogue TT-232 induces apoptosis in A431 cells sustained activation of stress-activated kinases and inhibition of signalling to extracellular signal-regulated kinase. Cell. Sign., 2001, 13:717-725

2000

  1. Bánfalvi G., Littlefield N., Hass B.,, Mikhailvva M., Csuka I., Szepessy E., Wu Chou M.: Effect of cadmium ont he relationship between replicative and repair DNA synthesis in synchronized CHO cells. Eur. J. Biochem., 2000, 267:6580-6585
  2. Bökönyi Gy., Horváth A., Őrfi L., Edit Z.Szabó, Houghten R.A., Ostresh J.M., Idei M., Hollósy F., Szende B., Teplán I, Kéri Gy.: Screening of peptidomimetic libraries for antitumor activity. Peptides, 2000.791-792
  3. Csala M., Bánhegyi G., Braun L., Szirmai R., Burchell A., Burchell B., Benedetti A., Mandl J.: β-Glucuronidase latency in isolated murine hepatocytes. Biochem. Pharmacol., 2000, 59:801-805
  4. Csala M., Mile V., Benedetti A., Mandl J., Bánhegyi G.: Ascorbate oxidation is a prerequisite for its transport into rat liver microsomal vesicles. Biochem. J., 2000, 349:413-415
  5. Csala M., Braun L., Coffey M.J., Puskás F., Kardon T., Nagy G., Conley A.A., Burchell B., Mandl J.: A bilirubin UDP-glukuroniltranszferáz indukciója diabéteszes, acetonnal kezelt és éhező patkányokban. Biokémia, 2000, 24:7-12
  6. Csapó Zs., Gerstner A., Sasvári-Székely M., Guttman A.: Automated ultra-thin-layer SDS gel electrophoresis of proteins using noncovalent fluorescent labeling. Anal. Chem., 2000, 72:2519-2525
  7. Csermely P.: Crowding Stress. Encyclopedia of Stress, 2000, 1:601-603
  8. Csermely P., Halász G., Jeney G., Máthé J., Mikló L., Solymári D., Szekeres Á., Tamás G.: Research training between 14 and 18 in Hungary. Biochem. Ed., 2000, 28:132-133
  9. Csermely P., Sőti Cs., Schnaider T., Steták A.: Az extracelluláris jel továbbítása a sejtmagba. Orvosképzés, 2000, 75:32-40
  10. DeFranco D.B., Csermely P.: Steroid receptor and molecular chaperone encounters in the nucleus. Science’s STKE, 2000, 42:1-5
  11. Fulceri R., Kardon T., Bánhegyi G., Pralong W.F., Gamberucci A., Marcolongo P., Benedetti A.: Glucose-6-phosphatase in the insulin secreting cell line INS-1, Biochem. Biophys. Res. Comm., 2000, 275:103-107
  12. Garami M., Ferenczi A., Kiss E., Sasvári-Székely M., Barta Cs., Sólyom J., Fekete Gy.: Magyarországi 21-hidroxiláz defektusos gyermekek genotipusának meghatározása. Gyermekgyógyászat, 2000, 51. év.4. szám 352-359
  13. Gerstner A., Sasvári-Székely M., Kalász H., Guttman A.: Sequencing difficult DNA templates using membrane-mediated loading with hot sample application. Biotechniques, 2000, 28:628-630
  14. Gerstner A., Csapó Zs., Sasvári-Székely M., Guttman A.: Ultrathin-layer sodium dodecyl sulfate gel electrophoresis of proteins: Effects of gel composition and temperature on the separation of sodium dodecyl sulfate-protein complexes. Electrophoresis, 2000, 21:834-840
  15. Guttman A., Lengyel T., Szőke M., Sasvári-Székely M.: Ultra-thin-layer agarose gel electrophoresis: II. Separation of DNA fragments on composite agarose-linear polymer matrices. J. Chromatogr. A, 2000, 871:289-298
  16. Guttman A., Rónai Zs., Csapó Zs., Gerstner A., Sasvári-Székely M.: Rapid analysis of covalently and non-covalently fluorophore-labeled proteins using ultra-thin-layer sodium dodecylsulpfate gel electrophoresis. J. Chromatogr. A, 2000, 894:329-335
  17. Guttman A., Rónai Zs.: Ultrathin-layer gel electrophoresis of biopolymers. Electrophoresis, 2000, 21:3952-3964
  18. Helyes Zs., Thán M., Oroszi G., Pintér E., Németh J., Kéri Gy.,Szolcsányi J.: Anti-nociceptive effect induced by somatostatin released from sensory nerve terminals and by synthetic somatostatin analogues in the rat. Neurosci. Lett., 2000, 278:185-188
  19. Hollósy F., Mészáros Gy., Bökönyi Gy., Idei M., Seprődi A., Szende B., Kéri Gy.: Cytostatic, cytotoxic and protein tyrosine kinase inhibitory activity of ursolic acid A431 human tumor cells. Anticancer Res., 2000, 20:4563-4570
  20. Hrabák A., Körner A., Császár A.: A citokinek és a nitrogén-monoxid részvétele az 1-es típusú diabetes mellitus kialakulásához vezető autoimmun folyamatokban. Diabetologia Hungarica, 2000, 8:87-97
  21. Kardon T., Coffey M.J., Bánhegyi G., Conley A.A., Burchell B., Mandl J., Braun L.: Transcriptional induction of bilirubin UDP-glucuronosyltransferase by ethanol in rat liver Alcohol, 2000, 21:251-257
  22. Keszler G., Csapó Zs., Spasokokoutskaja T., Sasvári-Székely M., Virga S., Demeter A., Eriksson S., Staub M.: Hyperthermy increase the phosphorylation of deoxycytidine in the membrane phospholipid precursors and decrease its incorporation into DNA. Adv. Exp. Med. Biol., 2000, 486:333-337
  23. Kiss A.L., Túri Á., Müllner N., Tímár J.: Caveolin isoforms in resident and elicited rat peritoneal macrophages. Eur. J. Cell Biol., 2000, 79:343-349
  24. Kocsis I., Vásárhelyi B., Tulassay Zs., Szabó T., Vér Á., Tulassay T.: Determination of H+/K+-ATPase activity in human gastric biopsy specimens. Clin. Chem. Lab. Med., 2000, 38:743-745
  25. Kocsis I., Vásárhelyi B., Szabó T., Vér Á., Tulassay Zs., Tulassay T.: H+/K+-ATPáz enzim aktivitásának meghatározása gyomorbiopsziás mintákból az enzimaktivitás K+-mal való indukálhatóságának alapján. Klin. Kísérl. Lab. Med., 2000, 27:181-188
