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Immunopathology group

Staff:

Zoltán Prohászka, MD, PhD, DSc, Group leader
Dorottya Csuka, MSc, PhD, Ágnes Szilágyi, MSc, PhD, György Sinkovits,MD, resident for laboratory medicine
Eszter Trojnár, MD, PhD Student, Blanka Mező, MSc, PhD Student


Profile
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The main focus of the research in the immunopathology research groups is on the complex studies on the pathogenesis of thrombotic microangiopathies, complement mediated kidney diseases, and other complex diseases with inflammatory mechanisms. In the context of such complex clinical studies we measure various autoantibodies, complement-proteins, cytokines and markers of stress and inflammation. We also perform genetic determinations to identify disease related risk variants or causative mutations. 

Clinical research is tightly linked to our diagnostic activities, with focus on thrombotic thrombocytopenic purpura, hemolytic uremic syndrome and complement mediated kidney diseases. 

Research in our group is financed by the Semmelweis University, and by the various thematic grats of the National Research, Development and Innovation Office.

Recently closed grants are following:

Analysis of interactions between inflammatory and vasoregulatory pathways in chronic heart failure: application of logical analysis of data, a novel data-mining tool (2008-2011, PI Zoltán Prohászka) Publications

Studies on the etiopathogenesis of thrombotic microangiopathies (2012-2015, PI Zoltán Prohászka) Publications

Ongoing project: 

Studies on the role of complement in antibody mediated rejection of kidney transplants (2014-2019, in collaboration with the Medical University of Vienna)

Former members:

Bálint Mikes MD, see his PhD thesis here

Nóra Szarvas MSc, see her PhD thesis here

Zsigmond Jenei MD, see his PhD thesis here

Tímea Gombos MD, see her PhD thesis here
Melinda Zsuzsanna Szabó, research student
Zsófia Sébor, research student
Szigeti Antalné, Laboratory Assistant