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Address
H-1089 Budapest, Nagyvárad sq 4. Floor XIV
Phone +36-1-210-0278 ext: 56318
Contact to the head of the institute: vasarhelyi.barna@med.semmelweis-univ.hu

Acting Directors
General: Prof. Barna Vásárhelyi  MD., PhD., DSc. (vasarhelyi.barna@med.semmelweis-univ.hu)

Education: Prof. Barna Vásárhelyi  MD., PhD., DSc. (vasarhelyi.barna@med.semmelweis-univ.hu)

Background
The Department of Laboratory Medicine was founded in 2010 with missions on the following areas:

  • Education. The main goal is the introduction of basic principles of Laboratory Medicine to graduate medical students. The Department also provides post-graduate education for health-care specialists including physicians and clinical biochemists.
  • Diagnostics. It coordinates laboratory tests at the majority of University and provides professional support for clinical decision making.
  • Research. The Department actively participates in research studies involving laboratory tests; it also manages research projects of its own. The Department manages its own PhD program.

Education
The Laboratory Medicine curriculum is based on knowledge acquired during studies of Pathophysiology and Clinical Laboratory Diagnostic obtained during the third year. The major goal is to present some approach and diagnostic algorithms that are required for efficient test ordering and evaluation of lab test results. As part of education the students obtain information regarding:

  •          the procedure that generates laboratory test results (from test ordering to laboratory reports)
  •          laboratory tests needed to establish a diagnosis
  •          the major aspects that the medical doctors should take into account when they evaluate a laboratory report
  •          novel techniques used in general laboratory (with their drawbacks and benefits).

Lectures
Classroom lectures “Laboratory Medicine” for 4th  year medical students
Academic year 2013/2014 semester 2 (spring semester)
Monday, Nagyvárad sq. NET Green Lecture room 8:00 – 9:10 (70 minutes)

The participation in the tuition is obligatory.
The digital slides are available for the students via our website (www.semmelweis.hu/laboratorium).

The participation on lectures is highly recommended, since the exam is partly based on them. The topics of the lectures include the elements of general and practical clinical laboratory.

The areas to be covered by the planned lectures:

1.       Introduction in Laboratory Medicine (Specimen collection and processing. Preanalytical variables. To identify the major factors interfering with laboratory tests.Establishment and use of reference values/intervals.)

2.       Concepts in Laboratory Medicine (Interpretation of laboratory test results: sensitivity and specificity of a laboratory test, predictive values. Quality control, quality assurance in clinical laboratories.)

3.       Laboratory investigations of hematology diseases. (To understand the basic principles of modern hematology analyzers in clinical laboratories.)

4.       Laboratory investigations of hemostatic disorders. (Identify the appropriate laboratory tests for evaluation of the bleeding patient and the thrombotic patient.)

5.       Laboratory investigations of inflammation and tissue damage. (To understand how cell injury and inflammation can be tracked through plasma markers.)

6.       Immunological investigations in laboratory medicine. (Learn the diagnostic tests required to the assessment of autoimmune disorders.)

7.       Laboratory enzyme diagnostics        

8.       Endocrine investigations in laboratory medicine (Understand the laboratory tests used in the diagnosis of the more commonly encountered endocrine disorders.)

9.       Molecular genetics investigation in laboratory medicine     

10.   Therapeutic drug monitoring  (To learn when therapeutic drug monitoring is required and how it is performed for commonly monitored drugs. To identify the common drugs of abuse and learn how they are detected.)

11.   Laboratory investigations of tumor markers                                                                                                             

12.   Laboratory investigations of cerebrospinal fluid and ascites, pleural fluid           

13.   To learn the laboratory tests used near patients (Point of care testing)   

14.   To learn the rationale for selection of laboratory tests in pediatrics including neonatal screening programs.

We provide consultation and laboratory visit during the semester.

 

Exam

The exam is a written test.

The material for examination is based on the lectures. The questions are prepared by lectures.

The exam consists of 50 questions. The students have 60 minutes for writing test.

The test questions include simple choice (one correct answer out of 4 or 5 options).

Test results of exam are available within one day.

Evaluation:  0-60% = 1 (Failed)        61-70% = 2        71-80% = 3        81-90% = 4        91-100% = 5

Exam dates: You will be notified about the dates offered by the Department before the exam period and they will be finalized at the Staff-Student meeting.

Taking examination before the exam period is not allowed.

The sign up procedure is controlled and regulated by the NEPTUN software and the Department cannot interfere with system. The officially signed up student will be scheduled for examination. The list of examinees is completed 2 days before the date of exam; then NEPTUN system automatically closes the sign up list.

Diagnostic profile of the Department
The Central Laboratory at Semmelweis University forms the basis of the Department. It performs more than 400 different tests in the field of clinical chemistry, hematology, hemostasis, serology, endocrinology, therapeutic drug level monitoring and clinical microbiology with an annual number over 3 million. The laboratory is classified as FJ-3 meaning that it provides a 24 hour service for 7 days a week.  Laboratory reports are provided through GLIMS lab informatics system integrated to eMedSolution.

Research at the Department
Laboratory tests are performed in the majority of clinical studies and drug research. In order to use the results more efficiently the colleague who is directly involved in performing the lab tests also participates in study design and evaluation. Therefore, clinical laboratories at the University are active partners of researchers and medical doctors. The major research profile of the Institute is to characterize specific patterns of biomarkers predictive for specific disorders. Characteristic examples are the determination of immune phenotype and analysis of kinetic alteration of intracellular analytes with flow cytometry, measurement of cytokine levels with biochips, genomic analyses (genotyping and gene expression arrays). These instruments and the professional knowledge are also available for research purposes. Medical students are welcome to do research in any of the fields listed above.