  26. Kukor Z., Valent S., Tóth M.: Regulation of nitric oxide synthase activity by tetrahydrobiopterin in human placentae from normal and pre-eclamptic pregnancies. Placenta, 2000, 21:763-772
  27. Lakatos K., Tóth I., Nemoda Z., Ney K., Sasvári-Székely M., Gervai J.: Dopamine D4 receptor (DRD4) gene polymorphism is associated with attachment disorganisation in infants. Mol. Psychiatr., 2000, 5:633-637
  28. Malkinson J.P., Lazorova L., Artursson P., Kéri Gy., Tóth I.: Glycolipid-modified peptides: enhancement of absorption of an anti-Tumour somatostatin analogue. Peptides, 2000. 319-320
  29. Nagy E., Mihalik R., Hrabák A., Vértesi Cs., Gergely P.: Apoptosis inhibitory effect of the isothiourea compound, tri-(2-thioureido-S-ethyl)-amine. Immunopharmacology, 2000, 47:25-33
  30. Nardai G., Sass B., Eber J., Orosz Gy., Csermely P.: Reactive cysteines of the 90-kDa heat schock protein, hsp90. Arch. Biochem. Biophys., 2000, 384:59-67
  31. Okada Y., Tsuda Y., Wanaka K., Okamoto U., Okamoto S., Szende B., Kéri Gy.: Plasmin inhibitor, YO-2, induces apoptosis of tumor cell lines through caspase-3 activation. Peptide, 2000, 703-704
  32. Okada Y., Tsuda Y., Wanaka K., Tada M., Okamoto U., Okamoto S., Hijikata-Okunomiya A., Bökönyi Gy., Szende B., Kéri Gy.: Development of plasmin and plasma kallikrein selective inhibitors and their effect on M1 (melanoma) and HT29 cell lines. Bioorg. Med. Chem. Lett., 2000, 10:2217-2221
  33. Rehák M., Csuka I., Szepessy E., Bánfalvi G.: Subphases of DNA replication in drosophila cells. DNA Cell Biol., 2000, 19:607-612
  34. Rónai Zs., Guttman A., Nemoda Zs., Staub M., Kalász H., Sasvári-Székely M.: Rapid and sensitive genotyping of dopamine D4 receptor tandem repeats by automated ultrathin-layer gel electrophoresis. Electrophoresis, 2000, 21:2058-2061
  35. Rónai Zs., Guttman A.: Analytical and micropreparative capillary gel electrophoresis of DNA fragments. Am. Lab., 2000, 28-31
  36. Sahin-Tóth M., Tóth M.: High-affinity Ca2+ binding inhibits autoactivation of rat trypsinogen. Biochem. Biophys. Res. Comm., 2000, 275:668-671
  37. Sahin-Tóth M., Tóth M.: Gain-of-function mutations associated with hereditary pancreatitis enhance autoactivation of human cationic trypsinogen. Biochem. Biophys. Res. Comm., 2000, 278:286-289
  38. Sasvári-Székely M., Gerstner A., Rónai Zs., Staub M., Guttman A.: Rapid genotyping of factor V Leiden mutation using single-tube bidirectional allele-specific amplification and automated ultrathin-layer agarose gel electrophoresis. Electrophoresis, 2000, 21:816-821
  39. Schnaider T., Somogyi J., Csermely P., Szamel M.: The Hsp90-specific inhibitor geldanamycin selectively disrupts kinase-mediated signaling events of T-lymphocyte activation. Cell Stress Chaperones, 2000, 5:52-61
  40. Schnaider T., Sőti Cs., Cheetham M.E., Miyata Y., Yakara I., Csermely P.: Interaction of the human DnaJ homologue, HSJ1b with the 90 kDa heat shock protein, Hsp90. Life Sci., 2000, 67:1455-1465
  41. Seprődi J., Hollósy F., Idei M., Kéri Gy., Teplán I., Füzesi M., Hegedűs T., Sarkadi B.: Synthesis, analysis and biological studies of highly hydrophobic but highly soluble peptidomimetics against MDR. Peptide, 2000, 847-848
  42. Sipeki Sz., Bander E., Farkas Gy., Gujdár A., Ways D.K., Faragó A.: Protein kinase C decreases the hepatocyte growth factor-induced activation of Erk1/Erk2 MAP kinases. Cell. Signal., 2000, 12:549-555
  43. Sőti Cs., Csermely P.: Molecular chaperones and the aging process. Biogerontology, 2000, 1:225-233
  44. Spasokokoutskaja T., Csapó Zs., Sasvári-Székely M., Virga S., Talianidis I., Eriksson S., Staub M.: Effect of phosphorylation on deoxycytidine kinase aczivity. Adv. Exp. Med. Biol., 2000, 486:281-285
  45. Steták A., Vántus T., Bökönyi Gy., Csermely P., Vandenheede J., Ullrich A., Seprődi J., Teplán I., Kéri Gy.: The antitumor somatostatin analogue (TT-232) induced signalling cascades. Peptides, 2000, 39-40
  46. Szende B., Okada Y., Kéri Gy.: Effect of YO-2 (plasmin inhibitor) on the growth of human tumor xenografts in mice. Peptide Sci., 2000, 209-212
  47. Tejeda M., Gaal D., Schwab R.E., Pap A., Szűts T., Kéri Gy.: Influence of various administration routes on the antitumor efficacy of TT-232, a novel somatostatin analog. Anticancer Research, 2000, 20:1023-1028
  48. Tompa A., Jakab M.G., Major J., Idei M., Bocsi J., Mihalik R., Szende B., Kéri Gy.: The somatostatin analogue peptide TT-232 induces apoptosis and chromosome breakage in cultured human lymphocytes. Mutat. Res., 2000, 465:61-68
  49. Vásárhelyi B., Tulassay T., Vér Á., Dobos M., Kocsis I., Seri I.: Developmental changes in erythrocyte Na+, K+-ATPase subunit abundance and enzyme activity in neonates. Arch. Dis. Child. Fetal Neonatal, 2000, 83:F135-F138

1999

  1. Assefa Z., Valius M., Vántus T., Agostinis P., Merlevede W., Vandenheede J.R.: JNK/SAPK activation by platelet-derived growth factor in A431 cells requires both the phospholipase Cγ and the phosphatidylinositol 3-kinase signaling pathways of the receptor. Biochem. Biophys. Res. Commun., 1999, 261:641-645
  2. Bánfalvi G.: Estimating the energy content of metabolites. Biochem. Educ., 1999, 27:79-82
  3. Bánhegyi G., Lusini L., Puskás F., Rossi R., Fulceri R., Braun L., Mile V., Simplicio P., Mandl J., Benedetti A.: Preferential transport of glutathione versus glutathione disulfide in rat liver microsomal vesicles. J. Biol. Chem., 1999, 274:12212-12216
  4. Braun L., Kardon T., El Koulali K., Csala M., Mandl J., Bánhegyi G.: Different induction of gulonolactone oxidase in aromatic hydrocarbon responsive or unresponsive mouse strains. FEBS Lett., 1999, 463:345-349
  5. Braun L., Mile V., Schaff Zs., Csala M., Kardon T., Mandl J., Bánhegyi G.: Induction and peroxisomal appearance of gulonolactone oxidase upon clofibrate treatment in mouse liver. FEBS Lett., 1999, 458:359-362
  6. Buday L.: Membrane-targeting of signalling molecules by SH2/SH3 domain-containing adaptor proteins. Biochim. Biophys. Acta, 1999, 1422:187-204
  7. Csala M., Braun L., Mile V., Kardon T., Szarka A., Kupcsulik P., Mandl J., Bánhegyi G.: Ascorbate-mediated electron transfer in protein thiol oxidation in the endoplasmic reticulum. FEBS Lett., 1999, 460:543-545
  8. Csermely P.: Chaperone-percolator model: a possible molecular mechanism of Anfinsen-cage-type chaperones. BioEssays 1999, 21:959-966
  9. Csermely P.: Limits of scientific growth. Science (Letters) 1999, 284:1622-1623
  10. Diaconu C.C., Szathmáry M., Kéri Gy., Venetianer A.: Apoptosis is induced in both drug-sensitive and multidrug-resistant hepatoma cells by somatostatin analogue TT-232. Br. J. Cancer., 1999, 80:1197-1103
  11. Ferenczi A., Garami M., Kiss E., Pék M., Sasvári-Székely M., Barta Cs., Staub M., Sólyom J., Fekete Gy.: Screening for mutaions of 21-hydroxylase gene in hungarian patients with congenital adrenal hyperplasia. J. Clinic. Endocrinol. Metabol., 1999, 84:2369-2372
  12. Fulceri R., Guinti R., Knudsen J., Leuzzi R., Kardon T., Benedetti A.: Rapamycin inhibits activation of ryanodine receptor from skeletal muscle by the fatty acyl CoA-acyl CoA binding protein complex. Biochem. Biophys. Res. Com., 1999, 264:409-412
  13. Gamberucci A., Fulceri R., Pralong W., Bánhegyi G., Marcolongo P., Sharlene L.W., Benedetti A.: Caffeine releases a glucose-primed endoplasmic reticulum Ca2+ pool in the insulin secreting cell line INS-1. FEBS Lett., 1999, 446:309-312
  14. Henics T., Nagy E., Hyun Ju Oh., Csermely P., Gabain A., Subjeck J.R.: Mammalian hsp70 and hsp110 proteins bind to RNA motifs involved in mRNA stability. J. Biol. Chem., 1999, 274:17318-17324
  15. Hrabák A., Vercruysse V., Vray B., Kahán L.J.: Az indukálható nitrogén-monoxid-(NO-) szintézis gátlása inometacinnal. Szemészet, 1999, 136:215-218
  16. Idei M., Győrffy E., Kiss É., Őrfi L., Seprődi J., Boróka T., Hollósy F., Mészáros Gy., Kéri Gy.: A novel normalized retention factor in micellar electrokinetic chromatography. Electrophoresis, 1999, 20:1561-1567
  17. Kálnay A., Mező I., Móra M., Pályi I., Pató J., Seprődi J., Teplán I., Vincze B.: Synthesis of new poly(N-vinyl pyrrolidone-co-maleic acid)-peptide hormone conjugates with anticancer activity. J. Bioact. Comp. Polym., 1999, 14:304-314
  18. Lengyel T., Sasvári-Székely M., Guttman A.: High-throughput genotyping of factor V Leiden mutation by ultrathin-layer agarose gel electrophoresis. J. Chromatogr. “A”, 1999, 853:519-525
  19. Lofti K., Mansson E., Spasokoukotskaja T., Petterson B., Liliemark J., Peterson C., Eriksson S., Albertioni F.: Biochemical pharmacology and resistance to 2-chloro-2′-arabino-fluoro-2′-deoxyadenosine, a novel analogue of cladribine in human leukemic cells. Clin. Cancer Res., 1999, 5:2438-2444
  20. Mansson E, Spasokoukotskaja T, Sallstrom J, Eriksson S, Albertioni F.: Molecular and biochemical mechanisms of fludarabine and cladribine resistance in a human promyelocytic cell line. Cancer Res., 1999, 59:5956-5963
  21. Őrfi L., Wáczek F., Kövesdi I., Mészáros Gy., Idei M., Horváth A., Hollósy F., Mák M., Szegedi Zs., Szende B., Kéri Gy.: New antitumor leads from a peptidomimetic library. Letters Pept. Sci., 1999, 6:325-333
  22. Pályi I., Vincze B., Lovas S., Mező I., Pató J., Kálnay A., Turi G., Gaál D., Mihalik R., Péter I., Teplán I., Murphy R.F.: Gonadotropin-releasing hormone analogue conjugates with strong selective antitumor activity. Proc. Natl. Acad. Sci., 1999, 96:2361-2366
  23. Puskás F., Marcolongo P., Watkins A.L., Mandl J., Bernard B.A., Houston P., Burchell A., Benedetti A., Bánhegyi G.: Conformational change of the catalytic subunit of glucose-6-phosphatase in rat liver during the fetal-to-neonatal transiton. J. Biol. Chem., 1999, 274:117-122
  24. Sahin-Tóth M., Gráf L., Tóth M.: Trypsinogen stabilization by mutation Arg 117–>His: a unifying pathomechanism for hereditary pancreatitis? Biochem. Biophys. Res. Comm., 1999, 264:505-508
  25. Sasvári-Székely M., Spasokoukotskaja T., Szőke M., Csapó Zs., Turi Á., Szántó I., Eriksson S., Staub M.: Activation of deoxycytidine kinase during inhibition of DNA synthesis by 2-chloro-2′-deoxyadenosine (cladribine) in human lymphocytes. Biochem. Pharmacol., 1999, 56:1175-1179
  26. Schnaider T., Oikarinen J., Ishiwatari-Hayasaka H., Yahara I., Csermely P.: Interactions of hsp90 with histones and related peptides. Life Sci., 1999, 65:2417-2426
  27. Sharom F.J., Xiaohong Yu., Lu Peihua., Liu R., Chu J.W.K., Szabó K., Müller M., Hose C.D., Monks A., Váradi A., Seprődi J., Sarkadi B.: Interaction of the P-glycoprotein multidrug transporter (MDR1) with high affinity peptide chemosensitizers in isolated membranes, reconstituted systems, and intact cells. Biochem. Pharmacol., 1999, 58:571-586
  28. Sipeki Sz., Bander E., Buday L., Farkas G., Bacsy E., Ways D.K., Faragó A.: Phosphatidylinositol 3-kinase contributes to Erk1/Erk2 MAP kinase activation associated with hepatocyte growth factor-induced cell scattering. Cell. Signal., 1999, 11:885-890
  29. Spasokoukotskaja T., Sasvári-Székely M., Keszler G., Albertioni F., Eriksson S., Staub M.: Treatment of normal and malignant cells with nucleoside analogues and etoposide enhances deoxycytidine kinase activity. Eur. J. Cancer, 1999, 35:1862-1867
  30. Staub M.: A hugysav jelentősége az antioxidációs védelemben. Orvosi Hetilap., 1999, 140:275-279
  31. Szegedi Zs., Takács J., Szende B., Vadász Zs., Horváth A., Gulyás É., Tóth G., Peták I., Bocsi J., Kéri Gy.: A specifically radiolabeled somatostatin analog with strong antitumor activity induces apoptosis and accumulates in the cytosol and the nucleus of HT29 human colon carcinoma cells. Endocrine, 1999, 10:25-34
  32. Szőke M., Sasvári-Székely M., Barta Cs., Guttman A.: Human dopamine D4 receptor allele genotyping by ultrathin agarose gel electrophoresis with to-Pro-3 complexation. Electrophoresis, 1999, 20:497-501
  33. Szőke M., Sasvári-Székely M., Guttman A.: Ultra-thin-layer agarose gel electrophoresis I. Effect of the gel concentration and temperature on the separation of DNA fragments. J. Chromatography “A” 1999, 830:465-471
  34. Szőnyi M., Csermely P., Sziklai I.: Acetylcholine-induced phosphorylation in isolated outer hair cells. Acta Otolaryng., 1999, 119:185-188
  35. Tejeda M., Gaal D., Schwab R.E., Pap A., Kéri Gy.: In vivo antitumor activity of TT-232, a novel somatostatin analog. Anticancer Res., 1999, 19:497-501
  36. Tóth I., Malkinson J.P., Flinn NS., Drouillat B., Horváth A., Érchegyi J., Idei M., Venetianer A., Artursson P., Lazorova L., Szende B., Kéri Gy.: Novel lipoamino acid- and liposaccharide-based system for peptide delivery: application for oral administration of tumor-selective somatostatin analogues. J. Med. Chem., 1999, 42:4010-4013
  37. Vásárhelyi B., Dobos M., Vér Á., Nobilis A., Kocsis I., Szabó T., Seri I., Tulassay T.: A Na+/K+-pumpa működése kora- és érett újszülöttekben. Gyermekgyógyászat, 1999, 6:578-584
  38. Vásárhelyi B., Szabó T., Vér Á., Nobilis A., Tulassay T.: Autómatizált módszer kifejlesztése a Na+/K+ ATP-áz aktivitás mérésére humán vörösvérsejtekben. Klin. Kís. Lab. Med., 1999, 26:64-69
  39. Wunderlich L., Faragó A., Downward J., Buday L.: Association of nck with tyrosine-phosporylated ASL-76 in activated T lymphocytes. Eur. J. Immunol., 1999, 29:1068-1075
  40. Wunderlich L., Faragó A., Buday L.: Characterization of interactions of nck with sos and dynamin. Cell Signal., 1999, 11:25-29
  41. Wunderlich L., Gohér Á., Faragó A., Downward J., Buday L.: Requirement of multiple SH3 domains of nck for ligand binding. Cell Signal., 1999, 11:253-262

1998

  1. Bajor T., Southan G.J., Salzman A.L., Szabó Cs., Hrabák A.: Theoretical approximation of partial selectivity of nitric oxide synthase (NOS) isoenzyme sulfur-based inhibitors. Med. Sci. Mon. Lab. Invest., 1998, 4:587-595
  2. Bánhegyi G., Braun L., Csala M., Puskás F., Somogyi A., Kardon T., Mandl J.: Ascorbate and environmental stress. Annals of the N. Y. Acad. Sci., 1998, 851:292-303
  3. Bánhegyi G., Marcolongo P., Puskás F., Fulceri R., Mandl J., Benedetti A.: Dehydroascorbate and ascorbate transport in rat liver microsomal vesicles. J. Biol. Chem., 1998, 273:2758-2762
  4. Bánhegyi G., Marcolongo P., Burchell A., Benedetti A.: Heterogeneity of glucose transport in rat liver microsomal vesicles. Arch. Biochem. Biophys., 1998, 359:133-138
  5. Braun L., Coffey M.J., Puskás F., Kardon T., Nagy G., Conley A.A., Burchell B., Mandl J.: Molecular basis of UDP-glucuronosyltranferase induction in spontaneously diabetic rats, aceton-treated rats and starved rats. Biochem. J., 1998, 336:587-592
  6. Barta Cs., Sasvári-Székely M., ,Guttman A.: Simultaneous analysis of various mutations on the 21-hydroxylase gene by multi-allele specific amplification and capillary gel electrophoresis. J. Chromatography A., 1998, 817:281-286
  7. Csala M., Léránt I., Bánhegyi G., Kardon T., Puskás F., Mucha I., Machovich R., Falus A., Mandl J.: Prostaglandin-independent stimulation of interleukin-6 production by fibrinogen degradation product D in perfused murine liver. Scand. J. Immunol., 1998, 48:269-271
  8. Csapó Zs., Keszler G., Sasvári-Székely M., Smid K., Noordhuis P., Peters G.J. Staub M.: Similar changes were induced by cladribine and by gemcitabine, in the deoxypyrimidine salvage, during short term treatments. Advances Exp. Med. Biol., 1998, 431:525-529
  9. Csermely P., Lakhotia S.C.: Molecular biology of stress responses in India. Cell Stress Chaperones, 1998, 3:1-5
  10. Csermely P., Schnaider T., Szántó I.: Posibble nuclear functions of the major molecular chaperones of the eukaryotic cytoplasm, Hsp90. Current Sciences, 1998, 74:442-445
  11. Csermely P., Schnaider T., Sőti Cs., Prohászka Z., Nardai G.: The 90-kDa molecular chaperone family:structure, function, and clinical applications. A comprehensive review. Pharmacol. Ther., 1998, 79:129-168
  12. Guttman A., Barta Cs., Szőke M., Sasvári-Székely M., Kalász H.: Real-time detection of allele-specific polymerase chain reaction products by automated ultra-thin-layer agarose gel electrophoresis. J. Chromatogr. “A”, 1998, 828:48l-487
  13. Györffy E., Pató J., Horváth A., Érchegyi J., Teplán I., Kéri Gy., Idei M.: Analysis of polyanionic macromolecular carrier poly (N-vinylpyrrolidone-co-maleic acid) and its bioconjugates by capillary electrophoresis. Electrophoresis, 1998, 19:295-299
  14. Györffy E., Pató J., Horváth A., Érchegyi J., Teplán I., Kéri Gy., Idei M.: Behaviour of macromolecular drug carrier poly(N-vinyl pyrrolidone-comaleic acid) and its bioconjugates at different pH values investigated by gel permeation chromatography. J. Liq. Chrom. Rel. Technol., 1998, 21:2341-2353
  15. Hrabák A., Sefrioui H., Vercruysse V., Temesi Á., Bajor T., Vray B.: Action of chloroquine on nitric oxide production and parasite killing by macrophages. Eur. J. Pharmacol., 1998, 354:83-90
  16. Idei M., Seprődi J., Györffy E., Hollósy F., Vadász Zs., Mészáros Gy., Teplán I., Kéri Gy.: Micellar electrokinetic chromatography of highly hydrophobic peptides. Anal. Chim. Acta, 1998, 372:273-279
  17. Kéri Gy.: Antitumor hatású molekulák. Jeltovábbitás-gátlás és programozott sejthalál-indukálás. Magyar Tudomány, 1998, 9:1082-1090
  18. Koppán M., Kovács M., Mező I., Flerkó B.: Electrochemical stimulation of the median eminence evokes FSH but not LH release after LHRH antagonist treatment in vivo and in vitro. Neuroendocrinol., 1998, 10:231-236
  19. Lovas S., Pályi I., Vincze B., Horváth J., Kovács M., Mező I., Tóth G., Teplán I., Murphy R.F.: Direct anticancer activity of gonadotropin-releasing hormone-III. J. Pept. Res., 1998, 52:384-389
  20. Mihály K., Tóth S., Szlávik A., Tóth A., Csermely P.: Attenuation of diabetic retinopathy by the molecular chaperone-inducer amino acid analogue canavanine in streptozotocin-diabetic rats. Cell. Mol. Life. Sci., 1998, 54:1154-1160
  21. Marcolongo P., Bánhegyi G., Benedetti A., Hinds C.J.: Liver Microsomal transport of glucose-6-phosphate, glucose, and phosphate in type glycogen storage diseases. J. Clin. Endocrinol. Metabol., 1998, 83:224-229
  22. Puskás F., Braun L., Csala M., Kardon T., Marcolongo P., Benedetti A., Mandl J., Bánhegyi G.: Gulonalactone oxidase activity-dependent intravesicular glutathione oxidation in rat liver microsomes. FEBS Lett., 1998. 430:293-296
  23. Sasvári-Székely M., Spasokoukotskaja T., Szőke M., Csapó Zs., Turi Á., Szántó I., Erikkson S., Staub M.: Activation of deoxycytidine kinase during inhibition of DNA synthesis by 2-chloro-2-deoxyadenosine (cladrinine) in human lymphocytes. Biochem. Pharmacol., 1998, 56:1175-1179
  24. Sasvári-Székely M., Csapó Zs., Spasokoukotskaja T., Erikkson S., Staub M.: Activation of deoxycytinide kinase during inhibition of DNA synthesis in human lymphocytes. Adv. Exp. Med. Biol., 1998, 431:519-522
  25. Schnaider T., Somogyi J., Csermely P., Szamel M.: The Hsp90-specific inhibitor, geldanamycin blocks CD28-mediated activation of human T lympocytes. Life Sci., 1998, 63:949-954
  26. Sőti Cs., Csermely P.: Characterization of the nucleotide binding properties of the 90 kDa heat shock protein (Hsp90). J. Biosci., 1998, 23:347-352
  27. Sőti Cs., Radics L., Yahara I., Csermely P.: Interaction of vanadate oligomers and permolybdate with the 90-kDa heat-shock protein, hsp90. Eur. J. Biochem., 1998, 255:611-617
  28. Sőti Cs., Csermely P.: Molecular chaperones in the etiology and theraphy of cancer. Path. Oncol. Res., 1998, 4:316-321
  29. Spasokoukotskaja T., Sasvári-Székely M., Hullán L., Albertioni F., Eriksson A., Staub M.: Activation of deoxycytidine kinase by various nucleoside analogues. Adv. Exp. Med. Biol., 1998, 431:641-645
  30. Staub M., Csapó Zs., Spasokoukotskaja T., Sasvári-Székely M.: Deoxycytidine kinase can be also potentiated by the G-protein activator NaF in cells. Adv. Exp. Med. Biol., 1998, 431:425-428
  31. Szaleczky E., Prechl J., Ruzicska É., Fehér J., Braun L., Bánhegyi G., Csala M., Mandl J., Somogyi A.: Reduction of glycated hemoglobin levels by long term, high dose ascorbic acid supplementation in helthy and diabetic patients. Med. Sci. Monit., 1998, 4:241-244
  32. Tóth M., Kukor Z., Sahin-Tóth M.: Differencial response of basal and tetrahydrobiopterin stimulated activities of placental type III. nitric oxide synthase to sodium dodecyl sulphate: relation to dimeric structure. Mol. Human Reprod., 1998, 4:1165-1172
  33. Tóvári J., Szende B., Bocsi J., Falaschi A., Simoncsits A., Pongor S., Érchegyi J., Steták A., Kéri Gy.: A somatostatin analogue induces translocation of Ku 86 autoantigen from the cytosol to the nucleus in colon tumour cells. Cell Signal., 1998, 10:277-282
  34. Vadász Zs., Sziráki I., Sasvári M., Kabai P., Murthy L.R., Saito M., Laszlovszky I.: Analysis of the mesotelencephalic dopamine system by quantitative-trait locus introgression. Neurochem. Res., 1998, 23:1337-11354
  35. Vásárhelyi B., Vér Á., Mobilis A., Szabó T., Tulassay T.: Functional and structural properties of Na+/K+-ATPase enzyme in neonatal erythrocytes. Eur. J. Clinical Invest., 1998, 28:543-545

1997

  1. Bánfalvi G., Mikhailova M., Poirier L.A., Chou M.W.: multiple subphases of DNA replication in chinese hamster ovari (CHO-K1) cells. DNA Cell Biol., 1997, 16:1493-1498
  2. Bánfalvi G., Poirier L.S., Mikhailova M., Chou M.W.: Relationship of repair and replicative DNA synthesis to cell cycle in chinese hamster ovary (CHO-K1) cells. DNA Cell Biol., 1997, 16:1155-1160
  3. Bánhegyi G., Braun L., Csala M., Puskás F., Mandl J.: Ascorbate metabolism and its regulation in animals. Free Radic. Biol. Med., 1997, 23:793-803
  4. Bánhegyi G., Marcolongo P., Fulceri R., Hinds C., Burchell A., Benedetti A.: Demonstration of a metabolically active glucose-6-phosphate pool in the lumen of liver microsomal vesicles. J. Biol. Chem., 1997, 272:23584-13590
  5. Braun L., Puskás F., Csala M., Mészáros Gy., Mandl., Bánhegyi G.: Ascorbate as a substrate for glycolysis or gluconeogenesis: evidence for a interorgan ascorbate cycle. Free Radic. Biol. Med., 1997, 23:804-808
  6. Braun L., Kardon T., Puskás F., Csala M., Bánhegyi G., Mandl J.: Regulation of glucuronidation by glutathione redox state through the alteration of UDP-glucose supply originating fron glycogen metabolism. Arch. Biochem. Biophys., 1997, 348:169-173
  7. Csala M., Bánhegyi G., Braun L., Klebovich I., Mandl J.: Decrease of gluconeogenesis by deramciclane is counteracted by cytochrome P450 inhibitors. Pharmac. Sci., 1997, 3:469-472
  8. Csermely P., Miyata Y., Sőti Cs., Yahara I.: Binding affinity of proteins to hsp90 correlates with both hydrophobicity and positive charges. A surface plasmon resonance study. Life Sci., 1997, 61:411-418
  9. Csermely P.: Proteins, RNAs ans chaperones in enzyme evolution: a folding perspective. TIBS, 1997, 22:147-149
  10. Csuka I., Bánfalvi G.: Analysis of 5′-termini of early intermediates of Okazaki fragments accumulated in thymocytes after emetine treatment of mice. DNA Cell Biol., 1997, 16:979-984
  11. Hrabák A., Bajor T., Southan G.J., Salzman A.L., Szabó Cs.: Comparison of the inhibitory effect of isothiourea and mercaptoalkylguanidine derivatives on the alternative pathway of arginine metabolism in macrophages. Life Sci., 1997, 60:395-401
  12. Hrabák A., Bajor T., Temesi Á., Mészáros Gy.: Studies on the structural backgrounds of the cross-inhibition of the products in the arginine metabolism of macrophages. Med. Sci. Mon., 1997, 3:299-304
  13. Lukácsi L., Bánhidy F., László Á., Zsolnai B., Somogyi J.: The role of changes in Mg-Ca ratio of the myometrium during normal and abnormal labour. Advances Magnesium Res., 1997, 256-259
  14. Mező I., Lovas S., Pályi I., et.al. (Vadász Zs., Seprődi J., Idei M., Teplán I.,) Murphy R.F.: Synthesis of gonadotropin-releasing hormone III. analogs. Structure-antitumor activity relationships. J. Med. Chem., 1997, 40:3353-3358
  15. Mócsai A., Bánfi B., Kapus A., Farkas Gy., Buday L., Faragó A., Ligeti E.: Differential affects of thyrosine kinase inhibitors and an inhibitor of the mitogen activated protein kinase cascade on degranulation and superoxide productions of human neutrophil granulocytes. Biochem. Pharmacol., 1997, 54:781-789
  16. Phaneuf S., Asbóth G., Carrasco M.P., Europe-Finner G.N., Saji F., Kimura T., Harris A., López Bernal A.: The desensitization of oxytocin receptors in human myometrial cells is Accopmanied by down-regulation of oxytocin receptor messenger RNA. J. Endocrinol., 1997, 154:7-18
  17. Prohászka Z., Mémet K., Csermely P., Hudecz F., Mező G., Füst G.: Defensins purified from human granulocytes bind Clq and activate the classical complement pathway like the transmembrane glycoprotein gp41 of HIV-1. Mol. Immunol., 1997, 34:809:816
  18. Sahin Tóth M., Kukor Z., Tóth M.: Tetrahydrobiopterin prefentially stimulates activity and promotes subunit aggregation of membrane-bound calcium-dependent nitric oxide synthase in human placenta. Mol. Human Reopr., 1997, 3:293-298
  19. Somogyi A., Szaleczky E., Pusztai P., Braun L., Sármán B.: A plazma antioxidánsai II. tipusu cukorbetegekben. Magy. Belorv. Arch., 1997, 50:187-192
  20. Szászi K., Buday L., Kapus A.: Shrinkage-induced protein tyrosine phosphorylation in chinese hamster ovary cells. J. Biol. Chem., 1997, 272:16670-16678
  21. Tóth M.: Stimulation of phosphatidylcholine turnover by β-phorbol ester and diacylglycerol in the primordial human placenta: the suggested role of phospholipase D activation. Placenta, 1997, 18:411-419
  22. Tóth M., Kukor Z., Sahin-Tóth M.: Activation and dimerization of type III nitric oxide synthase by submicromolar concentrations of tetrahydro- biopterin in microsomal preparations from human primordial placenta. Placenta, 1997, 18:189-196
  23. Vásárhelyi B., Szabó T., Vér Á., Tulassay T.: Measurement of Na+/K+-ATPase activity with an automated analyzer. Clin. Chem., 1997, 43:1986-1987
  24. Vér Á., Szántó I., Bányász T., Csermely P., Végh E., Somogyi J.: Changes in the expression of Na+/K+-ATPase isoenzymes in the left ventricle of diabetic rat hearts: effect of insulin treatment. Diabetologia, 1997, 40:1255-1262
  25. Wang J., Vántus T., Merlevede W., Vandenheede J.R.: Identification and characterization of an auto-activating MEK kinase from bovine brain: phosphorylation of serine-298 in the proline-rich domain of the mammalian MEKs1. Int. J. Biochem. Cell. Biol., 1997, 29:1071-1083
  26. Wu X., Merup M., Juliusson G., Jansson M., Stellan B., Grander D., Zabarovsky E., Liu Y., Spasokukotskaja T., Gahrton G., Einhorn S.: Characterization of a hairy cell leukemia-associated 5q13.3 inversion breakpoint. Genes, Chromosomes Canc., 1997, 20:337-346

1996

  1. Asbóth G., Phaneuf S., Europe-Finner N.G., Tóth M., López B.A.: Prostaglandin E2 activates phospholipase C and elevates intracellular calcium in cultured myometrial cells: involvement of EP1 and EP3 receptor subtypes. Endocrinology, 1996, 137:2572-2579
  2. Bánhegyi G., Csala M., Braun L., Garzó T., Mandl J.: Ascorbate synthesis-dependent glutathione consumption mouse liver. FEBS Lett.,1996, 381:39-41
  3. Bánhegyi G., Braun L., Marcolongo P., Csala M., Fulceri R., Mandl J., Benedetti A.: Evidence for an UDP-glucuronic acid/phenol glucuronide antiport in rat liver microsomal vesicles. Biochem. J., 1996, 315:171-176
  4. Bánhegyi G., Csala M., Mandl J., Burchell B., Marcolongo P., Fulceri R., Benedetti A.: Fatty acyl-CoA esters and the permeability of rat liver microsomal vesicles. Biochem. J., 1996, 320:343-344
  5. Braun L., Puskás F., Csala M., Győrffy E., Garzó T., Mandl J., Bánhegyi G.: Gluconeogenesis from ascorbic acid: ascorbate recycling isolated murine hepatocytes. FEBS Lett., 1996, 388:183-186
  6. Braun L., Csala M., Poussu A., Garzó T., Mandl J., Bánhegyi G.: Glutathione depletion induces glycogenolysis dependent ascorbate synthesis in isolated murine hepatocytes. FEBS Lett., 1996, 288:173-176
  7. Buday L., Khwaja A., Sipeki Sz. Faragó A., Downward J.: Interactions of cbl with two adaptor proteins, grb2 and crk, upon T cell activation. J. Biol. Chem., 1996, 271:6159-6163
  8. Carrasco M.P., Phaneuf S., Asbóth G., Bernal A.L.: Fluprostenos activates phospholipase C and Ca2+mobilization in human myometrial cells. J. Clin. Endocrin. Metabol., 1996, 81:2104-2110
  9. Csala M., Bánhegyi G., Kardon T., Fulceri R., Gamberucci A., Giunti R., Benedetti A., Mandl J.: Inhibition of glucuronidation by an acyl-CoA-mediated indirect mechanism. Biochem. Pharmacol., 1996, 52:1127-1131
  10. Csermely P., Sőti Cs., Schnaider T., Steták T., Somogyi J.: Magreceptorok. Orvosképzés, 1996, 3:176-181
  11. Fazekas K., Bánfalvi G., Molnár B., Csuka I., Láng I., Tompos G., Sreter L.: Elevated nascent DNA content of peripheral blood mononuclear cell compartment in lymphoma patients. Anticancer Res., 1996, 16:505-510
  12. Hertelendy F., Shimada K., Tóth M., Molnár M., Tanaka K.: Regulation of oviposition. Adv. in Organ. Biol., 1996, 1996, 1:31-59
  13. Holtey M., Csermely P., Niggermann J., Eckel J.: Insulin-induced phosphorylation of a 38 kDa DNA-binding protein in ventricular cardiomyocytes: possible implication of nuclear protein phosphatase activity. Mol. Cell. Endocrin., 1996, 120:107-114
  14. Hrabák A., Bajor T., Temesi Á.: Computer-aided comparison of the inhibition of arginase and nitric oxide synthase in macrophages by amino acids not related to arginine. Comp. Biochem. Physiol., 1996, 1138:375-381
  15. Hrabák A., Bajor T., Temesi Á., Mészáros G.: The inhibitory effect of nitrite, a stable product of nitric oxide (NO) formation, on arginase. FEBS Lett., 1996, 390:203-206
  16. Idei M., Kiss É., Kéri Gy.: Calculation of modified capacity factor in micellar electrokinetic chromatography. Electrophoresis, 1996, 17:762:765
  17. Idei M., Mező I., Vadász Zs., Horváth A., Seprődi J., Érchegyi J., Teplán I., Kéri Gy.: Comparative analysis of somatostatin analog peptides by capillary electrophoresis and micellar elektrokinetic chromatography. Electrophoresis, 1996, 17:758-761
  18. Idei M., Mező I., Szabó E.Z., Kéri Gy.: Investigation of the chemical stability of a new growth hormone-releasing hormone (GHRH) analogue by HPLC. Biomed. Chromatogr., 1996, 10:89-91
  19. Idei M., Dibó G., Bogdán K., Mező G., Horváth A., Érchegyi J., Mészáros Gy., Teplán I., Kéri Gy., Hudecz F.: Analysis of macromoleculat branched chain polypeptides by capillary electrophoresis and micellar electrokinetic chromatography. Electrophoresis, 1996, 17:1357-1360
  20. Kalapos M.P., Riba P., Garzó T., Mandl J.: Gluconeogenic precursors stimulate acetone metabolism in isolated murine hepatocytes. Int. J. Biochem., 1996, 28:705-709
  21. Kalapos M.P., Riba P., Mand J.: Glucose formation from methylglyoxal in hepatocytes from streptozotocin-induced diabetic mice: the effect of insulin. Experientia, 1996, 52:827-830
  22. Kéri Gy. Érchegyi J., Horváth A., Mező I., Idei M., Vántus T., Balogh Á., Vadász Zs., Bökönyi Gy., Seprődi J., Teplán I., Csuka O., Tajeda M., Gaáz Zs., Szegedi Zs., Szende B., Roze C., Kalhoff H., Ullrich A.: A tumor-selective somatostatin analogue (TT-232) with strong in vitro and in vivo antitumor activity. Proc. Natl. Acad. Sci. USA, 1996, 93:12513-12518
  23. Kukor Z., Mészáros Gy., Hertelendy F., Tóth M.: Calcium-dependent Nitric Oxide Synthesis is Potently Stimulated by Tetrahydrobiopterin in Human Primordial Placenta. Placenta, 1996, 17:69-73
  24. Merup M., Spasokoukotskaja T., Einhorn S., Smith E., Gahrton G., Juliusson G.: Bcl-2 rearrangements with breakpoints in both vcr and mbr in non-Hodgkin’s lymphomas and chronic lymphocytic leukaemia. Br. J. Haematol., 1996, 92:647-652
  25. Mező I., Seprődi J., Vadász Zs., Teplan I., Murphy R.F.: Antitumor activity of GnRH analogs and their conjugates with poly-(N-vinylpyrrolidne-co-maleic acid). Pept. Chem. Struct. Biol., 1996, 236-240
  26. Mező I., Seprődi J., Vincze B., Pályi I., Kéri Gy., Vadász Zs., Tóth G., Kovács M., Koppán M., Horváth J.E., Kalnay A., Teplan I.: Synthesis of GnRH analogs having direct antitumor and low LH-releasing activity. Biomed. Pept. Proteins. Nucleic. Acids, 1996, 2:33-40
  27. Mező G., Mező I., Pimm M.V., Kajtár J., Seprődi J., Teplán I., Kovács M., Vincze B., Pályi I., Idei M., Szekérke M., Hudecz F.: Synthesis, conformation, biodistribution, and hormone-related in vitro antitumor activity of a gonadotropin-releasing hormone antagonist-branched polypeptide conjugate. Bioconjug. Chem., 1996, 7:642-650
  28. Mihalik R., Farkas Gy. Kopper L., Benczur M., Faragó A.: possible involvement of protein kinase C-e in phorbol ester-induced growth inhibition of human lymphoblastic cells. Int. J. Biochem. Cell Biol., 1996, 28:925-933
  29. Nardai G., Schnaider T., Sőti Cs., Tryan I., Hoj P.B., Somogyi J., Csermely P.: Characterization of the 90 kDa heat shock protein (HSP90)-associated ATP/GTPase. J. Biosci., 1996, 21:179-190
  30. Őrfi L., Kökösi J., Szász Gy., Kövesdi I., Mák M., Teplán I., Kéri Gy.: Heterocondensed quinazolones: synthesis and protein-tyrosine kinase inhibitory activity of 3,4-Dihydro-1H,6H-(1,4)oxazino-(3,4-b)quinazolin-6-one derivatives. Bioorg. Med. Chem., 1996, 4:547-555
  31. Pályi I., Vincze B., Kálnay A., Turi G., Mező I., Teplán I., Seprődi J., Pató J., Móra M.: Effect of gonadotropin-releasing hormone analogs and their conjugates on gonadotropin-releasing hormone receptor-positive human cancer cell lines. Cancer Detect. Prevent., 1996, 20:146-152
  32. Staub M., Sasvári-Székely A., Spasokukotskaja T., Piróth Zs., Kazimierczuk Z.: Human tonsillar lymphocytes as targets for immunosuppressive and anticancer drugs. Acta Otolaryng., 1996, Suppl. 523:124-127
  33. Strawn L.M., McMahon G., App H., Schreck R., Kuchler W.R., Longhi M.P., Hui T.H., Tang C., Levitzki A., Gazit A., Chen I., Kéri G., Őrfi L., Risau W., Flamme I., Ullrich A., Hirth K.P., Shawver L.K.: Flk-1 as a target for tumor growth inhibition. Cancer Res., 1996, 56:3540-3545
  34. Szende B., Kéri Gy., Szegedi Zs., Benedeczky I., Csikós A., Őrfi L., Gazit A.: Tyrphostin induces non-apoptotic programmed cell death in colon tumor cells. Cell Biol. Inter., 1996, 19:903-911
  35. Szikla K., Sasvári-Székely M., Spasokukotskaja T., and Staub M.: Pyrimidine deoxyribonucleosides are phosphorylated to triphosphates at low temperatures too, but are not incorporated into DNA or phospholipids. Nucleosides and Nucleotides, 1996, 15:1657-1668
  36. Tóth M.: Phosphatidylcoline cycle: an intracellular sgnaling mechanism in the promordial human placenta. Acta Physiol. Hung., 1996, 84:99-108
  37. Vadász Zs., Seprődi J., Teplán I.: Studies on epimerization-free methods for the preparation of aminosuccinyl peptides. Lett. Pept. Sci., 1996, 2:339-344
  38. Vincze B., Pályi I., Gaál D., Pató J., Móra M., Mező I., Teplán I., Seprődi J.: In vivo studies of the new gonadotropin-releasing hormone antagonist-copolymer conjugates having antitumor activity. Cancer Detect. Prevent., 1996, 20:153-159

1995

  1. Balogh Á., Csuka O., Teplán I., Kéri Gy.: Phosphatidylcholine could be the source of 1,2-DAG which activates protein kinase C in EGF-stimulated colon carcinoma cells (HT29). Cell Sign., 1995, 7:793-801
  2. Bánfalvi G.: Constructing energy maps of metabolic cycles. Biochem. Ed., 1995, 23:83-85
  3. Bánfalvi G., Sarkar N.: Effect of mercury substitution of DNA on its susceptibility to cleavage by restriction endonucleases. DNA and Cell Biol., 1995, 14:445-450
  4. Bánhegyi G., Mucha I., Garzó T., Antoni F., Mandl J.: Endotoxin inhibits glucuronidation in the liver. An effect mediated by intercellular communication. Biochem. Pharmacol., 1955, 49:65-68
  5. Bányász T., Vér Á., Kovács T.: Transformation and recovery of rat skeletal muscles in pathologic hormonal states1. Acta Physiol. Hung., 1995, 83:279-287
  6. Braun L., Fulceri R., Benedetti A., Mandl J., Bánhegyi G.: Inhibition of p-nitrophenol glucuronidation by calcium mobilising hormones. Xenobiotica, 1995, 25:1073-1079
  7. Buday L., Warne Patricia H., Downward J.: Down regulation of the ras activation pathway by MAP kinase phosphorylation of Sos. Oncogene, 1995, 11:1327-1331
  8. Csermely P., Miyata Y., Schnaider T., Yahara I.: Autophosphorylation of grp94 (Endoplasmin). J. Biol. Chem., 1995, 170:6381-6388
  9. Csermely P., Pénzes I., Tóth S.: Chronic overcrowding decreases cytoplasmic free calcium levels in T lymphocytes of aged CBA/CA mice. Experimentia, 1995, 51:976-979
  10. Csermely., Tóth S.: Changes in intracellular calcium metabolism in T lymphocytes after transient and persistent psychosocial stress of mice of various ages. Age Vault. Int. Inst. Agein., 1995, 245-250
  11. Csermely P., Schnaider T., Szántó I.: Signalling and transport through the nuclear membrane. Biochim. Biophys. Acta, 1995, 1241:425-452
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